AIM：To determine the repeatability of Ophtha Top topography and assess the consistency with intraocular lens（IOL）-Master and Lenstar LS900（Lenstar）in measuring corneal parameters among cataract patients.METHODS：...AIM：To determine the repeatability of Ophtha Top topography and assess the consistency with intraocular lens（IOL）-Master and Lenstar LS900（Lenstar）in measuring corneal parameters among cataract patients.METHODS：Totally 125 eyes were enrolled.Corneas were successively measured with Ophtha Top,IOL-Master and Lenstar at least three times.The flattest meridian power（Kf）,the steepest meridian power（Ks）,mean power（Km）,J0 and J45 were recorded.Intra-class correlation coefficients（ICCs）,the coefficient of variance（COV）,within subject standard deviation（Sw）,and test-retest repeatability（2.77Sw）were adopted to determine the repeatability.The 95%limit of agreement（95%LOA）and Bland-Altman plots were used to assess comparability.RESULTS：Repeatability of Ophtha Top topography for measuring corneal parameters showed the ICCs were all above 0.93,2.77Sw was lower than 0.31,and the COV of the Kf and Ks was lower than 0.25.The keratometric readings with Ophtha Top topography were flatter than with the IOLMaster and Lenstar devices,while the Pearson correlation coefficients were over 0.97.The J0 and J45 with Ophtha Top topography were smaller compared with Lenstar and IOL-Master,while was comparable between Lenstar and IOL-Master.CONCLUSION：Ophtha Top topography shows excellent repeatability for measuring corneal parameters.However,differences between the Ophtha TOP topography and Lenstar,IOL-Master both in cornea curvature and the astigmatism should be noted clinically.展开更多
目的:评估国产眼生物测量仪FAL-1000A与进口眼生物测量仪Lenstar LS 900这2种设备测量屈光不正人群眼生物学参数的一致性。方法:系列病例研究。连续选取2022年8—9月在首都医科大学附属北京同仁医院眼科屈光手术中心就诊并符合入选标准...目的:评估国产眼生物测量仪FAL-1000A与进口眼生物测量仪Lenstar LS 900这2种设备测量屈光不正人群眼生物学参数的一致性。方法:系列病例研究。连续选取2022年8—9月在首都医科大学附属北京同仁医院眼科屈光手术中心就诊并符合入选标准的受检者386例(386眼)。采用国产眼生物测量仪FAL-1000A及进口眼生物测量仪Lenstar LS 900测量并记录眼轴长度(AL)、角膜平坦轴曲率(K1)、角膜陡峭轴曲率(K2)、平均角膜曲率(Km)、眼轴曲率比[眼轴/曲率半径(AL/CR)]等眼部生物学参数;并分别采用配对t检验、Pearson相关分析及Bland-Altman分析评估2种设备测量值的差异性、相关性及一致性。结果:FAL-1000A测量AL、K1,K2及AL/CR值均低于Lenstar LS 900的测量,差异均有统计学意义(均P<0.05)。FAL-1000A与Lenstar LS 900测量的AL、K1、K2、Km、AL/CR具有高度相关性(r=0.98、0.98、0.98、0.99、0.97,均P<0.001)。Bland-Altman分析显示AL、K1、K2、Km及AL/CR的95%一致性界限(95%LoA)分别为-0.247~0.164 mm、-0.366~0.529、-0.689~0.454、-0.412~0.372、-0.067~0.054,分别有3.6%、3.9%、3.6%、4.1%、3.1%点位于95%LoA之外,均显示2种设备获取生物学参数良好的一致性。结论:FAL-1000A作为1种新型的国产光学生物测量仪,与Lenstar LS 900测量的AL、角膜曲率、AL/CR等参数比较,具有良好的一致性,可用于屈光不正人群眼生物学参数评估。展开更多
目的:比较角膜生物力学分析仪(Corvis ST)、A型超声测厚仪(A超)、Lenstar LS 900(Lenstar)在测量近视眼角膜厚度的差异,为屈光术前筛查提供参考。方法:纳入2020年3至12月佛山市第二人民医院收治的屈光术前近视患者244例(244只右眼),并...目的:比较角膜生物力学分析仪(Corvis ST)、A型超声测厚仪(A超)、Lenstar LS 900(Lenstar)在测量近视眼角膜厚度的差异,为屈光术前筛查提供参考。方法:纳入2020年3至12月佛山市第二人民医院收治的屈光术前近视患者244例(244只右眼),并按中央角膜厚度(central corneal thickness,CCT)将患者分为3组:薄角膜组(CCT≤520μm)、正常角膜组(520μm<CCT≤570μm)、厚角膜组(CCT>570μm),分别采用Corvis ST、A超、Lenstar三种仪器测量3组患者的中央角膜厚度,并纳入对比指标。结果:Cor vis ST与A超、Lenstar在薄角膜组、正常角膜组、厚角膜组的测量值对比差异均有统计学意义(均P<0.05);在相关性方面,Corvis ST与A超、Lenstar在薄角膜组、正常角膜组、厚角膜组呈正相关(r=0.841,P<0.001 vs r=0.832,P<0.001;r=0.866,P<0.001 vs r=0.918,P<0.001;r=0.497,P<0.001 vs r=0.801,P<0.001);在一致性方面,Corvis ST与A超、Lenstar在薄角膜组、正常角膜组、厚角膜组上一致性系数ICC及95%置信区间分别为0.602(0.091,0.857),0.758(0.221,0.901)、0.741(0.207,0.890),0.845(0.396,0.938)、0.417(0.005,0.679),0.667(0.172,0.851),95%一致性区间范围分别是(−2.2~24.2μm,−6.7~19.5μm;−8.4~24.6μm,−6.8~19.4μm;−8.7~23.8μm,−7.0~18.3μm)。结论:通过对3组数据统计分析得出,Corvis ST与A超、Lens tar的测量值相比,差异均有统计学意义,且Corvis ST的测量值均高于后两种仪器;Cor vis ST与后两者均有着较高的相关性,且在正常角膜厚度测量上相关性最高;在一致性方面,从ICC点估计及95%置信区间数值分析,一致性较差;从Bland-Altman角度分析,Corvis ST与后两者的绝对值最大差值超过10μm,一致性较差,但在与Lenstar的绝对值最大差值均在20μm内。因此,在测量精度要求较高的屈光手术筛查方面,Corvis ST与A超、Lenstar之间不能相互替代,而对于大规模临床筛查,其角膜厚度测量值对眼压的影响有一定的临床参考意义。展开更多
文摘AIM：To determine the repeatability of Ophtha Top topography and assess the consistency with intraocular lens（IOL）-Master and Lenstar LS900（Lenstar）in measuring corneal parameters among cataract patients.METHODS：Totally 125 eyes were enrolled.Corneas were successively measured with Ophtha Top,IOL-Master and Lenstar at least three times.The flattest meridian power（Kf）,the steepest meridian power（Ks）,mean power（Km）,J0 and J45 were recorded.Intra-class correlation coefficients（ICCs）,the coefficient of variance（COV）,within subject standard deviation（Sw）,and test-retest repeatability（2.77Sw）were adopted to determine the repeatability.The 95%limit of agreement（95%LOA）and Bland-Altman plots were used to assess comparability.RESULTS：Repeatability of Ophtha Top topography for measuring corneal parameters showed the ICCs were all above 0.93,2.77Sw was lower than 0.31,and the COV of the Kf and Ks was lower than 0.25.The keratometric readings with Ophtha Top topography were flatter than with the IOLMaster and Lenstar devices,while the Pearson correlation coefficients were over 0.97.The J0 and J45 with Ophtha Top topography were smaller compared with Lenstar and IOL-Master,while was comparable between Lenstar and IOL-Master.CONCLUSION：Ophtha Top topography shows excellent repeatability for measuring corneal parameters.However,differences between the Ophtha TOP topography and Lenstar,IOL-Master both in cornea curvature and the astigmatism should be noted clinically.
文摘目的:评估国产眼生物测量仪FAL-1000A与进口眼生物测量仪Lenstar LS 900这2种设备测量屈光不正人群眼生物学参数的一致性。方法:系列病例研究。连续选取2022年8—9月在首都医科大学附属北京同仁医院眼科屈光手术中心就诊并符合入选标准的受检者386例(386眼)。采用国产眼生物测量仪FAL-1000A及进口眼生物测量仪Lenstar LS 900测量并记录眼轴长度(AL)、角膜平坦轴曲率(K1)、角膜陡峭轴曲率(K2)、平均角膜曲率(Km)、眼轴曲率比[眼轴/曲率半径(AL/CR)]等眼部生物学参数;并分别采用配对t检验、Pearson相关分析及Bland-Altman分析评估2种设备测量值的差异性、相关性及一致性。结果:FAL-1000A测量AL、K1,K2及AL/CR值均低于Lenstar LS 900的测量,差异均有统计学意义(均P<0.05)。FAL-1000A与Lenstar LS 900测量的AL、K1、K2、Km、AL/CR具有高度相关性(r=0.98、0.98、0.98、0.99、0.97,均P<0.001)。Bland-Altman分析显示AL、K1、K2、Km及AL/CR的95%一致性界限(95%LoA)分别为-0.247~0.164 mm、-0.366~0.529、-0.689~0.454、-0.412~0.372、-0.067~0.054,分别有3.6%、3.9%、3.6%、4.1%、3.1%点位于95%LoA之外,均显示2种设备获取生物学参数良好的一致性。结论:FAL-1000A作为1种新型的国产光学生物测量仪,与Lenstar LS 900测量的AL、角膜曲率、AL/CR等参数比较,具有良好的一致性,可用于屈光不正人群眼生物学参数评估。
文摘目的:比较角膜生物力学分析仪(Corvis ST)、A型超声测厚仪(A超)、Lenstar LS 900(Lenstar)在测量近视眼角膜厚度的差异,为屈光术前筛查提供参考。方法:纳入2020年3至12月佛山市第二人民医院收治的屈光术前近视患者244例(244只右眼),并按中央角膜厚度(central corneal thickness,CCT)将患者分为3组:薄角膜组(CCT≤520μm)、正常角膜组(520μm<CCT≤570μm)、厚角膜组(CCT>570μm),分别采用Corvis ST、A超、Lenstar三种仪器测量3组患者的中央角膜厚度,并纳入对比指标。结果:Cor vis ST与A超、Lenstar在薄角膜组、正常角膜组、厚角膜组的测量值对比差异均有统计学意义(均P<0.05);在相关性方面,Corvis ST与A超、Lenstar在薄角膜组、正常角膜组、厚角膜组呈正相关(r=0.841,P<0.001 vs r=0.832,P<0.001;r=0.866,P<0.001 vs r=0.918,P<0.001;r=0.497,P<0.001 vs r=0.801,P<0.001);在一致性方面,Corvis ST与A超、Lenstar在薄角膜组、正常角膜组、厚角膜组上一致性系数ICC及95%置信区间分别为0.602(0.091,0.857),0.758(0.221,0.901)、0.741(0.207,0.890),0.845(0.396,0.938)、0.417(0.005,0.679),0.667(0.172,0.851),95%一致性区间范围分别是(−2.2~24.2μm,−6.7~19.5μm;−8.4~24.6μm,−6.8~19.4μm;−8.7~23.8μm,−7.0~18.3μm)。结论:通过对3组数据统计分析得出,Corvis ST与A超、Lens tar的测量值相比,差异均有统计学意义,且Corvis ST的测量值均高于后两种仪器;Cor vis ST与后两者均有着较高的相关性,且在正常角膜厚度测量上相关性最高;在一致性方面,从ICC点估计及95%置信区间数值分析,一致性较差;从Bland-Altman角度分析,Corvis ST与后两者的绝对值最大差值超过10μm,一致性较差,但在与Lenstar的绝对值最大差值均在20μm内。因此,在测量精度要求较高的屈光手术筛查方面,Corvis ST与A超、Lenstar之间不能相互替代,而对于大规模临床筛查,其角膜厚度测量值对眼压的影响有一定的临床参考意义。
