ZHOU Bai-Bin *,1,2 WEI Yong-De 1 LI Zhong-Hua 1 ( 1 Department of Applied Chemistry,Ha rbin Institute of Technology ￡?Harbin￡±￡ì￡°￡°￡°￡±￡(c)( 2 Department of Chemistry,Harbin Norm...ZHOU Bai-Bin *,1,2 WEI Yong-De 1 LI Zhong-Hua 1 ( 1 Department of Applied Chemistry,Ha rbin Institute of Technology ￡?Harbin￡±￡ì￡°￡°￡°￡±￡(c)( 2 Department of Chemistry,Harbin Normal University￡?Harbin￡±￡ì￡°￡°￡?￡°￡(c) The air-solid interface reaction of Ce,Lu with K10 H 3[Gd (SiMo 4 W￡*O￡3￡1￡(c) 2]through chemistry-heated permeation is reported for the fi rst time￡(r)The permeated complex is characterized by ICP and the result shows tha t the mini mum Ce,Lu can permeate into the inner sph ere of K 10 H ￡3 ￡?Gd ￡¨SiMo ￡′ W ￡* O ￡3￡1 ￡(c) 2]The IR ,XRD patterns give the eviden ce that after permeation the comple x still keeps the Keggin structure,howe ver,its crystal structure is different from the complex before permeation￡(r)The cond uctivity of the permeated complex has been measured with the four-electr ode method and the data show that the co nductivity of the complex after permeation is 10 6 times higher than that of the sample before permeation and reaches ￡′￡(r)84 6×10 -1 S·cm -1 ￡(r)These indicate that the permeated c omplex is a good solid electrolyte and further appli cations are also expected￡(r)展开更多
Nanoscale RE^3＋ （RE=Ce, Tb） doped and codoped lutetium pyrosilicate Lu2Si2O7（LPS） phosphors were prepared by using the sol-gel method. Heat treatment was performed in the temperature range from 900 to 1100 ℃. Th...Nanoscale RE^3＋ （RE=Ce, Tb） doped and codoped lutetium pyrosilicate Lu2Si2O7（LPS） phosphors were prepared by using the sol-gel method. Heat treatment was performed in the temperature range from 900 to 1100 ℃. The crystal structure was analyzed by X-ray diffraction （XRD）. The results showed that the β-type structure of LPS was obtained at 1100 ℃. The excitation spectra in the UV and VUV ranges and the emission spectra of the samples were measured at room temperature, and their luminescent properties were studied. The energy transfer from Ce^3＋ to Tb^3＋ in the codoped samples were observed and discussed.展开更多
Coronavirus (CoVID-19) is a new outbreak of coronavirus disease which started in the Wuhan, China, the spread of this virus has now reached a global stage, urgent need is therefore needed to find new drug molecules wh...Coronavirus (CoVID-19) is a new outbreak of coronavirus disease which started in the Wuhan, China, the spread of this virus has now reached a global stage, urgent need is therefore needed to find new drug molecules which can either be used as a first aid intervention or slow down the multiplication rate of the virus within the system. In order to address this, this research looked into the existing antiviral drugs and screened them for their inhibitory properties towards the CoVID-19 protein. Recently, the crystal structure of the CoVID-19 (6LU7) protein has been established, this gives us the possible drug target site in CoVID-19. The binding affinity of the six compounds was screened using MOE (Molecular Operating Environment) software, four compounds (Zanamivir, Peramivir, Rimantidine, and Oseltamivir) out these six compounds have been approved by the Food Drug and Administration (FDA). The molecular docking calculation, Higher Occupied Molecular Orbital (HOMO) and Lowest Unoccupied Molecular Orbital (LUMO) calculation were used to hypothesise the bioactivity of the FDA approved drug against the CoVID-19 protein. The calculation showed that Pimodivir tops the list of the anti influenza drug which can be used as first aid treatment for patient. Apart from Pimodivir, Laninamivir Octanoate is also a very good drug which might be used to inhibit CoVID-19 protein. It was also discovered that based on binding property of Rimantadine, it might be suitable for Fragment Based Drug Design (FBDD) approach which might lead to the discovery of completely new drug entity. Stability of the new protein structure was studied using GROMACS molecular dynamic simulation software. The results showed that the stability of the protein structure was achieved over a range of time, this confirmed that 6LU7 crystal structure might be a suitable protein crystal structure suitable for the development of new drug towards the treatment of CoVID-19. Finally, based on the molecular docking result, Pimodivir and Laninamivir Octanoate might be useful in the treatment of infected patient.展开更多
We study the ferromagnetic criticality of the pyrochlore magnet Lu2 V2 O7 at the ferromagnetic transition TC% 70 K from the isotherms of magnetization MeHT via an iteration process and the Kouvel-Fisher method. The cr...We study the ferromagnetic criticality of the pyrochlore magnet Lu2 V2 O7 at the ferromagnetic transition TC% 70 K from the isotherms of magnetization MeHT via an iteration process and the Kouvel-Fisher method. The critical exponents associated with the transition are determined: b = 0.32(1), c = 1.41(1),and d ? 5:38. The validity of these critical exponents is further verified by scaling all the MeHT data in the vicinity of TConto two universal curves in the plot of M=jejbversus H=jejbtc, where e ? T=TCà 1.The obtained b and c values show asymmetric behaviors on the T < TCand the T > TCsides, and are consistent with the predicted values of 3 D Ising and cubic universality classes, respectively. This makes Lu2 V2 O7 a rare example in which the critical behaviors associated with a ferromagnetic transition belong to different universality classes. We describe the observed criticality from the Ginzburg-Landau theory with the quartic cubic anisotropy that microscopically originates from the anti-symmetric Dzyaloshinskii-Moriya interaction as revealed by recent magnon thermal Hall effect and theoretical investigations.展开更多
To improve the corrosion resistance of porous Si3N4 used in the high temperature environments,which contain water vapor and volatile species,porous Si3N4-Lu2Si2O7 composite ceramics were fabricated by a process of oxi...To improve the corrosion resistance of porous Si3N4 used in the high temperature environments,which contain water vapor and volatile species,porous Si3N4-Lu2Si2O7 composite ceramics were fabricated by a process of oxidation bonding and pressureless sintering in flowing N 2 atmosphere at the temperatures lower than 1550 ° C.The pores in ceramics were formed by removing the pore-forming agent（phenolic resin）.SiO2 derived by the oxidation of Si3N4 at 1250 ° C in air reacted with Lu2O3 at various sintering temperatures,leading to the formation of Lu2Si2O7 with excellent oxidation and corrosion resistance.The phase composition,microstructure,and mechanical properties of the porous ceramics depended on the sintering temperatures.Si3N4-Lu2Si2O7 composite ceramics with the porosity of 52% and the pore size of 0.2 μm were obtained by oxidation bonding at 1250 ° C for 1 h and pressureless sintering at 1550 ° C for 2 h using 4 wt pct Lu2O3 additive.展开更多
基金National Natural Science Foundation of China under Grants(50772112,90922003,50872135)the Director Foundation of Anhui Institute of Optics and Fine Mechanics
文摘ZHOU Bai-Bin *,1,2 WEI Yong-De 1 LI Zhong-Hua 1 ( 1 Department of Applied Chemistry,Ha rbin Institute of Technology ￡?Harbin￡±￡ì￡°￡°￡°￡±￡(c)( 2 Department of Chemistry,Harbin Normal University￡?Harbin￡±￡ì￡°￡°￡?￡°￡(c) The air-solid interface reaction of Ce,Lu with K10 H 3[Gd (SiMo 4 W￡*O￡3￡1￡(c) 2]through chemistry-heated permeation is reported for the fi rst time￡(r)The permeated complex is characterized by ICP and the result shows tha t the mini mum Ce,Lu can permeate into the inner sph ere of K 10 H ￡3 ￡?Gd ￡¨SiMo ￡′ W ￡* O ￡3￡1 ￡(c) 2]The IR ,XRD patterns give the eviden ce that after permeation the comple x still keeps the Keggin structure,howe ver,its crystal structure is different from the complex before permeation￡(r)The cond uctivity of the permeated complex has been measured with the four-electr ode method and the data show that the co nductivity of the complex after permeation is 10 6 times higher than that of the sample before permeation and reaches ￡′￡(r)84 6×10 -1 S·cm -1 ￡(r)These indicate that the permeated c omplex is a good solid electrolyte and further appli cations are also expected￡(r)
基金the National Natural Science Foundation of China (50332050)Specialized Research Fund for the Doctoral Program of Higher Education (20060358054)
文摘Nanoscale RE^3＋ （RE=Ce, Tb） doped and codoped lutetium pyrosilicate Lu2Si2O7（LPS） phosphors were prepared by using the sol-gel method. Heat treatment was performed in the temperature range from 900 to 1100 ℃. The crystal structure was analyzed by X-ray diffraction （XRD）. The results showed that the β-type structure of LPS was obtained at 1100 ℃. The excitation spectra in the UV and VUV ranges and the emission spectra of the samples were measured at room temperature, and their luminescent properties were studied. The energy transfer from Ce^3＋ to Tb^3＋ in the codoped samples were observed and discussed.
文摘Coronavirus (CoVID-19) is a new outbreak of coronavirus disease which started in the Wuhan, China, the spread of this virus has now reached a global stage, urgent need is therefore needed to find new drug molecules which can either be used as a first aid intervention or slow down the multiplication rate of the virus within the system. In order to address this, this research looked into the existing antiviral drugs and screened them for their inhibitory properties towards the CoVID-19 protein. Recently, the crystal structure of the CoVID-19 (6LU7) protein has been established, this gives us the possible drug target site in CoVID-19. The binding affinity of the six compounds was screened using MOE (Molecular Operating Environment) software, four compounds (Zanamivir, Peramivir, Rimantidine, and Oseltamivir) out these six compounds have been approved by the Food Drug and Administration (FDA). The molecular docking calculation, Higher Occupied Molecular Orbital (HOMO) and Lowest Unoccupied Molecular Orbital (LUMO) calculation were used to hypothesise the bioactivity of the FDA approved drug against the CoVID-19 protein. The calculation showed that Pimodivir tops the list of the anti influenza drug which can be used as first aid treatment for patient. Apart from Pimodivir, Laninamivir Octanoate is also a very good drug which might be used to inhibit CoVID-19 protein. It was also discovered that based on binding property of Rimantadine, it might be suitable for Fragment Based Drug Design (FBDD) approach which might lead to the discovery of completely new drug entity. Stability of the new protein structure was studied using GROMACS molecular dynamic simulation software. The results showed that the stability of the protein structure was achieved over a range of time, this confirmed that 6LU7 crystal structure might be a suitable protein crystal structure suitable for the development of new drug towards the treatment of CoVID-19. Finally, based on the molecular docking result, Pimodivir and Laninamivir Octanoate might be useful in the treatment of infected patient.
基金supported by the National Key R&D Program of China (2018YFA0305700, 2018YFA0305800, 2016YFA0301001 and 2016YFA0300500)the National Natural Science Foundation of China (11574377, 11834016, 11874400)+3 种基金the Strategic Priority Research Program,Key Research Program of Frontier Sciences of the Chinese Academy of Sciences (XDB25000000, XDB07020100 and QYZDB-SSW-SLH013)supported by NSF DMR 1350002. J.P.S.support from the China Postdoctoral Science Foundationthe Postdoctoral Innovative Talent Program
文摘We study the ferromagnetic criticality of the pyrochlore magnet Lu2 V2 O7 at the ferromagnetic transition TC% 70 K from the isotherms of magnetization MeHT via an iteration process and the Kouvel-Fisher method. The critical exponents associated with the transition are determined: b = 0.32(1), c = 1.41(1),and d ? 5:38. The validity of these critical exponents is further verified by scaling all the MeHT data in the vicinity of TConto two universal curves in the plot of M=jejbversus H=jejbtc, where e ? T=TCà 1.The obtained b and c values show asymmetric behaviors on the T < TCand the T > TCsides, and are consistent with the predicted values of 3 D Ising and cubic universality classes, respectively. This makes Lu2 V2 O7 a rare example in which the critical behaviors associated with a ferromagnetic transition belong to different universality classes. We describe the observed criticality from the Ginzburg-Landau theory with the quartic cubic anisotropy that microscopically originates from the anti-symmetric Dzyaloshinskii-Moriya interaction as revealed by recent magnon thermal Hall effect and theoretical investigations.
基金supported by the "Basic Research Fund" of Northwestern Polytechnical University,China (No. W018105)the Fund of the State Key Laboratory of Solidification Processing in Northwestern Polytechnical University, China (No. KB200920)
文摘To improve the corrosion resistance of porous Si3N4 used in the high temperature environments,which contain water vapor and volatile species,porous Si3N4-Lu2Si2O7 composite ceramics were fabricated by a process of oxidation bonding and pressureless sintering in flowing N 2 atmosphere at the temperatures lower than 1550 ° C.The pores in ceramics were formed by removing the pore-forming agent（phenolic resin）.SiO2 derived by the oxidation of Si3N4 at 1250 ° C in air reacted with Lu2O3 at various sintering temperatures,leading to the formation of Lu2Si2O7 with excellent oxidation and corrosion resistance.The phase composition,microstructure,and mechanical properties of the porous ceramics depended on the sintering temperatures.Si3N4-Lu2Si2O7 composite ceramics with the porosity of 52% and the pore size of 0.2 μm were obtained by oxidation bonding at 1250 ° C for 1 h and pressureless sintering at 1550 ° C for 2 h using 4 wt pct Lu2O3 additive.
