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Study on the Urbanization-based Restructuring of Urban Spaces in Meizhou City of China 被引量:3
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作者 刘德良 李坤新 邱国锋 《Journal of Landscape Research》 2012年第3期35-40,共6页
By introducing the urbanization history of Meizhou City,major problems of its spatial structure were summarized as small scale of urban areas and incomplete hierarchical structure;poor cohesive force of central city,i... By introducing the urbanization history of Meizhou City,major problems of its spatial structure were summarized as small scale of urban areas and incomplete hierarchical structure;poor cohesive force of central city,imbalanced regional spatial ratio;disorderly development of urban spaces;and fierce competition for space.Then spatial restructuring of Meizhou City was discussed from the following 3 perspectives:optimizing hierarchical structure of space,planning in advance to construct a central city with more than 1 million residents;establishing the traffic hub of Guangdong,Fujian and Jiangxi;improving spatial structure of industries.It was to enhance sustainable social and economic development of the local area,break the dualistic structure and realize the overall development of urban and rural areas,and also narrow the urban-rural gap. 展开更多
关键词 URBANIZATION SPATIAL restructuring meizhou CITY
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Financial Strategy during Power System Restructuring
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作者 吴志勇 《Electricity》 2001年第2期9-10,共2页
Aiming at the problems of power structure irrationality, lagging of power network behind power source development and high proportion of overdone and small sized units existing currently in power system in China, fina... Aiming at the problems of power structure irrationality, lagging of power network behind power source development and high proportion of overdone and small sized units existing currently in power system in China, financial and running strategies are set forth corresponding to power system restructuring. 展开更多
关键词 financial strategy power system restructuring
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The causes and environmental effects of land use conversion during agricultural restructuring in Northeast China 被引量:6
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作者 刘彦随 甘红 +1 位作者 Jay GAO DENG Xusheng 《Journal of Geographical Sciences》 SCIE CSCD 2004年第4期488-494,共7页
During the last decade of the 20th century, extensive conversion inagricultural land use took place in Northeast China. The goal of this study is to ascertain itsspatial distribution and regional differentiation, dete... During the last decade of the 20th century, extensive conversion inagricultural land use took place in Northeast China. The goal of this study is to ascertain itsspatial distribution and regional differentiation, determine its causes, and analyze itsenvironmental impact. Especially we attempt to elucidate how institutional constraints havefacilitated the change at a time of agrarian restructuring when newly emerging free market washybridized with the former planned economy. Information on six categories of land use was mappedfrom interpretation of Landsat TM images recorded in 1990, 1995 and 2000. Most of land use changestook place during the first half of the decade, coinciding with abrupt and chaotic changes ingovernment directives. Farmland was changed mainly to woodland, water body and built-up areas whilewoodland and grassland were converted chiefly to farmland. Spatially, the change from farmland towoodland was restricted to the west of the study area. The change from grassland to farmland tookplace in the grazing and farming interlocked west. These chaotic and occasionally conflictingchanges were largely caused by lack of stability and consistency in agricultural land use policiespromulgated. They have exerted adverse impacts on the local environment, including land degradation,increased flooding, and modified climate regime. 展开更多
关键词 land use conversion agricultural restructuring remote sensing environmental effects northeast China
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Grain boundary restructuring and La/Ce/Y application in Nd–Fe–B magnets 被引量:4
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作者 Mi Yan Jiaying Jin Tianyu Ma 《Chinese Physics B》 SCIE EI CAS CSCD 2019年第7期25-53,共29页
Since the 1980 s, Nd–Fe–B with largest energy product(BH)max approaching the theoretical limit has become the landmark of permanent magnetic material.The application spectrum for Nd–Fe–B continues to expand over t... Since the 1980 s, Nd–Fe–B with largest energy product(BH)max approaching the theoretical limit has become the landmark of permanent magnetic material.The application spectrum for Nd–Fe–B continues to expand over time both in the industrial and commercial sectors, which leads to growing research interests for solving the long-standing drawbacks of Nd–Fe–B, i.e., poor corrosion resistance, low coercivity, high Dy/Tb and low La/Ce/Y consumption.Concerning the above obstacles, we aim to present the novel grain boundary restructuring(GBR) approach, from GB design, processing, to structure evolution and property evaluation with a focus on the corrosion and coercivity mechanism of the restructured 2:14:1-typed magnets.Starting with an introduction to the fundamental of GBR, two representative examples,high-electrode-potential(Pr, Nd)32.5Fe62.0Cu5.5 and low-melting-point Dy71.5Fe28.5, are given with detailed descriptions of the advantages of GBR to enhance the intrinsic anti-corrosion stability and to strengthen the coercivity at low Dy consumption.Microstructure–property correlations are established to understand the critical importance of regulating the restructured GB phase to maximize the all-round performance of the 2:14:1-typed permanent magnets.Aiming at sustainable and balanced development of rare earth(RE) industry, the proceeding section proposes new prototypes of La–Ce and Y–Ce co-substitutions with dual benefits of stabilizing the 2:14:1 tetragonal phase and strengthening the intrinsic hard magnetism.The findings of additional REFe2 intergranular phase delight that the GBR approach also opens up a new horizon of research and application to develop high-performance La/Ce/Y-rich permanent magnets with deliberately tailored GB phase. 展开更多
关键词 GRAIN boundary restructuring COERCIVITY corrosion resistance Dy/Tb La/Ce/Y
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Hollow Villages and Rural Restructuring in Major Rural Regions of China: A Case Study of Yucheng City, Shandong Province 被引量:29
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作者 SUN Hu LIU Yansui XU Keshuai 《Chinese Geographical Science》 SCIE CSCD 2011年第3期354-363,共10页
The agricultural land resources of China are relatively limited because of its large population.Therefore,balancing the land use for industrialization,urbanization,and food security is a big challenge.In recent years,... The agricultural land resources of China are relatively limited because of its large population.Therefore,balancing the land use for industrialization,urbanization,and food security is a big challenge.In recent years,rural hollowing in China has resulted in numerous of abandoned rural houses,and the areas with abandoned houses need to be restored into agricultural land with effective land consolidation techniques.This study used the method of benefit-cost analysis and the data collected through field surveys conducted in Yucheng City in the northwest of Shandong Province in March 2009,to examine how hollow villages (HVs) to be created and how to solve the problem.The qualitative and quantitative analyses indicate following results.1) The situation of HVs is becoming increasingly severe under rapid industrialization and urbanization in Yucheng City.2) Poor infrastructure in rural areas and incomplete urbanization are the main factors that have led to the rural hollowing in many major rural regions of China.3) In order to resolve the problem caused by HVs and increase agricultural land,reconstructing rural communities in the countryside is necessary.4) A new mechanism in the provision of compensation funds by developed regions to the villages in less-developed regions must be established. 展开更多
关键词 hollow villages (HVs) village regrouping rural restructuring Yucheng City
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Diagenesis and Restructuring Mechanism of Oil and Gas Reservoir in the Marine Carbonate Formation,Northeastern Sichuan:A Case Study of the Puguang Gas Reservoir 被引量:2
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作者 DU Chunguo WANG Jianjun +2 位作者 ZOU Huayao ZHU Yangming WANG Cunwu 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2009年第6期1173-1181,共9页
Based on the technology of balanced cross-section and physical simulation experiments associated with natural gas geochemical characteristic analyses, core and thin section observations, it has been proven that the Pu... Based on the technology of balanced cross-section and physical simulation experiments associated with natural gas geochemical characteristic analyses, core and thin section observations, it has been proven that the Puguang gas reservoir has experienced two periods of diagenesis and restructuring since the Late Indo-Chinese epoch. One is the fluid transfer controlled by the tectonic movement and the other is geochemical reconstruction controlled by thermochemical sulfate reduction (TSR). The middle Yanshan epoch was the main period that the Puguang gas reservoir experienced the geochemical reaction of TSR. TSR can recreate the fluid in the gas reservoir, which makes the gas drying index higher and carbon isotope heavier because C2+ (ethane and heavy hydrocarbon) and 12C (carbon 12 isotope) is first consumed relative to CH4 and 13C (carbon 13 isotope). However, the reciprocity between fluid regarding TSR (hydrocarbon, sulfureted hydrogen (H2S), and water) and reservoir rock results in reservoir rock erosion and anhydrite alteration, which increases porosity in reservoir, thereby improving the petrophysical properties. Superimposed by later tectonic movement, the fluid in Puguang reservoir has twice experienced adjustment, one in the late Yanshan epoch to the early Himalayan epoch and the other time in late Himalayan epoch, after which Puguang gas reservoir is finally developed. 展开更多
关键词 diagenesis and restructuring mechanism marine carbonate formation thermochemical sulfate reduction Puguang gas reservoir
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Electrochemical Surface Restructuring of Phosphorus-Doped Carbon@MoP Electrocatalysts for Hydrogen Evolution 被引量:5
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作者 Huimin Jiang Liting Yan +6 位作者 Shuo Zhang Yanchao Zhao Xue Yang Yameng Wang Jianxing Shen Xuebo Zhao Lianzhou Wang 《Nano-Micro Letters》 SCIE EI CAS CSCD 2021年第12期484-498,共15页
The hydrogen evolution reaction(HER) through electrocatalysis is promising for the production of clean hydrogen fuel. However,designing the structure of catalysts,controlling their electronic properties,and manipulati... The hydrogen evolution reaction(HER) through electrocatalysis is promising for the production of clean hydrogen fuel. However,designing the structure of catalysts,controlling their electronic properties,and manipulating their catalytic sites are a significant challenge in this field. Here,we propose an electrochemical surface restructuring strategy to design synergistically interactive phosphorus-doped carbon@MoP electrocatalysts for the HER. A simple electrochemical cycling method is developed to tune the thickness of the carbon layers that cover on MoP core,which significantly influences HER performance. Experimental investigations and theoretical calculations indicate that the inactive surface carbon layers can be removed through electrochemical cycling,leading to a close bond between the MoP and a few layers of coated graphene. The electronsdonated by the MoP core enhance the adhesion and electronegativity of the carbon layers;the negatively charged carbon layers act as an active surface. The electrochemically induced optimization of the surface/interface electronic structures in the electrocatalysts significantly promotes the HER. Using this strategy endows the catalyst with excellent activity in terms of the HER in both acidic and alkaline environments(current density of 10 mA cm^(-2) at low overpotentials,of 68 mV in 0.5 M H_(2)SO_(4) and 67 mV in 1.0 M KOH). 展开更多
关键词 Electrochemical surface restructuring Hydrogen evolution molybdenum phosphide nanowires Phosphorus-doped carbon Synergistic interaction
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Optimal restructuring strategies under various dynamic factors 被引量:1
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作者 MENG Qing-xuan 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 SCIE EI CAS CSCD 2007年第6期932-938,共7页
Corporate restructuring was identified as a new industrial force that has great impact on economic values and that therefore has become central in daily financial decision making. This article investigates the optimal... Corporate restructuring was identified as a new industrial force that has great impact on economic values and that therefore has become central in daily financial decision making. This article investigates the optimal restructuring strategies under different dynamic factors and their numerous impacts on firm value. The concept of quasi-leverage is introduced and valuation models are built for corporate debt and equity under imperfect market conditions. The model’s input variables include the quasi-leverage and other firm-specific parameters, the output variables include multiple corporate security values. The restruc- turing cost is formulated in the form of exponential function, which allows us to observe the sensitivity of the variation in security values. The unified model and its analytical solution developed in this research allow us to examine the continuous changes of security values by dynamically changing the coupon rates, riskless interest rate, bankruptcy cost, quasi-leverage, personal tax rate, corporate taxes rate, transaction cost, firm risk, etc., so that the solutions provide useful guidance for financing and restructuring decisions. 展开更多
关键词 restructuring Capital structure Financial decisions
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Post-industrial Economic Restructuring and Wage Inequality in Urban China, 2003-2015: A Sectoral Perspective 被引量:1
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作者 YANG Fiona Fan HU Fox Zhiyong WANG Yuhua 《Chinese Geographical Science》 SCIE CSCD 2020年第3期516-531,共16页
Income inequality in urban China has attracted growing attention from China’s urban researchers and policy makers. Whereas many studies have interrogated the pattern and process of the income gap in Chinese cities un... Income inequality in urban China has attracted growing attention from China’s urban researchers and policy makers. Whereas many studies have interrogated the pattern and process of the income gap in Chinese cities undergoing the institutional transformation from plan to market, relatively little is known about how such unequal distribution of income is related to China’s ongoing structural transformation toward a post-industrial economy. Drawing on a decomposition methodology based on the Theil index, this study aimed to address this lacuna through an empirical investigation of China’s urban wage inequality from a sectoral perspective. Our empirical study identified the low-wage manufacturing sector and the high-wage producer services sector as the two biggest contributors to urban wage inequality in China. Urban wage inequality within the producer services was found to be caused by the spatial concentration of a disproportionate number of high-paying jobs in a few developed, high-tier city-regions on the eastern coast. Our empirical findings have important implications for the formulation of policies to address the income inequality that plagues China’s continuing urbanization. 展开更多
关键词 wage inequality post-industrial economy economic restructuring producer service urban China
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STRUCTURE AND RESTRUCTURING OF BEIJING-TIANJIN-HEBEI MEGALOPOLIS IN CHINA 被引量:1
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作者 YU Tao-fang 《Chinese Geographical Science》 SCIE CSCD 2006年第1期1-8,共8页
Scott proposes to use the term global city-regions to designate the phenomena that bear some resemblance to the "world cities" firstly identified by Hall and Friedmann and Wolff, and to the "global citi... Scott proposes to use the term global city-regions to designate the phenomena that bear some resemblance to the "world cities" firstly identified by Hall and Friedmann and Wolff, and to the "global cities" of Sassen but whose essential social logic and contextual characteristics have evolved considerably since these pioneering studies were published. In simple geographical terms, a global city-region can be refered to comprise any major metropolitan area or any contiguous set of metropolitan areas together with a surrounding hinterland of variable extent-itself a locus of scattered urban settlements-whose internal economic and political affairs are bound up in intricate ways in intensifying and far-flung extra-national relationships. Scott refers to these extra-national relationships as a symptom of "globalization". As economic motors and political actors, the global city regions have been regarded as crucial parts of development strategies in China. In the "Eleventh Five-year Plan" issued by the National Development and Reform Commission of P. R. China, the Beijing-Tianjin-Hebei Province (Jing-Jin-Ji) region, one of the typical megalopolises or global city regions in the East Coastal China is paid more attention. This paper first analyzes the regional structure of the Jing-Jin-Ji region based on data of the fifth national population census of China. And then through the changes of the population growth, the dynamic process and mechanisms of the regional restructuring in the Jing-Jin-Ji is explored and discussed. 展开更多
关键词 regional structure regional restructuring Beijing-Tianjin-Hebei (Jing-Jin-Ji)
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Decentralization,spatial disequilibrium,and restructuring of coastal tourist destination-Empirical research from Sanya,China 被引量:1
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作者 Hu Yu Tian Chen +2 位作者 Kaiyong Wang Xiyue Zhang Fubiao Zhu 《Chinese Journal of Population,Resources and Environment》 2014年第1期68-79,共12页
The objective of this article is to speculate on resort restructuring in the market-oriented reform process in China.Previous studies show that spatial disequilibrium was aggravated by decentralization,which leads to ... The objective of this article is to speculate on resort restructuring in the market-oriented reform process in China.Previous studies show that spatial disequilibrium was aggravated by decentralization,which leads to the difference in tourism policy and investment,public goods,and service;a profound analytical framework is much needed for further empirical studies.This article has reviewed the relevant studies on links between decentralization and restructuring,spatial influences of decentralization on tourism,based on which we put forward the theoretical framework of resort spatial restructuring from the view of political economy analysis,then we elaborate on and discuss it based on the example of Sanya,China.In short,the article suggests that decentralization of fiscal responsibilities and institutional power contributes to the spatial disequilibrium of tourism industrial structure,land use,public infrastructure and service facilities,and to community inequality.Interests of government,investors,and community should be comprehensively coordinated in the resort spatial restructuring process from three aspects:restructuring government,optimizing space structure,and tourism industry.Furthermore,we argue that resort restructuring in the context of Sanya requires coordination of various interest groups through four ways:restructure the government power under administrative division adjustment,optimizing spatial structure,expanding industrial space to diversified tourism products,and building resort management services organization.Finally,we discussed some policy requirements for resort sustainable development. 展开更多
关键词 coastal resort spatial disequilibrium DECENTRALIZATION spatial restructuring Sanya
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Dynamic surface restructuring of nanoporous Cu_(2-x)Se for efficient CO_(2) electroreduction into methanol 被引量:1
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作者 Xin Lin Xunlin Liu +5 位作者 Yang Zhao Jiao Lan Kang Jiang Zhixiao Liu Feng Xie Yongwen Tan 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2022年第8期514-520,I0014,共8页
The nanoporous Cu_(2-x)Se with Cu(Se-5%)surface catalysts were prepared through in situ dynamic restructuring strategy during the electrochemical process,which achieves highly selective electrochemical CO_(2) reductio... The nanoporous Cu_(2-x)Se with Cu(Se-5%)surface catalysts were prepared through in situ dynamic restructuring strategy during the electrochemical process,which achieves highly selective electrochemical CO_(2) reduction to methanol.In situ and quasi-operando spectroscopic results provide a deep insight into the catalytic active centres of reconstructed heterogeneous catalysts for CO_(2) electroreduction. 展开更多
关键词 Surface restructuring NANOPOROUS Cu_(2-x)Se Carbon dioxide reduction mETHANOL
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Restructuring and Sustainability-Corporate Strategy of Commercial Bank in Thailand: A Siam Commercial Bank 被引量:1
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作者 Boriboon Pinprayong Winai Wongsurawat 《Chinese Business Review》 2012年第8期719-729,共11页
This article presents a case study of the Siam Commercial Bank (SCB) by investigating why and how SCB implemented organizational restructuring during the uncertain economic environment, and gives an overview of the ... This article presents a case study of the Siam Commercial Bank (SCB) by investigating why and how SCB implemented organizational restructuring during the uncertain economic environment, and gives an overview of the Thai commercial bank industry. This article presents and discusses SCB's strategy implementation in its organization during 1997-2010. This case study is aimed to provide some guidelines for other companies in developing and in choosing strategies for their business sustainability in the global change, and in choosing the implementation of their organization structure for competitive markets. 展开更多
关键词 business sustainability organizational restructuring corporate strategy BANKING Thailand
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TEMPORAL AND SPATIAL DIFFERENCES OF THE INDUSTRIAL RESTRUCTURING OF GUANGDONG PROVINCE IN THE 1990S
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作者 阎小培 贾莉 +1 位作者 林锡艺 黄谦 《Chinese Geographical Science》 SCIE CSCD 1999年第4期35-42,共8页
This paper focuses on the temporal and spatial change of industrial structure in Guangdong Province since the 1990s. The attention is initially paid to the change of industrial structure through analyzing the structur... This paper focuses on the temporal and spatial change of industrial structure in Guangdong Province since the 1990s. The attention is initially paid to the change of industrial structure through analyzing the structure change of the three sectors, and the change of internal structures of agriculture, industry and tertiary sector respectively. Then the spatial differences of industrial restructuring are analyzed based on the four economic regions which have been agreed in the academic field: the Zhujiang(Pearl) River Delta, northern mountain region, east and west wings. Thirdly, the reasons for the spatial differences of industrial restructuring are examined. Finally a short conclusion is drawn and some suggestions for the regional integration are put forward. 展开更多
关键词 industrial restructuring TEmPORAL and SPATIAL DIFFERENCES GUANGDONG PROVINCE
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罗汉果苷V调控高糖状态巨噬细胞M1极化促进骨髓间充质干细胞的成骨分化
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作者 叶枝茂 惠久莹 +2 位作者 钟晓霞 麦昱颖 李昊 《中国组织工程研究》 CAS 北大核心 2025年第19期3968-3975,共8页
背景:糖尿病微环境会造成巨噬细胞过度M1极化,这种高糖炎症状态会抑制骨髓间充质干细胞的成骨分化,从而影响糖尿病骨缺损的愈合。研究表明罗汉果苷Ⅴ具有抗炎、抗氧化、降血糖的作用,但其能否调节高糖炎症状态下巨噬细胞M1极化及骨髓间... 背景:糖尿病微环境会造成巨噬细胞过度M1极化,这种高糖炎症状态会抑制骨髓间充质干细胞的成骨分化,从而影响糖尿病骨缺损的愈合。研究表明罗汉果苷Ⅴ具有抗炎、抗氧化、降血糖的作用,但其能否调节高糖炎症状态下巨噬细胞M1极化及骨髓间充质干细胞的成骨分化尚不清楚。目的:探讨罗汉果苷Ⅴ在高糖炎症状态下调节巨噬细胞M1型极化对骨髓间充质干细胞成骨分化的影响。方法:构建糖尿病C57BL/6小鼠模型,从正常和糖尿病小鼠分离骨髓来源巨噬细胞,分别培养于低糖和高糖培养基。使用脂多糖和干扰素γ作为炎症刺激诱导骨髓来源巨噬细胞的M1型极化,同时以160,320,640μmol/L罗汉果苷Ⅴ干预,用流式细胞术检测F4/80^(+)CD86^(+)细胞比例,qRT-PCR检测诱导型一氧化氮合酶、白细胞介素1β、白细胞介素6的mRNA表达水平,ELISA检测骨髓来源巨噬细胞上清液中肿瘤坏死因子α水平。分离C57BL/6小鼠骨髓间充质干细胞,分别使用低糖或高糖成骨诱导液诱导成骨分化,添加M1型巨噬细胞条件培养基作为炎症刺激,以及320μmol/L罗汉果苷Ⅴ干预,成骨诱导14 d后采用qRT-PCR检测碱性磷酸酶、Runt相关因子2、骨钙素、骨桥蛋白的mRNA表达水平,成骨诱导21 d后进行茜素红染色及定量分析。结果与结论:①流式细胞术结果显示320,640μmol/L罗汉果苷Ⅴ组的F4/80^(+)CD86^(+)细胞比例明显低于高糖炎症对照组(P<0.05);②qRT-PCR结果显示160,320,640μmol/L罗汉果苷Ⅴ组的诱导型一氧化氮合酶、白细胞介素6的mRNA相对表达量较高糖炎症对照组显著降低(P<0.05),320,640μmol/L罗汉果苷Ⅴ组白细胞介素1β的mRNA相对表达量较高糖炎症对照组显著降低(P<0.05);③ELISA结果显示160,320,640μmol/L罗汉果苷Ⅴ组的肿瘤坏死因子α分泌水平较高糖炎症对照组显著降低(P<0.05);④320μmol/L罗汉果苷Ⅴ干预后,高糖炎症状态下骨髓间充质干细胞的钙盐沉积增加(P<0.05),且碱性磷酸酶、Runt相关因子2和骨桥蛋白的mRNA相对表达量增加(P<0.05)。结果表明,罗汉果苷Ⅴ可通过抑制高糖炎症状态下骨髓来源巨噬细胞的M1型极化及炎症因子表达,促进骨髓间充质干细胞的成骨分化。 展开更多
关键词 罗汉果苷Ⅴ 巨噬细胞 m1型极化 骨髓间充质干细胞 炎症反应 成骨分化 高糖
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M2型巨噬细胞衍生外泌体促进小胶质细胞M2型极化
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作者 方俊 魏伟 +5 位作者 薛亚婷 崔臣龙 卫嘉晟 石筱 杨丽娟 杨保仲 《中国组织工程研究》 CAS 北大核心 2025年第25期5320-5327,共8页
背景:目前对于M2型巨噬细胞衍生外泌体的研究多集中于促进伤口愈合及成骨细胞的增殖和分化,而很少有研究关注其对小胶质细胞表型的调控作用。目的:探讨M2型巨噬细胞衍生外泌体对于小胶质细胞的表型调控作用及分子机制。方法:①提取骨髓... 背景:目前对于M2型巨噬细胞衍生外泌体的研究多集中于促进伤口愈合及成骨细胞的增殖和分化,而很少有研究关注其对小胶质细胞表型的调控作用。目的:探讨M2型巨噬细胞衍生外泌体对于小胶质细胞的表型调控作用及分子机制。方法:①提取骨髓原代巨噬细胞,用50 ng/m L白细胞介素4刺激巨噬细胞24 h促进巨噬细胞M2型极化,流式细胞术和细胞免疫荧光鉴定M2型巨噬细胞标志物CD206;②提取和鉴定M2型巨噬细胞衍生外泌体;③将小胶质细胞BV2随机分为3组:对照组、脂多糖组、治疗组,对照组不做处理,脂多糖组加入500 ng/m L脂多糖干预24 h,治疗组同时加入500 ng/m L脂多糖和25μg/m L M2型巨噬细胞衍生外泌体干预24 h,ELISA检测培养上清中肿瘤坏死因子α和白细胞介素10的分泌量,q RT-PCR检测细胞中诱导型一氧化氮合酶、精氨酸酶1、白细胞介素1β和白细胞介素10的m RNA表达,Western blot检测诱导型一氧化氮合酶、精氨酸酶1的蛋白表达以及核因子κB信号通路相关蛋白表达。结果与结论:①ELISA结果显示,与对照组相比,脂多糖组肿瘤坏死因子α分泌明显增多;与脂多糖组相比,治疗组肿瘤坏死因子α的分泌减少而白细胞介素10的分泌增多;②q RT-PCR结果显示,与对照组相比,脂多糖组白细胞介素1β、诱导型一氧化氮合酶m RNA表达升高;与脂多糖组相比,治疗组白细胞介素1β、诱导型一氧化氮合酶m RNA表达降低,白细胞介素10、精氨酸酶1 m RNA表达升高;③Western blot结果显示,与对照组相比,脂多糖组诱导型一氧化氮合酶蛋白表达升高;与脂多糖组相比,治疗组诱导型一氧化氮合酶蛋白表达降低,而精氨酸酶1蛋白表达升高;(4)与对照组相比,脂多糖组核因子κB信号通路中P65、p-IκB-α蛋白表达降低;与脂多糖组相比,治疗组P65、p-IκB-α蛋白表达升高。结果表明:M2型巨噬细胞衍生外泌体可以显著抑制脂多糖诱导小胶质细胞的炎症反应,促进抗炎因子白细胞介素10的表达,抑制促炎因子肿瘤坏死因子α、白细胞介素1β的表达,促进小胶质细胞表型由M1型向M2型极化,其机制可能与M2型巨噬细胞衍生外泌体抑制核因子κB信号通路激活有关。 展开更多
关键词 m2巨噬细胞 外泌体 小胶质细胞 炎症 NF-ΚB信号通路 神经病理性疼痛 极化
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New Restructuring Model for Chinese M&S SOEs:A Case of Executive Holding Major Capital Stock
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作者 方润生 李垣 《Journal of Donghua University(English Edition)》 EI CAS 2002年第4期146-149,共4页
The reform for Chinese state-owned enterprises (SOEs)during the past twenty years selected several ways which couldn't solve essential problems and improve the performance of the SOEs in China. The reason is that ... The reform for Chinese state-owned enterprises (SOEs)during the past twenty years selected several ways which couldn't solve essential problems and improve the performance of the SOEs in China. The reason is that traditional ownership instituton wasn't changed at all,the institution reach an impasse in market system which resulted in the fact that SOEs couldn't get used to keen competition. This paper analyses an ownership restructuring case in which an executive holds major capital stock in a state textile institute restructured and therefore the state ownership was withdrawn from it completely, it expounds the rationality of the model selected and points out that the model is currently a very effective way by which M & S SOEs would withdraw from competitive business field successfully. 展开更多
关键词 SOEs: OWNERSHIP restructuring limited company controlling SHAREHOLDER
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Addressing the Negative Self-Concept in Posttraumatic Stress Disorder by a Three-Session Programme of Cognitive Restructuring and Imagery Modification (CRIM-PTSD): A Case Study
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作者 Meike Müller-Engelmann Kerstin Hadouch Regina Steil 《Journal of Behavioral and Brain Science》 2018年第5期319-327,共9页
Background: Cognitive restructuring and imagery modification for posttraumatic stress disorder (CRIM-PTSD) is a new intervention that involves only three sessions and focuses on the self-concept. It combines cognitive... Background: Cognitive restructuring and imagery modification for posttraumatic stress disorder (CRIM-PTSD) is a new intervention that involves only three sessions and focuses on the self-concept. It combines cognitive restructuring of core trauma-related dysfunctional beliefs and mental imagery. The effectiveness of CRIM-PTSD has recently been demonstrated in a pilot study. Method: This article presents a step-by-step description of the administration of CRIM-PTSD in a female survivor of childhood sexual abuse (CSA) suffering from PTSD and major depressive disorder related to strong self-blame. Results: The intervention showed substantial reductions in PTSD symptoms and depression in the patient comparable to those observed in the pilot study. Conclusions: CRIM-PTSD might provide an economical tool for reducing PTSD symptoms when only a short time is available for intervention. Furthermore, this tool could be included in well-established PTSD treatments. In addition to the pilot study, a randomized controlled trial is needed to further explore the feasibility and effectiveness of this short intervention. 展开更多
关键词 POSTTRAUmATIC Stress Disorder Cognitive restructuring Imagery SELF-CONCEPT
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Evaluation of the Environmental, Social Effects for the Egyptian National Railways Restructuring
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作者 Mahmoud Ahmed Mousa Ali Mohamed Abdelnaby El Sayed 《Journal of Transportation Technologies》 2015年第1期24-36,共13页
This paper presents the main findings of the environmental and social impact assessment (ESIA) for the Egyptian national railways restructuring. This paper consists of the two parts: 1) modernizing the signaling syste... This paper presents the main findings of the environmental and social impact assessment (ESIA) for the Egyptian national railways restructuring. This paper consists of the two parts: 1) modernizing the signaling system on the Arab El Raml-Alexandria Line and creating a Central Traffic Management Center in Tanta;and 2) renewing 200 km of track in Lower and Upper Egypt. The purpose of this evaluation is to identify and examine the potential socio-cultural, economic, and physical impacts of the railway restructuring, and propose measures to mitigate its adverse impacts, and develop plans for managing and monitoring the environmental aspects of the railway restructuring. This paper describes outlines of the environmental and social sensitivities of the railway restructuring area, potentially significant impacts of the proposed project and plans for their mitigation. Detailed information on the environmental and socio economic settings of the railway restructuring, components and activities of the proposed project and the results of the environmental and social impact assessment studies are presented in the body of the paper. 展开更多
关键词 RAILWAY RAILWAY restructuring Environmental Quality Socio ECONOmIC Volume of POPULATIONS
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Research on Impact of Urban System Hierarchy Restructuring upon Spatial Planning
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作者 LI Alin 《Journal of Landscape Research》 2015年第4期53-57,共5页
Economy is a major force in determining the hierarchy of urban system. As regional economy globalizes, urban systems in many countries are making their transition from the scale-based hierarchy to the networked system... Economy is a major force in determining the hierarchy of urban system. As regional economy globalizes, urban systems in many countries are making their transition from the scale-based hierarchy to the networked system, while that in China still maintains an administrative stratification. The paper discussed the triumph of Baigou Town in the East Baoding Sub-center Campaign. It significantly shattered the administrative hierarchy of the urban system in China, which owes largely to the new type of economical development, i.e. government-led fixed assets investment and real estate development, as demonstrated in the urban expansion. Under the pattern of "territory" logic, spatial planning not only lost efficacy, but also stimulated bottom-up over development in local areas. The paper recommended foreign action- and collaboration-oriented urban planning theories, and that the absolute top-down spatial blueprint planning must be abandoned, and a harmonious synergy of planning roles, work content and methodology be facilitated. 展开更多
关键词 Urban system Hierarchy restructuring Spatial planning "Territory" logic
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