The traditional synthetic polypropylene(PP) meshes for hernia surgical repair were controversial due to increasing postoperative complications,including chronic pain,infection and shrinkage.These morbidities may be re...The traditional synthetic polypropylene(PP) meshes for hernia surgical repair were controversial due to increasing postoperative complications,including chronic pain,infection and shrinkage.These morbidities may be related to a mismatch of mechanical properties between abdominal wall and the meshes.The aims of this study were to design a large pore,lightweight and anisotropic hernia mesh material and explore the influence of pulling density on mechanical properties of experimental hernia mesh materials.The hernia mesh material included A,B,and C samples knitted by RS4 EL warp knitting machine with 16 E gauge.The results showed that the mechanical properties of hernia mesh materials met the requirement of anisotropy in abdominal wall tissue.With the pulling density increased,bursting strength,uniaxial tensile strength and suture pulling out force tended to increase,while tearing force was no significant difference.Sample C showed superior physical and mechanical properties.展开更多
目的评价Lichtenstein腹股沟疝修补术中轻量型网片与重量型网片的远期临床疗效及安全性。方法计算机检索Pub Med、EMBASE、The Cochrane图书馆、Web of Science、中国生物医学文献数据库、中国期刊全文数据库、万方数字化期刊群和维普...目的评价Lichtenstein腹股沟疝修补术中轻量型网片与重量型网片的远期临床疗效及安全性。方法计算机检索Pub Med、EMBASE、The Cochrane图书馆、Web of Science、中国生物医学文献数据库、中国期刊全文数据库、万方数字化期刊群和维普中文科技期刊数据库,检索时间均从建库至2013年11月,同时追溯纳入文献的参考文献。由两名评价者按照纳入与排除标准以及Cochrane协作网推荐的方法独立筛选文献、提取资料并评价纳入研究的方法学质量后,采用Rev Man 5.2.5软件进行Meta分析。结果共纳入15个随机对照试验,包含3 390例患者。Meta分析结果显示:与重量型网片相比,轻量型网片可减轻术后近期(≤12个月)慢性疼痛[6个月:相对危险度0.67,95%可信区间(0.53,0.83),P=0.000 3;12个月:相对危险度0.79,95%可信区间(0.64,0.98),P=0.03]和术后异物感[相对危险度0.69,95%可信区间(0.56,0.85),P=0.000 5];而在术后远期(>12个月)疼痛[相对危险度0.93,95%可信区间(0.72,1.19),P=0.56]、复发[相对危险度1.21,95%可信区间(0.77,1.90),P=0.41]和睾丸萎缩[相对危险度1.90,95%可信区间(0.58,6.28),P=0.29]的发生率方面差异无统计学意义。结论与重量型网片相比,轻量型网片可降低术后短期慢性疼痛并减少异物感,且未增加复发。在腹股沟疝修补术中,可以将轻量型网片作为首选。展开更多
基金Research and Development of Anti-adhesion Hernia Patch,China(No.2016YFB0303300-03)
文摘The traditional synthetic polypropylene(PP) meshes for hernia surgical repair were controversial due to increasing postoperative complications,including chronic pain,infection and shrinkage.These morbidities may be related to a mismatch of mechanical properties between abdominal wall and the meshes.The aims of this study were to design a large pore,lightweight and anisotropic hernia mesh material and explore the influence of pulling density on mechanical properties of experimental hernia mesh materials.The hernia mesh material included A,B,and C samples knitted by RS4 EL warp knitting machine with 16 E gauge.The results showed that the mechanical properties of hernia mesh materials met the requirement of anisotropy in abdominal wall tissue.With the pulling density increased,bursting strength,uniaxial tensile strength and suture pulling out force tended to increase,while tearing force was no significant difference.Sample C showed superior physical and mechanical properties.
文摘目的评价Lichtenstein腹股沟疝修补术中轻量型网片与重量型网片的远期临床疗效及安全性。方法计算机检索Pub Med、EMBASE、The Cochrane图书馆、Web of Science、中国生物医学文献数据库、中国期刊全文数据库、万方数字化期刊群和维普中文科技期刊数据库,检索时间均从建库至2013年11月,同时追溯纳入文献的参考文献。由两名评价者按照纳入与排除标准以及Cochrane协作网推荐的方法独立筛选文献、提取资料并评价纳入研究的方法学质量后,采用Rev Man 5.2.5软件进行Meta分析。结果共纳入15个随机对照试验,包含3 390例患者。Meta分析结果显示:与重量型网片相比,轻量型网片可减轻术后近期(≤12个月)慢性疼痛[6个月:相对危险度0.67,95%可信区间(0.53,0.83),P=0.000 3;12个月:相对危险度0.79,95%可信区间(0.64,0.98),P=0.03]和术后异物感[相对危险度0.69,95%可信区间(0.56,0.85),P=0.000 5];而在术后远期(>12个月)疼痛[相对危险度0.93,95%可信区间(0.72,1.19),P=0.56]、复发[相对危险度1.21,95%可信区间(0.77,1.90),P=0.41]和睾丸萎缩[相对危险度1.90,95%可信区间(0.58,6.28),P=0.29]的发生率方面差异无统计学意义。结论与重量型网片相比,轻量型网片可降低术后短期慢性疼痛并减少异物感,且未增加复发。在腹股沟疝修补术中,可以将轻量型网片作为首选。
