Assessment of Retention Ponds and Its Impacts on Health of Residents in Mogadishu, Somalia: Mixed Methods

The purpose of this study was to evaluate the effects of retention ponds on the environment and population health by analyzing water samples from various ponds in Mogadishu, to determine the prevalence of waterborne illnesses that occur during the rainy season in Mogadishu, and to find out what experts thought about the effects of retention ponds on the environment as well as population health in Mogadishu. Methods: Mixed designs were used in the study. The first design is an exploratory study where samples are taken from different retention ponds in Mogadishu. The second design involves gathering secondary data from the online FSNAU Dashboard regarding the incidence of rainfall and waterborne illnesses including malaria and cholera. Additionally, a cross-sectional survey of expert opinions using questionnaires was the third design. The 10 water samples were taken from retention ponds in Mogadishu as part of the sample size. Data on the fourth month was also gathered using the FNSAU dashboard, and seventy sample sizes were used for the expert self-administered questionnaire for the third design. Excel was used for data analysis in the initial design. While BMI SPSS versions 22 were used to analyze the data from the Self-administered Questionnaire, additional methods were utilized to compute descriptive statistics, such as mean and standard deviation, and to analyze demographic data in a frequency table. Findings: The results show that three samples had unsatisfactory scores (Grade D): Yaqshid (Warshadda Bastada) had a WQI of 80.85, Boondheer (Bondher Pond) had a WQI of 80.64, and Wartanabad (Xamar Jadiid Pond) had a WQI of 80.89. The remaining samples were all rated as fair (grade), which indicates that they ranged from 50 to 75. The months with the largest rainfall already occurred in December, November, and October, when the prevalence of diseases during the rainy season was highest for cholera cases. Although October and December saw a significant number of malaria cases, November did not. Retention ponds’ overall effects on residential environments were evaluated, and the results showed that the standard deviation was 0.802 and the cumulative average mean scores were 4.41 overall. This indicates that the respondents were in agreement that retention ponds in Mogadishu, Somalia, had an effect on residential areas. Recommendation: The study suggested that in order to identify retention pond contamination and create treatment units for its management, the Ministry of Health forms a district-level public health committee. All districts must have a sewer system installed by the local government, and retention ponds must be made easier in order to move waste outside of the city.

Factors Promoting Retention of Nurses in Three Private Hospitals of Lahore: A Cross Sectional Descriptive Survey

Introduction: Pakistan has a large number of professional nurses but a higher rate of turnover contributes towards the shortage of nurses which is intensified by nurses’ immigration, lack of recruitment of new nurses and retirement of senior nurses. Aim: The study aimed at examining the factors that increase retention of nurses. Research Method: The study is descriptive cross sectional with a sample of 150 nurses including both the genders, from 3 private hospitals located in Pakistan. A convenient sampling technique was used. The data collection was done through close ended questionnaires based on 20 questions. Data collection was done quantitatively and then data was entered in SPSS. Correlation and regression tests were performed. Findings: The analysis revealed that 91.3% nurses are loyal to their hospitals but, 8.7%nurses can switch the hospital for different reasons. It was also found that the idea of leaving the job based on the intention of moving to abroad and public sector was higher than the retirement and other causes. Resultantly, enhancements in nurses’ work environments have the ability to decrease nurses’ job burnout and turnover and increase patients’ satisfaction. Recommendations: Hospital leaders should implement effective strategies to encourage nurses to continue their job by motivation, strengthening management skills within the hospital and improving a positive work environment by promoting teamwork, continuous learning, trust, respect and flexible arrangements which can lead towards achieving better results.However, further studies quantitatively and qualitatively can explore more factors related to dissatisfaction of nurses. Health systems policy makers should lead by developing related strategies for the retention of nurses.

Bio-Based Waterborne Poly(Vanillin-Butyl Acrylate)/MXene Coatings for Leather with Desired Warmth Retention and Antibacterial Properties

This study presents a solvent-free,facile synthesis of a bio-based green antibacterial agent and aromatic monomer methacrylated vanillin(MV)using vanillin.The resulting MV not only imparted antibacterial properties to coatings layered on leather,but could also be employed as a green alternative to petroleum-based carcinogen styrene(St).Herein,MV was copolymerized with butyl acrylate(BA)to obtain waterborne bio-based P(MV-BA)miniemulsion via miniemulsion polymerization.Subsequently,MXene nanosheets with excellent photothermal conversion performance and antibacterial properties,were introduced into the P(MV-BA)miniemulsion by ultrasonic dispersion.During the gradual solidification of P(MV-BA)/MXene nanocomposite miniemulsion on the leather surface,MXene gradually migrated to the surface of leather coatings due to the cavitation effect of ultrasonication and amphiphilicity of MXene,which prompted its full exposure to light and bacteria,exerting the maximum photothermal conversion efficiency and significant antibacterial efficacy.In particular,when the dosage of MXene nanosheets was 1.4 wt%,the surface temperature of P(MV-BA)/MXene nanocomposite miniemulsioncoated leather(PML)increased by about 15℃ in an outdoor environment during winter,and the antibacterial rate against Escherichia coli and Staphylococcus aureus was nearly 100%under the simulated sunlight treatment for 30 min.Moreover,the introduction of MXene nanosheets increased the air permeability,water vapor permeability,and thermal stability of these coatings.This study provides a new insight into the preparation of novel,green,and waterborne bio-based nanocomposite coatings for leather,with desired warmth retention and antibacterial properties.It can not only realize zerocarbon heating based on sunlight in winter,reducing the use of fossil fuels and greenhouse gas emissions,but also improve ability to fight off invasion by harmful bacteria,viruses,and other microorganisms.

Establishment of predictive models and determinants of preoperative gastric retention in endoscopic retrograde cholangiopancreatography

BACKGROUND Study on influencing factors of gastric retention before endoscopic retrograde cholangiopancreatography(ERCP)background:With the wide application of ERCP,the risk of preoperative gastric retention affects the smooth progress of the operation.The study found that female,biliary and pancreatic malignant tumor,digestive tract obstruction and other factors are closely related to gastric retention,so the establishment of predictive model is very important to reduce the risk of operation.METHODS A retrospective analysis was conducted on 190 patients admitted to our hospital for ERCP preparation between January 2020 and February 2024.Patient baseline clinical data were collected using an electronic medical record system.Patients were randomly matched in a 1:4 ratio with data from 190 patients during the same period to establish a validation group(n=38)and a modeling group(n=152).Patients in the modeling group were divided into the gastric retention group(n=52)and non-gastric retention group(n=100)based on whether gastric retention occurred preoperatively.General data of patients in the validation group and identify factors influencing preoperative gastric retention in ERCP patients.A predictive model for preoperative gastric retention in ERCP patients was constructed,and calibration curves were used for validation.The receiver operating characteristic(ROC)curve was analyzed to evaluate the predictive value of the model.RESULTS We found no statistically significant difference in general data between the validation group and modeling group(P>0.05).The comparison of age,body mass index,hypertension,and diabetes between the two groups showed no statistically significant difference(P>0.05).However,we noted statistically significant differences in gender,primary disease,jaundice,opioid use,and gastrointestinal obstruction between the two groups(P<0.05).Mul-tivariate logistic regression analysis showed that gender,primary disease,jaundice,opioid use,and gastrointestinal obstruction were independent factors influencing preoperative gastric retention in ERCP patients(P<0.05).The results of logistic regression analysis revealed that gender,primary disease,jaundice,opioid use,and gastroin-testinal obstruction were included in the predictive model for preoperative gastric retention in ERCP patients.The calibration curves in the training set and validation set showed a slope close to 1,indicating good consistency between the predicted risk and actual risk.The ROC analysis results showed that the area under the curve(AUC)of the predictive model for preoperative gastric retention in ERCP patients in the training set was 0.901 with a standard error of 0.023(95%CI:0.8264-0.9567),and the optimal cutoff value was 0.71,with a sensitivity of 87.5 and specificity of 84.2.In the validation set,the AUC of the predictive model was 0.842 with a standard error of 0.013(95%CI:0.8061-0.9216),and the optimal cutoff value was 0.56,with a sensitivity of 56.2 and specificity of 100.0.CONCLUSION Gender,primary disease,jaundice,opioid use,and gastrointestinal obstruction are factors influencing preoperative gastric retention in ERCP patients.A predictive model established based on these factors has high predictive value.

A systematic review of the efficacy of traditional Chinese medicine retention enema in the treatment of ulcerative colitis

The objective of this study is to summarize the efficacy and safety of traditional Chinese medicine(TCM)enema in the treatment of ulcerative colitis(UC).The randomized controlled trials on TCM enema intervention in the treatment of UC were searched in seven databases:PubMed,Embase,Web of Science,CBM,CNKI,Wanfang Database,and VIP Database from January 1,2013 to June 6,2022,and the data were analyzed using RevMan 5.3 software.A total of 18 studies involving 1514 UC patients were included.Meta analysis results showed that compared with conventional Western medicine,Chinese medicine enema had a significant effect on UC,and the clinical effective rate of the experimental group using Chinese medicine enema was 4.45 times that of the control group using conventional Western medicine(odds ratio=4.45,95%confidence interval[3.27,6.06]).Therefore,Chinese medicine enema is effective in the treatment of UC,and can significantly reduce related symptoms.

High Urine Retention: Experience in a Series of Patients with Renal Failure Patients

Purpose: High urinary retention (HUR) can negatively impact renal function. Our study aimed to present the epidemiological, diagnostic, and therapeutic aspects of HUR in a Senegalese academic hospital. Patients and Methods: We conducted a retrospective study of 70 patients with HUR associated with renal failure from January 2017 to December 2020. Parameters examined included: age, sex, coexisting conditions affecting renal function, clinical symptoms, diagnostic tests, causes of HUR, urinary diversion, and patient outcomes. Results: The average age was 66, with a majority of male patients (87%). Twenty-three patients had pre-existing medical conditions. Oligo-anuria was the most common reason for detecting HUR (70%). Half of the patients had an ECOG score ≥ 2. The mean creatinine level was 50.7 mg/l. Nineteen patients exhibited hydroelectrolytic disorders. Bacterial colonization was observed in 25 patients. Ultrasound and computed tomography were the most frequently performed imaging tests (100% and 62.8%, respectively). Sixty-seven patients had ureterohydronephrosis (UHN), with bilateral UHN in 88.6% of cases. Pelvic cancers (47.1%) were the primary cause of HUR, primarily bladder cancers (27.1%). Nephrostomy was the most common urinary drainage method (50%), particularly for obstructions due to pelvic cancer (88.6%). The majority of patients (52.8%) regained normal renal function after drainage. Nineteen deaths occurred among elderly patients with compromised general health. Conclusion: Urinary drainage significantly improved renal function for most patients. Pelvic cancer emerged as the leading cause of HUR. Nephrostomy was the predominant drainage method.

Study on the Application Effect of Flexible Nursing Care in Patients with Postpartum Urinary Retention and its Effect on Lactation

Objective: To study the application effect of flexible nursing in patients with postpartum urinary retention and its effect on lactation. Methods: A total of 200 cases of postpartum urinary retention patients admitted between January 2021 and January 2022 were selected and randomly grouped into two groups, a control group (conventional nursing) and an observation group (flexible nursing), of 100 cases each. The time of onset of lactation, the lactation volume score, urinary indicators, the amount of post-partum hemorrhage, and the quality of life score of the two groups were compared. Results: The observation group’s lactation initiation time (21.41 ± 1.52) h and lactation volume score (2.11 ± 0.52) were better than that of the control group (P < 0.05). The observation group’s first urination time (2.11 ± 0.51) min was lower than the control group, while the urinary retention completely relieved time (33.12 ± 8.61) h, and first urinary volume (262.17 ± 52.41) mL was higher than that of the control group (P < 0.05). The amount of postpartum hemorrhage in the observation group (151.21 ± 22.12) mL was less than that in the control group (P < 0.05). The scores of somatic functioning (86.25 ± 2.20), psychological functioning (91.56 ± 1.45), social functioning (89.25 ± 2.45), and material life (89.75 ± 1.45) of the observation group were higher than those of the control group after nursing (P < 0.05). Conclusion: Flexible nursing care in patients with postpartum urinary retention exhibited significant nursing effects and lactation function was effectively improved.

Petroleum Retention,Intraformational Migration and Segmented Accumulation within the Organic-rich Shale in the Cretaceous Qingshankou Formation of the Gulong Sag,Songliao Basin,Northeast China

In this study,organic geochemical and petrological analyses were conducted on 111 shale samples from a well to understand the retention,intraformational migration and segmented accumulation(shale oil enrichment in different intervals is unconnected)features of shale oil within the organic-rich shale in the Qingshankou Formation of the Gulong Sag.Our study shows that retained petroleum characteristics in the investigated succession are mainly influenced by three factors:organic richness,intraformational migration and segmented accumulation.Organic matter richness primarily controls the amount of retained petroleum,especially the‘live’component indicated by the S_(2)value rather than the total organic carbon(TOC)figure alone.The negative expulsion efficiencies determined by mass-balance calculations of hydrocarbons reveal that petroleum from adjacent organic-rich intervals migrates into the interval of about 2386-2408 m,which is characterized by high free hydrocarbon(S_(1)),OSI and saturated hydrocarbons content,along with a greater difference inδ^(13)C values between polar compounds(including resins and asphaltenes)and saturated hydrocarbons.The depth-dependent heterogeneity of carbon isotope ratios(δ^(13)C)of mud methane gas,δ^(13)C of extracts gross composition(SARA),δ^(13)C of kerogen and SARA content of extracts suggest that the studied succession can be subdivided into four intervals.The shale oil sealing enrichment character in each interval is further corroborated by the distinctδ^(13)C values of mud methane gas in different intervals.Due to the migration of petroleum into the 2386-2408 m interval,the S_(1),OSI and saturated hydrocarbons content of the interval show higher relative values.The maturity of organic matter in the 2471-2500 m interval is at the highest with the smaller size molecular components of the retained petroleum.Thus,favorable‘sweet spots’may be found in the 2386-2408 m interval and the 2471-2500 m interval,according to the experiment results in this study.

How can we increase attraction and retention of nurses? A research with young nurses

The persistent challenges in attracting and retaining a diverse healthcare workforce, with a specific focus on nurses, have become increasingly pronounced in recent years. These hurdles have been exacerbated by a growing difficulty in retaining young nurses, thereby exacerbating labor shortages driven by demographic shifts and the retirement of experienced nursing professionals. While most research efforts have concentrated on the broader issue of nurse retention, our study is centered on a specific demographic—young nurses. Our research endeavors to shed light on the unique challenges faced by young nurses through a qualitative survey involving nursing students who are simultaneously employed. We seek to discern the multifaceted obstacles they encounter in both their academic environment and the healthcare organizations where they work. While certain challenges are linked to course organization, examinations, and the time required for studying, our respondents overwhelmingly emphasize the pivotal role of the work environment in facilitating the harmonization of work, family, and educational commitments. This reconciliation is achieved through measures such as flexible working arrangements and the efficient organization of nursing duties. The primary objective of our research is to provide insights into how these diverse challenges can be effectively addressed and how a range of measures can significantly contribute to the attraction and retention of nursing students, as well as the long-term retention of nurses within the healthcare system. Our recommendations are intended to be of practical use to a wide array of stakeholders, including academic institutions, particularly colleges and universities offering nursing programs, as well as hospitals, clinics, and other healthcare institutions that hire nurses. By collaboratively addressing these challenges and implementing the recommended measures, we aim to fortify the healthcare workforce and ensure the continued provision of quality care to patients. .

The Influence of Fabric Structural Parameters on Dust Retention Using a Simple, Newly Constructed Device

This article has been directed to Environment Protection Technology with the purpose of providing a new instrument designed and developed to measure filtration efficiency through the relationship between clean cloth fabric structural parameters, dust parameters, and test measuring variables. Fabric samples used throughout the present study were woven cotton 100%, polyester 100% and cotton/polyester 50/50%. The warp count: 30/2 for all fabric samples, the weft count is 9/1;12/1;and 20/1. The weave of satin, basket, and twill is 3/1 with four different picks/cm to produce the fabrics with the same cover factor. For dust separation fabrics range in weight from “300 - 450 g/m2” with an air permeability of “100 - 300 l/d m2·min” at “196.2 Pa” (20 mm WG) as specified in DIN 53887. Air permeability through fabrics depends entirely on the sieving percent of the surface of the fabric, which is partly the pores and partly the permeability through the yarns, which are the basic elements of a fabric. The results showed that dust capturing depends entirely on air permeability, which is related to fabric weave structure and fabric material at specified testing and measuring variables.

Intron Retention Fine-Tunes the Resistance of the Rice Mutant pls4 to Rice Sheath Blight(Rhizotonia solani AG I.1a)

OsPLS4 encodes aβ-ketoacyl carrier protein reductase(KAR).The role of OsPLS4 in rice sheath blight(Rhizoctonia solani)remains unclear.Our preliminary studies showed that premature leaf senescence mutants(pls4)were highly susceptive to sheath blight in the early stage of rice development.To explore the role of this gene in the development of rice sheath blight,the transcriptome profiles of the rice pls4 mutant and wild type were compared by RNA-seq.The results revealed 2,569 differentially expressed genes(DEGs).The down-regulated genes were significantly enriched in the defense response-related biological processes.These down-regulated genes included the chitinase genes and WRKY genes,which were significantly changed in pls4 mutants.Furthermore,467 genes induced significant alternative splicing(AS)events.Among them,intron retention(IR)affected gene expression levels and functions of the vitamin B6(VB6)metabolism pathway related to sheath blight.This result suggests that IR plays an important role in the sheath blight resistance of mutant pls4.Together,these results indicate that pls4 could be involved in the biological process of sheath blight via DEGs and the fine-tuning of IR.The present study provides a molecular basis for further investigation of the resistance of rice to sheath blight.

不同助留体系对装饰原纸二氧化钛复合填料留着效果的影响

本研究分别分析了单元助留体系阳离子聚酰胺环氧氯丙烷树脂(PAE),双元助留体系PAE/阴离子聚丙烯酰胺(APAM)、PAE/膨润土(MMT)、PAE/阳离子聚丙烯酰胺(CPAM),三元助留体系PAE/CPAM/APAM、PAE/CPAM/MMT对装饰原纸TiO_(2)/滑石粉复合填料留着效果的影响。确定了各个体系的最佳添加量,并筛选出助留效果最好的助留体系。结果表明,当PAE添加量2.0%、CPAM添加量0.08%、MMT添加量0.6%时,组成的PAE/CPAM/MMT三元助留体系留着效果最佳,此时,浆料和填料留着率分别为89.5%和65.0%,纸张的不透明度、白度及匀度分别为98.5%、86.6%和91。

黄精多糖提取工艺优化及其吸湿、保湿性能研究

目的:优化黄精多糖提取工艺,并研究其吸湿保湿性能、探索其护肤功能。方法:采用热回流法结合正交进行黄精多糖提取工艺优化;以黄精多糖为实验对象,采用重量法进行吸湿性(相对湿度分别为43%和81%)、保湿性试验,并对吸湿曲线进行模型拟合;将黄精多糖添加到市售面霜中进行皮肤水分测试。结果:实验表明黄精多糖最佳提取工艺条件为:料液比1∶25(g/mL),提取时间是150 min,提取次数为1次;黄精多糖在不同相对湿度下的吸湿均符合双指数模型;置于干硅胶环境下48 h,黄精多糖保湿率为14.00%。结论:黄精多糖具有良好的保湿性,在护肤品开发中具有一定的应用价值。

滇中地区主要森林凋落物有效截留量及其影响因素

[目的]研究滇中地区主要森林类型凋落物有效截留量差异及其影响因素,为该地未来植被恢复和森林管理提供科学支撑。[方法]利用样方调查法、烘干法和浸泡法分析了昆明市双河—磨南德水源林自然保护区内的地带性次生常绿阔叶林(SF)、针阔混交林(TF)、旱冬瓜林(ACF)、华山松林(PA)、成熟云南松林(OPY)、幼龄云南松林(YPY)、银荆林(AD)7种主要森林类型凋落物未分解层(OL)和半分解层(OF)的有效截留量及其影响因素。[结果](1) 7种森林类型凋落物厚度为2.06~7.57 cm,其中OL层1.10~4.30 cm, OF层0.83~3.93 cm,凋落物层厚度排序为TF>ACF>PA>OPY>SF>AD>YPY,凋落物蓄积量为4.75~17.45 t/hm^(2),其中OL层占比为32.02%~62.48%,OF层占比为37.52%~67.98%,凋落物层蓄积量排序为TF>PA>SF>OPY>ACF>AD>YPY。(2)凋落物最大持水率为115.3%~170.7%,初始吸水速率为3.65~5.62 g/(g·h),凋落物持水率和浸水时间的关系可用对数函数y=aln(x)+b表示,吸水速率与浸水时间可用幂函数y=kt~n表示。(3)凋落物最大持水量为7.05~32.19 t/hm^(2),排序为PA>TF>SF>OPY>ACF>AD>YPY,有效截留量为5.45~25.34 t/hm^(2),以TF最高(25.34t/hm^(2)),PA(24.99 t/hm^(2))和SF(24.62 t/hm^(2))次之,YPY最低(5.45t/hm^(2)),影响有效截留量的场地特征主要为蓄积量、自然含水率、分解强度以及厚度,影响有效截留量的水动力过程主要是最大失水量、前6.0 h平均吸水速率和前2.0 h平均吸水速率。[结论]滇中地区未来植树造林应以针阔混交林为主,注重对地带性次生常绿阔叶林的保育,采取辅助自然更新的措施促进人工纯林向混交林演化,同时减少踩踏、收集凋落物等人类活动的干扰,从而增加森林生态系统凋落物的水源涵养能力。

百会穴久留针法改善缺血性脑卒中小鼠神经功能的作用及机制

目的研究百会穴久留针法通过脑源性神经营养因子(BDNF)/酪氨酸受体激酶B(TrkB)通路改善缺血性脑卒中小鼠神经功能的作用及机制。方法选择雄性C57BL/6J小鼠48只,随机分为假手术1组、模型1组、久留针1组、普通留针组,每组12只。后3组采用线栓法制备缺血性脑卒中模型,手术造模后第1天起久留针1组和普通留针组分别给予百会穴久留针和普通留针治疗,连续14 d。另选择雄性C57BL/6J小鼠40只,随机分为假手术2组、模型2组、久留针2组、久留针3组,每组10只。后3组采用线栓法制备缺血性脑卒中模型,针灸治疗前分别给予腺相关病毒100μl单次尾静脉注射。采用改良神经功能缺损评分(mNSS)及水迷宫实验的逃避潜伏期、目标象限停留时间、穿越原平台次数评价神经功能。结果与假手术1组比较,模型1组mNSS评分、目标象限停留时间、穿越原平台次数及缺血脑组织BDNF、TrkB表达明显降低,细胞凋亡率及裂解型半胱氨酸天冬氨酸蛋白酶3(Caspase-3)表达明显增加,差异有统计学意义(P<0.05);与模型1组比较,久留针1组和普通留针组mNSS评分、目标象限停留时间、穿越原平台次数及缺血脑组织BDNF、TrkB表达明显增加,细胞凋亡率及裂解型Caspase-3表达明显降低,且久留针1组上述变化较普通留针组更为显著,差异有统计学意义(P<0.05)。与久留针2组比较,久留针3组mNSS评分、目标象限停留时间、穿越原平台次数及缺血脑组织中BDNF表达明显降低(P<0.05),细胞凋亡率及裂解型Caspase-3表达明显增加[(16.41±2.25)%vs(7.59±1.09)%;1.46±0.16 vs 0.94±0.12,P<0.05]。结论百会穴久留针治疗对缺血性脑卒中小鼠神经功能的改善作用更为显著,激活BDNF/TrkB通路是其发挥神经保护作用的相关分子机制。

益心泰颗粒对慢性心衰(心气虚兼血瘀水停证)大鼠AMPK、PGC-1α的影响

目的观察益心泰颗粒对慢性心力衰竭(CHF)(心气虚兼血瘀水停证)大鼠AMPK、PGC-1α的影响。方法采用丙硫氧嘧啶灌胃及阿霉素腹腔注射复制CHF(心气虚兼血瘀水停证)模型大鼠,将造模成功大鼠分为模型组与益心泰低、中、高剂量组和曲美他嗪组;另设正常对照组。灌胃4周后观察心肌组织病理结构,检测LVEF、血清NT-proBNP及心肌组织FFA、ATP/AMP、LAC、pAMPK、AMPK、PGC-1α水平。结果与模型组比较,益心泰颗粒低、中、高剂量组及曲美他嗪组LVEF、心肌组织ATP/AMP值、心肌组织p-AMPK、AMPK、PGC-1α相对灰度值均明显升高(P<0.05或P<0.01),血清NT-proBNP及心肌组织FFA、LAC明显降低(P<0.05或P<0.01)。结论益心泰颗粒能促进慢性心力衰竭(心气虚兼血瘀水停证)大鼠AMPK、PGC-1α表达,改善心肌能量代谢。

基于炉缸渣铁滞留量的高炉炉缸活性研究

针对国内外对炉缸活性表征不明晰的问题,建立以炉缸渣铁滞留量表征炉缸活性的模型,定量分析高炉操作参数对炉缸活性的作用比重,并提出提高炉缸活性的操作手段。结果表明:①渣铁焦物性对渣铁滞留率的影响顺序为:铁水温度>CSR>焦炭粒度>CRI>炉渣碱度>镁铝比;②去除滞留率对滞留量的影响,高炉操作参数对渣铁滞留量的影响顺序为:风量>铁口深度>风温>风压>喷煤量>氧气量;③高炉生产中,可采用原燃料粒级及性能管控技术、高风速大动能操作技术、渣铁流动控制技术、渣铁排放管控技术高效调控炉缸活跃状态。

面间煤柱与顺槽“掘-充-留”一体化科学问题与技术

我国将煤炭作为兜底保障能源的局面短期内无法改变,仍将长时间面临煤炭资源保护与煤基固废利用率低的难题。通过创新采掘方法,同时实现提高煤炭资源回采率、规模化处置煤基固废,为煤炭行业绿色可持续发展提供了新途径。在深入调研煤炭资源开采技术发展现状的基础上,提出了煤矿“掘-充-留”掘进新工法。从大断面巷道快速掘进、连续高效充填和巷道安全留设3个方面,通过理论分析、数值模拟等手段,系统论述了“掘-充-留”工法的科学问题和关键技术,研究结果表明:①针对大断面巷道快速掘进、掘进工作面围岩稳定性控制等工程难题,凝练了煤岩特性与掘进机截割参数匹配机制、覆岩载荷空间传递机制与围岩变形机理、锚杆/索-顶板相互作用关系及支护机制3个科学难题,构建了以掘进区地质环境超前实时感知、落-装-运煤多工序智能协同作业、钻锚支架随掘随支围岩时效控制和大断面巷道防漏风及通风优化为核心的技术体系;②从大断面巷道承载体系及时构建及其承载性能调控两个方面凝练了连续高效充填的科学问题,包括充填体-煤层-锚杆/索协同承载机制、多元固废基充填材料水化固结机制,明晰充填体物理力学特性时空演化规律,建立了充填空间安全高效搭建、充填材料工作性能调控、充填材料流动-固结感知为核心的连续高效充填关键技术体系,相关理论与技术的突破可以为充填材料的原材料优选及配比设计、添加剂开发/选型及工作性能调控、掘进速率及充填步距优化设计、充填体固结监测等提供基础理论依据;③基于巷道安全留设及全生命周期内围岩易断裂、易片帮和易损伤等关键难题,阐述了巷道围岩应力场时空分布特征、巷道变形与损伤演化机制、巷道围岩工程质量监测与稳定性调控理论3个科学问题,形成了以巷道围岩稳定性智能预警、巷道围岩变形控制为核心的关键技术体系。开展煤矿“掘-充-留”工法的科学研究与工程示范,实现固废规模化处置-面间煤柱高效回收-顺槽快速掘进的协同,可以推动煤炭行业绿色低碳转型发展。

隔附子饼灸联合生物反馈刺激对脊髓损伤后尿潴留病人膀胱功能、膀胱压力及尿路感染的影响

目的探究隔附子饼灸联合生物反馈刺激对脊髓损伤后尿潴留病人膀胱功能、膀胱压力及尿路感染的影响。方法选取河北省沧州中西医结合医院2020年6月至2022年6月收治的76例脊髓损伤后尿潴留病人进行研究,按照随机数字表法分为对照组(38例)和联合组(38例)。其中对照组给予生物反馈刺激,联合组给予隔附子饼灸联合生物反馈刺激。比较两组尿流动力学(最大膀胱压力、膀胱功能、最大膀胱测量容量),膀胱残余尿量,临床疗效,尿路感染发生率及生活自理能力。结果两组干预前、干预4周、8周后MHU评分、膀胱残余尿量依次降低(P<0.05),且干预4周、8周后,联合组[(2.45±0.26)分、(216.46±23.72)mL、(1.87±0.19)分、(114.37±11.58)mL]均明显低于对照组[(2.79±0.28)分、(242.75±26.84)mL、(2.14±0.22)分、(162.75±16.49)mL](P<0.05);两组干预前、干预4周、8周MBI评分、膀胱压力依次升高(P<0.05),且干预4周、8周后,联合组[(38.57±3.46)分、(12.67±1.27)分、(46.57±4.72)分、(14.02±1.45)分]明显高于对照组[(34.14±3.25)分、(10.96±1.14)分、(40.62±4.15)分、(12.57±1.31)分](P<0.05);联合组总有效率(89.47%)明显高于对照组(68.42%)(P<0.05),尿路感染发生率(7.89%)明显低于对照组(28.95%)(P<0.05)。结论隔附子饼灸联合生物反馈刺激对脊髓损伤后尿潴留可有效提高膀胱功能及膀胱压力,降低尿路感染及膀胱残余尿量,提升自理能力,效果较好。

延髓外侧梗死致尿潴留1例并文献复习

延髓外侧梗死是常见的脑干梗死综合征之一,但在临床上其导致尿潴留的病例并不多见。本文回顾性分析山东中医药大学第二附属医院收治的延髓外侧梗死致尿潴留的患者1例,患者以头晕、行走不稳为主要症状,同时发现存在急性尿潴留的临床表现,完善影像学检查后诊断为延髓外侧梗死;神经源性膀胱(尿潴留)。及时予以患者静脉溶栓、导尿及其他对症治疗,约1个月后其自主排尿功能完全恢复。尽管延髓外侧梗死导致尿潴留的病例不常见,但应充分了解并提高对此类情况的认知,做到全面预判,提前告知患者及其家属尿潴留的可能性及其预后,反之,在颅脑CT显示不佳、MRI完善不及时的情况下,对于眩晕症状明显而其他定位体征较少,同时又合并急性尿潴留的患者,也能给予脑干-延髓外侧部分-可能受损的提示,提高对后循环梗死的警惕和重视,给予及时、适当的处理,避免延治失治。