Low light stress is one of the most important factors affecting photosynthesis and growth in winter production of cucumber (Cucumis sativus L.) in solar greenhouses in northern China. Here, two genotypes of cucumber...Low light stress is one of the most important factors affecting photosynthesis and growth in winter production of cucumber (Cucumis sativus L.) in solar greenhouses in northern China. Here, two genotypes of cucumber (Deltastar and Jinyan 2) are used to determine the effect of low light stress on Rubisco expression and photosynthesis of leaves from emergence to senescence. During leaf development, the net photosynthetic rate (PN), stomatal conductance (gs), Rubisco initial activity and activation state, transcript levels of rbcL and rbcS, and the abundance of rbcL and rbcS DNA in these two genotypes increase rapidly to reach maximum in 10-20 d, and then decrease gradually. Meanwhile, the actual photosystem II efficiency (OpSll) of cucumber leaves slowly increased in the early leaf developing stages, but it declined quickly in leaf senescent stages, accompanied by an increased non-photochemical quenching (NPQ). Moreover, PN, gs, initial Rubisco activity, and abundance of protein, mRNA and DNA of Rubisco subunits of leaves grown under 100 μmol m^-2 s^-1 are lower, and require more time to reach their maxima than those grown under 600 μmol m^-2 s^-1 during leaf development. All these results suggest that lower photosynthetic capacity of cucumber leaves from emergence to senescence under low light stress is probably due to down-regulated Rubisco gene expression in transcript and protein levels, and decreased initial and total activity as well as activation state of Rubisco. Deltastar performs better than Jinyan 2 under low light stress.展开更多
Low gravity fields have been simulated through magnetic acceleration to conduct experimental study on bearing capacity of circular footings on a type of crushable planetary regolith simulant,which has comparable densi...Low gravity fields have been simulated through magnetic acceleration to conduct experimental study on bearing capacity of circular footings on a type of crushable planetary regolith simulant,which has comparable density and particle size distribution of lunar soil.The loadesettlement responses of surface spread footings are obtained by investigating the relative density,footing size and gravity effects.Applying the hyperbolic asymptote method,normalised foundation stiffness and ultimate bearing capacity are obtained by curve fitting and predicted by power functions using multivariate nonlinear regression.The results show that the nonlinear gravity effect is not negligible,related to stress condition,soil dilatancy and mobilised friction angle.A cone penetration test(CPT)-based method for prediction of bearing capacity is proposed with correlations between ultimate bearing capacity of footings and shallow penetration stiffness of CPTs,avoiding the uncertainties of soil property estimations.Analyses of allowable bearing capacity and footing influence zone in consideration of footing size and gravity effects could therefore improve the design of shallow foundations on the Moon and Mars,and provide new understandings and potential implications to the bearing capacity of shallow foundations on crushable granular material in both terrestrial and extraterrestrial geotechnical engineering.展开更多
The low-temperature heat capacities are studied for antiperovskite compounds AX M_3(A = Al, Ga, Cu, Ag, Sn, X = C,N, M = Mn, Fe, Co). A large peak in(C- γ T)/T^3 versus T is observed for each of a total of 18 com...The low-temperature heat capacities are studied for antiperovskite compounds AX M_3(A = Al, Ga, Cu, Ag, Sn, X = C,N, M = Mn, Fe, Co). A large peak in(C- γ T)/T^3 versus T is observed for each of a total of 18 compounds investigated,indicating an existence of low-energy phonon mode unexpected by Debye T^3 law. Such a peak is insensitive to the external magnetic field up to 80 k Oe(1 Oe = 79.5775 A·m-1). For compounds with smaller lattice constant, the peak shifts towards higher temperatures with a reduction of peak height. This abnormal peak in(C- γ T)/T^3 versus T of antiperovskite compound may result from the strongly dispersive acoustic branch due to the heavier A atoms and the optical-like mode from the dynamic rotation of X M_6 octahedron. Such a low-energy phonon mode may not contribute negatively to the normal thermal expansion in AX M_3 compounds, while it is usually concomitant with negative thermal expansion in open-structure material(e.g., ZrW_2O_8, Sc F_3).展开更多
This paper reports that the low-temperature heat capacities of pyridine-2,6-dicarboxylic acid were measured by a precision automatic calorimeter over a temperature range from 78 K to 380 K. A polynomial equation of he...This paper reports that the low-temperature heat capacities of pyridine-2,6-dicarboxylic acid were measured by a precision automatic calorimeter over a temperature range from 78 K to 380 K. A polynomial equation of heat capacities as a function of temperature was fitted by the least-squares method. Based on the fitted polynomial, the smoothed heat capacities and thermodynamic functions of the compound relative to the standard reference temperature 298.15 K were calculated and tabulated at intervals of 5 K. The constant-volume energy of combustion of the compound was determined by means of a precision rotating-bomb combustion calorimeter. The standard molar enthalpy of combustion of the compound was derived from the constant-volume energy of combustion. The standard molar enthalpy of formation of the compound was calculated from a combination of the datum of the standard molar enthalpy of combustion of the compound with other auxiliary thermodynamic quantities through a Hess thermochemical cycle.展开更多
Cardiac rehabilitation is recommended for patients with chronic heart failure (CHF) with preserved, or reduced left ventricular ejection fraction (LVEF). A cardiac rehabilitation program generally includes physical ex...Cardiac rehabilitation is recommended for patients with chronic heart failure (CHF) with preserved, or reduced left ventricular ejection fraction (LVEF). A cardiac rehabilitation program generally includes physical exercise, diet counseling, educational classes on lifestyle changes, and disease management as well as psychosocial support for patients and their families. Exercise training is a core component of the comprehensive cardiac rehabilitation program and is strongly recommended in combination with pharmacological treatment to patients with CHF, due to cardiorespiratory, metabolic, and autonomic cardiac response. Exercise-based cardiac rehabilitation affects positively functional capacity, exercise tolerance, and quality of life in CHF patients. The physical inactivity rate in Arabian Peninsula countries is extremely high, and exercise training of habitually physically inactive individuals should result in marked improvements of physical capacity. We present a case that demonstrates such a significant improvement in the physical capacity of a patient with CHF and a review of literature.展开更多
This paper reports that low-temperature heat capacities of 4-(2-aminoethyl)-phenol (C8H11NO) are measured by a precision automated adiabatic calorimeter over the temperature range from 78 to 400 K. A polynomial eq...This paper reports that low-temperature heat capacities of 4-(2-aminoethyl)-phenol (C8H11NO) are measured by a precision automated adiabatic calorimeter over the temperature range from 78 to 400 K. A polynomial equation of heat capacities as a function of the temperature was fitted by the least square method. Based on the fitted polynomial, the smoothed heat capacities and thermodynamic functions of the compound relative to the standard reference temperature 298.15K were calculated and tabulated at the interval of 5K. The energy equivalent, εcalor, of the oxygen-bomb combustion calorimeter has been determined from 0.68g of NIST 39i benzoic acid to be εcalor=(14674.69±17.49)J·K^-1. The constant-volume energy of combustion of the compound at T=298.15 K was measured by a precision oxygen-bomb combustion calorimeter to be ΔcU=-(32374.25±12.93)J·g^-1. The standard molar enthalpy of combustion for the compound was calculated to be ΔcHm = -(4445.47 ± 1.77) kJ·mol^-1 according to the definition of enthalpy of combustion and other thermodynamic principles. Finally, the standard molar enthalpy of formation of the compound was derived to be ΔfHm(C8H11NO, s)=-(274.68 ±2.06) kJ·mol^-1, in accordance with Hess law.展开更多
Low-temperature heat capacities of the solid compound Zn(C4H7O5)2(s) were measured in a temperature range from 78 to 374 K, with an automated adiabatic calorimeter. A solid-to-solid phase transition occurred in th...Low-temperature heat capacities of the solid compound Zn(C4H7O5)2(s) were measured in a temperature range from 78 to 374 K, with an automated adiabatic calorimeter. A solid-to-solid phase transition occurred in the temperature range of 295?322 K. The peak temperature, the enthalpy, and entropy of the phase transition were determined to be (316.269±1.039) K, (11.194±0.335) kJ?mol-1, and (35.391±0.654) J?K-1?mol-1, respectively. The experimental values of the molar heat capacities in the temperature regions of 78?295 K and 322?374 K were fitted to two polynomial equations of heat capacities(Cp,m) with reduced temperatures(X) and [X = f(T)], with the help of the least squares method, respectively. The smoothed molar heat capacities and thermodynamic functions of the compound, relative to that of the standard reference temperature 293.15 K, were calculated on the basis of the fitted polynomials and tabulated with an interval of 5 K. In addition, the possible mechanism of thermal decomposition of the compound was inferred by the result of TG-DTG analysis.展开更多
Economic development has brought about global greenhouse gas emissions, which in turn has brought about global climate change. This research paper aims to compare the strengths and weaknesses that China has demonstrat...Economic development has brought about global greenhouse gas emissions, which in turn has brought about global climate change. This research paper aims to compare the strengths and weaknesses that China has demonstrated in the implementation of its low-carbon city strategy and to summarise the valuable experience that China can provide to the world in the implementation of its low-carbon city strategy. This essay analyses in depth the advantages that China has shown in the areas of renewable energy use and government mechanisms, as well as the shortcomings that it has shown in the areas of eco-efficiency industrial structure and capacity upgrading. Then, the paper summarises the successful experiences of the Chinese government in the establishment of renewable energy use and governmental mechanisms, such as the local government’s ability to coordinate multiple sectors (industrial sector, energy sector, etc.) and the implementation of responsibilities. In comparison, the paper also further discusses that China’s implementation of a low-carbon strategy in the future may have more eco-efficiency, industrial structure and capacity upgrading.展开更多
In connection with the current prospect of decarbonization of coal energy through the use of small nuclear power plants (SNPPs) at existing TPPs as heat sources for heat supply to municipal heating networks, there is ...In connection with the current prospect of decarbonization of coal energy through the use of small nuclear power plants (SNPPs) at existing TPPs as heat sources for heat supply to municipal heating networks, there is a technological need to improve heat supply schemes to increase their environmental friendliness and efficiency. The paper proves the feasibility of using the heat-feeding mode of ASHPs for urban heat supply by heating the network water with steam taken from the turbine. The ratio of electric and thermal power of a “nuclear” combined heat and power plant is given. The advantage of using a heat pump, which provides twice as much electrical power with the same heat output, is established. Taking into account that heat in these modes is supplied with different potential, the energy efficiency was used to compare these options. To increase the heat supply capacity, a scheme with the use of a high-pressure heater in the backpressure mode and with the heating of network water with hot steam was proposed. Heat supply from ASHPs is efficient and environmentally friendly even in the case of significant remoteness of heat consumers.展开更多
Introduction:As the epidemic of non-communicable diseases(NCDs)is rapidly developing in low and middleincome countries(LMICs),the importance of local research capacity and the role of contextually relevant research in...Introduction:As the epidemic of non-communicable diseases(NCDs)is rapidly developing in low and middleincome countries(LMICs),the importance of local research capacity and the role of contextually relevant research in informing policy and practice is of paramount importance.In this regard,initiatives in research capacity strengthening(RCS)are very important.The aim of this study was to review and summarize NCD research capacity strengthening strategies that have been undertaken in LMICs.Methods:Using both systematic and other literature search,we identified and reviewed NCD-RCS initiatives that have been implemented in LMICs and reported since 2000.Information was extracted from published papers and websites related to these initiatives using a semi-structured checklist.We extracted information on program design,stakeholders involved,and countries of focus,program duration,targeted researchers,disease focus,skill/capacity areas involved and sources of funding.The extracted information was refined through further review and then underwent a textual narrative synthesis.Results:We identified a number of different strategies used by research capacity strengthening programs and in the majority of initiatives,a combination of approaches was utilized.Capacity strengthening and training approaches were variously adapted locally and tailored to fit with the identified needs of the targeted researchers and health professionals.Most initiatives focused on individual level capacity and not system level capacity,although some undoubtedly benefited the research and health systems of LMICs.For most initiatives,mid-term and long-term outcomes were not evaluated.Though these initiatives might have enhanced research capacity in the immediate term,the sustainability of the results in the long-term remains unknown.Conclusion:Most of NCD-RCS initiatives in LMICs focused on building individual capacity and only a few focused explicitly on institutional level capacity strengthening.Though many of the initiatives appear to have had promising short-term outcomes,evidence on their long-term impact and sustainability is lacking.展开更多
BACKGROUND While Crohn’s disease has been studied extensively in high-income countries,its epidemiology and care in low and lower-middle income countries(LLMICs)is not well established due to a lack of disease regist...BACKGROUND While Crohn’s disease has been studied extensively in high-income countries,its epidemiology and care in low and lower-middle income countries(LLMICs)is not well established due to a lack of disease registries and diagnostic capacity.AIM To describe the published burden,diagnostic/treatment capacity,service utilization,challenges/barriers to individuals with Crohn’s in LLMICs and their providers.METHODS We conducted a scoping review utilizing a full search strategy was developed and conducted in PubMed,Embase and World Health Organization Global Index Medicus.Two independent reviewers screened the titles and abstracts of all of the publications found in this search,reviewed selected publications,and extracted relevant data,which underwent descriptive review and was analyzed in Excel.RESULTS The database search yielded 4486 publications,216 of which were determined to be relevant to the research questions.Of all 79 LLMICs,only 21(26.6%)have publications describing individuals with Crohn’s.Overall,the highest number of studies came from India,followed by Tunisia,and Egypt.The mean number of Crohn’s patients reported per study is 57.84 and the median is 22,with a wide range from one to 980.CONCLUSION This scoping review has shown that,although there is a severe lack of populationbased data about Crohn’s in LLMICs,there is a signal of Crohn’s in these settings around the world.展开更多
Companies bear primary responsibility for low-carbon economy,thus relevant low-carbon policies should be set properly to guide them and to ensure their low-carbon production effectively.To solve the problems generated...Companies bear primary responsibility for low-carbon economy,thus relevant low-carbon policies should be set properly to guide them and to ensure their low-carbon production effectively.To solve the problems generated during low-carbon development,this article verifies the existence of the transmission path and strength.This verification includes mediating variables of companies'willingness and capacity to conduct low-carbon production,a transmission mechanism through incentive path and resources protection,and questionnaire data of agricultural companies.Conclusions show that the lowcarbon policies have obvious positive effects on willingness of corporation;the basic service-oriented policy has a significantly promoting effect on low-carbon production capacity;and low-carbon production performance is positively influenced by willingness as well as capability.Aiming at a better transmission path,some corresponding recommendations have been put forward in the end.展开更多
基金supported by China Agriculture Research System (CARS-25)the National Basic Research Program of China (973 Program, 2009CB11900)the National Key Technologies R&D Program of China (2011BAD12B01)
文摘Low light stress is one of the most important factors affecting photosynthesis and growth in winter production of cucumber (Cucumis sativus L.) in solar greenhouses in northern China. Here, two genotypes of cucumber (Deltastar and Jinyan 2) are used to determine the effect of low light stress on Rubisco expression and photosynthesis of leaves from emergence to senescence. During leaf development, the net photosynthetic rate (PN), stomatal conductance (gs), Rubisco initial activity and activation state, transcript levels of rbcL and rbcS, and the abundance of rbcL and rbcS DNA in these two genotypes increase rapidly to reach maximum in 10-20 d, and then decrease gradually. Meanwhile, the actual photosystem II efficiency (OpSll) of cucumber leaves slowly increased in the early leaf developing stages, but it declined quickly in leaf senescent stages, accompanied by an increased non-photochemical quenching (NPQ). Moreover, PN, gs, initial Rubisco activity, and abundance of protein, mRNA and DNA of Rubisco subunits of leaves grown under 100 μmol m^-2 s^-1 are lower, and require more time to reach their maxima than those grown under 600 μmol m^-2 s^-1 during leaf development. All these results suggest that lower photosynthetic capacity of cucumber leaves from emergence to senescence under low light stress is probably due to down-regulated Rubisco gene expression in transcript and protein levels, and decreased initial and total activity as well as activation state of Rubisco. Deltastar performs better than Jinyan 2 under low light stress.
基金The authors wish to thank the support from the‘Double Tops’Construction Independent Innovation Project of China University of Mining and Technology(Grant No.2018ZZCX04).
文摘Low gravity fields have been simulated through magnetic acceleration to conduct experimental study on bearing capacity of circular footings on a type of crushable planetary regolith simulant,which has comparable density and particle size distribution of lunar soil.The loadesettlement responses of surface spread footings are obtained by investigating the relative density,footing size and gravity effects.Applying the hyperbolic asymptote method,normalised foundation stiffness and ultimate bearing capacity are obtained by curve fitting and predicted by power functions using multivariate nonlinear regression.The results show that the nonlinear gravity effect is not negligible,related to stress condition,soil dilatancy and mobilised friction angle.A cone penetration test(CPT)-based method for prediction of bearing capacity is proposed with correlations between ultimate bearing capacity of footings and shallow penetration stiffness of CPTs,avoiding the uncertainties of soil property estimations.Analyses of allowable bearing capacity and footing influence zone in consideration of footing size and gravity effects could therefore improve the design of shallow foundations on the Moon and Mars,and provide new understandings and potential implications to the bearing capacity of shallow foundations on crushable granular material in both terrestrial and extraterrestrial geotechnical engineering.
基金Project supported by the National Key Basic Research Program of China(Grant Nos.2011CBA00111)the National Natural Science Foundation of China(Grant Nos.51322105,U1632158,51301165,and 51301167)
文摘The low-temperature heat capacities are studied for antiperovskite compounds AX M_3(A = Al, Ga, Cu, Ag, Sn, X = C,N, M = Mn, Fe, Co). A large peak in(C- γ T)/T^3 versus T is observed for each of a total of 18 compounds investigated,indicating an existence of low-energy phonon mode unexpected by Debye T^3 law. Such a peak is insensitive to the external magnetic field up to 80 k Oe(1 Oe = 79.5775 A·m-1). For compounds with smaller lattice constant, the peak shifts towards higher temperatures with a reduction of peak height. This abnormal peak in(C- γ T)/T^3 versus T of antiperovskite compound may result from the strongly dispersive acoustic branch due to the heavier A atoms and the optical-like mode from the dynamic rotation of X M_6 octahedron. Such a low-energy phonon mode may not contribute negatively to the normal thermal expansion in AX M_3 compounds, while it is usually concomitant with negative thermal expansion in open-structure material(e.g., ZrW_2O_8, Sc F_3).
基金Project supported by the National Natural Science Foundations of China (Grant Nos.20673050 and 20973089)
文摘This paper reports that the low-temperature heat capacities of pyridine-2,6-dicarboxylic acid were measured by a precision automatic calorimeter over a temperature range from 78 K to 380 K. A polynomial equation of heat capacities as a function of temperature was fitted by the least-squares method. Based on the fitted polynomial, the smoothed heat capacities and thermodynamic functions of the compound relative to the standard reference temperature 298.15 K were calculated and tabulated at intervals of 5 K. The constant-volume energy of combustion of the compound was determined by means of a precision rotating-bomb combustion calorimeter. The standard molar enthalpy of combustion of the compound was derived from the constant-volume energy of combustion. The standard molar enthalpy of formation of the compound was calculated from a combination of the datum of the standard molar enthalpy of combustion of the compound with other auxiliary thermodynamic quantities through a Hess thermochemical cycle.
文摘Cardiac rehabilitation is recommended for patients with chronic heart failure (CHF) with preserved, or reduced left ventricular ejection fraction (LVEF). A cardiac rehabilitation program generally includes physical exercise, diet counseling, educational classes on lifestyle changes, and disease management as well as psychosocial support for patients and their families. Exercise training is a core component of the comprehensive cardiac rehabilitation program and is strongly recommended in combination with pharmacological treatment to patients with CHF, due to cardiorespiratory, metabolic, and autonomic cardiac response. Exercise-based cardiac rehabilitation affects positively functional capacity, exercise tolerance, and quality of life in CHF patients. The physical inactivity rate in Arabian Peninsula countries is extremely high, and exercise training of habitually physically inactive individuals should result in marked improvements of physical capacity. We present a case that demonstrates such a significant improvement in the physical capacity of a patient with CHF and a review of literature.
基金supported by the National Natural Science Foundation of China (Grant No 20673050)
文摘This paper reports that low-temperature heat capacities of 4-(2-aminoethyl)-phenol (C8H11NO) are measured by a precision automated adiabatic calorimeter over the temperature range from 78 to 400 K. A polynomial equation of heat capacities as a function of the temperature was fitted by the least square method. Based on the fitted polynomial, the smoothed heat capacities and thermodynamic functions of the compound relative to the standard reference temperature 298.15K were calculated and tabulated at the interval of 5K. The energy equivalent, εcalor, of the oxygen-bomb combustion calorimeter has been determined from 0.68g of NIST 39i benzoic acid to be εcalor=(14674.69±17.49)J·K^-1. The constant-volume energy of combustion of the compound at T=298.15 K was measured by a precision oxygen-bomb combustion calorimeter to be ΔcU=-(32374.25±12.93)J·g^-1. The standard molar enthalpy of combustion for the compound was calculated to be ΔcHm = -(4445.47 ± 1.77) kJ·mol^-1 according to the definition of enthalpy of combustion and other thermodynamic principles. Finally, the standard molar enthalpy of formation of the compound was derived to be ΔfHm(C8H11NO, s)=-(274.68 ±2.06) kJ·mol^-1, in accordance with Hess law.
基金the National Natural Science Foundation of China(No.20673050).
文摘Low-temperature heat capacities of the solid compound Zn(C4H7O5)2(s) were measured in a temperature range from 78 to 374 K, with an automated adiabatic calorimeter. A solid-to-solid phase transition occurred in the temperature range of 295?322 K. The peak temperature, the enthalpy, and entropy of the phase transition were determined to be (316.269±1.039) K, (11.194±0.335) kJ?mol-1, and (35.391±0.654) J?K-1?mol-1, respectively. The experimental values of the molar heat capacities in the temperature regions of 78?295 K and 322?374 K were fitted to two polynomial equations of heat capacities(Cp,m) with reduced temperatures(X) and [X = f(T)], with the help of the least squares method, respectively. The smoothed molar heat capacities and thermodynamic functions of the compound, relative to that of the standard reference temperature 293.15 K, were calculated on the basis of the fitted polynomials and tabulated with an interval of 5 K. In addition, the possible mechanism of thermal decomposition of the compound was inferred by the result of TG-DTG analysis.
文摘Economic development has brought about global greenhouse gas emissions, which in turn has brought about global climate change. This research paper aims to compare the strengths and weaknesses that China has demonstrated in the implementation of its low-carbon city strategy and to summarise the valuable experience that China can provide to the world in the implementation of its low-carbon city strategy. This essay analyses in depth the advantages that China has shown in the areas of renewable energy use and government mechanisms, as well as the shortcomings that it has shown in the areas of eco-efficiency industrial structure and capacity upgrading. Then, the paper summarises the successful experiences of the Chinese government in the establishment of renewable energy use and governmental mechanisms, such as the local government’s ability to coordinate multiple sectors (industrial sector, energy sector, etc.) and the implementation of responsibilities. In comparison, the paper also further discusses that China’s implementation of a low-carbon strategy in the future may have more eco-efficiency, industrial structure and capacity upgrading.
文摘In connection with the current prospect of decarbonization of coal energy through the use of small nuclear power plants (SNPPs) at existing TPPs as heat sources for heat supply to municipal heating networks, there is a technological need to improve heat supply schemes to increase their environmental friendliness and efficiency. The paper proves the feasibility of using the heat-feeding mode of ASHPs for urban heat supply by heating the network water with steam taken from the turbine. The ratio of electric and thermal power of a “nuclear” combined heat and power plant is given. The advantage of using a heat pump, which provides twice as much electrical power with the same heat output, is established. Taking into account that heat in these modes is supplied with different potential, the energy efficiency was used to compare these options. To increase the heat supply capacity, a scheme with the use of a high-pressure heater in the backpressure mode and with the heating of network water with hot steam was proposed. Heat supply from ASHPs is efficient and environmentally friendly even in the case of significant remoteness of heat consumers.
基金funded by the Fogarty International Centre(FIC)of the National Institutes of Health(NIH)under Award Number:D43TW008332.
文摘Introduction:As the epidemic of non-communicable diseases(NCDs)is rapidly developing in low and middleincome countries(LMICs),the importance of local research capacity and the role of contextually relevant research in informing policy and practice is of paramount importance.In this regard,initiatives in research capacity strengthening(RCS)are very important.The aim of this study was to review and summarize NCD research capacity strengthening strategies that have been undertaken in LMICs.Methods:Using both systematic and other literature search,we identified and reviewed NCD-RCS initiatives that have been implemented in LMICs and reported since 2000.Information was extracted from published papers and websites related to these initiatives using a semi-structured checklist.We extracted information on program design,stakeholders involved,and countries of focus,program duration,targeted researchers,disease focus,skill/capacity areas involved and sources of funding.The extracted information was refined through further review and then underwent a textual narrative synthesis.Results:We identified a number of different strategies used by research capacity strengthening programs and in the majority of initiatives,a combination of approaches was utilized.Capacity strengthening and training approaches were variously adapted locally and tailored to fit with the identified needs of the targeted researchers and health professionals.Most initiatives focused on individual level capacity and not system level capacity,although some undoubtedly benefited the research and health systems of LMICs.For most initiatives,mid-term and long-term outcomes were not evaluated.Though these initiatives might have enhanced research capacity in the immediate term,the sustainability of the results in the long-term remains unknown.Conclusion:Most of NCD-RCS initiatives in LMICs focused on building individual capacity and only a few focused explicitly on institutional level capacity strengthening.Though many of the initiatives appear to have had promising short-term outcomes,evidence on their long-term impact and sustainability is lacking.
文摘BACKGROUND While Crohn’s disease has been studied extensively in high-income countries,its epidemiology and care in low and lower-middle income countries(LLMICs)is not well established due to a lack of disease registries and diagnostic capacity.AIM To describe the published burden,diagnostic/treatment capacity,service utilization,challenges/barriers to individuals with Crohn’s in LLMICs and their providers.METHODS We conducted a scoping review utilizing a full search strategy was developed and conducted in PubMed,Embase and World Health Organization Global Index Medicus.Two independent reviewers screened the titles and abstracts of all of the publications found in this search,reviewed selected publications,and extracted relevant data,which underwent descriptive review and was analyzed in Excel.RESULTS The database search yielded 4486 publications,216 of which were determined to be relevant to the research questions.Of all 79 LLMICs,only 21(26.6%)have publications describing individuals with Crohn’s.Overall,the highest number of studies came from India,followed by Tunisia,and Egypt.The mean number of Crohn’s patients reported per study is 57.84 and the median is 22,with a wide range from one to 980.CONCLUSION This scoping review has shown that,although there is a severe lack of populationbased data about Crohn’s in LLMICs,there is a signal of Crohn’s in these settings around the world.
文摘Companies bear primary responsibility for low-carbon economy,thus relevant low-carbon policies should be set properly to guide them and to ensure their low-carbon production effectively.To solve the problems generated during low-carbon development,this article verifies the existence of the transmission path and strength.This verification includes mediating variables of companies'willingness and capacity to conduct low-carbon production,a transmission mechanism through incentive path and resources protection,and questionnaire data of agricultural companies.Conclusions show that the lowcarbon policies have obvious positive effects on willingness of corporation;the basic service-oriented policy has a significantly promoting effect on low-carbon production capacity;and low-carbon production performance is positively influenced by willingness as well as capability.Aiming at a better transmission path,some corresponding recommendations have been put forward in the end.