目的:引进改良婴幼儿孤独症量表(Modified Checklist for Autism in Toddlers,M-CHAT),并检验信效度。方法:对93名符合美国精神障碍诊断与统计手册第4版(DSM-Ⅳ)诊断标准的门诊就诊的儿童孤独症患儿进行M-CHAT中文版评定,其中64名患儿...目的:引进改良婴幼儿孤独症量表(Modified Checklist for Autism in Toddlers,M-CHAT),并检验信效度。方法:对93名符合美国精神障碍诊断与统计手册第4版(DSM-Ⅳ)诊断标准的门诊就诊的儿童孤独症患儿进行M-CHAT中文版评定,其中64名患儿同时评定儿童孤独症行为量表(ABC),56名患儿同时评定儿童孤独症评定量表(CARS),以检验其校标效度。53名患儿2～4周后再次进行M-CHAT中文版评定,以检验重测信度。对85名正常儿童进行M-CHAT中文版评定。共有117名被试(56名孤独症儿童,61名正常对照)的2位家长同时单独对被试进行M-CHAT中文版评定,以检验评分者信度。结果:M-CHAT中文版单项评分者信度Kappa值为0.24～1,总分评分者信度相关系数为0.79;单项重测信度Kappa值为0.27～1,总分重测信度相关系数为0.77(均P<0.01)。M-CHAT中文版内部一致性检验Cronbachα系数为0.85(P<0.01)。M-CHAT中文版各条目与总分之间的相关系数为-0.21～0.73;M-CHAT中文版总分与ABC、CARS总分之间的相关系数分别为0.34与0.53(均P<0.01)。M-CHAT中文版的灵敏度为0.96,特异度为0.60。结论:改良婴幼儿孤独症量表中文版的总体信度、效度较好,灵敏度较高,可用于我国儿童孤独症的早期筛查;但其特异度偏低,有待进一步修订完善。展开更多
The increasing prevalence of Autism Spectrum Disorder makes it as considerable issue worldwide.Recent studies addresses the hot topic of Mirror Neuronal System(MNS)confers behind the ASD.However,the cause is uncertain...The increasing prevalence of Autism Spectrum Disorder makes it as considerable issue worldwide.Recent studies addresses the hot topic of Mirror Neuronal System(MNS)confers behind the ASD.However,the cause is uncertain,Indian population prone to varied prenatal and postnatal factors of the condition.Indian parents and professional still be at the initial awareness phase of the spectrum.Years of delay in identification and intervention while comparing with world standards due to various Indian socio-economic and socio-cultural factors.Less availability of screening and diagnostic tools headed to relay on culturally irrelevant and expensive international tools.Government funded research initiatives developed ISAA,INDT-ASD,CASI and AIIMS Modified INDT-ASD as culturally relevant indigenous tools and available on practice.So far,the tools have their own advantages and limitations,requires further research and progression.Owing to scarcity of trained professionals for a wide population range,home based parent-mediated therapies be the most preferred mode of therapy.However,the therapeutic options vary with people.The study aimed to ascertain the present Indian scenario,look upon the awareness about the condition,availability of screening and diagnostic facilities,the early identification and timely intervention program.In addition,the study briefly confers the biological and clinical background of ASD.展开更多
Item Response Theory (IRT) models have been extensively used in the field of education to identify link between a response to a test item and underlying latent capability of the test taker. We demonstrate the benefit ...Item Response Theory (IRT) models have been extensively used in the field of education to identify link between a response to a test item and underlying latent capability of the test taker. We demonstrate the benefit of using IRT model to analyze health data using data from M. chat program such that statisticians can use the method in lieu of traditional methods including Cronbach’s alpha, discriminant analysis and factor analysis. M. chat is a technology based health coaching program and the baseline survey from the participants in the program includes response in different but correlated domains of diet, social habits, leisure practices, mental health, substance abuse, self-sufficiency and medication adherence. We analyzed baseline data from 416 subjects using IRT models. Our results indicated that responses pertaining to alcohol and substance abuse were the most discriminating items with an average discrimination estimate of approximately 4.99 whereas the least discriminating items were the diet habits, with an average estimate of -0.476.展开更多
文摘目的:引进改良婴幼儿孤独症量表(Modified Checklist for Autism in Toddlers,M-CHAT),并检验信效度。方法:对93名符合美国精神障碍诊断与统计手册第4版(DSM-Ⅳ)诊断标准的门诊就诊的儿童孤独症患儿进行M-CHAT中文版评定,其中64名患儿同时评定儿童孤独症行为量表(ABC),56名患儿同时评定儿童孤独症评定量表(CARS),以检验其校标效度。53名患儿2～4周后再次进行M-CHAT中文版评定,以检验重测信度。对85名正常儿童进行M-CHAT中文版评定。共有117名被试(56名孤独症儿童,61名正常对照)的2位家长同时单独对被试进行M-CHAT中文版评定,以检验评分者信度。结果:M-CHAT中文版单项评分者信度Kappa值为0.24～1,总分评分者信度相关系数为0.79;单项重测信度Kappa值为0.27～1,总分重测信度相关系数为0.77(均P<0.01)。M-CHAT中文版内部一致性检验Cronbachα系数为0.85(P<0.01)。M-CHAT中文版各条目与总分之间的相关系数为-0.21～0.73;M-CHAT中文版总分与ABC、CARS总分之间的相关系数分别为0.34与0.53(均P<0.01)。M-CHAT中文版的灵敏度为0.96,特异度为0.60。结论:改良婴幼儿孤独症量表中文版的总体信度、效度较好,灵敏度较高,可用于我国儿童孤独症的早期筛查;但其特异度偏低,有待进一步修订完善。
文摘The increasing prevalence of Autism Spectrum Disorder makes it as considerable issue worldwide.Recent studies addresses the hot topic of Mirror Neuronal System(MNS)confers behind the ASD.However,the cause is uncertain,Indian population prone to varied prenatal and postnatal factors of the condition.Indian parents and professional still be at the initial awareness phase of the spectrum.Years of delay in identification and intervention while comparing with world standards due to various Indian socio-economic and socio-cultural factors.Less availability of screening and diagnostic tools headed to relay on culturally irrelevant and expensive international tools.Government funded research initiatives developed ISAA,INDT-ASD,CASI and AIIMS Modified INDT-ASD as culturally relevant indigenous tools and available on practice.So far,the tools have their own advantages and limitations,requires further research and progression.Owing to scarcity of trained professionals for a wide population range,home based parent-mediated therapies be the most preferred mode of therapy.However,the therapeutic options vary with people.The study aimed to ascertain the present Indian scenario,look upon the awareness about the condition,availability of screening and diagnostic facilities,the early identification and timely intervention program.In addition,the study briefly confers the biological and clinical background of ASD.
文摘Item Response Theory (IRT) models have been extensively used in the field of education to identify link between a response to a test item and underlying latent capability of the test taker. We demonstrate the benefit of using IRT model to analyze health data using data from M. chat program such that statisticians can use the method in lieu of traditional methods including Cronbach’s alpha, discriminant analysis and factor analysis. M. chat is a technology based health coaching program and the baseline survey from the participants in the program includes response in different but correlated domains of diet, social habits, leisure practices, mental health, substance abuse, self-sufficiency and medication adherence. We analyzed baseline data from 416 subjects using IRT models. Our results indicated that responses pertaining to alcohol and substance abuse were the most discriminating items with an average discrimination estimate of approximately 4.99 whereas the least discriminating items were the diet habits, with an average estimate of -0.476.
