A chemoenzymatic approach was applied to the preparation of chiral 3-hydroxy-3-arylpropionates and 3-hydroxy-4,4,4-trifluorobutanoate that are potential precursors for certain chiral pharmaceuticals including chiral ...A chemoenzymatic approach was applied to the preparation of chiral 3-hydroxy-3-arylpropionates and 3-hydroxy-4,4,4-trifluorobutanoate that are potential precursors for certain chiral pharmaceuticals including chiral tomoxetines and fluoxetines.展开更多
基金Project supported by the National Natural Science Foundation of China (Nos. 20272075 and 20372076).
文摘A chemoenzymatic approach was applied to the preparation of chiral 3-hydroxy-3-arylpropionates and 3-hydroxy-4,4,4-trifluorobutanoate that are potential precursors for certain chiral pharmaceuticals including chiral tomoxetines and fluoxetines.