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Scedosporium apiospermum infection of the lumbar vertebrae:A case report 被引量:1
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作者 Xue-Wen Shi Sheng-Tang Li +7 位作者 Jin-Peng Lou Bo Xu Jian Wang Xin Wang Hua Liu Song-Kai Li Ping Zhen Tao Zhang 《World Journal of Clinical Cases》 SCIE 2022年第10期3251-3260,共10页
BACKGROUND Scedosporium apiospermum(S.apiospermum)is a clinically rare and aggressive fungus mainly found in contaminated water,wetlands,decaying plants,stagnant water,and potted plants in hospitals.The lung,bone,join... BACKGROUND Scedosporium apiospermum(S.apiospermum)is a clinically rare and aggressive fungus mainly found in contaminated water,wetlands,decaying plants,stagnant water,and potted plants in hospitals.The lung,bone,joint,eye,brain,skin,and other sites are easily infected,and there is a marked risk of misdiagnosis.There have been few case reports of infection by S.apiospermum of the lumbar vertebrae;most reports have focused on infection of the lung.CASE SUMMARY An otherwise healthy 60-year-old man presented with a 4-mo history of lumbosacral pain,stooping,and limited walking.The symptoms were significantly aggravated 10 d prior to hospitalization,and radiating pain in the back of his left lower leg developed,which was so severe that he could not walk.Movement of the lumbar spine was significantly limited,anterior flexion was about 30°;backward extension,right and left lateral curvature,and rotational mobility were about 10°;tenderness of the spinous processes of the lumbar 3-5 vertebrae was evident,and the muscle strength of both lower limbs was gradeⅣ.Imaging suggested bony destruction of the lumbar 3,4,and 5 vertebrae and sacral 1 vertebra;in addition,the corresponding intervertebral spaces were narrowed and the lumbar 5 vertebra was posteriorly displaced and unstable.Lumbar vertebral infection was also noted,and the possibility of lumbar tuberculosis was considered.We first performed surgical intervention on the lesioned lumbar vertebrae,cleared the infected lesion,and performed stable fixation of the lesioned vertebral body using a lumbar internal fixation device,which restored the stability of the lumbar vertebrae.Cytological and pathological examination of the lesioned tissue removed during surgery confirmed S.apiospermum infection of the lumbar vertebrae;on this basis,the patient was administered voriconazole.At the 6-mo followup,efficacy was significant,no drug-related side effects were observed,and imaging examination showed no evidence of recurrence.CONCLUSION S.apiospermum infection can occur in immunocompetent individuals with no history of near drowning.Voriconazole is effective for the treatment of S.apiospermum infection of the lumbar vertebrae for which it is suitable as the first-line therapy. 展开更多
关键词 Scedosporium apiospermum lumbar vertebrae Fungal infection TREATMENT VORICONAZOLE Case report
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Cortical bone trajectory fixation in cemented vertebrae in lumbar degenerative disease:A case report
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作者 Meng-Meng Chen Pu Jia Hai Tang 《World Journal of Clinical Cases》 SCIE 2021年第28期8609-8615,共7页
BACKGROUND Percutaneous vertebroplasty(PVP)has been widely used in osteoporotic vertebral compression fracture(OVCF).Following surgery,the bone cement would be positioned permanently.However,in some cases of lumbar de... BACKGROUND Percutaneous vertebroplasty(PVP)has been widely used in osteoporotic vertebral compression fracture(OVCF).Following surgery,the bone cement would be positioned permanently.However,in some cases of lumbar degenerative disease,the cemented vertebrae needs to be fixed after decompression and fusion procedure.It is difficult to implant traditional pedicle screws into the cemented vertebrae because of the bone cement filling.At present,the main treatment strategy is to skip the cemented vertebra and conduct a long segment fixation.This article presents a cortical bone trajectory(CBT)fixation technique for cemented vertebrae.CASE SUMMARY PVP involving the L3 and L4 was performed in an 82-year-old man due to OVCF.During the surgery,bone cement leakage occurred,resulting in compression of the root of the right L3 nerve.We performed a partial facetectomy to retrieve the leaked bone cement and to relieve the patient’s neurological symptoms.After 3 mo,the patient developed lumbar disc herniation in L3/4,potentially due to instability caused by the previous surgery.Therefore,it was necessary to perform intervertebral fusion and fixation.It was difficult to implant traditional trajectory pedicle screws in L3 and L4 because of the bone cement filling.Hence,we implanted CBT screws in the L3 and L4 vertebrae.As a result,the patient’s symptoms resolved and he reported satisfaction with the surgery at follow-up after 8 mo.CONCLUSION It is feasible to utilize CBT in cemented vertebrae for the treatment of lumbar degenerative disease. 展开更多
关键词 Cortical bone trajectory Cemented vertebrae lumbar degenerative disease Spinal fixation Bone cement leakage Case report
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Surgical strategy for high-grade isthmic spondylolisthesis of 5th lumbar vertebrae
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作者 董小雄 《外科研究与新技术》 2011年第2期92-92,共1页
Objective To investigate surgical strategy for high-grade isthmic spondylolisthesis(more thanⅡ degree)of 5th lumbar vertebrae.Methods From August 2003 to October 2008,26 patients with high-grade isthmic spondylolisth... Objective To investigate surgical strategy for high-grade isthmic spondylolisthesis(more thanⅡ degree)of 5th lumbar vertebrae.Methods From August 2003 to October 2008,26 patients with high-grade isthmic spondylolisthesis (L5) were 展开更多
关键词 HIGH CAGE Surgical strategy for high-grade isthmic spondylolisthesis of 5th lumbar vertebrae
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CLINICAL OBSERVATION ON THE TREATMENT OF LUMBAR VERTEBRA HYPEROSTEOGENY WITH ELECTRO- AND HYDRO-ACUPUNCTURE 被引量:1
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作者 黄巍 茹立强 《World Journal of Acupuncture-Moxibustion》 1996年第1期37-39,共3页
In the present study, 121 patients with lumbar vertebra hyperosteogeny were dividedinto following four groups for treatment and comparison: intense electro-acupuncture group (Group1), hydro-acupuncture group (Group 2)... In the present study, 121 patients with lumbar vertebra hyperosteogeny were dividedinto following four groups for treatment and comparison: intense electro-acupuncture group (Group1), hydro-acupuncture group (Group 2), electro-acupuncture plus hydro-acupuncture group (Group3) and analgesic liquid for spur group (Group 4). It is indicated that the effect of electro-acupunctureplus hydro-acupuncture is the best in the treatment of lumbar vertebra hyperosteogeny. 展开更多
关键词 lumbar vertebra HYPEROSTEOGENY ELECTRO-ACUPUNCTURE HYDRO-ACUPUNCTURE
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Treatment of Protrusion of the Lumbar Intervertebral Disc by TCM Massage 被引量:1
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作者 龙亚军 叶环 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2002年第2期126-127,共2页
  Protrusion of the lumbar intervertebral disc is a common disorder frequently encountered in clinic. With TCM massage and the maneuver of manual reduction, we have treated 82 cases of protrusion of the lumbar inter...   Protrusion of the lumbar intervertebral disc is a common disorder frequently encountered in clinic. With TCM massage and the maneuver of manual reduction, we have treated 82 cases of protrusion of the lumbar intervertebral disc, with satisfactory therapeutic results reported in the following.…… 展开更多
关键词 腰部的 vertebrae 女性 Intervertebral 磁盘排水量 男性 按摩 拖拉
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Treatment of Protrusion of Lumbar Intervertebral Disc by Pulling and Turning Manipulations 被引量:1
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作者 刘杰 张生权 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2000年第3期195-197,共3页
The authors treated 62 cases of protrusion oflumbar intervertebral disc by pulling and turningmanipulations from February 1993 to February 1998.Another 50 cases were treated by traction as controls.Statistical data sh... The authors treated 62 cases of protrusion oflumbar intervertebral disc by pulling and turningmanipulations from February 1993 to February 1998.Another 50 cases were treated by traction as controls.Statistical data showed that pulling and turningmanipulations had much better therapeuticeffectiveness than traction(P<0.05). 展开更多
关键词 腰部的椎骨 脊椎 针灸点 成年人 女性 椎间磁盘排水量 男性 按摩 中年
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CLINICAL ANALYSIS ON TREATMENT OF LUMBAR VERTEBRAL RETROGRADE AFFECTION WITH ACUPUNCTURE,TDP-IRRADIATION AND CUPPING
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作者 周怡 《World Journal of Acupuncture-Moxibustion》 2002年第2期40-44,共5页
In the present paper, 70 cases of retrograde affection of the lumbar vertebrae are randomly and evenly divided into treatment group and control group. Shenshu (BL 23), Qihaishu (BL 24), Dachangshu (BL 25), Weizhong (B... In the present paper, 70 cases of retrograde affection of the lumbar vertebrae are randomly and evenly divided into treatment group and control group. Shenshu (BL 23), Qihaishu (BL 24), Dachangshu (BL 25), Weizhong (BL 40), Jiaji (EX B 2), etc. are used. In treatment group, acupuncture, TDP irradiation and cupping are performed, and in control group, only acupuncture is given. After 30 sessions (3 therapeutic courses) of treatment, in treatment and control groups, the total effective rates are 91.43% and 71.43% respectively. The therapeutic effect of comprehensive treatment is significantly superior to that of simple acupuncture therapy (P<0.05). 展开更多
关键词 腰椎退行性病变 针灸疗法 TDP照射
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Treatment of Protrusion of the Lumbar Intervertebral Disc by Massotherapy
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作者 程斌 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2001年第2期110-110 ,共1页
Clinically, there is a higher incidence of protrusion of the lumbar intervertebral disc. It can cause a terrible pain. The author has treated 66 cases by massotherapy, who were confirmatively diagnosed as having protr... Clinically, there is a higher incidence of protrusion of the lumbar intervertebral disc. It can cause a terrible pain. The author has treated 66 cases by massotherapy, who were confirmatively diagnosed as having protrusion of the lumbar intervertebral disc by X-ray film and computer-aided tomography, with satisfactory results as reported in the following. Clinical Data Among the 66 cases in this series, 49 were male and 17 female, ranging in age from 26 to 59 years, averaging 36.2 years. All the patients had got lumbago and unilateral ischialgia, with the left side affected in 37 cases and the right side in 29 cases. The leg pain radiating to lateral malleolus was found in 28 cases, to dorsum of the foot in 24 cases, and to the toes in 14 cases. Intermittent claudication was present in 22 cases, numbness of the affected foot in 16 cases, pain exacerbated when coughing in 35 cases, scoliosis in 21 cases, and positive Lasegue's sign in 48 cases. 展开更多
关键词 腰部的椎骨 脊椎 按摩 成年人 女性 椎间磁盘排水量 男性 中年
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The comparison of different medication project of continuous epidural analgesia for the patient after lumbar vertebra operation
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作者 王成才 袁红兵 王新华 《中国临床康复》 CSCD 2002年第4期611-611,共1页
Objective Comparing different medication pro ject of continuous epidural analgesia for the patient after lumbar verte bra opera-tion,to decrease the complications and promote analgesia effects.Methods150cases with AS... Objective Comparing different medication pro ject of continuous epidural analgesia for the patient after lumbar verte bra opera-tion,to decrease the complications and promote analgesia effects.Methods150cases with ASAⅠ~Ⅱgrade,lumbar intervertebral disc e x-tirpation and /or vertebral canal decompression,were divided into 5gro ups.A group:0.0625%bupivacaine;B group:0.125%bupiva-caine;C group:0.0625%bupivacaine and 1mg morphine;D group:0.125%bupivacaine and 1mg morphine;E group:n o analgesia.Record the occurrence of RR,MAP,HR,VAS score and side effects.Results The analgesia effects of all groups were satisfying,but the oc-currence of urine retention increased in B,C,D group,and the occurrence of nausea and vomit increased obviou sly in C,D group.Conclusions The continuous epidural analgesia w ith simple 0.0625%for patients afte r lumbar vertebral operation is best. 展开更多
关键词 腰椎手术 疼痛 连续硬膜外镇痛 药物治疗
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Fifty-six Cases of Protrusion of Lumbar Intervertebral Disc Treated by Penetration and Oral Administration of Chinese Decoction Plus Traction
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作者 钟琪 周永生 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2000年第4期273-276,共4页
Fifty-six cases of the protrusion of the lumbar intervertebral disc in the treatment group were treated by drug-penetration and oral administration of traditional Chinese decoction plus traction, and the other 35 case... Fifty-six cases of the protrusion of the lumbar intervertebral disc in the treatment group were treated by drug-penetration and oral administration of traditional Chinese decoction plus traction, and the other 35 cases in the control group by oral administration of Chinese decoction and traction. The results showed that the cure rate in the treatment group was 83.9%, and that in the control group was 57.1%, with a statistically significant difference between the two groups (P<0.01), indicating that the former is a more effective therapy for protrusion of the lumbar intervertebral disc. 展开更多
关键词 腰部的椎骨 脊椎 成年人 汉语草药 女性 椎间磁盘排水量 离子电渗疗法 男性 中年 拖拉
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Protrusion of Lumbar Intervertebral Disc Treated by Ultra Short Wave and the Point Injection in 40 Cases
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作者 张彩芳 陈正秋 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2003年第1期43-44,共2页
Since 1996,the author has treated 40 cases of protrusion of lumbar intervertebral disc with ultra short wave and the point injection,and obtained good therapeutic effects.This is reported as follows.
关键词 脊椎椎间盘突出 超短波治疗 穴位注射
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经皮椎间孔镜髓核摘除术治疗腰椎间盘突出症的疗效及对腰背肌生物力学性能、疼痛介质的影响
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作者 刘智伟 陆芳 +4 位作者 康亚娟 孔亚荣 杨朔 白晓亮 连勇 《临床和实验医学杂志》 2024年第10期1052-1056,共5页
目的研究经皮椎间孔镜髓核摘除术(PTED)治疗腰椎间盘突出症(LDH)的疗效及对腰背肌生物力学性能、疼痛介质的影响。方法前瞻性选择2020年7月至2023年6月于保定市第一中心医院接受治疗的LDH患者110例,按照随机数字表法分为PTED组(n=55)、... 目的研究经皮椎间孔镜髓核摘除术(PTED)治疗腰椎间盘突出症(LDH)的疗效及对腰背肌生物力学性能、疼痛介质的影响。方法前瞻性选择2020年7月至2023年6月于保定市第一中心医院接受治疗的LDH患者110例,按照随机数字表法分为PTED组(n=55)、对照组(n=55)。对照组行开窗减压髓核摘除术(ODD)治疗,PTED组行PTED治疗。观察两组手术时间、切口长度、术中出血量、下床时间、住院时间等围手术期指标;比较两组术前、术后3个月腰椎活动功能指标(腰椎前屈、侧屈、后伸)、脊柱功能[Oswestry功能障碍指数(ODI)]、腰背肌生物力学性能指标[腰背屈伸比(F/E)、伸展平均功率(AP)、峰力矩(PT)]、血清疼痛介质[去甲肾上腺素(NE)、P物质、五羟色胺]水平及术后并发症发生情况。结果PTED组手术时间、切口长度、术中出血量、下床时间、住院时间分别为(72.36±7.51)min、(0.82±0.09)cm、(40.06±4.24)mL、(1.32±0.15)d、(4.30±0.46)d,均短于对照组[(102.64±12.67)min、(5.23±0.55)cm、(96.09±9.84)mL、(3.79±0.39)d、(4.94±0.52)d],差异均有统计学意义(P<0.05)。术后3个月,PTED组腰椎前屈、左侧屈、右侧屈、后伸度数及PT分别为(84.65±8.73)°、(24.83±2.70)°、(25.63±2.82)°、(25.89±2.78)°、(84.67±8.72)Nm,均高于对照组[(78.94±8.01)°、(21.38±2.25)°、(22.85±2.40)°、(21.97±2.44)°、(78.85±8.21)Nm],PTED组的ODI评分、F/E、AP分别为(27.65±3.01)分、(70.48±7.34)%、(40.37±4.31)W,均低于对照组[(32.84±3.46)分、(75.26±7.80)%、(35.72±3.73)W],差异均有统计学意义(P<0.05)。PTED组血清NE、P物质、五羟色胺水平分别为(1.32±0.14)pg/mL、(52.08±5.43)ng/mL、(0.18±0.02)μmol/mL,均低于对照组[(1.68±0.19)pg/mL、(69.94±7.27)ng/mL、(0.22±0.03)μmol/mL],差异均有统计学意义(P<0.05)。PTED组术后总并发症发生率为1.82%,小于对照组(12.73%),差异有统计学意义(P<0.05)。结论PTED治疗LDH可减小手术创伤及术后并发症发生率,增强腰椎活动功能、脊柱功能,改善患者腰背肌生物力学性能,降低血清疼痛介质水平,有助于患者康复。 展开更多
关键词 腰椎生物力学 经皮椎间孔镜髓核摘除术 开窗减压髓核摘除术 腰椎间盘突出症 疼痛介质
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腰椎融合术中恢复椎间隙自然高度对手术疗效的影响
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作者 王海波 李欣 +2 位作者 王子然 卢一生 陈德纯 《脊柱外科杂志》 2024年第2期100-104,共5页
目的 探讨腰椎融合术中恢复椎间隙自然高度对手术疗效的影响。方法 测量100名健康志愿者腰椎各椎间隙高度和椎体高度,计算各椎间隙高度与椎体高度的比值及其95%置信区间(CI),并以此为正常值参考标准,将2019年6月-2021年6月接受腰椎后路... 目的 探讨腰椎融合术中恢复椎间隙自然高度对手术疗效的影响。方法 测量100名健康志愿者腰椎各椎间隙高度和椎体高度,计算各椎间隙高度与椎体高度的比值及其95%置信区间(CI),并以此为正常值参考标准,将2019年6月-2021年6月接受腰椎后路融合术治疗的133例患者根据手术节段术后椎间隙高度与椎体高度比值是否在正常值95%CI内分为自然高度组(n=78)和非自然高度组(n=55)。记录并统计2组患者术中及术后并发症发生率,采用疼痛视觉模拟量表评分(VAS)和日本骨科学会(JOA)评分评估手术前后疼痛程度及神经功能。结果 末次随访时,自然高度组发生邻椎病3例,并发症发生率为3.8%;非自然高度组发生邻椎病5例,足下垂1例,并发症发生率为10.9%;2组并发症发生率差异有统计学意义(P <0.05)。2组术后各随访时间点腰腿痛VAS评分、JOA评分较术前明显改善,末次随访时自然高度组腰腿痛VAS评分、JOA评分改善率优于非自然高度组,差异均有统计学意义(P <0.05)。结论 腰椎融合术中椎间隙的撑开高度应参照椎体自身高度,控制手术节段的椎间隙高度与椎体高度比值在正常值95%CI内可有效改善神经功能并降低并发症发生率。 展开更多
关键词 腰椎 脊柱融合术 摄影测量法 手术后并发症
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椎间隙注入不同弹性模量骨水泥对邻近上下椎体应力的影响
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作者 汪建新 霍文涛 于泽 《中国组织工程研究》 CAS 北大核心 2024年第22期3548-3554,共7页
背景:近年来,针对腰椎间盘退变和椎间隙变窄所引起的腰部反复疼痛病症从国外引入了椎间隙注入骨水泥的治疗方法,但部分患者在治疗后出现椎体骨折的情况,原因可能是骨水泥弹性模量不佳。目的:通过腰椎三维有限元模型分析椎间隙中注入不... 背景:近年来,针对腰椎间盘退变和椎间隙变窄所引起的腰部反复疼痛病症从国外引入了椎间隙注入骨水泥的治疗方法,但部分患者在治疗后出现椎体骨折的情况,原因可能是骨水泥弹性模量不佳。目的:通过腰椎三维有限元模型分析椎间隙中注入不同弹性模量骨水泥对上下椎体表面最大应力的影响。方法:招募1名脊柱正常志愿者获取CT数据,利用Mimics、Geomagic、SolidWorks、Ansys建立腰椎L_(2)-L_(5)有限元模型,随后建立L_(3)-L_(4)椎间隙注射不同剂量(1 mL与4 mL)骨水泥模型,每种剂量下赋予骨水泥4种弹性模量(1000,2000,4000,8000 MPa),在L_(2)椎体表面施加压力与弯矩,分析L_(3)椎体下表面与L_(4)椎体上表面的应力。结果与结论:①在骨水泥注入量相同的情况下,随着骨水泥弹性模量的增大,L_(3)椎体下表面与L_(4)椎体上表面的应力增加,其中弹性模量1000 MPa骨水泥对L_(3)椎体下表面与L_(4)椎体上表面的应力影响最小,弹性模量8000 MPa骨水泥对L_(3)椎体下表面与L_(4)椎体上表面的应力影响最大,不同弹性模量骨水泥对整个腰椎活动度的影响较小;②结果说明,在满足治疗要求的情况下注入较低弹性模量的骨水泥可以降低术后骨折风险。 展开更多
关键词 经皮骨水泥椎间盘成形术 腰椎 骨水泥 有限元 应力 弹性模量
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下腰椎椎体在不同负荷下屈伸运动特点的分析
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作者 宋阳 苗军 +3 位作者 冷辉 张海军 赵磊 赵雪晴 《中国医药科学》 2024年第10期170-174,共5页
目的探索不同负重状态下直立位腰椎L_(3)、L_(4)椎体屈伸运动过程中体运动轨迹,分析负重状态下腰椎在体运动的规律和特点。方法招募2018年8月至2020年8月10名无症状的青年志愿者,使用双荧光透视系统DFIS与CT相匹配技术,经平扫CT获取L_(3... 目的探索不同负重状态下直立位腰椎L_(3)、L_(4)椎体屈伸运动过程中体运动轨迹,分析负重状态下腰椎在体运动的规律和特点。方法招募2018年8月至2020年8月10名无症状的青年志愿者,使用双荧光透视系统DFIS与CT相匹配技术,经平扫CT获取L_(3)~S_(1)的图像进行三维重建。于放射线透视不同负重下0、5、10 kg完成下腰椎的前屈到直立到后伸动作获得X线影像,通过轮廓重叠实现二维到三维图像的匹配,还原下腰椎椎体的三维运动轨迹。结果下腰椎在前屈到站立位时:不同负重下腰椎椎体0、5、10 kg的X轴的运动位移分别为-1.05(-2.42,1.72)、0.63(0.15,4.26)、-0.39(-0.75,3.12)mm。X轴运动位移比较5 kg>10 kg>0 kg,差异有统计学意义(P<0.05)。γ角度分别为-0.26(-1.30,5.43)、0.93(0.24,5.42)、-0.95(-2.12,4.32)°。γ角度比较5 kg>0 kg>10 kg,差异有统计学意义(P<0.05)。下腰椎在站立到后伸位时:不同负重下腰椎椎体0、5、10 kg X轴的运动位移分别为0.90(-0.82,3.74)、-0.91(-1.55,4.26)、0.07(-0.92,3.25)mm。Z轴的运动位移分别为-0.25(-0.54,1.78)、0.40(-0.68,2.37)、-0.19(-0.92,1.03)mm。X轴运动位移比较0 kg>10 kg>5 kg,Z轴运动位移比较5 kg>10 kg>0 kg,差异有统计学意义(P<0.05)。α角度分别为0.91(-0.82,2.85)、-0.61(-0.14,3.79)、0.54(-0.82,3.87)°。γ角度分别为1.15(0.24,5.32)、0.92(-0.67,5.45)、0.65(-1.24,5.32)°。α角度比较0 kg>10 kg>5 kg,γ角度比较0 kg>5 kg>10 kg,差异有统计学意义(P<0.05)。结论负重5 kg下腰椎椎体在体运动的位移和旋转角度和0 kg相比差异有统计学意义,可能与腰椎退行性疾病有一定关联。下腰椎退行性疾病可能与X轴位移的关系更为密切。 展开更多
关键词 腰椎 在体运动 六个自由度 负重 退行性疾病
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扶阳罐循经温推联合益肾活血汤治疗腰椎间盘突出症的临床研究
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作者 彭志华 胡耶芳 赵蓉 《河北中医》 2024年第4期641-643,649,共4页
目的观察扶阳罐循经温推联合益肾活血汤治疗腰椎间盘突出症的临床疗效。方法选取2019年9月至2020年5月收治的138例腰椎间盘突出症患者为研究对象,按照随机数字表法分为2组,对照组69例采用常规推拿治疗,治疗组69例予扶阳罐循经温推联合... 目的观察扶阳罐循经温推联合益肾活血汤治疗腰椎间盘突出症的临床疗效。方法选取2019年9月至2020年5月收治的138例腰椎间盘突出症患者为研究对象,按照随机数字表法分为2组,对照组69例采用常规推拿治疗,治疗组69例予扶阳罐循经温推联合益肾活血汤治疗。2组均治疗10天后统计疗效,比较2组治疗前后疼痛症状[分别用日本骨科学会(JOA)下腰痛评分及疼痛视觉模拟评分法(VAS)评分进行评定]及炎症因子[包括白细胞介素6(IL-6)、肿瘤坏死因子α(TNF-α)及IL-4]水平变化情况,比较2组治疗期间不良反应发生状况。结果与本组治疗前比较,2组治疗后JOA下腰痛评分均升高(P<0.05),疼痛VAS评分均降低(P<0.05),且治疗组治疗后JOA下腰痛评分高于对照组(P<0.05),疼痛VAS评分低于对照组(P<0.05)。与本组治疗前比较,2组治疗后血清炎症因子IL-6、TNF-α水平均降低(P<0.05),IL-4水平均升高(P<0.05),且治疗组治疗后IL-6、TNF-α水平均低于对照组(P<0.05),IL-4水平高于对照组(P<0.05)。治疗组不良反应总发生率4.3%(3/69),对照组不良反应总发生率7.2%(5/69),2组不良反应总发生率比较差异无统计学意义(P>0.05)。结论扶阳罐循经温推联合益肾活血汤治疗腰椎间盘突出症疗效确切,可有效改善患者疼痛症状,抑制炎症反应,临床应用安全可靠。 展开更多
关键词 椎间盘突出 腰椎 推拿疗法 中药疗法
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基于MRI定量非对称回波最小二乘估算水脂分离技术的成人腰椎骨髓脂肪与年龄和性别的相关性研究
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作者 张伟 廖荣萍 +5 位作者 叶浩翊 陈兴奎 何金坤 席维佳 张宇桐 蔡金辉 《中国脊柱脊髓杂志》 CAS CSCD 北大核心 2024年第2期121-127,共7页
目的:基于MRI定量非对称回波最小二乘估算水脂分离(iterative decomposition of water and fat with echo asymmetry and least-squares estimation image quantitation,IDEAL-IQ)技术探讨成年人腰椎不同节段骨髓脂肪与年龄和性别的关... 目的:基于MRI定量非对称回波最小二乘估算水脂分离(iterative decomposition of water and fat with echo asymmetry and least-squares estimation image quantitation,IDEAL-IQ)技术探讨成年人腰椎不同节段骨髓脂肪与年龄和性别的关系。方法:收集298例受检者的MRI IDEAL-IQ脂肪分数图像,其中男性138例,女性160例,年龄20~69岁。将所有患者按照每10岁为一个年龄段分为5组:20~29岁(20~组),男24例,女20例;30~39岁(30~组),男47例,女39例;40~49岁(40~组),男36例,女47例;50~59岁(50~组),男20例,女37例;60~69岁(60~组),男11例,女17例。使用脂肪分数图在GE ADW4.6工作站测量L1~L5的骨髓质子密度脂肪分数(proton density fat fraction,PDFF)。结果:同一年龄组、不同性别间PDFF存在差异,20~、30~、40~组人群中,男性L1~L5椎体PDFF均高于女性(P<0.05);50~组人群中男性L1~L5椎体PDFF与女性的差异无统计学意义(P>0.05);60~组人群,男性L1~L5椎体PDFF均低于女性(P<0.05)。腰椎椎体PDFF与年龄呈正相关,女性(r=0.72,P<0.05)相关性高于男性(r=0.32,P<0.05)。从20~69岁,男性L4 PDFF增长率最大(21.08%),女性L1 PDFF增长率最大(65.68%);男性各椎体PDFF增长主要集中在30~及50~组,其中L1、L4、L5椎体PDFF在50~组增长率最大,L2、L3椎体PDFF在30~岁组增长率最大;女性各椎体PDFF在30~组呈轻微下降趋势,此后各椎体PDFF逐渐升高,增长主要集中在40~、50~、60~三个年龄组,其中50~组增长率最大。结论:成人不同年龄组男女性各椎体脂肪分布存在差异,椎体PDFF增长率也有所不同;腰椎不同节段椎体PDFF均与年龄呈正相关。 展开更多
关键词 磁共振成像 定量非对称回波最小二乘估算水脂分离技术 腰椎 骨髓 脂肪组织
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经皮椎间孔镜脊柱系统术对老年LDH合并神经根管狭窄患者腰椎功能及手术效果研究
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作者 唐礼明 陈义 桂德建 《临床和实验医学杂志》 2024年第4期392-396,共5页
目的 探讨经皮椎间孔镜脊柱系统(TESSYS)术对老年腰椎间盘突出症(LDH)并神经根管狭窄患者腰椎功能的影响并分析手术效果。方法 前瞻性纳入2020年6月至2023年6月安庆市立医院收治的老年LDH并神经根管狭窄患者66例,按随机抽签法分成TESSY... 目的 探讨经皮椎间孔镜脊柱系统(TESSYS)术对老年腰椎间盘突出症(LDH)并神经根管狭窄患者腰椎功能的影响并分析手术效果。方法 前瞻性纳入2020年6月至2023年6月安庆市立医院收治的老年LDH并神经根管狭窄患者66例,按随机抽签法分成TESSYS组与对照组,各33例。对照组行椎板开窗减压加髓核摘除术,TESSYS组行TESSYS术。记录并比较两组手术时间、术中出血量、术后卧床时间、住院时间,术前、术后3 d的血清肿瘤坏死因子-α(TNF-α)、皮质醇、促肾上腺皮质激素(ACTH)水平。比较术前、术后3个月的腰椎曲度、腰骶角角度,运动、感觉神经传导速度,并进行疼痛视觉模拟法(VAS)评分、Oswestry功能障碍指数(ODI)评分,记录并比较术后总体疗效与并发症情况。结果 TESSYS组的手术时间、术中出血量、术后卧床时间、住院时间分别为(76.35±8.21) min、(72.36±6.28) mL、(27.35±2.17) h、(6.31±1.42) d,均短(少)于对照组[(112.49±12.10) min、(133.67±15.69) mL、(30.91±1.06) h、(8.03±1.97) d],差异均有统计学意义(P<0.05)。术后3 d,两组血清TNF-α、皮质醇、ACTH水平较术前增高,且TESSYS组血清TNF-α、皮质醇、ACTH水平分别为(3.15±0.65) ng/mL、(2.69±0.41)μmol/L、(14.21±2.36) pmol/L,均低于对照组[(3.59±0.47) ng/mL、(3.06±0.87)μmol/L、(16.98±3.18) pmol/L],差异均有统计学意义(P<0.05)。术后3个月,两组的腰椎曲度均术前升高,腰骶角角度均较术前降低,且TESSYS组的腰椎曲度为(22.87±4.36) mm,高于对照组[(20.93±3.04) mm],腰骶角角度为(25.39±4.15)°,低于对照组[(27.91±2.90)°],差异均有统计学意义(P<0.05)。术后3个月,两组神经传导速度均较术前升高,且TESSYS组的神经传导速度均高于对照组,差异均有统计学意义(P<0.05)。术后3个月,两组的VAS、ODI评分均较术前降低,且TESSYS组的VAS、ODI评分分别为(2.14±0.51)、(17.50±2.11)分,均低于对照组[(3.10±0.92)、(20.39±3.63)分],差异均有统计学意义(P<0.05)。TESSYS组手术优良率为96.97%,高于对照组(75.76%),差异有统计学意义(P<0.05)。两组并发症发生率比较,差异无统计学意义(P>0.05)。结论 TESSYS术能进一步促进老年LDH并神经根管狭窄患者围术期机体功能恢复,减轻炎症与应激反应,改善神经传导速度与腰椎功能,缓解疼痛,提升手术效果。 展开更多
关键词 腰椎间盘突出症 神经根管狭窄 经皮椎间孔镜脊柱系统术 腰椎功能 疼痛
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改良悬吊复位法联合经皮椎体成形术治疗骨质疏松性胸腰椎压缩性骨折的临床研究 被引量:2
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作者 鲁玉州 王雨 +6 位作者 杨晓旭 吴成强 张守翠 王金国 吴亚东 秦东 丁林 《中国骨伤》 CAS CSCD 2024年第1期21-26,共6页
目的:探讨改良悬吊复位法联合经皮椎体成形术治疗骨质疏松性胸腰椎压缩骨折的临床疗效。方法:自2020年2月至2021年10月采用经皮椎体成形术治疗胸腰椎骨质疏松性压缩骨折患者92例,按照治疗方式不同分为观察组和对照组,观察组先行改良悬... 目的:探讨改良悬吊复位法联合经皮椎体成形术治疗骨质疏松性胸腰椎压缩骨折的临床疗效。方法:自2020年2月至2021年10月采用经皮椎体成形术治疗胸腰椎骨质疏松性压缩骨折患者92例,按照治疗方式不同分为观察组和对照组,观察组先行改良悬吊复位法给予伤椎复位,再行经皮椎体成形术治疗,对照组则单纯给予经皮椎体成形术治疗。观察组47例,男20例,女27例;年龄59~76(69.74±4.50)岁;骨折椎体节段T_(10)2例,T_(11)7例,T_(12)19例,L_(11)4例,L25例;对照组45例,男21例,女24例;年龄61~78(71.02±3.58)岁;骨折椎体节段:T_(10)3例,T_(11)8例,T_(12)17例,L_(11)2例,L_(2)5例。观察术中骨水泥渗漏情况,记录并比较两组手术前后疼痛视觉模拟评分(visual analogue scale,VAS)、腰椎Oswestry功能障碍指数(Oswestry disability index,ODI)、伤椎前缘高度、伤椎后凸Cobb角及骨水泥注入量等指标。结果:所有患者获得随访,时间6~10(8.45±1.73)个月。观察组2例出现骨水泥渗漏,对照组3例出现骨水泥渗漏。观察组术后伤椎前缘高度较术前均增加(P<0.05),伤椎后凸Cobb角较术前降低(P<0.05);对照组术后伤椎后凸Cobb角及伤椎前缘高度与术前比较,差异无统计学意义(P>0.05);观察组术后伤椎后凸Cobb角(9.82±2.55)°,低于对照组(15.87±4.60)°(P<0.05),伤椎前缘高度观察组(21.29±3.65)mm,高于对照组(17.16±2.91)mm(P<0.05)。观察组VAS术前(7.32±1.05)分,术后1周及3、6个月分别为(3.56±1.18)、(1.83±0.67)、(1.27±0.34)分,ODI评分术前(40.12±14.69)分,术后1周及3、6个月分别为(23.76±10.19)、(20.15±6.39)、(13.45±3.46)分。对照组VAS术前(7.11±5.26)分,术后1周及3、6个月分别为(3.82±0.68)、(1.94±0.88)、(1.36±0.52)分,ODI评分术前(41.38±10.23)分,术后1周及3、6个月分别为(25.13±14.22)、(20.61±5.82)、(14.55±5.27)分。两组术后VAS、ODI评分较术前均下降(P<0.05),术后两组VAS及ODI比较,差异无统计学意义(P>0.05)。结论:改良悬吊复位法联合PVP手术治疗骨质疏松性胸腰椎压缩骨折均取得良好的临床疗效,可有效减轻患者腰背部疼痛,恢复椎体高度,矫正后凸畸形,改善患者腰椎功能,提高患者生活质量。 展开更多
关键词 悬吊复位法 胸腰椎 骨质疏松性骨折 压缩性骨折
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韧带损伤影响腰椎稳定性的生物力学特征 被引量:2
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作者 李银倩 吕杰 +5 位作者 丁立军 王多多 郭潘靖 曹金凤 周楠 吕强 《中国组织工程研究》 CAS 北大核心 2024年第21期3286-3292,共7页
背景:韧带是维持腰椎稳定的重要结构,由于产生的机械应力这些结构容易退化,而对于韧带损伤的研究较少。目的:基于三维有限元模型模拟韧带损伤,确定各个韧带在运动状态下的活动度及应力方面的作用,系统探讨韧带受损对腰椎稳定性的影响和... 背景:韧带是维持腰椎稳定的重要结构,由于产生的机械应力这些结构容易退化,而对于韧带损伤的研究较少。目的:基于三维有限元模型模拟韧带损伤,确定各个韧带在运动状态下的活动度及应力方面的作用,系统探讨韧带受损对腰椎稳定性的影响和生物力学意义。方法:建立腰椎L4-L5有限元模型,约束L5下表面所有自由度,施加5 N·m力矩模拟腰椎的各个运动状态,通过改变韧带弹性模量模拟韧带渐进式受损。结果与结论:①大部分韧带损伤伸展活动度都出现了明显的增大;相比之下侧弯活动度无明显变化。②关节囊韧带受损后前屈、后伸和侧弯的活动度明显增大;前纵韧带受损后伸展活动度明显增大;横突韧带损伤导致侧弯活动度明显增大。③单韧带损伤后,伸展时活动度变化最为显著;单韧带受损后剩余韧带应力增大,尤其是关节囊韧带;整体来看棘间韧带和黄韧带应力变化最不明显;韧带应力在侧弯状态下变化最小,而扭转状态下变化最大。④韧带受损并未导致椎间盘压力发生重大变化,提示韧带损伤导致腰椎活动度增大,影响腰椎稳定性。⑤关节囊韧带稳定前屈、后伸和侧弯;前纵韧带稳定后伸;横突韧带稳定侧弯。⑥后伸运动对韧带损伤敏感,可通过后伸运动检查韧带病理变化。⑦单韧带损伤后剩余韧带给予应力补偿以维持腰椎稳定性。⑧棘间韧带和黄韧带损伤对周围韧带影响最小,关节囊韧带损伤对周围韧带影响最大。⑨韧带损伤对侧弯运动下的剩余韧带应力影响最小,而对扭转运动下的韧带应力影响最大,韧带损伤患者应避免扭转运动;韧带损伤不影响椎间盘压力。 展开更多
关键词 有限元 腰椎 韧带 渐进性损伤 生物力学
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