Splenic lymphangiomatosis is a very rare condition that,from 1990 to date,has been described only nine times.In the present report,we describe the first case of splenic lymphangiomatosis with rapid growth during lacta...Splenic lymphangiomatosis is a very rare condition that,from 1990 to date,has been described only nine times.In the present report,we describe the first case of splenic lymphangiomatosis with rapid growth during lactation in a 35-year-old woman.We also underline the difficultly in making an accurate preoperative diagnosis,despite more modern imaging techniques.Total splenectomy was considered to be the treatment needed,both to make a definitive diagnosis and to exclude the presence of malignancy.展开更多
Lymphangioma is an uncommon benign tumor that develops in the lymphatic system. Abdominal lymphangiomatosis is extremely rare in adult patients, and the clinical symptoms of this condition are complicated and atypical...Lymphangioma is an uncommon benign tumor that develops in the lymphatic system. Abdominal lymphangiomatosis is extremely rare in adult patients, and the clinical symptoms of this condition are complicated and atypical. We report a case of abdominal lymphangiomatosis in a 38-year-old female who presented with intestinal bleeding and protein-losing enteropathy, as well as lesions in the lung and bones. A computed tomography scan revealed multiple small cystic lesions without enhancement. Histological examination revealed microscopic cysts were submucosal, with walls composed of thin fibrous tissue, and D2-40 stained highlight the lining of the lymphatic channels by immunohistochemical method. We make a comparison with the cases re-ported before, and also discuss the diagnose of diffuse pulmonary lymphangiomatosis and Gorham's disease.展开更多
BACKGROUND Abdominal lymphangiomatosis is a rare benign condition accounting for less than 1%of all the cases of lymphangiomatosis.Management usually involves radical surgical excision;however,depending upon the exten...BACKGROUND Abdominal lymphangiomatosis is a rare benign condition accounting for less than 1%of all the cases of lymphangiomatosis.Management usually involves radical surgical excision;however,depending upon the extent of involvement,patient condition,and absence of complications,conservative management can be also considered.CASE SUMMARY We present the case of a 32-year-old male who presented with short onset abdominal pain and melena.Physical examination findings were within normal limits,except for left lower abdominal tenderness.Upper gastrointestinal endoscopy was within normal limits.Abdominal and pelvic ultrasound and computed tomography(CT)scan revealed numerous,variably-sized cystic lesions within the abdominal cavity,exclusively and extensively affecting the small bowel mesentery with sparing of the retroperitoneum.The diagnosis was confirmed by CT and cytological examination.Radical surgical excision was technically impossible in this patient because of the extensive involvement of the mesentery;therefore,the patient was managed conservatively.CONCLUSION Extensive and exclusive small bowel mesentery involvement in abdominal lymphangiomatosis is rare.Imaging modalities play an important role in establishing the diagnosis and conservative management can be considered when surgery is technically impossible.展开更多
Diffuse pulmonary lymphangiomatosis （DPL） is a rare disease that is characterized by diffuse proliferation of abnormal pulmonary lymphatic channels. DPL occurs mostly in children and young adults and often undergoes...Diffuse pulmonary lymphangiomatosis （DPL） is a rare disease that is characterized by diffuse proliferation of abnormal pulmonary lymphatic channels. DPL occurs mostly in children and young adults and often undergoes a progressive clinical course, eventually causing deterioration of the lung. Both the clinical diagnosis and treatment of DPL remain a challenge. Here, we report a case of DPL in a 53-year-old Chinese woman with comprehensive investigations including pulmonary function tests, computer tomography （CT）, bronchoscopy and histological examination of the lung biopsy, and review the literature.展开更多
The present case describes an adult femaleZoogoneticus tequila showing a congenital, marked shortening with left deviation of the upper and lower jaws, in association with microphthalmia of the left eye. The fish was ...The present case describes an adult femaleZoogoneticus tequila showing a congenital, marked shortening with left deviation of the upper and lower jaws, in association with microphthalmia of the left eye. The fish was normally fed and had a normal reproductive behaviour. After spontaneous death occurred at an advanced age, the fish was submitted for necropsy examination, which revealed the presence of an oval, 1 cm× 0.5 cm× 0.5 cm in size, cystic structure containing clear amber fluid, located in the coelomic cavity, in place of the spleen. Histopathological examination revealed multiple cystic spaces empty or filled with a slightly eosinophilic, homogenous, proteinaceous material, and lined by flattened, vimentin-positive endothelial-like cells. Residual parts of splenic tissue were also admixed with cystic spaces, suggesting a final diagnosis of cystic lymphangiomatosis of the spleen, which has not been previously described in fish. This is the first report of multiple, life-compatible, congenital physical deformities in association with splenic lymphangiomatosis inZoogoneticus tequila.展开更多
文摘Splenic lymphangiomatosis is a very rare condition that,from 1990 to date,has been described only nine times.In the present report,we describe the first case of splenic lymphangiomatosis with rapid growth during lactation in a 35-year-old woman.We also underline the difficultly in making an accurate preoperative diagnosis,despite more modern imaging techniques.Total splenectomy was considered to be the treatment needed,both to make a definitive diagnosis and to exclude the presence of malignancy.
文摘Lymphangioma is an uncommon benign tumor that develops in the lymphatic system. Abdominal lymphangiomatosis is extremely rare in adult patients, and the clinical symptoms of this condition are complicated and atypical. We report a case of abdominal lymphangiomatosis in a 38-year-old female who presented with intestinal bleeding and protein-losing enteropathy, as well as lesions in the lung and bones. A computed tomography scan revealed multiple small cystic lesions without enhancement. Histological examination revealed microscopic cysts were submucosal, with walls composed of thin fibrous tissue, and D2-40 stained highlight the lining of the lymphatic channels by immunohistochemical method. We make a comparison with the cases re-ported before, and also discuss the diagnose of diffuse pulmonary lymphangiomatosis and Gorham's disease.
文摘BACKGROUND Abdominal lymphangiomatosis is a rare benign condition accounting for less than 1%of all the cases of lymphangiomatosis.Management usually involves radical surgical excision;however,depending upon the extent of involvement,patient condition,and absence of complications,conservative management can be also considered.CASE SUMMARY We present the case of a 32-year-old male who presented with short onset abdominal pain and melena.Physical examination findings were within normal limits,except for left lower abdominal tenderness.Upper gastrointestinal endoscopy was within normal limits.Abdominal and pelvic ultrasound and computed tomography(CT)scan revealed numerous,variably-sized cystic lesions within the abdominal cavity,exclusively and extensively affecting the small bowel mesentery with sparing of the retroperitoneum.The diagnosis was confirmed by CT and cytological examination.Radical surgical excision was technically impossible in this patient because of the extensive involvement of the mesentery;therefore,the patient was managed conservatively.CONCLUSION Extensive and exclusive small bowel mesentery involvement in abdominal lymphangiomatosis is rare.Imaging modalities play an important role in establishing the diagnosis and conservative management can be considered when surgery is technically impossible.
文摘Diffuse pulmonary lymphangiomatosis （DPL） is a rare disease that is characterized by diffuse proliferation of abnormal pulmonary lymphatic channels. DPL occurs mostly in children and young adults and often undergoes a progressive clinical course, eventually causing deterioration of the lung. Both the clinical diagnosis and treatment of DPL remain a challenge. Here, we report a case of DPL in a 53-year-old Chinese woman with comprehensive investigations including pulmonary function tests, computer tomography （CT）, bronchoscopy and histological examination of the lung biopsy, and review the literature.
文摘The present case describes an adult femaleZoogoneticus tequila showing a congenital, marked shortening with left deviation of the upper and lower jaws, in association with microphthalmia of the left eye. The fish was normally fed and had a normal reproductive behaviour. After spontaneous death occurred at an advanced age, the fish was submitted for necropsy examination, which revealed the presence of an oval, 1 cm× 0.5 cm× 0.5 cm in size, cystic structure containing clear amber fluid, located in the coelomic cavity, in place of the spleen. Histopathological examination revealed multiple cystic spaces empty or filled with a slightly eosinophilic, homogenous, proteinaceous material, and lined by flattened, vimentin-positive endothelial-like cells. Residual parts of splenic tissue were also admixed with cystic spaces, suggesting a final diagnosis of cystic lymphangiomatosis of the spleen, which has not been previously described in fish. This is the first report of multiple, life-compatible, congenital physical deformities in association with splenic lymphangiomatosis inZoogoneticus tequila.
