Objective:To study the change of left ventricular ultrasonic functional parameters in patients with ACS during peri-PCI period and their relationship with degree of serum myocardial damage.Methods:A total of 76 cases ...Objective:To study the change of left ventricular ultrasonic functional parameters in patients with ACS during peri-PCI period and their relationship with degree of serum myocardial damage.Methods:A total of 76 cases of ACS patients who were treated in our hospital between June 2012 and January 2016 were selected as research subjects, treatment methods were reviewed and then all patients were divided into observation group (n=57) who underwent PCI treatment and control group (n=19) who conformed to PCI indications but underwent conservative treatment under patients' or families' insistence. Left ventricular ultrasonic functional parameter levels and serum myocardial injury index contents were compared between two groups of patients before and after treatment. Pearson test was used to evaluate the relationship between left ventricular ultrasonic functional parameters and myocardial injury in patients with ACS.Results: Before treatment, differences in left ventricular ultrasonic functional parameter levels as well as serum contents of myocardial enzyme spectrum and myocardial apoptosis indexes were not statistically significant between the two groups of patients. After treatment, left ventricular ultrasonic functional parameters LVEDD and LVESD levels in observation group were lower than those in control group while SV level was higher than that in control group;serum contents of myocardial enzyme spectrum cTnT, LDH, CK-MB and AST were lower than those in control group;serum contents of myocardial apoptosis indexes Fas, Caspase-3 and caspase-12 were lower than those in control group while Bcl-2 content was higher than that in control group. The left ventricular ultrasonic functional parameters in ACS patients were directly correlated with the degree of myocardial injury.Conclusion: PCI treatment of patients with ACS can significantly improve left ventricular function and reduce myocardial injury. After treatment, the left ventricular ultrasonic functional parameters are directly correlated with the degree of myocardial injury.展开更多
目的探讨一种新型Visionwire标测导丝在心脏再同步化治疗(CRT)左室电极植入过程中的应用价值。方法 5例因心力衰竭接受CRT的患者,分别采用Visionwire导丝及左室电极到达可植入左室电极的冠状静脉(CS)分支内进行起搏参数测试及电生理标测...目的探讨一种新型Visionwire标测导丝在心脏再同步化治疗(CRT)左室电极植入过程中的应用价值。方法 5例因心力衰竭接受CRT的患者,分别采用Visionwire导丝及左室电极到达可植入左室电极的冠状静脉(CS)分支内进行起搏参数测试及电生理标测,比较两种方法的起搏参数测试、电生理标测结果及手术时间。结果在5例患者的16个CS分支中,两种方法所测的起搏参数值无显著性差异,二者的起搏阈值有强相关性(r=0.90,P<0.01),感知亦有相关性(r=0.67,P<0.01),二者最大起搏电压引起膈肌刺激的部位相似。应用Visionwire导丝可以进行局部电位电激动顺序标测。Visionwire导丝对单个CS分支进行起搏参数测定比应用左室电极进行起搏参数测定所需时间明显缩短(12.4±7.5 min vs 18.3±12.2 min,P<0.01)。结论应用Visionwire标测导丝可以预测CS分支的左室电极起搏参数,根据局部电位延迟可准确定位左室电极植入部位。展开更多
文摘Objective:To study the change of left ventricular ultrasonic functional parameters in patients with ACS during peri-PCI period and their relationship with degree of serum myocardial damage.Methods:A total of 76 cases of ACS patients who were treated in our hospital between June 2012 and January 2016 were selected as research subjects, treatment methods were reviewed and then all patients were divided into observation group (n=57) who underwent PCI treatment and control group (n=19) who conformed to PCI indications but underwent conservative treatment under patients' or families' insistence. Left ventricular ultrasonic functional parameter levels and serum myocardial injury index contents were compared between two groups of patients before and after treatment. Pearson test was used to evaluate the relationship between left ventricular ultrasonic functional parameters and myocardial injury in patients with ACS.Results: Before treatment, differences in left ventricular ultrasonic functional parameter levels as well as serum contents of myocardial enzyme spectrum and myocardial apoptosis indexes were not statistically significant between the two groups of patients. After treatment, left ventricular ultrasonic functional parameters LVEDD and LVESD levels in observation group were lower than those in control group while SV level was higher than that in control group;serum contents of myocardial enzyme spectrum cTnT, LDH, CK-MB and AST were lower than those in control group;serum contents of myocardial apoptosis indexes Fas, Caspase-3 and caspase-12 were lower than those in control group while Bcl-2 content was higher than that in control group. The left ventricular ultrasonic functional parameters in ACS patients were directly correlated with the degree of myocardial injury.Conclusion: PCI treatment of patients with ACS can significantly improve left ventricular function and reduce myocardial injury. After treatment, the left ventricular ultrasonic functional parameters are directly correlated with the degree of myocardial injury.
文摘目的探讨一种新型Visionwire标测导丝在心脏再同步化治疗(CRT)左室电极植入过程中的应用价值。方法 5例因心力衰竭接受CRT的患者,分别采用Visionwire导丝及左室电极到达可植入左室电极的冠状静脉(CS)分支内进行起搏参数测试及电生理标测,比较两种方法的起搏参数测试、电生理标测结果及手术时间。结果在5例患者的16个CS分支中,两种方法所测的起搏参数值无显著性差异,二者的起搏阈值有强相关性(r=0.90,P<0.01),感知亦有相关性(r=0.67,P<0.01),二者最大起搏电压引起膈肌刺激的部位相似。应用Visionwire导丝可以进行局部电位电激动顺序标测。Visionwire导丝对单个CS分支进行起搏参数测定比应用左室电极进行起搏参数测定所需时间明显缩短(12.4±7.5 min vs 18.3±12.2 min,P<0.01)。结论应用Visionwire标测导丝可以预测CS分支的左室电极起搏参数,根据局部电位延迟可准确定位左室电极植入部位。
