The cyclizations of L-(+)-prolinol 1 derived from L-proline with (thio)phosphoro(-no)dichlorides 2 give 1,2,3-azaphosphaoxabicyclo[3.3.0] 3 consisting of unequal amounts of diastereoisomers, eight pairs of which have ...The cyclizations of L-(+)-prolinol 1 derived from L-proline with (thio)phosphoro(-no)dichlorides 2 give 1,2,3-azaphosphaoxabicyclo[3.3.0] 3 consisting of unequal amounts of diastereoisomers, eight pairs of which have been successfully separated by silica gel column chromatography or recrystallization.展开更多
Atomic force microscope(AFM) can be used to investigate the surface structuxes of different kinds materials, and N-(4-nitrophenyl)-(L)-prolinol (NPP),as an organic second-order nonlinear optical crystal, has very larg...Atomic force microscope(AFM) can be used to investigate the surface structuxes of different kinds materials, and N-(4-nitrophenyl)-(L)-prolinol (NPP),as an organic second-order nonlinear optical crystal, has very large nonlinear efficiency. With our homemade AFM instrument, the topographic images of NPP surface have been obtained, The NPP crystal was grown in acetone by solvent evaporation. The AFM results indicates that the surface structure of NPP (001) surface is in well agreement with the bulk structure determined by X-ray diffraction expermients without any reconstruction.展开更多
以廉价易得的方酸为原料,通过酯化,再与L-脯氨醇发生氨解反应,得到具有C2对称结构的手性L-脯氨醇方酰胺(分子式:C14H20N2O4),两步反应总收率67.5%.其结构经FT-IR、1 H NMR、13 C NMR、ESI-HRMS以及X-射线单晶衍射进行确证.该晶体属于斜...以廉价易得的方酸为原料,通过酯化,再与L-脯氨醇发生氨解反应,得到具有C2对称结构的手性L-脯氨醇方酰胺(分子式:C14H20N2O4),两步反应总收率67.5%.其结构经FT-IR、1 H NMR、13 C NMR、ESI-HRMS以及X-射线单晶衍射进行确证.该晶体属于斜方晶系,P212121空间群,晶胞参数:a=0.807 04(12)nm,b=0.901 36(13)nm,c=2.059 6(3)nm,α=β=γ=90.00°,V=1.498 2(4)nm3,Z=4,Dc=1.323g·cm-3,μ=0.100 mm-1,F(000)=640,最终残差因子R1=0.042 9,wR2=0.103 9.展开更多
文摘The cyclizations of L-(+)-prolinol 1 derived from L-proline with (thio)phosphoro(-no)dichlorides 2 give 1,2,3-azaphosphaoxabicyclo[3.3.0] 3 consisting of unequal amounts of diastereoisomers, eight pairs of which have been successfully separated by silica gel column chromatography or recrystallization.
文摘Atomic force microscope(AFM) can be used to investigate the surface structuxes of different kinds materials, and N-(4-nitrophenyl)-(L)-prolinol (NPP),as an organic second-order nonlinear optical crystal, has very large nonlinear efficiency. With our homemade AFM instrument, the topographic images of NPP surface have been obtained, The NPP crystal was grown in acetone by solvent evaporation. The AFM results indicates that the surface structure of NPP (001) surface is in well agreement with the bulk structure determined by X-ray diffraction expermients without any reconstruction.
