Modelling based on multi-agent system (MAS) was built for the current production management and process of Shenyang Songyang Paper Cup Co., Ltd. It can transmit the information instantly via order agent (OA), manager ...Modelling based on multi-agent system (MAS) was built for the current production management and process of Shenyang Songyang Paper Cup Co., Ltd. It can transmit the information instantly via order agent (OA), manager agent (MA), production agent (PA), and service agent (SA), and realize information sharing. The PA is also built on MAS, and it includes two agents, task agent (TA), and resource agent (RA). It has been found that the modelling is superior to the old one. It can improve the working flow and production efficiency, and shorten the time of delivery.展开更多
A rigid rods model for real-time simulation of cloth is presented, which can be used in e-commerce applications, games or Virtual Reality environment. The proposed algorithm simplifies the basic mass-spring model by r...A rigid rods model for real-time simulation of cloth is presented, which can be used in e-commerce applications, games or Virtual Reality environment. The proposed algorithm simplifies the basic mass-spring model by replacing the springs connection of masses with the rigid rods, and using the Verlet Integration method to calculate the position and velocity of the masses. Compared the efficiency and the effect of simulation with other similar systems, this algorithm is faster and realistic for some real-time applications.展开更多
We previously found that the K141N mutation in heat shock protein B8(HSPB8) was responsible for Charcot-Marie-Tooth disease type 2L in a large Chinese family.The objective of the present study was to generate a transg...We previously found that the K141N mutation in heat shock protein B8(HSPB8) was responsible for Charcot-Marie-Tooth disease type 2L in a large Chinese family.The objective of the present study was to generate a transgenic mouse model bearing the K141N mutation in the human HSPB8 gene,and to determine whether this K141NHSPB8 transgenic mouse model would manifest the clinical phenotype of Charcot-Marie-Tooth disease type 2L,and consequently be suitable for use in studies of disease pathogenesis.Transgenic mice overexpressing K141NHSPB8 were generated using K141N mutant HSPB8 cDNA cloned into a pCAGGS plasmid driven by a human cytomegalovirus expression system.PCR and western blot analysis confirmed integration of the K141NHSPB8 gene and widespread expression in tissues of the transgenic mice.The K141NHSPB8 transgenic mice exhibited decreased muscle strength in the hind limbs and impaired motor coordination,but no obvious sensory disturbance at 6 months of age by behavioral assessment.Electrophysiological analysis showed that the compound motor action potential amplitude in the sciatic nerve was significantly decreased,but motor nerve conduction velocity remained normal at 6 months of age.Pathological analysis of the sciatic nerve showed reduced myelinated fiber density,notable axonal edema and vacuolar degeneration in K141NHSPB8 transgenic mice,suggesting axonal involvement in the peripheral nerve damage in these animals.These findings indicate that the K141NHSPB8 transgenic mouse successfully models Charcot-Marie-Tooth disease type 2L and can be used to study the pathogenesis of the disease.展开更多
通过仿真实验进行演示、检验和评估,是研究信息化战场火力与指挥控制的有效方法。通过采用基于M A S的仿真方法,把火力战系统的内部组元直接映射成相应的A gen t,研究了基于M A S的火力战仿真建模过程,提出了基于M A S建模的火力战系统...通过仿真实验进行演示、检验和评估,是研究信息化战场火力与指挥控制的有效方法。通过采用基于M A S的仿真方法,把火力战系统的内部组元直接映射成相应的A gen t,研究了基于M A S的火力战仿真建模过程,提出了基于M A S建模的火力战系统总体框架与工作过程,并进一步研究了火力战A gen t的定义与工作原理,为未来信息化战场火力战相关项目技术演示提供平台基础。展开更多
文摘Modelling based on multi-agent system (MAS) was built for the current production management and process of Shenyang Songyang Paper Cup Co., Ltd. It can transmit the information instantly via order agent (OA), manager agent (MA), production agent (PA), and service agent (SA), and realize information sharing. The PA is also built on MAS, and it includes two agents, task agent (TA), and resource agent (RA). It has been found that the modelling is superior to the old one. It can improve the working flow and production efficiency, and shorten the time of delivery.
基金Science Research Foundation of Beijing Municipal Education Commission(No.KM200310012049)
文摘A rigid rods model for real-time simulation of cloth is presented, which can be used in e-commerce applications, games or Virtual Reality environment. The proposed algorithm simplifies the basic mass-spring model by replacing the springs connection of masses with the rigid rods, and using the Verlet Integration method to calculate the position and velocity of the masses. Compared the efficiency and the effect of simulation with other similar systems, this algorithm is faster and realistic for some real-time applications.
基金funded by the National Natural Science Foundation of China,No.81071001,30900805
文摘We previously found that the K141N mutation in heat shock protein B8(HSPB8) was responsible for Charcot-Marie-Tooth disease type 2L in a large Chinese family.The objective of the present study was to generate a transgenic mouse model bearing the K141N mutation in the human HSPB8 gene,and to determine whether this K141NHSPB8 transgenic mouse model would manifest the clinical phenotype of Charcot-Marie-Tooth disease type 2L,and consequently be suitable for use in studies of disease pathogenesis.Transgenic mice overexpressing K141NHSPB8 were generated using K141N mutant HSPB8 cDNA cloned into a pCAGGS plasmid driven by a human cytomegalovirus expression system.PCR and western blot analysis confirmed integration of the K141NHSPB8 gene and widespread expression in tissues of the transgenic mice.The K141NHSPB8 transgenic mice exhibited decreased muscle strength in the hind limbs and impaired motor coordination,but no obvious sensory disturbance at 6 months of age by behavioral assessment.Electrophysiological analysis showed that the compound motor action potential amplitude in the sciatic nerve was significantly decreased,but motor nerve conduction velocity remained normal at 6 months of age.Pathological analysis of the sciatic nerve showed reduced myelinated fiber density,notable axonal edema and vacuolar degeneration in K141NHSPB8 transgenic mice,suggesting axonal involvement in the peripheral nerve damage in these animals.These findings indicate that the K141NHSPB8 transgenic mouse successfully models Charcot-Marie-Tooth disease type 2L and can be used to study the pathogenesis of the disease.
文摘通过仿真实验进行演示、检验和评估,是研究信息化战场火力与指挥控制的有效方法。通过采用基于M A S的仿真方法,把火力战系统的内部组元直接映射成相应的A gen t,研究了基于M A S的火力战仿真建模过程,提出了基于M A S建模的火力战系统总体框架与工作过程,并进一步研究了火力战A gen t的定义与工作原理,为未来信息化战场火力战相关项目技术演示提供平台基础。