Objective:To study the change of left ventricular ultrasonic functional parameters in patients with ACS during peri-PCI period and their relationship with degree of serum myocardial damage.Methods:A total of 76 cases ...Objective:To study the change of left ventricular ultrasonic functional parameters in patients with ACS during peri-PCI period and their relationship with degree of serum myocardial damage.Methods:A total of 76 cases of ACS patients who were treated in our hospital between June 2012 and January 2016 were selected as research subjects, treatment methods were reviewed and then all patients were divided into observation group (n=57) who underwent PCI treatment and control group (n=19) who conformed to PCI indications but underwent conservative treatment under patients' or families' insistence. Left ventricular ultrasonic functional parameter levels and serum myocardial injury index contents were compared between two groups of patients before and after treatment. Pearson test was used to evaluate the relationship between left ventricular ultrasonic functional parameters and myocardial injury in patients with ACS.Results: Before treatment, differences in left ventricular ultrasonic functional parameter levels as well as serum contents of myocardial enzyme spectrum and myocardial apoptosis indexes were not statistically significant between the two groups of patients. After treatment, left ventricular ultrasonic functional parameters LVEDD and LVESD levels in observation group were lower than those in control group while SV level was higher than that in control group;serum contents of myocardial enzyme spectrum cTnT, LDH, CK-MB and AST were lower than those in control group;serum contents of myocardial apoptosis indexes Fas, Caspase-3 and caspase-12 were lower than those in control group while Bcl-2 content was higher than that in control group. The left ventricular ultrasonic functional parameters in ACS patients were directly correlated with the degree of myocardial injury.Conclusion: PCI treatment of patients with ACS can significantly improve left ventricular function and reduce myocardial injury. After treatment, the left ventricular ultrasonic functional parameters are directly correlated with the degree of myocardial injury.展开更多
Objective: To research the clinical application of two-dimensional speckle tracking imaging (2D-STI) in quantitative assessment of left ventricular function in patients with obstructive sleep apnea-hypopnea syndrome (...Objective: To research the clinical application of two-dimensional speckle tracking imaging (2D-STI) in quantitative assessment of left ventricular function in patients with obstructive sleep apnea-hypopnea syndrome (OSAS). Method: From July 2016 to December 2018, 86 patients with OSAS were selected as OSAS group. According to sleep apnea hypopnea index (AHI), they were divided into mild OSAS group (24 cases), moderate OSAS group (29 cases) and severe OSAS group (33 cases). Another 50 healthy volunteers who underwent physical examination in our hospital during the same period were selected as the control group. The left ventricular function of all patients was quantitatively assessed by 2D-STI. The left ventricular function of all patients was quantitatively assessed by 2D-STI. The results of routine echocardiography and left ventricular global strain parameters of the OSAS group, the control group and the OSAS patients with different severity were compared and analyzed. Result: There were no significant differences in the levels of left ventricular ejection fraction (LVEF), left ventricular end diastolic diameter (LVEDd), left ventricular end systolic diameter (LVESd) between the two groups and OSAS patients with different severity (P>0.05). The levels of IVST, LVPW and LVMI in the OSAS group were significantly higher than those in the control group, the levels of end-diastolic interventricular septal thickness (IVS), left ventricular posterior wall thickness (LVPW), left ventricular mass index (LVMI) in the severe OSAS group were significantly higher than those in the mild and moderate OSAS group, and the levels of IVST, LVPW and LVMI in the moderate OSAS group were significantly higher than those in the mild OSAS group, there were significant differences between groups (P<0.05). The levels of GLS, GRS and GCS in the OSAS group were significantly lower than those in the control group (P<0.05). GLS, GRS and GCS levels in the severe OSAS group were significantly lower than those in the mild OSAS group and the moderate OSAS group, while the levels of global longitudinal strain (GLS), global radial strain (GRS) and global circumferential strain (GCS) in the moderate OSAS group were significantly lower than those in the mild OSAS group (P<0.05). Conclusion: The left ventricular systolic function of OSAS patients is obviously impaired. Left ventricular function in OSAS patients can be assessed timely and accurately by two-dimensional speckle tracking imaging.展开更多
目的探讨射频消融(RFCA)治疗频发室性早搏后左室功能和结构的变化。方法收集2006年1月—2011年8月成功行射频消融治疗的频发室性早搏病例59例。比较手术前、后NYHA心功能分级及超声心动图LVEF、LVEDD、LVESD、IVSd、LVPWd等参数的变化...目的探讨射频消融(RFCA)治疗频发室性早搏后左室功能和结构的变化。方法收集2006年1月—2011年8月成功行射频消融治疗的频发室性早搏病例59例。比较手术前、后NYHA心功能分级及超声心动图LVEF、LVEDD、LVESD、IVSd、LVPWd等参数的变化。结果与术前比较,成功消融根治室性早搏后,患者胸闷、心悸症状缓解,NYHA心功能分级明显好转(P<0.05),超声心动图各参数均明显缩小(LVEDD 51.2 mm±4.9 mm vs44.3 mm±4.2 mm,P<0.05,LVESD 32.8 mm±5.1 mm vs 27.2 mm±3.5 mm,P<0.05,IVSd 8.9 mm±0.8 nn vs7.5 mm±0.9 mm,P<0.05,LVPWd 8.8 mm±0.9 mm vs 7.5 mm±0.9 mm,P<0.05);LVEF显著提高(0.64±0.12vs 0.71±0.07,P<0.05)。结论 RFCA是改善频发室性早搏患者症状、心脏结构及功能状况的有效方法。展开更多
文摘Objective:To study the change of left ventricular ultrasonic functional parameters in patients with ACS during peri-PCI period and their relationship with degree of serum myocardial damage.Methods:A total of 76 cases of ACS patients who were treated in our hospital between June 2012 and January 2016 were selected as research subjects, treatment methods were reviewed and then all patients were divided into observation group (n=57) who underwent PCI treatment and control group (n=19) who conformed to PCI indications but underwent conservative treatment under patients' or families' insistence. Left ventricular ultrasonic functional parameter levels and serum myocardial injury index contents were compared between two groups of patients before and after treatment. Pearson test was used to evaluate the relationship between left ventricular ultrasonic functional parameters and myocardial injury in patients with ACS.Results: Before treatment, differences in left ventricular ultrasonic functional parameter levels as well as serum contents of myocardial enzyme spectrum and myocardial apoptosis indexes were not statistically significant between the two groups of patients. After treatment, left ventricular ultrasonic functional parameters LVEDD and LVESD levels in observation group were lower than those in control group while SV level was higher than that in control group;serum contents of myocardial enzyme spectrum cTnT, LDH, CK-MB and AST were lower than those in control group;serum contents of myocardial apoptosis indexes Fas, Caspase-3 and caspase-12 were lower than those in control group while Bcl-2 content was higher than that in control group. The left ventricular ultrasonic functional parameters in ACS patients were directly correlated with the degree of myocardial injury.Conclusion: PCI treatment of patients with ACS can significantly improve left ventricular function and reduce myocardial injury. After treatment, the left ventricular ultrasonic functional parameters are directly correlated with the degree of myocardial injury.
文摘Objective: To research the clinical application of two-dimensional speckle tracking imaging (2D-STI) in quantitative assessment of left ventricular function in patients with obstructive sleep apnea-hypopnea syndrome (OSAS). Method: From July 2016 to December 2018, 86 patients with OSAS were selected as OSAS group. According to sleep apnea hypopnea index (AHI), they were divided into mild OSAS group (24 cases), moderate OSAS group (29 cases) and severe OSAS group (33 cases). Another 50 healthy volunteers who underwent physical examination in our hospital during the same period were selected as the control group. The left ventricular function of all patients was quantitatively assessed by 2D-STI. The left ventricular function of all patients was quantitatively assessed by 2D-STI. The results of routine echocardiography and left ventricular global strain parameters of the OSAS group, the control group and the OSAS patients with different severity were compared and analyzed. Result: There were no significant differences in the levels of left ventricular ejection fraction (LVEF), left ventricular end diastolic diameter (LVEDd), left ventricular end systolic diameter (LVESd) between the two groups and OSAS patients with different severity (P>0.05). The levels of IVST, LVPW and LVMI in the OSAS group were significantly higher than those in the control group, the levels of end-diastolic interventricular septal thickness (IVS), left ventricular posterior wall thickness (LVPW), left ventricular mass index (LVMI) in the severe OSAS group were significantly higher than those in the mild and moderate OSAS group, and the levels of IVST, LVPW and LVMI in the moderate OSAS group were significantly higher than those in the mild OSAS group, there were significant differences between groups (P<0.05). The levels of GLS, GRS and GCS in the OSAS group were significantly lower than those in the control group (P<0.05). GLS, GRS and GCS levels in the severe OSAS group were significantly lower than those in the mild OSAS group and the moderate OSAS group, while the levels of global longitudinal strain (GLS), global radial strain (GRS) and global circumferential strain (GCS) in the moderate OSAS group were significantly lower than those in the mild OSAS group (P<0.05). Conclusion: The left ventricular systolic function of OSAS patients is obviously impaired. Left ventricular function in OSAS patients can be assessed timely and accurately by two-dimensional speckle tracking imaging.
文摘目的探讨射频消融(RFCA)治疗频发室性早搏后左室功能和结构的变化。方法收集2006年1月—2011年8月成功行射频消融治疗的频发室性早搏病例59例。比较手术前、后NYHA心功能分级及超声心动图LVEF、LVEDD、LVESD、IVSd、LVPWd等参数的变化。结果与术前比较,成功消融根治室性早搏后,患者胸闷、心悸症状缓解,NYHA心功能分级明显好转(P<0.05),超声心动图各参数均明显缩小(LVEDD 51.2 mm±4.9 mm vs44.3 mm±4.2 mm,P<0.05,LVESD 32.8 mm±5.1 mm vs 27.2 mm±3.5 mm,P<0.05,IVSd 8.9 mm±0.8 nn vs7.5 mm±0.9 mm,P<0.05,LVPWd 8.8 mm±0.9 mm vs 7.5 mm±0.9 mm,P<0.05);LVEF显著提高(0.64±0.12vs 0.71±0.07,P<0.05)。结论 RFCA是改善频发室性早搏患者症状、心脏结构及功能状况的有效方法。
