The nuclides inhaled during nuclear accidents usually cause internal contamination of the lungs with low activity.Although a parallel-hole imaging system,which is widely used in medical gamma cameras,has a high resolu...The nuclides inhaled during nuclear accidents usually cause internal contamination of the lungs with low activity.Although a parallel-hole imaging system,which is widely used in medical gamma cameras,has a high resolution and good image quality,owing to its extremely low detection efficiency,it remains difficult to obtain images of inhaled lung contamination.In this study,the Monte Carlo method was used to study the internal lung contamination imaging using the MPA-MURA coded-aperture collimator.The imaging system consisted of an adult male lung model,with a mosaicked,pattern-centered,and anti-symmetric MURA coded-aperture collimator model and a CsI(Tl)detector model.The MLEM decoding algorithm was used to reconstruct the internal contamination image,and the complementary imaging method was used to reduce the number of artifacts.The full width at half maximum of the I-131 point source image reconstructed by the MPAMURA coded-aperture imaging reached 2.51 mm,and the signal-to-noise ratio of the simplified respiratory tract source(I-131)image reconstructed through MPA-MURA coded-aperture imaging was 3.98 dB.Although the spatial resolution of MPA-MURA coded-aperture imaging is not as good as that of parallel-hole imaging,the detection efficiency of PMA-MURA coded-aperture imaging is two orders of magnitude higher than that of parallel-hole collimator imaging.Considering the low activity level of internal lung contamination caused by nuclear accidents,PMA-MURA coded-aperture imaging has significant potential for the development of lung contamination imaging.展开更多
Since the coded aperture technique has been successfully applied on X-ray imaging space telescopes, attentions of its development have also been cast on the application in medical imaging, for it has a very tempting q...Since the coded aperture technique has been successfully applied on X-ray imaging space telescopes, attentions of its development have also been cast on the application in medical imaging, for it has a very tempting quality to greatly enhance the detection sensitivity without gravely lowering the spacial resolution. But when the coded aperture technique is applied to image a nearby object, the so called ＂near-field artifact＂ comes up, that is, the reconstructed image has a sort of distortion. Among types of coded apertures the MURA （Modified Uniformly Redundant Array） is one of the most discussed. Roberto Arrcosi came up with the solution to remove the artifacts utilizing mask and antimask. In this article we present two ways to eliminate the second order aberration based on his work.展开更多
基金the Ministry of Science and Technology,People’s Republic of China(No.2012YQ180118)the National Natural Science Foundation of China(No.41874121)the Sichuan Science and Technology Program(No.2018JY0181).
文摘The nuclides inhaled during nuclear accidents usually cause internal contamination of the lungs with low activity.Although a parallel-hole imaging system,which is widely used in medical gamma cameras,has a high resolution and good image quality,owing to its extremely low detection efficiency,it remains difficult to obtain images of inhaled lung contamination.In this study,the Monte Carlo method was used to study the internal lung contamination imaging using the MPA-MURA coded-aperture collimator.The imaging system consisted of an adult male lung model,with a mosaicked,pattern-centered,and anti-symmetric MURA coded-aperture collimator model and a CsI(Tl)detector model.The MLEM decoding algorithm was used to reconstruct the internal contamination image,and the complementary imaging method was used to reduce the number of artifacts.The full width at half maximum of the I-131 point source image reconstructed by the MPAMURA coded-aperture imaging reached 2.51 mm,and the signal-to-noise ratio of the simplified respiratory tract source(I-131)image reconstructed through MPA-MURA coded-aperture imaging was 3.98 dB.Although the spatial resolution of MPA-MURA coded-aperture imaging is not as good as that of parallel-hole imaging,the detection efficiency of PMA-MURA coded-aperture imaging is two orders of magnitude higher than that of parallel-hole collimator imaging.Considering the low activity level of internal lung contamination caused by nuclear accidents,PMA-MURA coded-aperture imaging has significant potential for the development of lung contamination imaging.
文摘Since the coded aperture technique has been successfully applied on X-ray imaging space telescopes, attentions of its development have also been cast on the application in medical imaging, for it has a very tempting quality to greatly enhance the detection sensitivity without gravely lowering the spacial resolution. But when the coded aperture technique is applied to image a nearby object, the so called ＂near-field artifact＂ comes up, that is, the reconstructed image has a sort of distortion. Among types of coded apertures the MURA （Modified Uniformly Redundant Array） is one of the most discussed. Roberto Arrcosi came up with the solution to remove the artifacts utilizing mask and antimask. In this article we present two ways to eliminate the second order aberration based on his work.
