Objective:To observe the clinical efficacy of umbilical therapy with herbal cakes made of Ge Gen Qin Lian Tang prescription of different dosages in treating damp-heat diarrhea in young children.Methods:Seventy-two kid...Objective:To observe the clinical efficacy of umbilical therapy with herbal cakes made of Ge Gen Qin Lian Tang prescription of different dosages in treating damp-heat diarrhea in young children.Methods:Seventy-two kids with diarrhea of damp-heat pattern were recruited and divided into a high-dosage group and a low-dosage group using the random number table method,with 36 cases in each group.They all received conventional antidiarrheal treatment and umbilical application with herbal cakes.However,the herbal cakes for the high-dosage group were made of the mixture of Ge Gen Qin Lian Tang powder and water,and those for the low-dosage group consisted of 10%Ge Gen Qin Lian Tang powder and 90%auxiliary materials(corn starch)plus water.The treatment duration was 3 d.The clinical efficacy,antidiarrheal rate,effective rate for symptoms and signs of traditional Chinese medicine(TCM),TCM symptoms score,and safety indicators were compared between the two groups.Results:After the treatment,the TCM symptoms scores dropped significantly in both groups(P<0.01)and were lower in the high-dosage group than in the low-dosage group(P<0.05).The clinical efficacy was more significant in the high-dosage group than in the low-dosage group after the treatment,and the between-group difference was statistically significant(P<0.05);the antidiarrheal rate was markedly higher in the high-dosage group than in the low-dosage group(P<0.05).Regarding the TCM symptoms and signs,the high-dosage group showed better results in improving the greasy and yellowish tongue coating,bowel movement frequency,watery excrement,short and dark urine,red tongue body,red anus,vomiting,bowel sounds,and abdominal bloating compared with the low-dosage group,and the between-group differences were statistically significant(P<0.01).Conclusion:Umbilical therapy with herbal cakes made of Ge Gen Qin Lian Tang is safe,reliable,and effective in treating damp-heat diarrhea in young children;the high-dosage herbal cakes produce more significant efficacy than the low-dosage ones and are worth further investigation.展开更多
文摘Objective:To observe the clinical efficacy of umbilical therapy with herbal cakes made of Ge Gen Qin Lian Tang prescription of different dosages in treating damp-heat diarrhea in young children.Methods:Seventy-two kids with diarrhea of damp-heat pattern were recruited and divided into a high-dosage group and a low-dosage group using the random number table method,with 36 cases in each group.They all received conventional antidiarrheal treatment and umbilical application with herbal cakes.However,the herbal cakes for the high-dosage group were made of the mixture of Ge Gen Qin Lian Tang powder and water,and those for the low-dosage group consisted of 10%Ge Gen Qin Lian Tang powder and 90%auxiliary materials(corn starch)plus water.The treatment duration was 3 d.The clinical efficacy,antidiarrheal rate,effective rate for symptoms and signs of traditional Chinese medicine(TCM),TCM symptoms score,and safety indicators were compared between the two groups.Results:After the treatment,the TCM symptoms scores dropped significantly in both groups(P<0.01)and were lower in the high-dosage group than in the low-dosage group(P<0.05).The clinical efficacy was more significant in the high-dosage group than in the low-dosage group after the treatment,and the between-group difference was statistically significant(P<0.05);the antidiarrheal rate was markedly higher in the high-dosage group than in the low-dosage group(P<0.05).Regarding the TCM symptoms and signs,the high-dosage group showed better results in improving the greasy and yellowish tongue coating,bowel movement frequency,watery excrement,short and dark urine,red tongue body,red anus,vomiting,bowel sounds,and abdominal bloating compared with the low-dosage group,and the between-group differences were statistically significant(P<0.01).Conclusion:Umbilical therapy with herbal cakes made of Ge Gen Qin Lian Tang is safe,reliable,and effective in treating damp-heat diarrhea in young children;the high-dosage herbal cakes produce more significant efficacy than the low-dosage ones and are worth further investigation.
