Lemierre’s syndrome is a rare and severe sepsis, capable of rapidly compromising the vital prognosis in the absence of early intervention, characterized by an oropharyngeal infection complicated by septic thrombosis ...Lemierre’s syndrome is a rare and severe sepsis, capable of rapidly compromising the vital prognosis in the absence of early intervention, characterized by an oropharyngeal infection complicated by septic thrombosis of the internal jugular vein and the formation of septic emboli primarily localized at the pulmonary level. We report the case of a 14-year-old boy, with no notable pathological history, who had presented for 15 days with unilateral orbital swelling which then became bilateral, all evolving in a context of fever.展开更多
A54-year-old male smoker was admitted to our .hospital after undergoing the drainage of a leftperitonsillar abscess. Ten days prior to admission （day 1）, he complained of a ＂scratchy＂ throat with a fever of 38.5℃...A54-year-old male smoker was admitted to our .hospital after undergoing the drainage of a leftperitonsillar abscess. Ten days prior to admission （day 1）, he complained of a ＂scratchy＂ throat with a fever of 38.5℃. He had an enlarged left tonsil with prominent exudate; white blood cell count （WCC） 8.8×109/L; platelet count （Plt） 103 × 109/L; chest X-ray was normal in a medical clinic. Then the patient received an intravenous injection of 4 million units of penicillin G every 6 hours and 500 mg of oral azithromycin once daily. But his condition worsened with a temperature of 41℃ and laryngoscopy confirmed a marked left-sided peritonsillar abscess which was drained. On day 10, the patient was transferred to our hospital after developing persistent fever, rigors, left-sided neck pain, pain on swallowing and purulent bloody sputum.展开更多
A 17-year-old male with no significant past medical history presented to the emergency department with severe sepsis of unknown etiology. The patient was found to have septic thrombophlebitis of the internal jugular v...A 17-year-old male with no significant past medical history presented to the emergency department with severe sepsis of unknown etiology. The patient was found to have septic thrombophlebitis of the internal jugular vein with multiorgan dysfunction and septic embolization to both lungs. The patient was also noted to have COVID-19 IgM antibodies and multiple close COVID-19 exposures prior to the patient’s emergency department presentation. Here, we present the prolonged and complicated hospitalization of this patient and a review of this rare but important disease.展开更多
Otitis media is common in children and Fusobacterium species are an emerging causative pathogen.These species have virulence factors which increase the risk of complicated otitis media.We discuss a case of F.necrophor...Otitis media is common in children and Fusobacterium species are an emerging causative pathogen.These species have virulence factors which increase the risk of complicated otitis media.We discuss a case of F.necrophorum infection resulting in significant intracranial disease to highlight the epidemiology of these infections,risk factors for complicated disease and signs and symptoms to guide diagnosis and investigation.展开更多
Introduction Campylobacter rectus is a Gram-negative,anaerobic rod,first described in 1981 as Wolinella recta,subsequently re-classified to Campylobacter based on phylogenetic analysis in 1991.1 It is found in the ora...Introduction Campylobacter rectus is a Gram-negative,anaerobic rod,first described in 1981 as Wolinella recta,subsequently re-classified to Campylobacter based on phylogenetic analysis in 1991.1 It is found in the oral cavity and gastrointestinal tract,and is mainly implicated in oral and periodontal infections.So far,there are only a handful of case reports in the literature describing extra-oral invasive C.rectus infections.2–6 Recently,we described a case of fatal C.rectus infection,due to subdural empyema and ruptured mycotic intracranial aneurysm.2 In this article,we report a case of Lemierre’s syndrome associated with C.rectus bacteremia.展开更多
文摘Lemierre’s syndrome is a rare and severe sepsis, capable of rapidly compromising the vital prognosis in the absence of early intervention, characterized by an oropharyngeal infection complicated by septic thrombosis of the internal jugular vein and the formation of septic emboli primarily localized at the pulmonary level. We report the case of a 14-year-old boy, with no notable pathological history, who had presented for 15 days with unilateral orbital swelling which then became bilateral, all evolving in a context of fever.
文摘A54-year-old male smoker was admitted to our .hospital after undergoing the drainage of a leftperitonsillar abscess. Ten days prior to admission （day 1）, he complained of a ＂scratchy＂ throat with a fever of 38.5℃. He had an enlarged left tonsil with prominent exudate; white blood cell count （WCC） 8.8×109/L; platelet count （Plt） 103 × 109/L; chest X-ray was normal in a medical clinic. Then the patient received an intravenous injection of 4 million units of penicillin G every 6 hours and 500 mg of oral azithromycin once daily. But his condition worsened with a temperature of 41℃ and laryngoscopy confirmed a marked left-sided peritonsillar abscess which was drained. On day 10, the patient was transferred to our hospital after developing persistent fever, rigors, left-sided neck pain, pain on swallowing and purulent bloody sputum.
文摘A 17-year-old male with no significant past medical history presented to the emergency department with severe sepsis of unknown etiology. The patient was found to have septic thrombophlebitis of the internal jugular vein with multiorgan dysfunction and septic embolization to both lungs. The patient was also noted to have COVID-19 IgM antibodies and multiple close COVID-19 exposures prior to the patient’s emergency department presentation. Here, we present the prolonged and complicated hospitalization of this patient and a review of this rare but important disease.
文摘Otitis media is common in children and Fusobacterium species are an emerging causative pathogen.These species have virulence factors which increase the risk of complicated otitis media.We discuss a case of F.necrophorum infection resulting in significant intracranial disease to highlight the epidemiology of these infections,risk factors for complicated disease and signs and symptoms to guide diagnosis and investigation.
基金supported by funding from the Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases,the Ministry of Education of China.
文摘Introduction Campylobacter rectus is a Gram-negative,anaerobic rod,first described in 1981 as Wolinella recta,subsequently re-classified to Campylobacter based on phylogenetic analysis in 1991.1 It is found in the oral cavity and gastrointestinal tract,and is mainly implicated in oral and periodontal infections.So far,there are only a handful of case reports in the literature describing extra-oral invasive C.rectus infections.2–6 Recently,we described a case of fatal C.rectus infection,due to subdural empyema and ruptured mycotic intracranial aneurysm.2 In this article,we report a case of Lemierre’s syndrome associated with C.rectus bacteremia.
