Background Previous studies have shown that an echocardiographic right/left ventricular end-diastolic diameter ratio(RV/LV ratio)≥0.9 is an independent predictor of poor prognosis in patients with acute pulmonary emb...Background Previous studies have shown that an echocardiographic right/left ventricular end-diastolic diameter ratio(RV/LV ratio)≥0.9 is an independent predictor of poor prognosis in patients with acute pulmonary embolism. The prognostic value of the RV/LV ratio in patients with idiopathic pulmonary arterial hypertension(IPAH) is still unknown. Methods We retrospectively enrolled 95 consecutive patients with newly diagnosed IPAH and 16 of them were reevaluated by echocardiography at 3-12 months following targeted therapy.Follow-up data were obtained by telephone interviews and review of the patients’ records.Results The RV/LV ratio was in parallel with the severity of World Health Orgnization(WHO) functional class and mean right atrial pressure.The RV/LV ratio was positively correlated with total pulmonary resistance(P P P 2 saturation(P P = 0.001),weight and absence of targeted therapy were independent predictors of death.No significant changes in the RV/LV ratio before and after targeted therapy were observed. A baseline RV/LV ratio≥0.84 or a further increase in the RV/LV ratio during targeted therapy indicated a poor prognosis. Conclusions The RV/LV ratio helps to assess the severity of IPAH and serves as an independent predictor of prognosis in patients with IPAH.展开更多
目的分析血清脑钠肽、降钙素原变化与心力衰竭患者纽约心脏病协会(New York Heart Association,NYHA)分级的相关性。方法选取2019年5月—2023年2月云南省玉溪市第二人民医院收治的97例心力衰竭患者为研究对象,所有患者都进行NYHA心功能...目的分析血清脑钠肽、降钙素原变化与心力衰竭患者纽约心脏病协会(New York Heart Association,NYHA)分级的相关性。方法选取2019年5月—2023年2月云南省玉溪市第二人民医院收治的97例心力衰竭患者为研究对象,所有患者都进行NYHA心功能分级后分为3组,心功能Ⅱ级57例(Ⅱ级组),心功能Ⅲ级28例(Ⅲ级组),心功能Ⅳ级12例(Ⅳ级组),检测3组血清脑钠肽、降钙素原含量并进行相关性分析。结果随着NYHA分级的增加,患者的左室射血分数明显降低,左室舒张末期内径明显升高,差异有统计学意义(P均<0.05)。随着NYHA分级的增加,患者的血清脑钠肽、降钙素原含量明显升高,差异有统计学意义(P均<0.05)。Spearman分析显示NYHA分级与血清脑钠肽、降钙素原含量、左室射血分数、左室舒张末期内径存在相关性(r=0.714、0.746、-0.788、0.692,P均<0.05)。结论心力衰竭患者多伴随有血清脑钠肽、降钙素原的高表达,与患者的NYHA分级存在相关性,可作为判断患者病情的重要依据。展开更多
目的探讨右心室舒张末期内径(RVED)与左心室舒张末期内径(LVED)的比值(RVED/LVED)对肺栓塞的诊断价值。方法回顾性分析深圳大学第一附属医院于2016年6月至2019年6月疑似肺栓塞并行CT肺动脉造影(CTPA)患者120例,将60例肺栓塞患者纳入肺...目的探讨右心室舒张末期内径(RVED)与左心室舒张末期内径(LVED)的比值(RVED/LVED)对肺栓塞的诊断价值。方法回顾性分析深圳大学第一附属医院于2016年6月至2019年6月疑似肺栓塞并行CT肺动脉造影(CTPA)患者120例,将60例肺栓塞患者纳入肺栓塞组,60例非肺栓塞患者为对照组。根据RVED/LVED由小到大分为3组(Tertile 1组:RVED/LVED<0.48、Tertile 2组:RVED/LVED:0.48~0.55、Tertile 3组:RVED/LVED≥0.56)。对3组肺栓塞发生率进行趋势性检验分析,应用多因素Logistic回归分析建立RVED/LVED预测肺栓塞的回归模型,通过受试者工作特征曲线分析预测模型对肺栓塞的诊断效能。结果肺栓塞组的RVED/LVED高于对照组(0.55±0.08 vs.0.50±0.06,P<0.001)。Tertile1组、Tertile2组、Tertile3组肺栓塞的发生率呈递增趋势(分别为30.8%、51.2%、67.5%,P for trend=0.001)。RVED/LVED为预测肺栓塞的独立影响因素,对比Tertle1组,Tertle2组与Tertle3组发生肺栓塞的风险比分别为3.690~5.216(P均<0.05)和5.673~9.627(P均<0.05),并呈趋势性增加(P for trend<0.05)。RVED/LVED与D-二聚体诊断肺栓塞的曲线下面积(AUC)分别为0.702、0.708,含RVED/LVED肺栓塞诊断模型可增加AUC 0.034(P=0.04)。结论RVED/LVED对肺栓塞的诊断具有一定的临床价值,结合危险因素及临床指标建立模型对肺栓塞的诊断效能更高。展开更多
BACKGROUND Coronary heart disease(CHD)causes many adverse cardiovascular events and poses a threat to the patient’s health and quality of life.AIM To evaluate ultrasonography for evaluation of cardiac function and le...BACKGROUND Coronary heart disease(CHD)causes many adverse cardiovascular events and poses a threat to the patient’s health and quality of life.AIM To evaluate ultrasonography for evaluation of cardiac function and lesion degree in patients with CHD.METHODS A total of 106 patients with CHD(study group)and 106 healthy individuals(control group)in our hospital from March 2019 to September 2020 were selected for this study.All subjects were examined by ultrasound,and the mitral orifice’s early-to-late diastolic blood flow velocity ratio(E/A),left ventricular end-diastolic volume(LVDd),and left atrial diameter(LAD)were measured.Values were compared between the study group and healthy group,and the correlation between the ultrasonic parameters of patients with different cardiac function grades and the degree of CHD were assessed.In addition,the ultrasonic parameters of patients with different prognoses were compared after a follow-up for 6 mo.RESULTS E/A(1.46±0.34)of the study group was smaller than that of the control group(1.88±0.44),while LVDd(58.24±5.05 mm)and LAD(43.31±4.38 mm)were larger(48.15±3.93 and 34.94±2.81,respectively;P<0.05).E/A for patients with grade III disease(1.41±0.43)was smaller and their LVDd(60.04±4.21 mm)and LA(44.16±2.79 mm)were larger than those in patients with grade II disease(1.71±0.48,52.18±3.67 mm,and 39.68±2.37,respectively;P<0.05).Patients with grade IV disease had smaller E/A(1.08±0.39)and larger LVDd(66.81±5.39 mm)and LAD(48.81±3.95 mm)than patients with grade II and III disease(P<0.05).In patients with moderate disease,E/A(1.44±0.41)was smaller and LVDd(59.95±4.14 mm)and LAD(45.15±2.97 mm)were larger than in patients with mild disease(1.69±0.50,51.97±3.88 and 38.81±2.56 mm,respectively;P<0.05).In patients with severe disease,E/A(1.13±0.36)was smaller and LVDd(67.70±6.11 mm)and LAD(49.09±4.05 mm)were larger than in patients with moderate disease(P<0.05).E/A was negatively correlated with cardiac function classi-fication and disease severity,while LVDd and LAD were positively correlated with cardiac function classification and disease severity(P<0.05).E/A(1.83±0.51)for patients with good prognosis was higher than that for those with poor prognosis(1.39±0.32),while LVDd(49.60±4.39 mm)and LAD(36.13±3.05 mm)were lower(P<0.05).CONCLUSION The ultrasonic parameters of patients with CHD are abnormal,and differ significantly in patients with different cardiac function grades,lesion degree,and prognosis.展开更多
文摘Background Previous studies have shown that an echocardiographic right/left ventricular end-diastolic diameter ratio(RV/LV ratio)≥0.9 is an independent predictor of poor prognosis in patients with acute pulmonary embolism. The prognostic value of the RV/LV ratio in patients with idiopathic pulmonary arterial hypertension(IPAH) is still unknown. Methods We retrospectively enrolled 95 consecutive patients with newly diagnosed IPAH and 16 of them were reevaluated by echocardiography at 3-12 months following targeted therapy.Follow-up data were obtained by telephone interviews and review of the patients’ records.Results The RV/LV ratio was in parallel with the severity of World Health Orgnization(WHO) functional class and mean right atrial pressure.The RV/LV ratio was positively correlated with total pulmonary resistance(P P P 2 saturation(P P = 0.001),weight and absence of targeted therapy were independent predictors of death.No significant changes in the RV/LV ratio before and after targeted therapy were observed. A baseline RV/LV ratio≥0.84 or a further increase in the RV/LV ratio during targeted therapy indicated a poor prognosis. Conclusions The RV/LV ratio helps to assess the severity of IPAH and serves as an independent predictor of prognosis in patients with IPAH.
文摘目的分析血清脑钠肽、降钙素原变化与心力衰竭患者纽约心脏病协会(New York Heart Association,NYHA)分级的相关性。方法选取2019年5月—2023年2月云南省玉溪市第二人民医院收治的97例心力衰竭患者为研究对象,所有患者都进行NYHA心功能分级后分为3组,心功能Ⅱ级57例(Ⅱ级组),心功能Ⅲ级28例(Ⅲ级组),心功能Ⅳ级12例(Ⅳ级组),检测3组血清脑钠肽、降钙素原含量并进行相关性分析。结果随着NYHA分级的增加,患者的左室射血分数明显降低,左室舒张末期内径明显升高,差异有统计学意义(P均<0.05)。随着NYHA分级的增加,患者的血清脑钠肽、降钙素原含量明显升高,差异有统计学意义(P均<0.05)。Spearman分析显示NYHA分级与血清脑钠肽、降钙素原含量、左室射血分数、左室舒张末期内径存在相关性(r=0.714、0.746、-0.788、0.692,P均<0.05)。结论心力衰竭患者多伴随有血清脑钠肽、降钙素原的高表达,与患者的NYHA分级存在相关性,可作为判断患者病情的重要依据。
文摘目的探讨右心室舒张末期内径(RVED)与左心室舒张末期内径(LVED)的比值(RVED/LVED)对肺栓塞的诊断价值。方法回顾性分析深圳大学第一附属医院于2016年6月至2019年6月疑似肺栓塞并行CT肺动脉造影(CTPA)患者120例,将60例肺栓塞患者纳入肺栓塞组,60例非肺栓塞患者为对照组。根据RVED/LVED由小到大分为3组(Tertile 1组:RVED/LVED<0.48、Tertile 2组:RVED/LVED:0.48~0.55、Tertile 3组:RVED/LVED≥0.56)。对3组肺栓塞发生率进行趋势性检验分析,应用多因素Logistic回归分析建立RVED/LVED预测肺栓塞的回归模型,通过受试者工作特征曲线分析预测模型对肺栓塞的诊断效能。结果肺栓塞组的RVED/LVED高于对照组(0.55±0.08 vs.0.50±0.06,P<0.001)。Tertile1组、Tertile2组、Tertile3组肺栓塞的发生率呈递增趋势(分别为30.8%、51.2%、67.5%,P for trend=0.001)。RVED/LVED为预测肺栓塞的独立影响因素,对比Tertle1组,Tertle2组与Tertle3组发生肺栓塞的风险比分别为3.690~5.216(P均<0.05)和5.673~9.627(P均<0.05),并呈趋势性增加(P for trend<0.05)。RVED/LVED与D-二聚体诊断肺栓塞的曲线下面积(AUC)分别为0.702、0.708,含RVED/LVED肺栓塞诊断模型可增加AUC 0.034(P=0.04)。结论RVED/LVED对肺栓塞的诊断具有一定的临床价值,结合危险因素及临床指标建立模型对肺栓塞的诊断效能更高。
文摘BACKGROUND Coronary heart disease(CHD)causes many adverse cardiovascular events and poses a threat to the patient’s health and quality of life.AIM To evaluate ultrasonography for evaluation of cardiac function and lesion degree in patients with CHD.METHODS A total of 106 patients with CHD(study group)and 106 healthy individuals(control group)in our hospital from March 2019 to September 2020 were selected for this study.All subjects were examined by ultrasound,and the mitral orifice’s early-to-late diastolic blood flow velocity ratio(E/A),left ventricular end-diastolic volume(LVDd),and left atrial diameter(LAD)were measured.Values were compared between the study group and healthy group,and the correlation between the ultrasonic parameters of patients with different cardiac function grades and the degree of CHD were assessed.In addition,the ultrasonic parameters of patients with different prognoses were compared after a follow-up for 6 mo.RESULTS E/A(1.46±0.34)of the study group was smaller than that of the control group(1.88±0.44),while LVDd(58.24±5.05 mm)and LAD(43.31±4.38 mm)were larger(48.15±3.93 and 34.94±2.81,respectively;P<0.05).E/A for patients with grade III disease(1.41±0.43)was smaller and their LVDd(60.04±4.21 mm)and LA(44.16±2.79 mm)were larger than those in patients with grade II disease(1.71±0.48,52.18±3.67 mm,and 39.68±2.37,respectively;P<0.05).Patients with grade IV disease had smaller E/A(1.08±0.39)and larger LVDd(66.81±5.39 mm)and LAD(48.81±3.95 mm)than patients with grade II and III disease(P<0.05).In patients with moderate disease,E/A(1.44±0.41)was smaller and LVDd(59.95±4.14 mm)and LAD(45.15±2.97 mm)were larger than in patients with mild disease(1.69±0.50,51.97±3.88 and 38.81±2.56 mm,respectively;P<0.05).In patients with severe disease,E/A(1.13±0.36)was smaller and LVDd(67.70±6.11 mm)and LAD(49.09±4.05 mm)were larger than in patients with moderate disease(P<0.05).E/A was negatively correlated with cardiac function classi-fication and disease severity,while LVDd and LAD were positively correlated with cardiac function classification and disease severity(P<0.05).E/A(1.83±0.51)for patients with good prognosis was higher than that for those with poor prognosis(1.39±0.32),while LVDd(49.60±4.39 mm)and LAD(36.13±3.05 mm)were lower(P<0.05).CONCLUSION The ultrasonic parameters of patients with CHD are abnormal,and differ significantly in patients with different cardiac function grades,lesion degree,and prognosis.
