Phospholipids are a major kind of lipids in rice grains and have fundamental nutritional andfunctional benefits to the plant. Their lyso forms （lysophospholipids, LPLs） often form inclusion complexeswith amylose or ...Phospholipids are a major kind of lipids in rice grains and have fundamental nutritional andfunctional benefits to the plant. Their lyso forms （lysophospholipids, LPLs） often form inclusion complexeswith amylose or independently influence the physicochemical and functional properties of rice starch.However, the genetic basis for LPL synthesis in rice endosperm is largely unknown. Here, we performeda preliminary association test of 13 LPL compositions among 20 rice accessions, and identified 22putative main-effect quantitative trait loci responsible for all LPLs except for LPC14：0 and LPE14：0. Fivederived cleaved amplified polymorphic sequences and one insertion/deletion marker for threeLPL-synthesis-related candidate genes were developed. Association analysis revealed two markerssignificantly associated with starch LPL traits. These results provide an insight into the genetic basis ofphospholipid biosynthesis in rice and may contribute to the rice quality breeding programs usingfunctional markers.展开更多
Nerve regeneration in the central nervous system（CNS）has become a holy grail of biomedical research.To understand nerve growth that would be required for efficient regeneration,many scientists have turned to develop...Nerve regeneration in the central nervous system（CNS）has become a holy grail of biomedical research.To understand nerve growth that would be required for efficient regeneration,many scientists have turned to developing systems where nerve growth is abundant and normal neural connections are established.One aspect of this neural development,which would also be important in nerve regeneration,展开更多
This study was conducted to evaluate the influence of dietary lysophospholipids combined with 1%dietary fish oil reduction on the growth performance and hepatic lipid metabolism of largemouth bass(Micropterus salmoide...This study was conducted to evaluate the influence of dietary lysophospholipids combined with 1%dietary fish oil reduction on the growth performance and hepatic lipid metabolism of largemouth bass(Micropterus salmoides).Five isonitrogenous feeds were prepared with lysophospholipids at 0%(fish oil group,FO),0.05%(L-0.05),0.1%(L-0.1),0.15%(L-0.15)and 0.2%(L-0.2),respectively.The dietary lipid was 11%in the FO diet and 10%in the other diets.Largemouth bass were fed for 68 d(initial body weight=6.04±0.01 g)with 4 replicates per group and 30 fish per replicate.The results showed that the fish fed diet containing 0.1%lysophospholipids had higher digestive enzyme activity and obtained better growth performance compared to the fish fed FO diet(P<0.05).The feed conversion rate in the L-0.1 group was significantly lower than that in the other groups.Serum total protein and triglyceride contents in L-0.1 group were significantly higher than those in other groups(P<0.05)and the contents of total cholesterol and low-density lipoprotein cholesterol in L-0.1 group were significantly lower than those in FO group(P<0.05).The activity and genes expression of hepatic glucolipid metabolizing enzymes in L-0.15 group were significantly increased compared to those in FO group(P<0.05).Reducing 1%fish oil along with 0.1%lysophospholipids added to the feed could improve the digestion and absorption of nutrients,enhance the activity of liver glycolipid metabolizing enzymes,and thus effectively promote the growth of largemouth bass.展开更多
基金financially supported by the Fundamental Research Funds for the Central Universities at Zhejiang University,Hangzhou,China(Grant No.2016XZZX001-09)
文摘Phospholipids are a major kind of lipids in rice grains and have fundamental nutritional andfunctional benefits to the plant. Their lyso forms （lysophospholipids, LPLs） often form inclusion complexeswith amylose or independently influence the physicochemical and functional properties of rice starch.However, the genetic basis for LPL synthesis in rice endosperm is largely unknown. Here, we performeda preliminary association test of 13 LPL compositions among 20 rice accessions, and identified 22putative main-effect quantitative trait loci responsible for all LPLs except for LPC14：0 and LPE14：0. Fivederived cleaved amplified polymorphic sequences and one insertion/deletion marker for threeLPL-synthesis-related candidate genes were developed. Association analysis revealed two markerssignificantly associated with starch LPL traits. These results provide an insight into the genetic basis ofphospholipid biosynthesis in rice and may contribute to the rice quality breeding programs usingfunctional markers.
基金supported by the National Eye Institute of the National Institutes of Health under Award Number R15EY024453
文摘Nerve regeneration in the central nervous system（CNS）has become a holy grail of biomedical research.To understand nerve growth that would be required for efficient regeneration,many scientists have turned to developing systems where nerve growth is abundant and normal neural connections are established.One aspect of this neural development,which would also be important in nerve regeneration,
基金supported by Guangdong Provincial Special Fund for Modern Agriculture Industry Technology Innovation Team(2023KJ150)Special Project on Key Fields of Guangdong Universities(Rural Revitalization)(2020ZDZX1034).
文摘This study was conducted to evaluate the influence of dietary lysophospholipids combined with 1%dietary fish oil reduction on the growth performance and hepatic lipid metabolism of largemouth bass(Micropterus salmoides).Five isonitrogenous feeds were prepared with lysophospholipids at 0%(fish oil group,FO),0.05%(L-0.05),0.1%(L-0.1),0.15%(L-0.15)and 0.2%(L-0.2),respectively.The dietary lipid was 11%in the FO diet and 10%in the other diets.Largemouth bass were fed for 68 d(initial body weight=6.04±0.01 g)with 4 replicates per group and 30 fish per replicate.The results showed that the fish fed diet containing 0.1%lysophospholipids had higher digestive enzyme activity and obtained better growth performance compared to the fish fed FO diet(P<0.05).The feed conversion rate in the L-0.1 group was significantly lower than that in the other groups.Serum total protein and triglyceride contents in L-0.1 group were significantly higher than those in other groups(P<0.05)and the contents of total cholesterol and low-density lipoprotein cholesterol in L-0.1 group were significantly lower than those in FO group(P<0.05).The activity and genes expression of hepatic glucolipid metabolizing enzymes in L-0.15 group were significantly increased compared to those in FO group(P<0.05).Reducing 1%fish oil along with 0.1%lysophospholipids added to the feed could improve the digestion and absorption of nutrients,enhance the activity of liver glycolipid metabolizing enzymes,and thus effectively promote the growth of largemouth bass.
