This case is of Rh -ve 2nd gravida having antibody titre detected 1:2 at 8 weeks of 2nd pregnancy. Serial antibody titre carried out along with clinical examination. Fetal monitoring was done by assessing MCA-PSV (Mid...This case is of Rh -ve 2nd gravida having antibody titre detected 1:2 at 8 weeks of 2nd pregnancy. Serial antibody titre carried out along with clinical examination. Fetal monitoring was done by assessing MCA-PSV (Middle cerebral artery peak systolic velocity) and CTG (Cardiotocograph) when required. Pregnancy was terminated when the titre reached 1:512 at 34 wks of pregnancy with abnormal MCA-PSV values. Neonate just had begun to show sign of anaemia & haemolysis at birth.展开更多
A 39-year-old 34-week-pregnant woman was referred to our hospital for preterm labor and fetal dysfunction. Fetal middle cerebral artery systolic maximum blood flow velocity was high, so fetal anemia was suspected. Blo...A 39-year-old 34-week-pregnant woman was referred to our hospital for preterm labor and fetal dysfunction. Fetal middle cerebral artery systolic maximum blood flow velocity was high, so fetal anemia was suspected. Blood type was O-type Rh (+) and fetal hemoglobin was 0.4%;tests for irregular antibody and human parvovirus B19 IgM were negative. A high brightness echoic mass was observed in fetal stomach bubble, and amniotic fluid appeared bright. Labor suppression was disabled, and emergency cesarean section was performed. Amniotic fluid turbidity was observed, and on suctioning the stomach content of the infant, turbid amniotic fluid containing blood was obtained. On placental pathological examination, the cause of bloody amniotic fluid was not identified. The infant’s hemoglobin level was low at 8.7 g/dL, so the infant received red cell concentrate, with improvement of general condition.展开更多
目的探讨多普勒超声测量胎儿大脑中动脉峰值流速(MCA-PSV)技术联合胎儿血红蛋白(HbF)酸洗脱试验(K le ihauer-Betke test,KBT)用于预测胎母输血综合征(FMH)所致胎儿贫血的临床应用价值。方法选取本院于2008年7月—2009年7月间,收治的16...目的探讨多普勒超声测量胎儿大脑中动脉峰值流速(MCA-PSV)技术联合胎儿血红蛋白(HbF)酸洗脱试验(K le ihauer-Betke test,KBT)用于预测胎母输血综合征(FMH)所致胎儿贫血的临床应用价值。方法选取本院于2008年7月—2009年7月间,收治的164例由孕妇主诉胎动减少或消失等、怀疑FMH且孕周>32周的病例,记录MCA-PSV并获取母血进行KBT;以MCA-PSV高于均数1.5倍和HbF在母血中比例>3%为阳性指标。结果164例病例中,KBT阳性20例(12.2%),MCA-PSV阳性8例(4.9%);临床确诊为FMH致胎儿贫血8例(4.9%),该8例KBT均阳性,其中6例(75%)联合检测阳性。结论多普勒超声测量MCA-PSV联合HbF检测有助于提高FMH所致胎儿贫血诊断的特异性,是及时诊治FMH所致急性胎儿贫血的重要方法。展开更多
文摘This case is of Rh -ve 2nd gravida having antibody titre detected 1:2 at 8 weeks of 2nd pregnancy. Serial antibody titre carried out along with clinical examination. Fetal monitoring was done by assessing MCA-PSV (Middle cerebral artery peak systolic velocity) and CTG (Cardiotocograph) when required. Pregnancy was terminated when the titre reached 1:512 at 34 wks of pregnancy with abnormal MCA-PSV values. Neonate just had begun to show sign of anaemia & haemolysis at birth.
文摘A 39-year-old 34-week-pregnant woman was referred to our hospital for preterm labor and fetal dysfunction. Fetal middle cerebral artery systolic maximum blood flow velocity was high, so fetal anemia was suspected. Blood type was O-type Rh (+) and fetal hemoglobin was 0.4%;tests for irregular antibody and human parvovirus B19 IgM were negative. A high brightness echoic mass was observed in fetal stomach bubble, and amniotic fluid appeared bright. Labor suppression was disabled, and emergency cesarean section was performed. Amniotic fluid turbidity was observed, and on suctioning the stomach content of the infant, turbid amniotic fluid containing blood was obtained. On placental pathological examination, the cause of bloody amniotic fluid was not identified. The infant’s hemoglobin level was low at 8.7 g/dL, so the infant received red cell concentrate, with improvement of general condition.
文摘目的探讨多普勒超声测量胎儿大脑中动脉峰值流速(MCA-PSV)技术联合胎儿血红蛋白(HbF)酸洗脱试验(K le ihauer-Betke test,KBT)用于预测胎母输血综合征(FMH)所致胎儿贫血的临床应用价值。方法选取本院于2008年7月—2009年7月间,收治的164例由孕妇主诉胎动减少或消失等、怀疑FMH且孕周>32周的病例,记录MCA-PSV并获取母血进行KBT;以MCA-PSV高于均数1.5倍和HbF在母血中比例>3%为阳性指标。结果164例病例中,KBT阳性20例(12.2%),MCA-PSV阳性8例(4.9%);临床确诊为FMH致胎儿贫血8例(4.9%),该8例KBT均阳性,其中6例(75%)联合检测阳性。结论多普勒超声测量MCA-PSV联合HbF检测有助于提高FMH所致胎儿贫血诊断的特异性,是及时诊治FMH所致急性胎儿贫血的重要方法。
