Machine learning applications in healthcare clinical practice and research

Machine learning(ML)is a type of artificial intelligence that assists computers in the acquisition of knowledge through data analysis,thus creating machines that can complete tasks otherwise requiring human intelligence.Among its various applications,it has proven groundbreaking in healthcare as well,both in clinical practice and research.In this editorial,we succinctly introduce ML applications and present a study,featured in the latest issue of the World Journal of Clinical Cases.The authors of this study conducted an analysis using both multiple linear regression(MLR)and ML methods to investigate the significant factors that may impact the estimated glomerular filtration rate in healthy women with and without non-alcoholic fatty liver disease(NAFLD).Their results implicated age as the most important determining factor in both groups,followed by lactic dehydrogenase,uric acid,forced expiratory volume in one second,and albumin.In addition,for the NAFLD-group,the 5th and 6th most important impact factors were thyroid-stimulating hormone and systolic blood pressure,as compared to plasma calcium and body fat for the NAFLD+group.However,the study's distinctive contribution lies in its adoption of ML methodologies,showcasing their superiority over traditional statistical approaches(herein MLR),thereby highlighting the potential of ML to represent an invaluable advanced adjunct tool in clinical practice and research.

Effects of Health Education with Problem-Based Learning Approaches on the Knowledge, Attitude, Practice and Coping Skills of Women with High-Risk Pregnancies in Plateau Areas

Objective: Given the unique cultural background, way of life, and physical environment of the Tibetan Plateau, this study aims to investigate the effects of health education using problem-based learning (PBL) approaches on the knowledge, attitude, practice, and coping skills of women with high-risk pregnancies in this region. Methods: 76 high-risk pregnancy cases were enrolled at Tibet’s Linzhi People’s Hospital between September 2023 and April 2024. 30 patients admitted between September 2023 and December 2023 were selected as the control group and were performed with regular patient education. 46 patients admitted between January 2024 and April 2024 were selected as the observation group and were performed regular patient education with problem-based learning approaches. Two groups’ performance on their health knowledge, attitude, practice and coping skills before and after interventions were evaluated, and patient satisfaction were measured at the end of the study. Results: There was no statistical significance (P P P Conclusions: Health education with problem-based learning approaches is worth promoting as it can help high-risk pregnant women in plateau areas develop better health knowledge, attitude and practice and healthier coping skills. Also, it can improve patient sanctification.

A Tutorial on Federated Learning from Theory to Practice:Foundations,Software Frameworks,Exemplary Use Cases,and Selected Trends

When data privacy is imposed as a necessity,Federated learning(FL)emerges as a relevant artificial intelligence field for developing machine learning(ML)models in a distributed and decentralized environment.FL allows ML models to be trained on local devices without any need for centralized data transfer,thereby reducing both the exposure of sensitive data and the possibility of data interception by malicious third parties.This paradigm has gained momentum in the last few years,spurred by the plethora of real-world applications that have leveraged its ability to improve the efficiency of distributed learning and to accommodate numerous participants with their data sources.By virtue of FL,models can be learned from all such distributed data sources while preserving data privacy.The aim of this paper is to provide a practical tutorial on FL,including a short methodology and a systematic analysis of existing software frameworks.Furthermore,our tutorial provides exemplary cases of study from three complementary perspectives:i)Foundations of FL,describing the main components of FL,from key elements to FL categories;ii)Implementation guidelines and exemplary cases of study,by systematically examining the functionalities provided by existing software frameworks for FL deployment,devising a methodology to design a FL scenario,and providing exemplary cases of study with source code for different ML approaches;and iii)Trends,shortly reviewing a non-exhaustive list of research directions that are under active investigation in the current FL landscape.The ultimate purpose of this work is to establish itself as a referential work for researchers,developers,and data scientists willing to explore the capabilities of FL in practical applications.

Advancing automated pupillometry:a practical deep learning model utilizing infrared pupil images

AIM:To establish pupil diameter measurement algorithms based on infrared images that can be used in real-world clinical settings.METHODS:A total of 188 patients from outpatient clinic at He Eye Specialist Shenyang Hospital from Spetember to December 2022 were included,and 13470 infrared pupil images were collected for the study.All infrared images for pupil segmentation were labeled using the Labelme software.The computation of pupil diameter is divided into four steps:image pre-processing,pupil identification and localization,pupil segmentation,and diameter calculation.Two major models are used in the computation process:the modified YoloV3 and Deeplabv 3+models,which must be trained beforehand.RESULTS:The test dataset included 1348 infrared pupil images.On the test dataset,the modified YoloV3 model had a detection rate of 99.98% and an average precision(AP)of 0.80 for pupils.The DeeplabV3+model achieved a background intersection over union(IOU)of 99.23%,a pupil IOU of 93.81%,and a mean IOU of 96.52%.The pupil diameters in the test dataset ranged from 20 to 56 pixels,with a mean of 36.06±6.85 pixels.The absolute error in pupil diameters between predicted and actual values ranged from 0 to 7 pixels,with a mean absolute error(MAE)of 1.06±0.96 pixels.CONCLUSION:This study successfully demonstrates a robust infrared image-based pupil diameter measurement algorithm,proven to be highly accurate and reliable for clinical application.

PEPFL:A framework for a practical and efficient privacy-preserving federated learning

As an emerging joint learning model,federated learning is a promising way to combine model parameters of different users for training and inference without collecting users’original data.However,a practical and efficient solution has not been established in previous work due to the absence of efficient matrix computation and cryptography schemes in the privacy-preserving federated learning model,especially in partially homomorphic cryptosystems.In this paper,we propose a Practical and Efficient Privacy-preserving Federated Learning(PEPFL)framework.First,we present a lifted distributed ElGamal cryptosystem for federated learning,which can solve the multi-key problem in federated learning.Secondly,we develop a Practical Partially Single Instruction Multiple Data(PSIMD)parallelism scheme that can encode a plaintext matrix into single plaintext for encryption,improving the encryption efficiency and reducing the communication cost in partially homomorphic cryptosystem.In addition,based on the Convolutional Neural Network(CNN)and the designed cryptosystem,a novel privacy-preserving federated learning framework is designed by using Momentum Gradient Descent(MGD).Finally,we evaluate the security and performance of PEPFL.The experiment results demonstrate that the scheme is practicable,effective,and secure with low communication and computation costs.

Innovation and Practice of Teaching Methods in Digital and Adaptive Learning:Taking Communication Engineering Major as an Example

This paper proposes teaching reforms in communication engineering majors,emphasizing the implementation of digital and adaptive teaching methodologies,integrating emerging technologies,breaking free from the constraints of traditional education,and fostering high-caliber talents.The reform measures encompass fundamental data collection,recognition of individual characteristics,recommendation of adaptive learning resources,process-oriented teaching management,adaptive student guidance and early warning systems,personalized evaluation,and the construction of an integrated service platform.These measures,when combined,form a comprehensive system that is expected to enhance teaching quality and efficiency,and facilitate student development.

基于改进Q-Learning的移动机器人路径规划算法

随着移动机器人在生产生活中的深入应用,其路径规划能力也需要向快速性和环境适应性兼备发展。为解决现有移动机器人使用强化学习方法进行路径规划时存在的探索前期容易陷入局部最优、反复搜索同一区域,探索后期收敛率低、收敛速度慢的问题,本研究提出一种改进的Q-Learning算法。该算法改进Q矩阵赋值方法,使迭代前期探索过程具有指向性,并降低碰撞的情况;改进Q矩阵迭代方法,使Q矩阵更新具有前瞻性,避免在一个小区域中反复探索;改进随机探索策略,在迭代前期全面利用环境信息,后期向目标点靠近。在不同栅格地图仿真验证结果表明,本文算法在Q-Learning算法的基础上,通过上述改进降低探索过程中的路径长度、减少抖动并提高收敛的速度,具有更高的计算效率。

M-learning结合CBL在消化科规培教学中的探讨及应用

目的探究移动学习平台(M-learning,ML)结合案例教学(Case-based Learning,CBL)在消化科住院医师规范化培训(简称规培)教学中的应用效果。方法选取2021年1月—2023年1月于上海市徐汇区中心医院消化科参加规培学习的80名医师作为研究对象,将其按照随机数表法分为研究组和对照组,每组40名。对照组给予传统讲授式教学法,研究组给予M-learning结合CBL教学法,对比两组医师的理论考试成绩、实践技能考试成绩和学习满意度。结果研究组的理论成绩和实践技能考试成绩均高于对照组,差异具有统计学意义(P均<0.05);研究组的学习满意度明显高于对照组,差异具有统计学意义(P<0.05)。结论将Mlearning结合CBL教学法应用于消化科规培教学中,不仅能够提升医师的理论考试成绩和实践技能考试成绩,还能够有效提高医师学习满意度。

基于Q-Learning的航空器滑行路径规划研究

针对传统算法规划航空器滑行路径准确度低、不能根据整体场面运行情况进行路径规划的问题,提出一种基于Q-Learning的路径规划方法。通过对机场飞行区网络结构模型和强化学习的仿真环境分析,设置了状态空间和动作空间,并根据路径的合规性和合理性设定了奖励函数,将路径合理性评价值设置为滑行路径长度与飞行区平均滑行时间乘积的倒数。最后,分析了动作选择策略参数对路径规划模型的影响。结果表明,与A*算法和Floyd算法相比,基于Q-Learning的路径规划在滑行距离最短的同时,避开了相对繁忙的区域,路径合理性评价值高。

Machine learning applications in stroke medicine:advancements,challenges,and future prospectives

Stroke is a leading cause of disability and mortality worldwide,necessitating the development of advanced technologies to improve its diagnosis,treatment,and patient outcomes.In recent years,machine learning techniques have emerged as promising tools in stroke medicine,enabling efficient analysis of large-scale datasets and facilitating personalized and precision medicine approaches.This abstract provides a comprehensive overview of machine learning’s applications,challenges,and future directions in stroke medicine.Recently introduced machine learning algorithms have been extensively employed in all the fields of stroke medicine.Machine learning models have demonstrated remarkable accuracy in imaging analysis,diagnosing stroke subtypes,risk stratifications,guiding medical treatment,and predicting patient prognosis.Despite the tremendous potential of machine learning in stroke medicine,several challenges must be addressed.These include the need for standardized and interoperable data collection,robust model validation and generalization,and the ethical considerations surrounding privacy and bias.In addition,integrating machine learning models into clinical workflows and establishing regulatory frameworks are critical for ensuring their widespread adoption and impact in routine stroke care.Machine learning promises to revolutionize stroke medicine by enabling precise diagnosis,tailored treatment selection,and improved prognostication.Continued research and collaboration among clinicians,researchers,and technologists are essential for overcoming challenges and realizing the full potential of machine learning in stroke care,ultimately leading to enhanced patient outcomes and quality of life.This review aims to summarize all the current implications of machine learning in stroke diagnosis,treatment,and prognostic evaluation.At the same time,another purpose of this paper is to explore all the future perspectives these techniques can provide in combating this disabling disease.

改进Q-Learning的路径规划算法研究

针对Q-Learning算法学习效率低、收敛速度慢且在动态障碍物的环境下路径规划效果不佳的问题,本文提出一种改进Q-Learning的移动机器人路径规划算法.针对该问题,算法根据概率的突变性引入探索因子来平衡探索和利用以加快学习效率;通过在更新函数中设计深度学习因子以保证算法探索概率;融合遗传算法,避免陷入局部路径最优同时按阶段探索最优迭代步长次数,以减少动态地图探索重复率;最后提取输出的最优路径关键节点采用贝塞尔曲线进行平滑处理,进一步保证路径平滑度和可行性.实验通过栅格法构建地图,对比实验结果表明,改进后的算法效率相较于传统算法在迭代次数和路径上均有较大优化,且能够较好的实现动态地图下的路径规划,进一步验证所提方法的有效性和实用性.

基于Q-learning的自适应链路状态路由协议

针对大规模无人机自组网面临的任务需求多样性、电磁环境复杂性、节点高机动性等问题,充分考虑无人机节点高速移动的特点,基于无人机拓扑稳定度和链路通信容量指标设计了一种无人机多点中继(multi-point relay,MPR)选择方法;为了减少网络路由更新时间,增加无人机自组网路由策略的稳定性和可靠性,提出了一种基于Q-learning的自适应链路状态路由协议(Q-learning based adaptive link state routing,QALSR)。仿真结果表明,所提算法性能指标优于现有的主动路由协议。

Significant risk factors for intensive care unit-acquired weakness:A processing strategy based on repeated machine learning

BACKGROUND Intensive care unit-acquired weakness(ICU-AW)is a common complication that significantly impacts the patient's recovery process,even leading to adverse outcomes.Currently,there is a lack of effective preventive measures.AIM To identify significant risk factors for ICU-AW through iterative machine learning techniques and offer recommendations for its prevention and treatment.METHODS Patients were categorized into ICU-AW and non-ICU-AW groups on the 14th day post-ICU admission.Relevant data from the initial 14 d of ICU stay,such as age,comorbidities,sedative dosage,vasopressor dosage,duration of mechanical ventilation,length of ICU stay,and rehabilitation therapy,were gathered.The relationships between these variables and ICU-AW were examined.Utilizing iterative machine learning techniques,a multilayer perceptron neural network model was developed,and its predictive performance for ICU-AW was assessed using the receiver operating characteristic curve.RESULTS Within the ICU-AW group,age,duration of mechanical ventilation,lorazepam dosage,adrenaline dosage,and length of ICU stay were significantly higher than in the non-ICU-AW group.Additionally,sepsis,multiple organ dysfunction syndrome,hypoalbuminemia,acute heart failure,respiratory failure,acute kidney injury,anemia,stress-related gastrointestinal bleeding,shock,hypertension,coronary artery disease,malignant tumors,and rehabilitation therapy ratios were significantly higher in the ICU-AW group,demonstrating statistical significance.The most influential factors contributing to ICU-AW were identified as the length of ICU stay(100.0%)and the duration of mechanical ventilation(54.9%).The neural network model predicted ICU-AW with an area under the curve of 0.941,sensitivity of 92.2%,and specificity of 82.7%.CONCLUSION The main factors influencing ICU-AW are the length of ICU stay and the duration of mechanical ventilation.A primary preventive strategy,when feasible,involves minimizing both ICU stay and mechanical ventilation duration.

Machine learning for predicting the outcome of terminal ballistics events

Machine learning(ML) is well suited for the prediction of high-complexity,high-dimensional problems such as those encountered in terminal ballistics.We evaluate the performance of four popular ML-based regression models,extreme gradient boosting(XGBoost),artificial neural network(ANN),support vector regression(SVR),and Gaussian process regression(GP),on two common terminal ballistics’ problems:(a)predicting the V50ballistic limit of monolithic metallic armour impacted by small and medium calibre projectiles and fragments,and(b) predicting the depth to which a projectile will penetrate a target of semi-infinite thickness.To achieve this we utilise two datasets,each consisting of approximately 1000samples,collated from public release sources.We demonstrate that all four model types provide similarly excellent agreement when interpolating within the training data and diverge when extrapolating outside this range.Although extrapolation is not advisable for ML-based regression models,for applications such as lethality/survivability analysis,such capability is required.To circumvent this,we implement expert knowledge and physics-based models via enforced monotonicity,as a Gaussian prior mean,and through a modified loss function.The physics-informed models demonstrate improved performance over both classical physics-based models and the basic ML regression models,providing an ability to accurately fit experimental data when it is available and then revert to the physics-based model when not.The resulting models demonstrate high levels of predictive accuracy over a very wide range of projectile types,target materials and thicknesses,and impact conditions significantly more diverse than that achievable from any existing analytical approach.Compared with numerical analysis tools such as finite element solvers the ML models run orders of magnitude faster.We provide some general guidelines throughout for the development,application,and reporting of ML models in terminal ballistics problems.

A credibility-aware swarm-federated deep learning framework in internet of vehicles

Although Federated Deep Learning(FDL)enables distributed machine learning in the Internet of Vehicles(IoV),it requires multiple clients to upload model parameters,thus still existing unavoidable communication overhead and data privacy risks.The recently proposed Swarm Learning(SL)provides a decentralized machine learning approach for unit edge computing and blockchain-based coordination.A Swarm-Federated Deep Learning framework in the IoV system(IoV-SFDL)that integrates SL into the FDL framework is proposed in this paper.The IoV-SFDL organizes vehicles to generate local SL models with adjacent vehicles based on the blockchain empowered SL,then aggregates the global FDL model among different SL groups with a credibility weights prediction algorithm.Extensive experimental results show that compared with the baseline frameworks,the proposed IoV-SFDL framework reduces the overhead of client-to-server communication by 16.72%,while the model performance improves by about 5.02%for the same training iterations.

Artificial Intelligence Meets Flexible Sensors:Emerging Smart Flexible Sensing Systems Driven by Machine Learning and Artificial Synapses

The recent wave of the artificial intelligence(AI)revolution has aroused unprecedented interest in the intelligentialize of human society.As an essential component that bridges the physical world and digital signals,flexible sensors are evolving from a single sensing element to a smarter system,which is capable of highly efficient acquisition,analysis,and even perception of vast,multifaceted data.While challenging from a manual perspective,the development of intelligent flexible sensing has been remarkably facilitated owing to the rapid advances of brain-inspired AI innovations from both the algorithm(machine learning)and the framework(artificial synapses)level.This review presents the recent progress of the emerging AI-driven,intelligent flexible sensing systems.The basic concept of machine learning and artificial synapses are introduced.The new enabling features induced by the fusion of AI and flexible sensing are comprehensively reviewed,which significantly advances the applications such as flexible sensory systems,soft/humanoid robotics,and human activity monitoring.As two of the most profound innovations in the twenty-first century,the deep incorporation of flexible sensing and AI technology holds tremendous potential for creating a smarter world for human beings.

Assessments of Data-Driven Deep Learning Models on One-Month Predictions of Pan-Arctic Sea Ice Thickness

In recent years,deep learning methods have gradually been applied to prediction tasks related to Arctic sea ice concentration,but relatively little research has been conducted for larger spatial and temporal scales,mainly due to the limited time coverage of observations and reanalysis data.Meanwhile,deep learning predictions of sea ice thickness(SIT)have yet to receive ample attention.In this study,two data-driven deep learning(DL)models are built based on the ConvLSTM and fully convolutional U-net(FC-Unet)algorithms and trained using CMIP6 historical simulations for transfer learning and fine-tuned using reanalysis/observations.These models enable monthly predictions of Arctic SIT without considering the complex physical processes involved.Through comprehensive assessments of prediction skills by season and region,the results suggest that using a broader set of CMIP6 data for transfer learning,as well as incorporating multiple climate variables as predictors,contribute to better prediction results,although both DL models can effectively predict the spatiotemporal features of SIT anomalies.Regarding the predicted SIT anomalies of the FC-Unet model,the spatial correlations with reanalysis reach an average level of 89%over all months,while the temporal anomaly correlation coefficients are close to unity in most cases.The models also demonstrate robust performances in predicting SIT and SIE during extreme events.The effectiveness and reliability of the proposed deep transfer learning models in predicting Arctic SIT can facilitate more accurate pan-Arctic predictions,aiding climate change research and real-time business applications.

改进的Q-learning蜂群算法求解置换流水车间调度问题

针对置换流水车间调度问题,提出了一种基于改进的Q-learning算法的人工蜂群算法。该算法设计了一种改进的奖励函数作为人工蜂群算法的环境,根据奖励函数的优劣来判断下一代种群的寻优策略,并通过Q-learning智能选择人工蜂群算法的蜜源的更新维度数大小,根据选择的维度数大小对编码进行更新,提高了收敛速度和精度,最后使用不同规模的置换流水车间调度问题的实例来验证所提算法的性能,通过对标准实例的计算与其它算法对比,证明该算法的准确性。

High-throughput calculations combining machine learning to investigate the corrosion properties of binary Mg alloys

Magnesium(Mg)alloys have shown great prospects as both structural and biomedical materials,while poor corrosion resistance limits their further application.In this work,to avoid the time-consuming and laborious experiment trial,a high-throughput computational strategy based on first-principles calculations is designed for screening corrosion-resistant binary Mg alloy with intermetallics,from both the thermodynamic and kinetic perspectives.The stable binary Mg intermetallics with low equilibrium potential difference with respect to the Mg matrix are firstly identified.Then,the hydrogen adsorption energies on the surfaces of these Mg intermetallics are calculated,and the corrosion exchange current density is further calculated by a hydrogen evolution reaction(HER)kinetic model.Several intermetallics,e.g.Y_(3)Mg,Y_(2)Mg and La_(5)Mg,are identified to be promising intermetallics which might effectively hinder the cathodic HER.Furthermore,machine learning(ML)models are developed to predict Mg intermetallics with proper hydrogen adsorption energy employing work function(W_(f))and weighted first ionization energy(WFIE).The generalization of the ML models is tested on five new binary Mg intermetallics with the average root mean square error(RMSE)of 0.11 eV.This study not only predicts some promising binary Mg intermetallics which may suppress the galvanic corrosion,but also provides a high-throughput screening strategy and ML models for the design of corrosion-resistant alloy,which can be extended to ternary Mg alloys or other alloy systems.

Low-Cost Federated Broad Learning for Privacy-Preserved Knowledge Sharing in the RIS-Aided Internet of Vehicles

High-efficiency and low-cost knowledge sharing can improve the decision-making ability of autonomous vehicles by mining knowledge from the Internet of Vehicles(IoVs).However,it is challenging to ensure high efficiency of local data learning models while preventing privacy leakage in a high mobility environment.In order to protect data privacy and improve data learning efficiency in knowledge sharing,we propose an asynchronous federated broad learning(FBL)framework that integrates broad learning(BL)into federated learning(FL).In FBL,we design a broad fully connected model(BFCM)as a local model for training client data.To enhance the wireless channel quality for knowledge sharing and reduce the communication and computation cost of participating clients,we construct a joint resource allocation and reconfigurable intelligent surface(RIS)configuration optimization framework for FBL.The problem is decoupled into two convex subproblems.Aiming to improve the resource scheduling efficiency in FBL,a double Davidon–Fletcher–Powell(DDFP)algorithm is presented to solve the time slot allocation and RIS configuration problem.Based on the results of resource scheduling,we design a reward-allocation algorithm based on federated incentive learning(FIL)in FBL to compensate clients for their costs.The simulation results show that the proposed FBL framework achieves better performance than the comparison models in terms of efficiency,accuracy,and cost for knowledge sharing in the IoV.