Synthesis, Crystal Structure and Anti-lung Cancer Activity of a New Dy(Ⅱ) Complex

A new Dy-based coordination polymer, namely {[Dy（cptpy）_2（H_2O）_2]（TPT）（Cl）}_n（1, Hcptpy = 4-（4-carboxyphenyl）-4,2？：6？,4？？-terpyridine, TPT = 2,4,6-tri（4-pyridyl）-1,3,5-triazine, DMA = N,N-dimethylacetamide） has been solvothermally synthesized by the reactions of DyCl_3, Hcptpy and TPT in a mixture solvent of DMA and H_2O. Single-crystal X-ray structural analysis reveals that 1 is a 1D linear chain coordination polymer with quadrangle channels which are occupied by the TPT ligands. The compound has been characterized by singe-crystal analyses, thermogravimetry analyses and powder X-ray diffraction measurements. The antitumor activity of compound 1 and its corresponding organic ligands Hcptpy and TPT were then investigated against four human lung cancer cell lines（NCI-H460, Calu-3, A549 and NCI-H292） by MTT assay. It was found that compared with Hcptpy and TPT, compound 1 exerted rather potent activity against all of these cell lines.

Differences in Crystallization Behaviors between Cyclic and Linear Polymer Nanocomposites

Cyclic polymers exhibit fascinating crystallization behaviors owing to the absence of chain ends and more compact conformations.In the current simulation,dynamic Monte Carlo simulations were performed to reveal the underlying mechanism of the effect of chain topology and chain length on crystallization of polymer in solutions containing one-dimensional nanofiller.Simulation results suggested that the filled cyclic polymers exhibit higher melting temperature,higher crystallization temperature,and faster crystallization rate than the analogous linear polymers of identical chain length,especially in the systems with relatively short chains.Based on the Thomson-Gibbs equation,we theoretically analyzed the difference in the melting point between the cyclic and linear polymers under different chain lengths,and derived the dependence of the ratio of the melting point of the linear polymers to that of its cyclic analogs on chain length.In addition,it was also observed that the nanofiller can induce the formation of nanohybrid shish-kebab structure during isothermal crystallization of all systems.

[5]Rotaxane, linear polymer and supramolecular organic framework constructed by nor-seco-cucurbit[10]uril-based ternary complexation

Here we use nor-seco-cucurbit[10]uril(ns-CB[10]) based ternary complexation to construct [5]rotaxane,linear supramolecular dynamic rotaxane polymers and cubic 3D supramolecular organic framework.A [5]rotaxane is constructed by ns-CB[10], TMe CB[6] and short linear derivatives of 4,4'-bipyridinium(M2). ns-CB[10], CB[7] and long linear derivatives of 4,4'-bipyridinium(M3) self-assemble into a linear supramolecular dynamic rotaxane polymer. ns-CB[10] and tetracationic tetrahedral monomer selfassemble and form a three-dimensional supramolecular organic framework. The above results demonstrate that ns-CB[10]-based ternary complexation is a versatile platform to build various supramolecular systems.