Research and Practice on the Training Mode of Innovative and Entrepreneurial Talents in Colleges and Universities:A Case Study of Academic Association of"Federation of Life Science Research and Innovation"

Taking the academic association of the Federation of Life Science Research and Innovation of the College of Life Science and Biotechnology of Heilongjiang Bayi Agricultural University as the research platform,it is necessary to organically combine personalized education with the cultivation of innovative and entrepreneurial ability.On the basis of unified teaching ideas,we should pay attention to the individual differences of educational objects,eliminate the disadvantages of traditional education,and break the conventional"spoon-feeding"teaching mode.It is necessary to shift from only paying attention to one-way indoctrination to paying attention to the cultivation of students'innovative quality,and to enhance students'interest in scientific research and practical ability of innovation and entrepreneurship through the rich scientific research activities of academic associations.

Information in the Universal Triangle of Reality for Non-living/Living Structures:From Philosophy to Neuro/Life Sciences

With the purpose to understand better the role of information not only in communication systems,but actually in our environmental reality,this paper presented the model of Universal Triangle of Reality,composed by Matter,Energy and Information,as fundamental constitutive components of this reality.Arguments coming from the field of physics,both at the cosmic and microparticles scale are presented,showing undoubtable conclusions that information is a fundamental component of reality in our material world.At the cosmic level,where the unusual high concentration of mass in the black holes constitutes a special state of matter,suitable for analysis of their special properties,the problem of the conservation principle of information is discussed.At the quantum level,the special unusual characteristics derived from the non-localization principle are also highlighted,together with information-involved problems and solutions.The Universal Triangle of Reality in the living systems reveals the high role of the involved information,both as the informational common organization on the entire evolution scale,and as the info-dynamics processes inside of own structure and resulted from interaction with the environment.The relevant advances in the approaching and understanding of the functionality of the living systems from informational point of view are highlighted,showing the high contribution of information concepts in understanding/solving of various older/recent problems in philosophy,neuroscience/neurology/psychiatry,neuro-physics/neuropsychology/behavior sciences,geriatrics/gerontology,biology and life sciences.

Membranes for the life sciences and their future roles in medicine

Since the global outbreak of COVID-19,membrane technology for clinical treatments,including extracorporeal membrane oxygenation(ECMO)and protective masks and clothing,has attracted intense research attention for its irreplaceable abilities.Membrane research and applications are now playing an increasingly important role in various fields of life science.In addition to intrinsic properties such as size sieving,dissolution and diffusion,membranes are often endowed with additional functions as cell scaffolds,catalysts or sensors to satisfy the specific requirements of different clinical applications.In this review,we will introduce and discuss state-of-the-art membranes and their respective functions in four typical areas of life science:artificial organs,tissue engineering,in vitro blood diagnosis and medical support.Emphasis will be given to the description of certain specific functions required of membranes in each field to provide guidance for the selection and fabrication of the membrane material.The advantages and disadvantages of these membranes have been compared to indicate further development directions for different clinical applications.Finally,we propose challenges and outlooks for future development.

Space Life Science of China

In the past two years,China’s space life science has made great progress.Space biomedical and life science programs have carried out ground-based research for the first batch of projects,and are preparing to carry out space-based experiments along with the construction of China’s space station.And space life science payload of the space station completed the development of positive samples.Thus,with the development of lunar exploration and Mars exploration projects,astrobiology research has also made a lot of basic achievements.On the basis of summarizing the development of space life science in China,this paper mainly introduces the important progress of payload technology and life science research.

Inductively coupled plasma mass spectrometry (ICP-MS) and its application in life sciences

Inductively-coupled plasma mass spectrometry (ICP-MS) has made much progress since its birth in the late 1990s. This paper will give a rather systematic overview on the use of this technique in new devices and technologies related to plasma source, sample-introducing device and detecting spectrometer etc. In this overview, an emphasis will be put on the evaluation of the ICP- MS technique in combination with a series of physical, chemical and biological techniques, such as laser ablation (LA), capillary electrophoresis (CE) and high performance liquid chromatograph (HPLC), along with their representative high accuracy and high sensitivity. Finally, comprehensive and fruitful applications of the ICP-MS and its combinative techniques in the detection of trace metallic elements and isotopes in complex biological and environmental samples will be revealed.

Space Life Science in China

With the further advancement of China’s major manned spaceflight project,the national space laboratory was successfully built.China has also made considerable progress and breakthroughs in the field of space life sciences.This paper reviews the related biological effects under space flight conditions,mainly including epigenetic effects,skeleton remodeling and peripheral body fluid circulation effects,as well as the research and application of space life science related biotechnology in the field of microbial culture and biological regeneration life support system.

The Impact of Life Sciences Developments on the UK Urban Environment

Life sciences urban developments are a relatively recent phenomenon, and follow the emergence of knowledge based urban developments as a potential driver of urban regeneration and local economic growth. The role of these new centres in transforming the inner cities of some of the UK＇s larger conurbations is examined and the key planning issues are discussed. The article concludes that the key principles of urban planning and control must still apply in shaping the role these new developments have in the UK＇s evolving urban landscape.

Life Sciences in the 21st Century

This article presents a retrospective of the achievements of life sciences in the 20th century and a prospective in the 21 st century.primarily,because of the emergence of molecular biology in the 20th cetury,life sciences have grown up from a descriptive discipline to an exact science.Biology in the 21st century features a unification between analysis and integration,i.e.the unification of analysis and func-tional research.More and more interdisciplinary integration will be based on works of penetrating analyses.Secondly.the deeper understanding of all living phenomena will lead to a unified connition of the essence of life so that general biology in the genuine sese of the term will come into being.finally,basic research on the life sciences will produce an unprecedented influence on all aspects of human life.

CULTIVATION OF TALENTS FOR LIFE SCIENCE

In view of the fact that biology has been exempted from the college entrance examination and the current situation of biology education in China, this article puts forward proposals for strengthening the cultivation of talents for life science, such bringing to Government’s attention, increasing the funds invested, strengthening the liaison between the R&D communities and the institutions of higher learning, reinforcing the biology education in secondary schools, and reestablishing the position of biology in college entrance examinations.

Life Sciences and the Overall Quality of Society

Human survival and develop-ment are closely linked with the lifesciences. Agriculture, population,medicine, the environment andecology, all of them are inseparablefrom the development of life sci-ences and technologies, and it is onlife sciences that the human racedepends for sustainable economicdevelopment in the future.

BLE beacons for sample position estimation in a life science automation laboratory

Estimation of the sample position is essential for working process monitoring and management in the life science automation laboratory.Bluetooth low-energy(BLE)beacons have the advantages of low price,small size and low energy consumption,which make them a promising solution for sample position estimation in the automated laboratory.Several fingerprinting models have been proposed to achieve indoor localization with the received signal strength(RSS)data.However,most of the research depends on intensive beacon installation.Proximity estimation,which depends entirely on one beacon,is more suitable for sample position estimation in large automated laboratories.The complexity of the life science automation laboratory environment brings challenges to the traditional path loss model(PLM),which is a widely used radio wave propagation model-based proximity estimation method.In this paper,BLE sensing devices for sample position estimation are proposed.The BLE beacon-based proximity estimation is discussed in the framework of machine learning,in which the support vector regression(SVR)is utilized to model the nonlinear relationship between the RSS data and distance,and the Kalman filter is utilized to decrease the RSS data deviation.The experimental results over different environments indicate that the SVR outperforms the PLM significantly,and provides 1 m absolute errors for more than 95%of the testing samples.The Kalman filter brings benefits to stable distance predictions.Apart from proximity-based sample position estimation,the proposed framework turned out to be effective in position estimation between parallel workbenches and position estimation on an automated workstation.

Recent Progress in Space Science and Applications on Chinese Space Station in 2022–2024

Chinese Space Station(CSS)has been fully deployed by the end of 2022,and the facility has entered into the application and development phase.It has conducted scientific research projects in various fields,such as space life science and biotechnology,space materials science,microgravity fundamental physics,fluid physics,combustion science,space new technologies,and applications.In this review,we introduce the progress of CSS development and provide an overview of the research conducted in Chinese Space Station and the recent scientific findings in several typical research fields.Such compelling findings mainly concern the rapid solidification of ultra-high temperature alloy melts,dynamics of fluid transport in space,gravity scaling law of boiling heat transfer,vibration fluidization phenomenon of particulate matter,cold atom interferometer technology under high microgravity and related equivalence principle testing,the full life cycle of rice under microgravity and so forth.Furthermore,the planned scientific research and corresponding prospects of Chinese space station in the next few years are presented.

Life Science:Innovation and prosperity—commemorating the 60th anniversary of the Chinese Academy of Sciences

In tandem with the birth and growth of the People’s Republic of China (PRC),the Chinese Academy of Sciences (CAS) passed through six decades by the year of 2009.

Strengthening biological security after COVID-19:Using cartoons for engaging life science stakeholders with the Biological and Toxin Weapons Convention(BTWC)

The devastating effects of the COVID-19 pandemic have acutely shown the need for maintaining robust international and national systems for biological security and ensuring that life sciences are used only for peaceful purposes.Life science stakeholders can play an important role in safeguarding scientific and technological advances in biology and related fields against accidental or deliberate misuse,not least because they are on the frontlines of driving innovation.In this paper,we argue that enhancing awareness and understanding of the risk of deliberate disease is essential for effective biological security.We first discuss the issue of‘dual use’in science and technology as it relates to disarmament and non-proliferation of weapons of mass destruction.Second,we review how scientist engagement with dual-use risks has been addressed in the context of the Biological and Toxin Weapons Convention(BTWC).Third,we report on the development of an innovative awarenessraising tool,a cartoon series,that can be used for engaging life science stakeholders with BTWC issues.Finally,we outline a set of practical considerations for promoting sustainable life science engagement with the BTWC.

Genomics in Space Life Sciences

Since the early days of manned spaceflight, hazardous effects of the space environment on living organisms have been disputed. With the continuous manning of the International Space Station, the planned Chinese space station, and renewed interest in returning to the Moon and sending manned flights to Mars, identifying and addressing the potential outcomes of long-term space exposures is critically important.

Launching the CUSBEA Article Series in SCIENCE CHINA Life Sciences

As a CUSBEA (China-United States Biochemistry Examination and Administration) Program fellow of Class IV (1985), I am very excited to announce the official launch of the CUSBEA Article Series in SCIENCE CHINA

Being the Pioneer of Life Sciences in China——Introduction to Beijing Genomics Institute

The Beijing Genomics Institute (BGI) of Chinese Academy of Sciences (CAS) wasofficially founded in December 2003. Its predecessor, Beijing Huada Genomics Research Center, haspresented significant contributions to the development of life sciences in China by its excellentscientific innovations and achievements in the last five years. From the participation ofInternational Human Genome Project (HGP) to the independent completion of the whole-genome draft andfine maps of Chinese super hybrid rice genome, from the porcine genome research cooperated withDenmark to the international chicken genome research, and from the silkworm genome projectaccomplished together with The Southwest Agriculture University of China to the great contributionsto the national campaign against SARS, all these facts illustrate that BGI not only has afirst-class scientific research power in the world but also is full of devotion to the flourish ofscience and nation. During these years, we have upheld the strategy of ''Advance through projects,strive for innovation, grow through cooperation'', in the aim of making BGI as one of the pioneers ofCAS climbing the peak of life sciences in the world.