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Clinical Manifestation and Laboratory Characteristics of SARS-CoV-2Infection in Pregnant Women
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作者 Chunchen Wu Wenzhong Yang +4 位作者 Xiaoxue Wu Tianzhu Zhang Yaoyao Zhao Wei Ren Jianbo Xia 《Virologica Sinica》 SCIE CAS CSCD 2020年第3期305-310,共6页
The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) epidemic has become a major challenge to public health in China and other countries, considering its pathogenicity across all age groups. Pregnancy is a ... The severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) epidemic has become a major challenge to public health in China and other countries, considering its pathogenicity across all age groups. Pregnancy is a unique physiological condition, and is characterized by altered immunity and elevated hormone levels to actively tolerate the semiallogeneic fetus, which undergoes a sudden and substantial fluctuation during the immediate postpartum period. Changes in clinical features, laboratory characteristics, and imaging features of pregnant women during the pre-partum and postpartum periods require further elucidation. Here, we retrospectively analyzed the clinical features, laboratory characteristics, and imaging features of eight pregnant cases of SARS-CoV-2 infection during the pre-partum and post-partum periods. Our results showed that four of the eight pregnant women were asymptomatic before delivery but became symptomatic post-partum. Correspondingly, white blood cell(WBC) counts increased and lymphocyte(LYMPH) counts decreased. C-reactive protein(CRP) levels in the serum also increased to a higher level than those in general pregnancy.Therefore, it is imperative to closely monitor laboratory parameters including the WBC count, LYMPH count, and CRP,along with other imaging features in chest CT scans, to promptly prevent, diagnose, and treat a SARS-CoV-2 infection during pregnancy. 展开更多
关键词 SARS-CoV-2 Pregnant women Clinical manifestation laboratory characteristics IMMUNITY
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Analytical characteristics of a qPCR-based molecular diagnostic assay-conceptual considerations for laboratory personnel
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作者 Tanuj Shukla Prabhakar Rao Kaipa +1 位作者 Shesheer K Munpally Rachana Tripathi 《The Journal of Biomedical Research》 CAS 2014年第3期246-248,共3页
Dear Editor:Quantitative real-time PCR has revolutionized molecular diagnostics with its ease of use,increased sensitivity and specificity and low turnaround time.PCR/quantitative PCR(qPCR)-based assays offer a dis... Dear Editor:Quantitative real-time PCR has revolutionized molecular diagnostics with its ease of use,increased sensitivity and specificity and low turnaround time.PCR/quantitative PCR(qPCR)-based assays offer a distinct advantage over other serological/conventional diagnostic approaches.The ability to diagnose infectious diseases has benefited from the availability of US FDA approved and Conformite Europeenne(CE)-marked qPCR-based in-vitro diagnostic kits from international companies.The high-quality kits are calibrated with the World Health Organization(WHO)reference standards and the National Institute for Biological Standards and Control(NIBSC)standards. 展开更多
关键词 qPCR Analytical characteristics of a qPCR-based molecular diagnostic assay-conceptual considerations for laboratory personnel
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A LABORATORY INVESTIGATION OF CHARACTERISTICS OF TORNADO-LIKE VORTICES OVER VARIOUS ROUGH SURFACES
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作者 文字信贵 王允宽 《Acta meteorologica Sinica》 SCIE 1989年第4期506-515,共10页
In this paper,the effects of surface roughness on tornado-like vortices are studied in the laboratory for simulating tornado vortex at the Disaster Prevention Research Institute,Kyoto University,Japan. In the experime... In this paper,the effects of surface roughness on tornado-like vortices are studied in the laboratory for simulating tornado vortex at the Disaster Prevention Research Institute,Kyoto University,Japan. In the experiments,the distribution of the horizontal wind speed and direction at five different heights were measured with a hot-wire anemometer and a mini-vane.The characteristics of wind speed and direc- tion distribution for the tornado vortex on the various rough surfaces were first revealed with the simulative method in laboratory.By changing the swirl ratio(S=tanθ/2a)of simulation device,it is found that,the size of tornado-like vortex core will become almost identical,as the swirl ratio S exceeds a certain value (S>1.5). The experimental results can be used not only to explain the observed facts in the atmosphere but also to provide the experimental bases for some theoretical studies. 展开更多
关键词 A laboratory INVESTIGATION OF characteristics OF TORNADO-LIKE VORTICES OVER VARIOUS ROUGH SURFACES
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