We used data from the Xinjiang Digital Seismic Network and PSD( Power Spectral Density) method to perform noise level assessment for six stations. We calculated the median of the power spectral density to evaluate the...We used data from the Xinjiang Digital Seismic Network and PSD( Power Spectral Density) method to perform noise level assessment for six stations. We calculated the median of the power spectral density to evaluate the noise level of different stations. After the comparison of the power spectral density of different stations and the airgun signal recognition,we found that noise level of stations with recognizable airgun source signals is lower than that of stations without recognizable signals. The largest difference of the power spectral density is 40 d B,and the smallest is 15 d B. Finally,we found that the failure to recognize the signal of airgun sources at some stations is due to the noise level.展开更多
As this is the first time a large volume airgun has been excited in the "Yangtse River Geoscience Project",it is necessary to study the time-frequency characteristic based on the linear stacked seismic data ...As this is the first time a large volume airgun has been excited in the "Yangtse River Geoscience Project",it is necessary to study the time-frequency characteristic based on the linear stacked seismic data from records from portable stations near the fixed fields and seismic stations. Airgun signal propagation distances were detected using stacked seismic data to analyze the environmental impact on signal propagation distance. The results showed that:( 1) the airgun signal produced by bubble pulses,pressure pulses and the surface wave can be received by a portable station near the fixed field;( 2) the dominant frequency of a bubble at 5Hz or so can be received by both near-field stations and far-field stations,pressure pulses rapidly weaken and the dominant frequency bands get narrower as epicentral distance increases;( 3) the longest spread distance of signal is 260 km,the nearest is 180 km,and the signal can travel further in the evening.展开更多
With volume size increasing, it is necessary to develop a highly efficient compression algorithm, which is suitable for progressive refinement between the data server and the browsing client. For three-dimensional lar...With volume size increasing, it is necessary to develop a highly efficient compression algorithm, which is suitable for progressive refinement between the data server and the browsing client. For three-dimensional large volume data, an efficient hierarchical algorithm based on wavelet compression was presented, using intra-band dependencies of wavelet coefficients. Firstly, after applying blockwise hierarchical wavelet decomposition to large volume data, the block significance map was obtained by using one bit to indicate significance or insignificance of the block. Secondly, the coefficient block was further subdivided into eight sub-blocks if any significant coefficient existed in it, and the process was repeated, resulting in an incomplete octree. One bit was used to indicate significance or insignificance, and only significant coefficients were stored in the data stream. Finally, the significant coefficients were quantified and compressed by arithmetic coding. The experimental results show that the proposed algorithm achieves good compression ratios and is suited for random access of data blocks. The results also show that the proposed algorithm can be applied to progressive transmission of 3D volume data.展开更多
BACKGROUND Refractory ascites has a 1-year survival rate of 50%.In selected patients,treatment options include liver transplantation(LT)or transjugular intrahepatic portosystemic stent shunt(TIPSS).AIM To assess the o...BACKGROUND Refractory ascites has a 1-year survival rate of 50%.In selected patients,treatment options include liver transplantation(LT)or transjugular intrahepatic portosystemic stent shunt(TIPSS).AIM To assess the outcomes of patients who underwent a TIPSS compared to large volume paracentesis(LVP).METHODS Retrospective study of patients who underwent a covered TIPSS or LVP for refractory or recurrent ascites over 7 years.Primary outcome was transplant-free survival(TFS).Further analysis was done with propensity score matching(PSM).RESULTS There were 150 patients[TIPSS group(n=75),LVP group(n=75)].Seven patients in the TIPSS group underwent LT vs 22 patients in the LVP group.Overall median follow up,20(0.47-179.53)mo.In the whole cohort,there was no difference in TFS[hazard ratio(HR):0.80,95%confidence interval(CI):0.54-1.21];but lower de novo hepatic encephalopathy with LVP(HR:95%CI:0.20-0.96).These findings were confirmed following PSM analysis.On multivariate analysis albumin and hepatocellular carcinoma at baseline were associated with TFS.CONCLUSION Covered TIPSS results in similar TFS compared to LVP in cirrhotic patients with advanced liver failure.Liver transplant assessment should be considered in all potential candidates for TIPSS.Further controlled studies are recommended to select appropriate patients for TIPSS.展开更多
in this paper,we prove that a complete n-dimensional Riemannian manifold with nonnegative kth-Ricci curvature, large volume growth has finite topological type provided that lim r→∞{(vol[B(p.r]/ωnrn-αM)rk(n-1...in this paper,we prove that a complete n-dimensional Riemannian manifold with nonnegative kth-Ricci curvature, large volume growth has finite topological type provided that lim r→∞{(vol[B(p.r]/ωnrn-αM)rk(n-1)/k+1(1-α/2)}≤for some COllstant ε〉0 We also prove that a conlplete Riemannian manifold with nonnegative kth-Ricci curvature and undler some pinching conditions is diffeomorphic to R^n.展开更多
Construction of mass concrete structures face more challenges in temperature difference and complex stress under low temperature than the ambient temperature. It has been proved by the practice that, not only improvin...Construction of mass concrete structures face more challenges in temperature difference and complex stress under low temperature than the ambient temperature. It has been proved by the practice that, not only improving tensile strength of structural concrete as soon as possible and removing of constrain as much as possible, but also calculation of the thermal stress in the process of construction and maintenance, controlling structure of concrete tensile strength and temperature difference stress ratio can ensure the safety and defect-free.展开更多
Large volume airgun arrays have been widely used in exploring and monitoring underground structures for nearly a decade.Nowadays,large volume airgun arrays adopt the synchronous excitation mode,and source characterist...Large volume airgun arrays have been widely used in exploring and monitoring underground structures for nearly a decade.Nowadays,large volume airgun arrays adopt the synchronous excitation mode,and source characteristics are controlled by the source signal of a single airgun,which to some extent limits its application.In order to realize the asynchronous excitation of the airgun array,we developed a new firing system for the airgun array,and carried out a field experiment in the Binchuan Fixed Airgun Signal Transmission station to study the influences of the asynchronous excitation on the source signal.The experimental results show that:the newly developed airgun array firing system can ignite the airguns according to the setting time series with high precision.By designing the excitation time series,the asynchronous excitation can enhance the energy of airgun source signal at 3-5 Hz,and reduce the energy of pressure pulse wave at 6-18 Hz.The signal detection capability of the asynchronous excitation with time series mode is equivalent to the synchronous excitation.展开更多
Huntington'sdisease(HD)isahereditary neurodegenerative disorder for which there is currently no effectivetreatmentavailable.Consequently,the development of appropriate disease models is critical to thoroughly inve...Huntington'sdisease(HD)isahereditary neurodegenerative disorder for which there is currently no effectivetreatmentavailable.Consequently,the development of appropriate disease models is critical to thoroughly investigate disease progression.The genetic basis of HD involves the abnormal expansion of CAG repeats in the huntingtin(HTT)gene,leading to the expansion of a polyglutamine repeat in the HTT protein.Mutant HTT carrying the expanded polyglutamine repeat undergoes misfolding and forms aggregates in the brain,which precipitate selective neuronal loss in specific brain regions.Animal models play an important role in elucidating the pathogenesis of neurodegenerative disorders such as HD and in identifying potential therapeutic targets.Due to the marked species differences between rodents and larger animals,substantial efforts have been directed toward establishing large animal models for HD research.These models are pivotal for advancing the discovery of novel therapeutic targets,enhancing effective drug delivery methods,and improving treatment outcomes.We have explored the advantages of utilizing large animal models,particularly pigs,in previous reviews.Since then,however,significant progress has been made in developing more sophisticated animal models that faithfully replicate the typical pathology of HD.In the current review,we provide a comprehensive overview of large animal models of HD,incorporating recent findings regarding the establishment of HD knock-in(KI)pigs and their genetic therapy.We also explore the utilization of large animal models in HD research,with a focus on sheep,non-human primates(NHPs),and pigs.Our objective is to provide valuable insights into the application of these large animal models for the investigation and treatment of neurodegenerative disorders.展开更多
This article elucidates the concept of large model technology,summarizes the research status of large model technology both domestically and internationally,provides an overview of the application status of large mode...This article elucidates the concept of large model technology,summarizes the research status of large model technology both domestically and internationally,provides an overview of the application status of large models in vertical industries,outlines the challenges and issues confronted in applying large models in the oil and gas sector,and offers prospects for the application of large models in the oil and gas industry.The existing large models can be briefly divided into three categories:large language models,visual large models,and multimodal large models.The application of large models in the oil and gas industry is still in its infancy.Based on open-source large language models,some oil and gas enterprises have released large language model products using methods like fine-tuning and retrieval augmented generation.Scholars have attempted to develop scenario-specific models for oil and gas operations by using visual/multimodal foundation models.A few researchers have constructed pre-trained foundation models for seismic data processing and interpretation,as well as core analysis.The application of large models in the oil and gas industry faces challenges such as current data quantity and quality being difficult to support the training of large models,high research and development costs,and poor algorithm autonomy and control.The application of large models should be guided by the needs of oil and gas business,taking the application of large models as an opportunity to improve data lifecycle management,enhance data governance capabilities,promote the construction of computing power,strengthen the construction of“artificial intelligence+energy”composite teams,and boost the autonomy and control of large model technology.展开更多
Shallow convection plays an important role in transporting heat and moisture from the near-surface to higher altitudes,yet its parameterization in numerical models remains a great challenge,partly due to the lack of h...Shallow convection plays an important role in transporting heat and moisture from the near-surface to higher altitudes,yet its parameterization in numerical models remains a great challenge,partly due to the lack of high-resolution observations.This study describes a large eddy simulation(LES)dataset for four shallow convection cases that differ primarily in inversion strength,which can be used as a surrogate for real data.To reduce the uncertainty in LES modeling,three different large eddy models were used,including SAM(System for Atmospheric Modeling),WRF(Weather Research and Forecasting model),and UCLA-LES.Results show that the different models generally exhibit similar behavior for each shallow convection case,despite some differences in the details of the convective structure.In addition to grid-averaged fields,conditionally sampled variables,such as in-cloud moisture and vertical velocity,are also provided,which are indispensable for calculation of the entrainment/detrainment rate.Considering the essentiality of the entraining/detraining process in the parameterization of cumulus convection,the dataset presented in this study is potentially useful for validation and improvement of the parameterization of shallow convection.展开更多
As one of the most common river patterns in nature,meandering river has very complex flow structures in its curved channel bends,including secondary flow structure and primary flow velocity redistributions.To date,mos...As one of the most common river patterns in nature,meandering river has very complex flow structures in its curved channel bends,including secondary flow structure and primary flow velocity redistributions.To date,most of the studies have been carried out on the flow structures in channel bends with unavoidable influences from inlet and outlet boundaries,while a streamwise periodic boundary can overcome this shortcoming elegantly.In this paper,large eddy simulations(LES)are employed to investigate the complex flow structures in periodically continuous sharp sine-generated bends.The influence of width-to-depth ratios and dimensionless curvature radiuses are studied.The results highlight two additional vortex structures beyond the commonly known secondary currents:The recirculation zone(RZ)and the inner bank cell(IBC).The width-to-depth ratio shows the determining effect on the recirculation zone.The size of recirculation zone is usually bigger in sine-generated-curve(SGC)channel with large width-to-depth ratios.The biggest recirculation zones appear between the zero-curvature section and the apex section.The inner bank cell only forms in SGC channels with small width-to-depth ratios and low curvature.For SGC channel with large width-to-depth ratios,only one circulation cell is observed near the inner bank.The spatial variations of turbulent features are also revealed by statistical analysis based on the LES sampling data.Results highlight remarkable effect of width-to-depth ratio and dimensionless curvature radius on the turbulent kinetic energy(TKE)and bed shear stress in SGC channels.展开更多
There are lots of researches on fixture layout optimization for large thin-walled parts.Current researches focus on the positioning problem,i.e.,optimizing the positions of a constant number of fixtures.However,how to...There are lots of researches on fixture layout optimization for large thin-walled parts.Current researches focus on the positioning problem,i.e.,optimizing the positions of a constant number of fixtures.However,how to determine the number of fixtures is ignored.In most cases,the number of fixtures located on large thin-walled parts is determined based on engineering experience,which leads to huge fixture number and extra waste.Therefore,this paper constructs an optimization model to minimize the number of fixtures.The constraints are set in the optimization model to ensure that the part deformation is within the surface profile tolerance.In addition,the assembly gap between two parts is also controlled.To conduct the optimization,this paper develops an improved particle swarm optimization(IPSO)algorithm by integrating the shrinkage factor and adaptive inertia weight.In the algorithm,particles are encoded according to the fixture position.Each dimension of the particle is assigned to a sub-region by constraining the optional position range of each fixture to improve the optimization efficiency.Finally,a case study on ship curved panel assembly is provided to prove that our method can optimize the number of fixtures while meeting the assembly quality requirements.This research proposes a method to optimize the number of fixtures,which can reduce the number of fixtures and achieve deformation control at the same time.展开更多
Biodiversity,large trees,and environmental conditions such as climate and soil have important effects on forest carbon stocks.However,recent studies in temperate forests suggest that the relative importance of these f...Biodiversity,large trees,and environmental conditions such as climate and soil have important effects on forest carbon stocks.However,recent studies in temperate forests suggest that the relative importance of these factors depends on tree mycorrhizal associations,whereby large-tree effects may be driven by ectomycorrhizal(EM)trees,diversity effects may be driven by arbuscular mycorrhizal(AM)trees,and environment effects may depend on differential climate and soil preferences of AM and EM trees.To test this hypothesis,we used forest-inventory data consisting of over 80,000 trees from 631 temperate-forest plots(30 m×30 m)across Northeast China to examine how biodiversity(species diversity and ecological uniqueness),large trees(top 1%of tree diameters),and environmental factors(climate and soil nutrients)differently regulate aboveground carbon stocks of AM trees,EM trees,and AM and EM trees combined(i.e.total aboveground carbon stock).We found that large trees had a positive effect on both AM and EM tree carbon stocks.However,biodiversity and environmental factors had opposite effects on AM vs.EM tree carbon stocks.Specifically,the two components of biodiversity had positive effects on AM tree carbon stocks,but negative effects on EM tree carbon stocks.Environmental heterogeneity(mean annual temperature and soil nutrients)also exhibited contrasting effects on AM and EM tree carbon stocks.Consequently,for the total carbon stock,the positive large-tree effect far surpasses the diversity and environment effect.This is mainly because when integrating AM and EM tree carbon stock into total carbon stock,the opposite diversity-effect(also environment-effect)on AM vs.EM tree carbon stock counteracts each other while the consistent positive large-tree effect on AM and EM tree carbon stock is amplified.In summary,this study emphasized a mycorrhizal viewpoint to better understand the determinants of overarching aboveground carbon profile across regional forests.展开更多
A study was conducted to analyze the deformation mechanism of strongly weathered quartz schist in the Daliangshan Tunnel,located in the western Transverse Mountain area.A large deformation problem was experienced duri...A study was conducted to analyze the deformation mechanism of strongly weathered quartz schist in the Daliangshan Tunnel,located in the western Transverse Mountain area.A large deformation problem was experienced during the tunnel construction.To mitigate this problem,a support system was designed incorporating negative Poisson ratio(NPR)anchor cables with negative Poisson ratio effect.Physical model experiments,field experiments,and numerical simulation experiments were conducted to investigate the compensation mechanical behavior of NPR anchor cables.The large deformations of soft rocks in the Daliangshan Tunnel are caused by a high ground stress,a high degree of joint fracture development,and a high degree of surrounding rock fragmentation.A compensation mechanics support system combining long and short NPR anchor cables was suggested to provide sufficient counter-support force(approximately 350 kN)for the surrounding rock inside the tunnel.Comparing the NPR anchor cable support system with the original support system used in the Daliangshan tunnel showed that an NPR anchor cable support system,combining cables of 6.3 m and 10.3 m in length,effectively prevented convergence of surrounding rock deformation,and the integrated settlement convergence value remained below 300 mm.This study provides an effective scientific basis for resolving large deformation problems in deeply buried soft rocks in western transverse mountain areas.展开更多
Comprehensive research has been implemented to raise the efficiency of the geochemical survey of stream sediments(SSs)that formed under the cryolithogenesis conditions.The authors analysed the composition,structure an...Comprehensive research has been implemented to raise the efficiency of the geochemical survey of stream sediments(SSs)that formed under the cryolithogenesis conditions.The authors analysed the composition,structure and specific features of the formation of exogenous anomalous geochemical fields(AGFs)identified through SSs of large river valleys of IV order.In our case,these were the valleys of Maly Ken,Ken and Tap Rivers.These rivers are located in the central and southern parts of the Balygychan-Sugoy trough enclosed in the Magadan region,North-East of Russia.The authors proposed a new technique to sample loose alluvium of SSs in the large river valleys along the profiles.The profiles were located across the valleys.The AGFs of Au,Ag,Pb,Zn,Sn,Bi,Mo and W were studied.Correlations between elements have been established.These elements are the main indicator elements of Au-Ag,Ag-Pb,Sn-Ag,Mo-W and Sn-W mineralization occurring on the sites under study.The results obtained were compared with the results of geochemical surveys of SSs.It is concluded that the AGFs recognized along the profiles reflect the composition and structure of eroded and drained ore zones,uncover completely and precisely the pattern of element distribution in loose sediments of large water flows.The alluvium fraction<0.25 mm seems to be most significant in a practical sense,as it concentrated numerous ore elements.Sampling of this fraction in the river valleys of IV order does not cause any difficulty,for this kind of material is plentiful.The developed technique of alluvium sampling within large river valleys is efficient in searching for diverse mineralization at all stages of prognostic prospecting.It is applicable for geochemical survey of SSs performed at different scales both in the North-East of Russia,as well as other regions with similar climatic conditions,where the SSs are formed under the cryolithogenesis conditions.展开更多
In order to improve rib stability,failure criteria and instability mode of a thick coal seam with inter-band rock layer are analysed in this study.A three-dimensional mechanical model is established for the rib by con...In order to improve rib stability,failure criteria and instability mode of a thick coal seam with inter-band rock layer are analysed in this study.A three-dimensional mechanical model is established for the rib by considering the rock layer.A safety factor is defined foy the rib,and it is observed that the safety factor exhibits a positive correlation with the thickness and strength of the inter-band rock.A calculation method for determining critical parameters of the rock layer is presented to ensure the rib stability.It is revealed that incomplete propagation of the fracture at the hard rock constitutes a fundamental prerequisite for ensuring the rib stability.The influence of the position of the inter-band rock in the coal seam on failure mechanism of the rib was thoroughly investigated by developing a series of physical models for the rib at the face area.The best position for the inter-band rock in the coal seam is at a height of 1.5 m away from the roof line,which tends to provide a good stability state for the rib.For different inter-band rock positions,two ways of controlling rib by increasing supports stiffness and flexible grouting reinforcement are proposed.展开更多
Hierarchical networks are frequently encountered in animal groups,gene networks,and artificial engineering systems such as multiple robots,unmanned vehicle systems,smart grids,wind farm networks,and so forth.The struc...Hierarchical networks are frequently encountered in animal groups,gene networks,and artificial engineering systems such as multiple robots,unmanned vehicle systems,smart grids,wind farm networks,and so forth.The structure of a large directed hierarchical network is often strongly influenced by reverse edges from lower-to higher-level nodes,such as lagging birds’howl in a flock or the opinions of lowerlevel individuals feeding back to higher-level ones in a social group.This study reveals that,for most large-scale real hierarchical networks,the majority of the reverse edges do not affect the synchronization process of the entire network;the synchronization process is influenced only by a small part of these reverse edges along specific paths.More surprisingly,a single effective reverse edge can slow down the synchronization of a huge hierarchical network by over 60%.The effect of such edges depends not on the network size but only on the average in-degree of the involved subnetwork.The overwhelming majority of active reverse edges turn out to have some kind of“bunching”effect on the information flows of hierarchical networks,which slows down synchronization processes.This finding refines the current understanding of the role of reverse edges in many natural,social,and engineering hierarchical networks,which might be beneficial for precisely tuning the synchronization rhythms of these networks.Our study also proposes an effective way to attack a hierarchical network by adding a malicious reverse edge to it and provides some guidance for protecting a network by screening out the specific small proportion of vulnerable nodes.展开更多
In this study,the Mg-3Zn-0.5Zr-χNd(χ=0,0.6)alloys were subjected to final rolling treatment with large deformation of 50%.The impact of annealing temperatures on the microstructure and mechanical properties was inve...In this study,the Mg-3Zn-0.5Zr-χNd(χ=0,0.6)alloys were subjected to final rolling treatment with large deformation of 50%.The impact of annealing temperatures on the microstructure and mechanical properties was investigated.The rolled Mg-3Zn-0.5Zr-0.6Nd alloy exhibited an ultimate tensile strength of 386 MPa,a yield strength of 361 MPa,and an elongation of 7.1%.Annealing at different temperatures resulted in reduced strength and obviously increased elongation for both alloys.Optimal mechanical properties for the Mg-3Zn-0.5Zr-0.6Nd alloy were achieved after annealing at 200℃,with an ultimate tensile strength of 287 MPa,a yield strength of 235 MPa,and an elongation of 26.1%.The numerous deformed microstructures,twins,and precipitated phases in the rolled alloy could impede the deformation at room temperature and increase the work hardening rate.After annealing,a decrease in the work hardening effect and an increase in the dynamic recovery effect were obtained due to the formation of fine equiaxed grains,and the increased volume fraction of precipitated phases,which significantly improved the elongation of the alloy.Additionally,the addition of Nd element could enhance the annealing recrystallization rate,reduce the Schmid factor difference between basal and prismatic slip systems,facilitate multi-system slip initiation and improve the alloy plasticity.展开更多
Most viruses and transposons serve as effective carriers for the introduction of foreign DNA up to 11 kb into vertebrate genomes.However,their activity markedly diminishes with payloads exceeding 11 kb.Expanding the p...Most viruses and transposons serve as effective carriers for the introduction of foreign DNA up to 11 kb into vertebrate genomes.However,their activity markedly diminishes with payloads exceeding 11 kb.Expanding the payload capacity of transposons could facilitate more sophisticated cargo designs,improving the regulation of expression and minimizing mutagenic risks associated with molecular therapeutics,metabolic engineering,and transgenic animal production.In this study,we improved the Tol2 transposon by increasing protein expression levels using a translational enhancer(QBI SP163,ST)and enhanced the nuclear targeting ability using the nuclear localization protein H2B(SHT).The modified Tol2 and ST transposon efficiently integrated large DNA cargos into human cell cultures(H1299),comparable to the well-established super PiggyBac system.Furthermore,mRNA from ST and SHT showed a significant increase in transgene delivery efficiency of large DNA payloads(8 kb,14 kb,and 24 kb)into zebrafish(Danio rerio).This study presents a modified Tol2 transposon as an enhanced nonviral vector for the delivery of large DNA payloads in transgenic applications.展开更多
In order to effectively reduce energy consumption and increase range mile,new energy vehicles represented by Tesla have greatly aroused the application of integrated magnesium(Mg)alloy die casting technology in automo...In order to effectively reduce energy consumption and increase range mile,new energy vehicles represented by Tesla have greatly aroused the application of integrated magnesium(Mg)alloy die casting technology in automobiles.Previously,the application of Mg alloys in automobiles,especially in automotive cockpit components,is quite extensive,while it has almost disappeared for a period of time due to its relatively high cost,causing a certain degree of information loss in the application technology of Mg alloy parts in automobiles.The rapid development of automotive technology has led to a higher requirement for the automotive components compared with those traditional one.Therefore,whatever the components themselves,or the Mg alloy materials and die casting process have to face an increasing challenge,needing to be upgraded.In addition,owing to its high integration characteristics,the application of Mg alloy die casting technology in large-sized and thin-walled automotive parts has inherent advantages and needs to be expanded urgently.Indeed,it necessitates exploring advance Mg alloys and new product structures and optimizing die casting processes.This article summarizes and analyzes the development status of thin-walled and large-sized die casting Mg alloy parts in passenger car cockpit and corresponding material selection methods,die casting processes as well as mold design techniques.Furthermore,this work will aid researchers in establishing a comprehensive understanding of the manufacture of thin-walled and large-sized die casting Mg alloy parts in automobile cockpit.It will also assist them in developing new Mg alloys with improved comprehensive performance and new processes to meet the high requirements for die casting automotive components.展开更多
基金jointly funded by the Special Fund of Earthquake Industry(201508008)National Natural Science Foundation of China(41474051)Scientific Institution Innovation and Development Fund of Xinjiang Uygur Autonomous Region(201316)
文摘We used data from the Xinjiang Digital Seismic Network and PSD( Power Spectral Density) method to perform noise level assessment for six stations. We calculated the median of the power spectral density to evaluate the noise level of different stations. After the comparison of the power spectral density of different stations and the airgun signal recognition,we found that noise level of stations with recognizable airgun source signals is lower than that of stations without recognizable signals. The largest difference of the power spectral density is 40 d B,and the smallest is 15 d B. Finally,we found that the failure to recognize the signal of airgun sources at some stations is due to the noise level.
基金jointly sponsored by the Special Fund for Earthquake Scientific Research in the Public Welfare of China Earthquake Administration(2015419015)the National Natural Science Foundation of China(41474071)
文摘As this is the first time a large volume airgun has been excited in the "Yangtse River Geoscience Project",it is necessary to study the time-frequency characteristic based on the linear stacked seismic data from records from portable stations near the fixed fields and seismic stations. Airgun signal propagation distances were detected using stacked seismic data to analyze the environmental impact on signal propagation distance. The results showed that:( 1) the airgun signal produced by bubble pulses,pressure pulses and the surface wave can be received by a portable station near the fixed field;( 2) the dominant frequency of a bubble at 5Hz or so can be received by both near-field stations and far-field stations,pressure pulses rapidly weaken and the dominant frequency bands get narrower as epicentral distance increases;( 3) the longest spread distance of signal is 260 km,the nearest is 180 km,and the signal can travel further in the evening.
基金Supported by Natural Science Foundation of China (No. 60373061).
文摘With volume size increasing, it is necessary to develop a highly efficient compression algorithm, which is suitable for progressive refinement between the data server and the browsing client. For three-dimensional large volume data, an efficient hierarchical algorithm based on wavelet compression was presented, using intra-band dependencies of wavelet coefficients. Firstly, after applying blockwise hierarchical wavelet decomposition to large volume data, the block significance map was obtained by using one bit to indicate significance or insignificance of the block. Secondly, the coefficient block was further subdivided into eight sub-blocks if any significant coefficient existed in it, and the process was repeated, resulting in an incomplete octree. One bit was used to indicate significance or insignificance, and only significant coefficients were stored in the data stream. Finally, the significant coefficients were quantified and compressed by arithmetic coding. The experimental results show that the proposed algorithm achieves good compression ratios and is suited for random access of data blocks. The results also show that the proposed algorithm can be applied to progressive transmission of 3D volume data.
文摘BACKGROUND Refractory ascites has a 1-year survival rate of 50%.In selected patients,treatment options include liver transplantation(LT)or transjugular intrahepatic portosystemic stent shunt(TIPSS).AIM To assess the outcomes of patients who underwent a TIPSS compared to large volume paracentesis(LVP).METHODS Retrospective study of patients who underwent a covered TIPSS or LVP for refractory or recurrent ascites over 7 years.Primary outcome was transplant-free survival(TFS).Further analysis was done with propensity score matching(PSM).RESULTS There were 150 patients[TIPSS group(n=75),LVP group(n=75)].Seven patients in the TIPSS group underwent LT vs 22 patients in the LVP group.Overall median follow up,20(0.47-179.53)mo.In the whole cohort,there was no difference in TFS[hazard ratio(HR):0.80,95%confidence interval(CI):0.54-1.21];but lower de novo hepatic encephalopathy with LVP(HR:95%CI:0.20-0.96).These findings were confirmed following PSM analysis.On multivariate analysis albumin and hepatocellular carcinoma at baseline were associated with TFS.CONCLUSION Covered TIPSS results in similar TFS compared to LVP in cirrhotic patients with advanced liver failure.Liver transplant assessment should be considered in all potential candidates for TIPSS.Further controlled studies are recommended to select appropriate patients for TIPSS.
文摘in this paper,we prove that a complete n-dimensional Riemannian manifold with nonnegative kth-Ricci curvature, large volume growth has finite topological type provided that lim r→∞{(vol[B(p.r]/ωnrn-αM)rk(n-1)/k+1(1-α/2)}≤for some COllstant ε〉0 We also prove that a conlplete Riemannian manifold with nonnegative kth-Ricci curvature and undler some pinching conditions is diffeomorphic to R^n.
文摘Construction of mass concrete structures face more challenges in temperature difference and complex stress under low temperature than the ambient temperature. It has been proved by the practice that, not only improving tensile strength of structural concrete as soon as possible and removing of constrain as much as possible, but also calculation of the thermal stress in the process of construction and maintenance, controlling structure of concrete tensile strength and temperature difference stress ratio can ensure the safety and defect-free.
基金sponsored by the National Key R&D Program of China(2018YFC1503202)the National Natural Science Foundation of China(41574052,41790463)
文摘Large volume airgun arrays have been widely used in exploring and monitoring underground structures for nearly a decade.Nowadays,large volume airgun arrays adopt the synchronous excitation mode,and source characteristics are controlled by the source signal of a single airgun,which to some extent limits its application.In order to realize the asynchronous excitation of the airgun array,we developed a new firing system for the airgun array,and carried out a field experiment in the Binchuan Fixed Airgun Signal Transmission station to study the influences of the asynchronous excitation on the source signal.The experimental results show that:the newly developed airgun array firing system can ignite the airguns according to the setting time series with high precision.By designing the excitation time series,the asynchronous excitation can enhance the energy of airgun source signal at 3-5 Hz,and reduce the energy of pressure pulse wave at 6-18 Hz.The signal detection capability of the asynchronous excitation with time series mode is equivalent to the synchronous excitation.
基金supported by the National Key Research and Development Program of China (2021YFA0805300,2021YFA0805200)National Natural Science Foundation of China (32170981,82371874,82394422,82171244,82071421,82271902)+1 种基金Guangzhou Key Research Program on Brain Science (202007030008)Department of Science and Technology of Guangdong Province (2021ZT09Y007,2020B121201006,2018B030337001)。
文摘Huntington'sdisease(HD)isahereditary neurodegenerative disorder for which there is currently no effectivetreatmentavailable.Consequently,the development of appropriate disease models is critical to thoroughly investigate disease progression.The genetic basis of HD involves the abnormal expansion of CAG repeats in the huntingtin(HTT)gene,leading to the expansion of a polyglutamine repeat in the HTT protein.Mutant HTT carrying the expanded polyglutamine repeat undergoes misfolding and forms aggregates in the brain,which precipitate selective neuronal loss in specific brain regions.Animal models play an important role in elucidating the pathogenesis of neurodegenerative disorders such as HD and in identifying potential therapeutic targets.Due to the marked species differences between rodents and larger animals,substantial efforts have been directed toward establishing large animal models for HD research.These models are pivotal for advancing the discovery of novel therapeutic targets,enhancing effective drug delivery methods,and improving treatment outcomes.We have explored the advantages of utilizing large animal models,particularly pigs,in previous reviews.Since then,however,significant progress has been made in developing more sophisticated animal models that faithfully replicate the typical pathology of HD.In the current review,we provide a comprehensive overview of large animal models of HD,incorporating recent findings regarding the establishment of HD knock-in(KI)pigs and their genetic therapy.We also explore the utilization of large animal models in HD research,with a focus on sheep,non-human primates(NHPs),and pigs.Our objective is to provide valuable insights into the application of these large animal models for the investigation and treatment of neurodegenerative disorders.
基金Supported by the National Natural Science Foundation of China(72088101,42372175)PetroChina Science and Technology Innovation Fund Program(2021DQ02-0904)。
文摘This article elucidates the concept of large model technology,summarizes the research status of large model technology both domestically and internationally,provides an overview of the application status of large models in vertical industries,outlines the challenges and issues confronted in applying large models in the oil and gas sector,and offers prospects for the application of large models in the oil and gas industry.The existing large models can be briefly divided into three categories:large language models,visual large models,and multimodal large models.The application of large models in the oil and gas industry is still in its infancy.Based on open-source large language models,some oil and gas enterprises have released large language model products using methods like fine-tuning and retrieval augmented generation.Scholars have attempted to develop scenario-specific models for oil and gas operations by using visual/multimodal foundation models.A few researchers have constructed pre-trained foundation models for seismic data processing and interpretation,as well as core analysis.The application of large models in the oil and gas industry faces challenges such as current data quantity and quality being difficult to support the training of large models,high research and development costs,and poor algorithm autonomy and control.The application of large models should be guided by the needs of oil and gas business,taking the application of large models as an opportunity to improve data lifecycle management,enhance data governance capabilities,promote the construction of computing power,strengthen the construction of“artificial intelligence+energy”composite teams,and boost the autonomy and control of large model technology.
基金the National Key R&D Program of China(Grant No.2021YFC3000802)the National Natural Science Foundation of China(Grant No.42175165)the National Key Scientific and Technological Infrastructure project“Earth System Numerical Simulation Facility”(EarthLab).
文摘Shallow convection plays an important role in transporting heat and moisture from the near-surface to higher altitudes,yet its parameterization in numerical models remains a great challenge,partly due to the lack of high-resolution observations.This study describes a large eddy simulation(LES)dataset for four shallow convection cases that differ primarily in inversion strength,which can be used as a surrogate for real data.To reduce the uncertainty in LES modeling,three different large eddy models were used,including SAM(System for Atmospheric Modeling),WRF(Weather Research and Forecasting model),and UCLA-LES.Results show that the different models generally exhibit similar behavior for each shallow convection case,despite some differences in the details of the convective structure.In addition to grid-averaged fields,conditionally sampled variables,such as in-cloud moisture and vertical velocity,are also provided,which are indispensable for calculation of the entrainment/detrainment rate.Considering the essentiality of the entraining/detraining process in the parameterization of cumulus convection,the dataset presented in this study is potentially useful for validation and improvement of the parameterization of shallow convection.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.52179076,51979186).
文摘As one of the most common river patterns in nature,meandering river has very complex flow structures in its curved channel bends,including secondary flow structure and primary flow velocity redistributions.To date,most of the studies have been carried out on the flow structures in channel bends with unavoidable influences from inlet and outlet boundaries,while a streamwise periodic boundary can overcome this shortcoming elegantly.In this paper,large eddy simulations(LES)are employed to investigate the complex flow structures in periodically continuous sharp sine-generated bends.The influence of width-to-depth ratios and dimensionless curvature radiuses are studied.The results highlight two additional vortex structures beyond the commonly known secondary currents:The recirculation zone(RZ)and the inner bank cell(IBC).The width-to-depth ratio shows the determining effect on the recirculation zone.The size of recirculation zone is usually bigger in sine-generated-curve(SGC)channel with large width-to-depth ratios.The biggest recirculation zones appear between the zero-curvature section and the apex section.The inner bank cell only forms in SGC channels with small width-to-depth ratios and low curvature.For SGC channel with large width-to-depth ratios,only one circulation cell is observed near the inner bank.The spatial variations of turbulent features are also revealed by statistical analysis based on the LES sampling data.Results highlight remarkable effect of width-to-depth ratio and dimensionless curvature radius on the turbulent kinetic energy(TKE)and bed shear stress in SGC channels.
基金Supported by National Natural Science Foundation of China(Grant No.52005371)Shanghai Pujiang Program of China(Grant No.2020PJD071)+1 种基金Shanghai Municipal Natural Science Foundation of China(Grant No.22ZR1463900)Fundamental Research Funds for the Central Universities of China.
文摘There are lots of researches on fixture layout optimization for large thin-walled parts.Current researches focus on the positioning problem,i.e.,optimizing the positions of a constant number of fixtures.However,how to determine the number of fixtures is ignored.In most cases,the number of fixtures located on large thin-walled parts is determined based on engineering experience,which leads to huge fixture number and extra waste.Therefore,this paper constructs an optimization model to minimize the number of fixtures.The constraints are set in the optimization model to ensure that the part deformation is within the surface profile tolerance.In addition,the assembly gap between two parts is also controlled.To conduct the optimization,this paper develops an improved particle swarm optimization(IPSO)algorithm by integrating the shrinkage factor and adaptive inertia weight.In the algorithm,particles are encoded according to the fixture position.Each dimension of the particle is assigned to a sub-region by constraining the optional position range of each fixture to improve the optimization efficiency.Finally,a case study on ship curved panel assembly is provided to prove that our method can optimize the number of fixtures while meeting the assembly quality requirements.This research proposes a method to optimize the number of fixtures,which can reduce the number of fixtures and achieve deformation control at the same time.
基金supported by the Key Research Program of Frontier Sciences,Chinese Academy of Sciences(Grant ZDBS-LY-DQC019)the National Key Research and Development Program of China(2023YFE0124300)+4 种基金the National Natural Science Foundation of China(32301344)Major Program of Institute of Applied EcologyChinese Academy of Sciences(IAEMP202201)supported by grants from the U.S.National Science Foundation(DEB 2240431)the Seeding Projects for Enabling Excellence and Distinction(SPEED)Program at Washington University in St.Louis。
文摘Biodiversity,large trees,and environmental conditions such as climate and soil have important effects on forest carbon stocks.However,recent studies in temperate forests suggest that the relative importance of these factors depends on tree mycorrhizal associations,whereby large-tree effects may be driven by ectomycorrhizal(EM)trees,diversity effects may be driven by arbuscular mycorrhizal(AM)trees,and environment effects may depend on differential climate and soil preferences of AM and EM trees.To test this hypothesis,we used forest-inventory data consisting of over 80,000 trees from 631 temperate-forest plots(30 m×30 m)across Northeast China to examine how biodiversity(species diversity and ecological uniqueness),large trees(top 1%of tree diameters),and environmental factors(climate and soil nutrients)differently regulate aboveground carbon stocks of AM trees,EM trees,and AM and EM trees combined(i.e.total aboveground carbon stock).We found that large trees had a positive effect on both AM and EM tree carbon stocks.However,biodiversity and environmental factors had opposite effects on AM vs.EM tree carbon stocks.Specifically,the two components of biodiversity had positive effects on AM tree carbon stocks,but negative effects on EM tree carbon stocks.Environmental heterogeneity(mean annual temperature and soil nutrients)also exhibited contrasting effects on AM and EM tree carbon stocks.Consequently,for the total carbon stock,the positive large-tree effect far surpasses the diversity and environment effect.This is mainly because when integrating AM and EM tree carbon stock into total carbon stock,the opposite diversity-effect(also environment-effect)on AM vs.EM tree carbon stock counteracts each other while the consistent positive large-tree effect on AM and EM tree carbon stock is amplified.In summary,this study emphasized a mycorrhizal viewpoint to better understand the determinants of overarching aboveground carbon profile across regional forests.
基金Project(41941018)supported by the National Natural Science Foundation of China for the Special Project FundingProject(22-JKCF-08)supported by the Study on in-situ Stress Database and 3D in-situ Stress Inversion Technology of Highway Tunnel in Shanxi Province,China+1 种基金Project(2022-JKKJ-6)supported by the Study on Disaster Mechanism and NPR Anchor Cable Prevention and Control of Coal Mining Caving Subsidence in Operating Tunnel in Mountainous Area,ChinaProject(BBJ2024032)supported by the Fundamental Research Funds for the Central Universities(PhD Top Innovative Talents Fund of CUMTB),China。
文摘A study was conducted to analyze the deformation mechanism of strongly weathered quartz schist in the Daliangshan Tunnel,located in the western Transverse Mountain area.A large deformation problem was experienced during the tunnel construction.To mitigate this problem,a support system was designed incorporating negative Poisson ratio(NPR)anchor cables with negative Poisson ratio effect.Physical model experiments,field experiments,and numerical simulation experiments were conducted to investigate the compensation mechanical behavior of NPR anchor cables.The large deformations of soft rocks in the Daliangshan Tunnel are caused by a high ground stress,a high degree of joint fracture development,and a high degree of surrounding rock fragmentation.A compensation mechanics support system combining long and short NPR anchor cables was suggested to provide sufficient counter-support force(approximately 350 kN)for the surrounding rock inside the tunnel.Comparing the NPR anchor cable support system with the original support system used in the Daliangshan tunnel showed that an NPR anchor cable support system,combining cables of 6.3 m and 10.3 m in length,effectively prevented convergence of surrounding rock deformation,and the integrated settlement convergence value remained below 300 mm.This study provides an effective scientific basis for resolving large deformation problems in deeply buried soft rocks in western transverse mountain areas.
基金was performed within the framework of the State Assignment Projects No.0284–2021-0002.
文摘Comprehensive research has been implemented to raise the efficiency of the geochemical survey of stream sediments(SSs)that formed under the cryolithogenesis conditions.The authors analysed the composition,structure and specific features of the formation of exogenous anomalous geochemical fields(AGFs)identified through SSs of large river valleys of IV order.In our case,these were the valleys of Maly Ken,Ken and Tap Rivers.These rivers are located in the central and southern parts of the Balygychan-Sugoy trough enclosed in the Magadan region,North-East of Russia.The authors proposed a new technique to sample loose alluvium of SSs in the large river valleys along the profiles.The profiles were located across the valleys.The AGFs of Au,Ag,Pb,Zn,Sn,Bi,Mo and W were studied.Correlations between elements have been established.These elements are the main indicator elements of Au-Ag,Ag-Pb,Sn-Ag,Mo-W and Sn-W mineralization occurring on the sites under study.The results obtained were compared with the results of geochemical surveys of SSs.It is concluded that the AGFs recognized along the profiles reflect the composition and structure of eroded and drained ore zones,uncover completely and precisely the pattern of element distribution in loose sediments of large water flows.The alluvium fraction<0.25 mm seems to be most significant in a practical sense,as it concentrated numerous ore elements.Sampling of this fraction in the river valleys of IV order does not cause any difficulty,for this kind of material is plentiful.The developed technique of alluvium sampling within large river valleys is efficient in searching for diverse mineralization at all stages of prognostic prospecting.It is applicable for geochemical survey of SSs performed at different scales both in the North-East of Russia,as well as other regions with similar climatic conditions,where the SSs are formed under the cryolithogenesis conditions.
基金financial support from the National Key Research and Development Program of China (No.2023YFC2907501)the National Natural Science Foundation of China (No.52374106)the Fundamental Research Funds for the Central Universities (No.2023ZKPYNY01)。
文摘In order to improve rib stability,failure criteria and instability mode of a thick coal seam with inter-band rock layer are analysed in this study.A three-dimensional mechanical model is established for the rib by considering the rock layer.A safety factor is defined foy the rib,and it is observed that the safety factor exhibits a positive correlation with the thickness and strength of the inter-band rock.A calculation method for determining critical parameters of the rock layer is presented to ensure the rib stability.It is revealed that incomplete propagation of the fracture at the hard rock constitutes a fundamental prerequisite for ensuring the rib stability.The influence of the position of the inter-band rock in the coal seam on failure mechanism of the rib was thoroughly investigated by developing a series of physical models for the rib at the face area.The best position for the inter-band rock in the coal seam is at a height of 1.5 m away from the roof line,which tends to provide a good stability state for the rib.For different inter-band rock positions,two ways of controlling rib by increasing supports stiffness and flexible grouting reinforcement are proposed.
基金supported in part by the National Natural Science Foundation of China(62225306,U2141235,52188102,and 62003145)the National Key Research and Development Program of China(2022ZD0119601)+1 种基金Guangdong Basic and Applied Research Foundation(2022B1515120069)the Science and Technology Project of State Grid Corporation of China(5100-202199557A-0-5-ZN).
文摘Hierarchical networks are frequently encountered in animal groups,gene networks,and artificial engineering systems such as multiple robots,unmanned vehicle systems,smart grids,wind farm networks,and so forth.The structure of a large directed hierarchical network is often strongly influenced by reverse edges from lower-to higher-level nodes,such as lagging birds’howl in a flock or the opinions of lowerlevel individuals feeding back to higher-level ones in a social group.This study reveals that,for most large-scale real hierarchical networks,the majority of the reverse edges do not affect the synchronization process of the entire network;the synchronization process is influenced only by a small part of these reverse edges along specific paths.More surprisingly,a single effective reverse edge can slow down the synchronization of a huge hierarchical network by over 60%.The effect of such edges depends not on the network size but only on the average in-degree of the involved subnetwork.The overwhelming majority of active reverse edges turn out to have some kind of“bunching”effect on the information flows of hierarchical networks,which slows down synchronization processes.This finding refines the current understanding of the role of reverse edges in many natural,social,and engineering hierarchical networks,which might be beneficial for precisely tuning the synchronization rhythms of these networks.Our study also proposes an effective way to attack a hierarchical network by adding a malicious reverse edge to it and provides some guidance for protecting a network by screening out the specific small proportion of vulnerable nodes.
基金Project(202203021221088)supported by the Fundamental Research Program of Shanxi Province,ChinaProject(20230010)supported by the Fund Program for the Scientific Activities of Selected Returned Overseas Professionals in Shanxi Province,China+5 种基金Project(202201050201012)supported by the Shanxi Provincial Science and Technology Major Special Project Plan of Taking the Lead in Unveiling the List,ChinaProject(2023-063)supported by the Research Project Supported by Shanxi Scholarship Council of ChinaProjects(51771129,52271109)supported by the National Natural Science Foundation of ChinaProject(2021YFB3703300)supported by the National Key Research and Development Program for Young Scientists,ChinaProject(YDZJSX2021B019)supported by the Special Fund Project for Guiding Local Science and Technology Development by the Central Government,ChinaProject(SKL-YSJ202103)supported by the Open Foundation of State Key Laboratory of High-end Compressor and System Technology,China。
文摘In this study,the Mg-3Zn-0.5Zr-χNd(χ=0,0.6)alloys were subjected to final rolling treatment with large deformation of 50%.The impact of annealing temperatures on the microstructure and mechanical properties was investigated.The rolled Mg-3Zn-0.5Zr-0.6Nd alloy exhibited an ultimate tensile strength of 386 MPa,a yield strength of 361 MPa,and an elongation of 7.1%.Annealing at different temperatures resulted in reduced strength and obviously increased elongation for both alloys.Optimal mechanical properties for the Mg-3Zn-0.5Zr-0.6Nd alloy were achieved after annealing at 200℃,with an ultimate tensile strength of 287 MPa,a yield strength of 235 MPa,and an elongation of 26.1%.The numerous deformed microstructures,twins,and precipitated phases in the rolled alloy could impede the deformation at room temperature and increase the work hardening rate.After annealing,a decrease in the work hardening effect and an increase in the dynamic recovery effect were obtained due to the formation of fine equiaxed grains,and the increased volume fraction of precipitated phases,which significantly improved the elongation of the alloy.Additionally,the addition of Nd element could enhance the annealing recrystallization rate,reduce the Schmid factor difference between basal and prismatic slip systems,facilitate multi-system slip initiation and improve the alloy plasticity.
基金supported by the National Science and Technology Innovation 2030 Major Projects(2021ZD0202200)National Natural Science Foundation of China(32171090,81970264)+1 种基金Shanghai Science and Technology Commission(21ZR1482600)2023 Youth Innovation Promotion Association CAS。
文摘Most viruses and transposons serve as effective carriers for the introduction of foreign DNA up to 11 kb into vertebrate genomes.However,their activity markedly diminishes with payloads exceeding 11 kb.Expanding the payload capacity of transposons could facilitate more sophisticated cargo designs,improving the regulation of expression and minimizing mutagenic risks associated with molecular therapeutics,metabolic engineering,and transgenic animal production.In this study,we improved the Tol2 transposon by increasing protein expression levels using a translational enhancer(QBI SP163,ST)and enhanced the nuclear targeting ability using the nuclear localization protein H2B(SHT).The modified Tol2 and ST transposon efficiently integrated large DNA cargos into human cell cultures(H1299),comparable to the well-established super PiggyBac system.Furthermore,mRNA from ST and SHT showed a significant increase in transgene delivery efficiency of large DNA payloads(8 kb,14 kb,and 24 kb)into zebrafish(Danio rerio).This study presents a modified Tol2 transposon as an enhanced nonviral vector for the delivery of large DNA payloads in transgenic applications.
基金supported by the foundation of“Cold area new energy service engineering laboratory battery pack comprehensive test system”from Jilin Provincial Development and Reform Commission(2020C021-6)the National Natural Science Foundation of China(NNSFC,No.52371109).
文摘In order to effectively reduce energy consumption and increase range mile,new energy vehicles represented by Tesla have greatly aroused the application of integrated magnesium(Mg)alloy die casting technology in automobiles.Previously,the application of Mg alloys in automobiles,especially in automotive cockpit components,is quite extensive,while it has almost disappeared for a period of time due to its relatively high cost,causing a certain degree of information loss in the application technology of Mg alloy parts in automobiles.The rapid development of automotive technology has led to a higher requirement for the automotive components compared with those traditional one.Therefore,whatever the components themselves,or the Mg alloy materials and die casting process have to face an increasing challenge,needing to be upgraded.In addition,owing to its high integration characteristics,the application of Mg alloy die casting technology in large-sized and thin-walled automotive parts has inherent advantages and needs to be expanded urgently.Indeed,it necessitates exploring advance Mg alloys and new product structures and optimizing die casting processes.This article summarizes and analyzes the development status of thin-walled and large-sized die casting Mg alloy parts in passenger car cockpit and corresponding material selection methods,die casting processes as well as mold design techniques.Furthermore,this work will aid researchers in establishing a comprehensive understanding of the manufacture of thin-walled and large-sized die casting Mg alloy parts in automobile cockpit.It will also assist them in developing new Mg alloys with improved comprehensive performance and new processes to meet the high requirements for die casting automotive components.