Stability of the Stratification of Water Bodies in the North Passage of the Yangtze River Estuary Based on the EFDC Model

To study the stratified stability of a water column in the North Passage of the Yangtze River Estuary,a numerical model of the hydrodynamics of this estuary is established using the EFDC model.On the basis of EFDC results,this paper derives and pro-vides the discriminative index of water body stability caused by salinity and analyzes the along-range variation in water body strati-fication stability in the North Passage of the Yangtze River Estuary and the periodic variation at a key location(bend area)based on the simulation results of the numerical model.This work shows that the water body in the bend area varies between mixed and strati-fied types,and the vertical average flow velocity has a good negative correlation with the differential velocity between the surface and bottom layers of the water body.The model simulation results validate the formulae for the stratified stability discriminant during spring tides.

Effects of high glucose and severe hypoxia on the biological behavior of mesenchymal stem cells at various passages

BACKGROUND Mesenchymal stem cells(MSCs)have been extensively studied for therapeutic potential,due to their regenerative and immunomodulatory properties.Serial passage and stress factors may affect the biological characteristics of MSCs,but the details of these effects have not been recognized yet.AIM To investigate the effects of stress factors(high glucose and severe hypoxia)on the biological characteristics of MSCs at different passages,in order to optimize the therapeutic applications of MSCs.METHODS In this study,we investigated the impact of two stress conditions;severe hypoxia and high glucose on human adipose-tissue derived MSCs(hAD-MSCs)at passages 6(P6),P8,and P10.Proliferation,senescence and apoptosis were evaluated measuring WST-1,senescence-associated beta-galactosidase,and annexin V,respectively.RESULTS Cells at P6 showed decreased proliferation and increased apoptosis under conditions of high glucose and hypoxia compared to control,while the extent of senescence did not change significantly under stress conditions.At P8 hAD-MSCs cultured in stress conditions had a significant decrease in proliferation and apoptosis and a significant increase in senescence compared to counterpart cells at P6.Cells cultured in high glucose at P10 had lower proliferation and higher senescence than their counterparts in the previous passage,while no change in apoptosis was observed.On the other hand,MSCs cultured under hypoxia showed decreased senescence,increased apoptosis and no significant change in proliferation when compared to the same conditions at P8.CONCLUSION These results indicate that stress factors had distinct effects on the biological processes of MSCs at different passages,and suggest that senescence may be a protective mechanism for MSCs to survive under stress conditions at higher passage numbers.

Factors and Cut-Off Predicting Stone Passage under Medical Expulsive Therapy (MET)

Background: Ureteral stones are the most common leading cause of acute flank pain. This study aimed to identify sociodemographic and clinical variables predicting spontaneous ureteral stone passage and determine the optimal size cut-off for predicting such passage. Method: We conducted a retrospective evaluation of patients presenting with acute renal colic at a urology outpatient clinic. Patients with ureteral stones ≤ 10 mm and no surgical intervention post-initial diagnosis, who attended follow-up visits, were included. Exclusion criteria comprised stone size > 1 cm, fever due to obstructive pyelonephritis, acute kidney injury, single kidney status, or bilateral ureteral obstruction. Results: Of 124 included patients, the spontaneous stone passage rate was 57.3%, with a mean passage time of 11.1 (SD 6.25) days. Bivariate analysis revealed that factors predicting spontaneous passage were stone size (p Conclusions: Stone size < 7 mm, UVJ or distal ureter location, emerged as key predictors of stone passage in nephrolithiasis, and stone size below 6.85 mm is a reasonable cut off to initiate MET rather than 10 mm.

高速公路收费站ETC/MTC混合收费车道通行能力计算模型研究

分析了ETC/MTC混合收费车道入口ETC车辆占比αE和连续到达ETC车辆排队长度w对混合收费车道平均服务时间tS的影响;对SHAKER模型进行了修正,并对修正SHAKER模型参数进行了标定,建立VISSIM仿真模型对修正SHAKER模型的有效性进行了验证;分析了ETC/MTC混合收费车道通行能力与ETC车辆占比之间的关系,提出了考虑车辆平均服务时间的ETC/MTC混合收费车道入口通行能力估计模型,并与余弦函数模型进行了对比分析。结果表明:不同ETC车辆占比下,ETC/MTC混合收费车道入口通行能力修正SHAKER模型计算值和VISSIM模型仿真值的相对误差ε<10%,在允许范围之内,验证了修正SHAKER模型的有效性;ETC/MTC混合收费车道通行能力随着驶入混合车道ETC车辆占比的增大而增大;与余弦函数模型相比,笔者提出的估计模型更能反映ETC/MTC混合收费车道的交通运行特性。

面向Critical MTC的无连接传输

关键机器类通信(Critical MTC)对时延和可靠性都有极高的要求。支持海量Critical MTC的终端是一个巨大挑战。提出了一种面向海量Critical MTC终端的无连接传输方案。为了降低时延,提出了基于竞争的无连接单次传输方案;为了实现高可靠性,设计了具有极低导频碰撞概率的稀疏正交多导频。进一步利用大规模多输入多输出(MIMO)的增益来提高可靠性以及在空域复用大量用户。仿真结果表明,提出的方案可以支持海量Critical MTC终端,同时满足低时延和高可靠的严格要求。

Development potential of the Northeast Passage based on a multinomial-logit-based stochastic user equilibrium model

We developed a multinomial-logit-based stochastic user equilibrium(MNL SUE)model incorporating time value of cargo to investigate future proportions of cargo flow through the Northeast Passage(NEP)and the Suez Canal Route between representative ports.We studied navigation during the ice-free and ice-covered seasons using sea ice projections for 2070 based on 1991–2021 NEP ice data.Sailing distance and time between selected ports are lower via the NEP than the Suez Canal Route.Under the scenario of year-round operation of the NEP,the proportion of cargo flow through the NEP is estimated to be 68.5%,which represents considerable commercial potential.Proportions are higher for the ice-free season and for ports at high latitudes.We also assessed flow under different scenarios.Under the scenario of fuel price increase,proportion of flow through the NEP in the ice-covered season is expected to increase.If time value is ignored,flow through the NEP is expected to increase all year round.If shippers become more cost-conscious,flow through the NEP is also expected to increase.

《詩經》的國際化:域外漢學家呈現的光陰推移(temporal passage)和心理反應

一、引言《詩經》之中,“慆慆”指時間長久的感覺。“慆”用作動詞,指逝去,意思與“滔”同((1))。書中表示一天内的時間用語有:昧、旦、夙、朝、辰、晝、莫、昏、夕、宵、夜((2))。這些詞語都不能指涉很精確的時刻。不過,周王朝可能有洩水型計時器——漏壺((3))。到了春秋時代,墨家有計時之學((4))。東漢王充《論衡》記載了“日(太陽)行天十六道”。先秦時期,民衆没有自鳴鐘.

Connection-Free Transmission for Critical MTC

In this paper,a contention-based connection-free transmission scheme is proposed to meet the stringent requirements of ultra-reliability and low-latency for critical machine-type communication(cMTC).To improve reliability,we design multiple independent sparse orthogonal pilots(MISOP)to significantly reduce the probability of pilot collision to the order of 10^(−5).Besides,the advancements of massive MIMO(mMIMO)are exploited to further enhance the reliability.To achieve low latency,connection-free slot-based one-shot transmission without retransmissions is adopted.On the receiver side,single round of multi-user detection(MUD)without interference cancellation(IC)can reduce the processing delay.The imprecise synchronization between cMTC device and the gNB in connection-free transmission,e.g.,time and frequency offsets,are also considered.The simulation results shows that the proposed scheme can well satisfy the ambitious requirements of cMTC,and has the potential applications in supporting massive cMTC devices in 6G.

基于ETC与MTC的高速OD及轨迹获取与应用

随着省界收费站撤消以及ETC的普及,高速OD及轨迹正成为研究热点。为了获得高速OD及轨迹,针对ETC数据,假设路段缺失少,通过路段首尾与最短路连接建立了一种独立于通行时间,且又能补齐缺失路段的轨迹获取方法;针对MTC数据,补齐因为省界收费站撤销而导致的OD缺失。分析了G2安亭收费站与奉贤新城相关的高速OD及轨迹分布,特别是指定区域的内部、到发和途经的高速OD、轨迹与断面流量,能为区域交通规划以及测算区域车辆出行总量与分布提供依据。

基于强化学习的MTC随机接入和异构网络资源分配方法研究

随着技术的不断发展,为了进一步提高交通运输效率,ITS需要使用不同的技术进行管理。在此方面,基于蜂窝移动通信的随机接入机制是一种有效的解决方案。然而,由于异构网络、复杂的传输环境和不确定的用户行为等因素,在无线通信中使用RAM方案时存在很多问题。因此,文章提出了一种基于强化学习的联合资源分配方法来解决这些问题。

Failure of Aspired Understanding Among the Human Race——On the Theme of A Passage to India

The author attempts to interpret the theme of A Passsage to India by analyzing the major events and characterization. It is indicated in the thesis that E.M.Forster highlights the failure of aspired understanding between different races, different people and even within a person. In other words, in many cases people have aspirations for understanding, but in reality the real understanding is very difficult to fulfill.

An Analysis of the Performance of Orientalism in A Passage to India and the Exorcization of Orientalism in Maxine Hong Kingston's Works

This thesis tries to study two novels:firstly,the performance of Orientalism in the novel A Passage to India;secondly the Exorcization of Orientalism in the novel the Woman Warrior written by Maxine Hong Kingston.

一种固定位置MTC设备的随机接入改进算法

针对海量机器类通信(Massive Machine Type Communications,mMTC)场景下传统随机接入存在大量前导碰撞问题,提出了一种对终端侧和基站侧的接入改进算法,利用前导标记序列和固定位置随机接入终端的定时提前(Timing Advance,TA)信息,使得基站能合理地确定应该向哪些终端回复随机接入响应消息,避免碰撞终端占用资源发送消息3(Message 3,Msg3),实现前导高效利用。仿真表明,该算法在均匀分布和Beta分布接入模型下均能有效降低前导碰撞概率,提高终端的接入成功率,并且拥有合理的平均接入时延。

The Conflict and Unity in A Passage to India

Forster attaches much importance to the relationship among people in his works.In A Passage to India,the topic of conflict and unity is discussed in depth,including man and man&man and nature.The passage will represent conflict and unity by introduction to the writer and analysis to his work.

Effects of Meridional Flow Passage Shape on Hydraulic Performance of Mixed-flow Pump Impellers

During the process of designing the mixed-flow pump impeller, the meridional flow passage shape directly affects the obtained meridional flow field, which then has an influence on the three-dimensional impeller shape. However, the meridional flow passage shape is too complicated to be described by a simple formula for now. Therefore, reasonable parameter selection for the meridional flow passage is essential to the investigation. In order to explore the effects of the meridional flow passage shape on the impeller design and the hydraulic performance of the mixed-flow pump, the hub and shroud radius ratio (HSRR) of impeller and the outlet diffusion angle (ODA) of outlet zone are selected as the meridional flow passage parameters. 25 mixed-flow pump impellers, with specific speed of 496 under the design condition, are designed with various parameter combinations. Among these impellers, one with HSRR of 1.94 and ODA of 90° is selected to carry out the model test and the obtained experimental results are used to verify accuracies of the head and the hydraulic efficiency predicted by numerical simulation. Based on SIMPLE algorithm and standard k-ε two-equation turbulence model, the three-dimensional steady incompressible Reynolds averaged Navier-Stokes equations are solved and the effects of different parameters on hydraulic performance of mixed-flow pump impellers are analyzed. The analysis results demonstrate that there are optimal values of HSRR and ODA available, so the hydraulic performance and the internal flow of mixed-flow pumps can be improved by selecting appropriate values for the meridional flow passage parameters. The research on these two parameters, HSRR and ODA, has further illustrated influences of the meridional flow passage shape on the hydraulic performance of the mixed-flow pump, and is beneficial to improving the design of the mixed-flow pump impeller.

Changes in sea ice kinematics in the Arctic outflow region and their associations with Arctic Northeast Passage accessibility

Amplification of climate warming in the Arctic is causing a dramatic retreat of sea ice, which means the Arctic sea routes are becoming increasingly accessible. This study used a satellite-derived sea ice motion product to quantify the kinematic features of sea ice in the Arctic outflow region which specially referred to the Fram Strait and to the north of the Northeast Passage(NEP). An observed trend of increased southward sea ice displacement from the central Arctic to the Fram Strait indicated enhancement of the Transpolar Drift Stream(TDS). In the regions to the north of the NEP, the long-term trend of northward sea ice speed in the Kara sector was +0.04 cm/s per year in spring. A significant statistical relationship was found between the NEP open period and the northward speed of the sea ice to the north of the NEP. The offshore advection of sea ice could account for the opening of sea routes by 33% and 15% in the Kara and Laptev sectors, respectively. The difference in sea level pressure across the TDS,i.e., the Central Arctic Index(CAI), presented more significant correlation than for the Arctic atmospheric Dipole Anomaly index with the open period of the NEP, and the CAI could explain the southward displacement of sea ice toward the Fram Strait by more than 45%. The impact from the summer positive CAI reinforces the thinning and mechanical weakening of the sea ice in the NEP region, which improves the navigability of the NEP.

Anisodamine accelerates spontaneous passage of single symptomatic bile duct stones ≤ 10 mm

AIM:To investigate the rate of spontaneous passage of single and symptomatic common bile duct(CBD)stones≤10 mm in diameter in 4 wk with or without a2-wk course of anisodamine.METHODS:A multicenter,randomized,placebocontrolled trial was undertaken.A total of 197 patients who met the inclusion criteria were enrolled.Ninetyseven patients were assigned randomly to the control group and the other 100 to the anisodamine group.The anisodamine group received intravenous infusions of anisodamine(10 mg every 8 h)for 2 wk.The control group received the same volume of 0.9%isotonic saline for 2 wk.Patients underwent imaging studies and liver-function tests every week for 4 wk.The rate of spontaneous passage of CBD stones was analyzed.RESULTS:The rate of spontaneous passage of CBD stones was significantly higher in the anisodamine group than that in the control group(47.0%vs 22.7%).Most(87.2%,41/47)stone passages in the anisodamine group occurred in the first 2 wk,and passages in the control group occurred at a comparable rate each week.Factors significantly increasing the possibility of spontaneous passage by univariate logistic regression analyses were stone diameter(<5 mm vs≥5 mm and≤10 mm)and anisodamine therapy.Multivariate logistic regression analyses revealed that these two factors were significantly associated with spontaneous passage.CONCLUSION:Two weeks of anisodamine administration can safely accelerate spontaneous passage of single and symptomatic CBD stones≤10 mm in diameter,especially for stones<5 mm.

Optimization of transport passage with dragline system in thick overburden open pit mine

According to the characteristics of opencast coal resources and dragline technology system application in China,the structure and shifting step of transport passage are optimized in this paper.Typical coal transport passage is analyzed in aspects such as the internal dump occupation,dragline operation efficiency,coal transport distance,upper stripping distance and shifting quantities.The middle passage should be given priority in thick overburden open pit mine because the dragline system is only responsible for part stripping task.According to characteristics of middle passage,the transport passage is divided into parallel climbing,vertical climbing and horizontal transport.In addition,the transport passage structure optimization model and shifting distance optimization model are established in this paper.The case study in Heidaigou open pit mine shows that,the parallel climbing height is accounted for about 60%of the total height,and reasonable shifting distances of the first mining area and the second mining area are 240 and 320 m.Sensitivity analysis shows that,the total passage height has important influence on the shifting step,so it is with the stripping height and passage construction cost to the passage structure.

Experimental Study of the Influence of Flow Passage Subtle Variation on Mixed-flow Pump Performance

In the mixed-flow pump design, the shape of the flow passage can directly affect the flow capacity and the internal flow, thus influencing hydraulic performance, cavitation performance and operation stability of the mixed-flow pump. However, there is currently a lack of experimental research on the influence mechanism. Therefore, in order to analyze the effects of subtle variations of the flow passage on the mixed-flow pump performance, the frustum cone surface of the end part of inlet contraction flow passage of the mixed-flow pump is processed into a cylindrical surface and a test rig is built to carry out the hydraulic performance experiment. In this experiment, parameters, such as the head, the efficiency, and the shaft power, are measured, and the pressure fluctuation and the noise signal are also collected. The research results suggest that after processing the inlet flow passage, the head of the mixed-flow pump significantly goes down; the best efficiency of the mixed-flow pump drops by approximately 1.5%, the efficiency decreases more significantly under the large flow rate; the shaft power slightly increases under the large flow rate, slightly decreases under the small flow rate. In addition, the pressure fluctuation amplitudes on both the impeller inlet and the diffuser outlet increase significantly with more drastic pressure fluctuations and significantly lower stability of the internal flow of the mixed-flow pump. At the same time, the noise dramatically increases. Overall speaking, the subtle variation of the inlet flow passage leads to a significant change of the mixed-flow pump performance, thus suggesting a special attention to the optimization of flow passage. This paper investigates the influence of the flow passage variation on the mixed-flow pump performance by experiment, which will benefit the optimal design of the flow passage of the mixed-flow pump.