Objective:To test two theories from traditional Chinese medicine:'exterior -interior relationship between the lung and large intestine' and 'treating from the intestine principle for lung disorders'.Th...Objective:To test two theories from traditional Chinese medicine:'exterior -interior relationship between the lung and large intestine' and 'treating from the intestine principle for lung disorders'.The influence of intestine-based treatment using Xuan Bai Cheng Qi Tang (XBCQT) on the concentration of three trace elements-copper (Cu),zinc (Zn),and manganese (Mn)-was observed in the tissues of the lung,small intestine,large intestine,and stomach of rats suffering from chronic obstructive pulmonary disease (COPD).Methods:Thirty-five male Wistar rats were divided randomly and equally into five groups:control;model;Fei treatment (A);Chang treatment (B);and Fei-Chang treatment (C).A rat model of COPD was prepared by tracheal injection of lipopolysaccharide plus exposure to cigarette smoke.Treatments with medicinal herbs started day-22 of administration and exposure to cigarette smoke for 7 days.The control group and model group were administered physiologic (0.9%) saline solution via the stomach.After 7 days of intervention,the tissues of the lung,small intestine,large intestine,and stomach were removed.Inductively coupled plasma-atomic emission spectroscopy was used to detect the levels of Cu,Zn,and Mn in those tissues.Results:Compared with the control group,the Cu concentration in the tissues of the small intestine,large intestine,and stomach increased significantly in the model group (P <.05);the Mn concentration in the tissues of the lung,large intestine,and stomach increased significantly in the model group (P <.05);the Zn concentration in the tissues of the lung and large intestine decreased significantly in the model group (P <.05).In comparison of the model group:the Cu concentration in the tissues of the lung and large intestine decreased significantly in the B group (P <.05);the Mn concentration in the tissues of the lung,small intestine,and large intestine decreased significantly in the B group (P <.05);the Zn concentration in the tissues of the lung,small intestine,and large intestine increased significantly in the B group (P <.05).For the A group versus C group comparison,the Zn concentration in the tissues of the small intestine and stomach increased significantly in the latter (P <.05).Conclusion:This study showed that 'treating from the intestine' using Xuan Bai Cheng Qi Tang and its modified formulae can regulate the concentration of trace elements in the main organs of COPD rats.This may be one of the mechanisms for intestine-based treatment for COPD.展开更多
Tunable diode laser absorption spectroscopy (TDLAS) has been widely employed in atmospheric trace gases detecting and industrial control due to its high sensitivity, selectivity, and rapidity of response. An open pa...Tunable diode laser absorption spectroscopy (TDLAS) has been widely employed in atmospheric trace gases detecting and industrial control due to its high sensitivity, selectivity, and rapidity of response. An open path TDLAS system is developed for monitoring large scale methane leakage around the oil refinery. The tunable distributed feedback (DFB) diode laser emits at 1.65 pro. In order to enhance the sensitivity, a system combining long open path and second harmonic detection technique is developed. The test results show that the time resolution is less than 0.1 second and the detection limit is lower than 3.6 ppmv. This system is adapted for monitoring a large scale methane concentration changing trend instead of measuring its absolute concentration.展开更多
Southern Hunan Province is famous for its intensive rare, radioactive and other metal elements’ mineralizations. There is a relation between the basaltic rocks and mineralizations in space, time and ore forming eleme...Southern Hunan Province is famous for its intensive rare, radioactive and other metal elements’ mineralizations. There is a relation between the basaltic rocks and mineralizations in space, time and ore forming elements. The Jurassic Cretaceous (204\81 Ma) basaltic rocks consists mainly of alkali\|basalt and tholeiitic basalt formed in plate environment. Trace elements and Sr, Nd, Pb isotopic compositions show that the regional mantle source was metasomatized shortly before the partial melting. The alkali basalt and tholeiitic basalt might be 3%\5% and 10%\15% of the partial melting of the enriched mantle source respectively. Obviously the enrichment of the regional mantle played an important role in formation of the large and super\|large deposits in southern Hunan Province.展开更多
文摘Objective:To test two theories from traditional Chinese medicine:'exterior -interior relationship between the lung and large intestine' and 'treating from the intestine principle for lung disorders'.The influence of intestine-based treatment using Xuan Bai Cheng Qi Tang (XBCQT) on the concentration of three trace elements-copper (Cu),zinc (Zn),and manganese (Mn)-was observed in the tissues of the lung,small intestine,large intestine,and stomach of rats suffering from chronic obstructive pulmonary disease (COPD).Methods:Thirty-five male Wistar rats were divided randomly and equally into five groups:control;model;Fei treatment (A);Chang treatment (B);and Fei-Chang treatment (C).A rat model of COPD was prepared by tracheal injection of lipopolysaccharide plus exposure to cigarette smoke.Treatments with medicinal herbs started day-22 of administration and exposure to cigarette smoke for 7 days.The control group and model group were administered physiologic (0.9%) saline solution via the stomach.After 7 days of intervention,the tissues of the lung,small intestine,large intestine,and stomach were removed.Inductively coupled plasma-atomic emission spectroscopy was used to detect the levels of Cu,Zn,and Mn in those tissues.Results:Compared with the control group,the Cu concentration in the tissues of the small intestine,large intestine,and stomach increased significantly in the model group (P <.05);the Mn concentration in the tissues of the lung,large intestine,and stomach increased significantly in the model group (P <.05);the Zn concentration in the tissues of the lung and large intestine decreased significantly in the model group (P <.05).In comparison of the model group:the Cu concentration in the tissues of the lung and large intestine decreased significantly in the B group (P <.05);the Mn concentration in the tissues of the lung,small intestine,and large intestine decreased significantly in the B group (P <.05);the Zn concentration in the tissues of the lung,small intestine,and large intestine increased significantly in the B group (P <.05).For the A group versus C group comparison,the Zn concentration in the tissues of the small intestine and stomach increased significantly in the latter (P <.05).Conclusion:This study showed that 'treating from the intestine' using Xuan Bai Cheng Qi Tang and its modified formulae can regulate the concentration of trace elements in the main organs of COPD rats.This may be one of the mechanisms for intestine-based treatment for COPD.
文摘通过焊接热模拟研究了在超大线能量下焊接时Al元素、Mg元素和Ti元素含量对EH36高强船板钢热影响区粗晶区组织、性能的影响规律,采用Thermo-Calc热力学计算与SEM,EDS测试相结合的方法揭示了Al元素、Mg元素和Ti元素含量与母材中氧化物类型、尺寸、数量及粗晶区相变的关系.结果表明,Al_(2)O_(3)无法诱导针状铁素体相变,当Al元素质量分数低于0.005%时,钢中可形成Mg元素、Ti元素或其复合氧化物,可促进粗晶区针状铁素体相变.Mg元素和Ti元素联合添加时,当Mg元素质量分数由0.0042%降低为0.0013%,氧化物类型由MgO转变为Mg_(2)TiO_(4),经统计20个视场内的氧化物数量由408个提高到503个,平均直径由1.37μm减小到1.10μm,显著提高了非均匀形核的比表面积,抑制了晶界铁素体的形成,使t8/5=300 s时粗晶区热模拟试样-20℃冲击吸收能量由43 J提升到127 J.
基金This project was supported by the National Natural Science Foundation of China (No. 10274080)the National High Technology Research and Development Program of China (No. 2003AA641010).
文摘Tunable diode laser absorption spectroscopy (TDLAS) has been widely employed in atmospheric trace gases detecting and industrial control due to its high sensitivity, selectivity, and rapidity of response. An open path TDLAS system is developed for monitoring large scale methane leakage around the oil refinery. The tunable distributed feedback (DFB) diode laser emits at 1.65 pro. In order to enhance the sensitivity, a system combining long open path and second harmonic detection technique is developed. The test results show that the time resolution is less than 0.1 second and the detection limit is lower than 3.6 ppmv. This system is adapted for monitoring a large scale methane concentration changing trend instead of measuring its absolute concentration.
文摘Southern Hunan Province is famous for its intensive rare, radioactive and other metal elements’ mineralizations. There is a relation between the basaltic rocks and mineralizations in space, time and ore forming elements. The Jurassic Cretaceous (204\81 Ma) basaltic rocks consists mainly of alkali\|basalt and tholeiitic basalt formed in plate environment. Trace elements and Sr, Nd, Pb isotopic compositions show that the regional mantle source was metasomatized shortly before the partial melting. The alkali basalt and tholeiitic basalt might be 3%\5% and 10%\15% of the partial melting of the enriched mantle source respectively. Obviously the enrichment of the regional mantle played an important role in formation of the large and super\|large deposits in southern Hunan Province.