Magnesium ion batteries(MIBs)are a potential field for the energy storage of the future but are restricted by insufficient rate capability and rapid capacity degradation.Magnesium-sodium hybrid ion batteries(MSHBs)are...Magnesium ion batteries(MIBs)are a potential field for the energy storage of the future but are restricted by insufficient rate capability and rapid capacity degradation.Magnesium-sodium hybrid ion batteries(MSHBs)are an effective way to address these problems.Here,we report a new type of MSHBs that use layered sodium vanadate((Na,Mn)V_(8)O_(20)·5H_(2)O,Mn-NVO)cathodes coupled with an organic 3,4,9,10-perylenetetracarboxylic diimide(PTCDI)anode in Mg^(2+)/Na^(+)hybrid electrolytes.During electrochemical cycling,Mg^(2+)and Na^(+)co-participate in the cathode reactions,and the introduction of Na^(+)promotes the structural stability of the Mn-NVO cathode,as cleared by several ex-situ characterizations.Consequently,the Mn-NVO cathode presents great specific capacity(249.9 mA h g^(−1)at 300 mA g^(−1))and cycling(1500 cycles at 1500 mA g^(−1))in the Mg^(2+)/Na^(+)hybrid electrolytes.Besides,full battery displays long lifespan with 10,000 cycles at 1000 mA g^(−1).The rate performance and cycling stability of MSHBs have been improved by an economical and scalable method,and the mechanism for these improvements is discussed.展开更多
Background:Magnesium cantharidate(MC)is a protein phosphatase 2A(PP2A)inhibitor antitumor drug.However,its antitumor mechanism in hepatocellular carcinoma cell(HCC)remains unclear.Methods:PP2A lentiviral vector over e...Background:Magnesium cantharidate(MC)is a protein phosphatase 2A(PP2A)inhibitor antitumor drug.However,its antitumor mechanism in hepatocellular carcinoma cell(HCC)remains unclear.Methods:PP2A lentiviral vector over expression strategy was utilized both in vivo and in vitro to explore the antitumor effect in MC and okadaic acid(OA).Tumor weight was detected in mice after MC and OA exposure.Cell proliferation,cell cycle,apoptosis rate,and western blotting were detected to explore the effects on MC and OA in human hepatocarcinoma SMMC-7721 cells.Results:In vivo results demonstrated that MC inhibited HCC progression while OA promoted tumor growth.In vitro results demonstrated that MC effectively inhibited the growth of SMMC-7721 cells by arresting the cell cycle at the G2/M phase with inhibiting Cdc25C and activating the phosphorylation of the Cdc2 protein.Flow cytometry results further showed that MC increased apoptosis.Furthermore,the expression of phosphorylated ERK1/2 was lower in the MC group but higher in the OA group.Molecular docking results showed that MC docked well with ERK1/2.Conclusions:MC inhibited HCC progression by suppressing the growth and activating the apoptosis of cancer cells and suppressing the expression of PP2A and ERK1/2.展开更多
针对AZ31镁合金作为镁电池负极时存在自腐蚀速率大、阳极极化、电位滞后等问题,寻找合适的缓蚀剂及其用量调配电解液以提高电池的放电性能。通过腐蚀浸泡试验表征了缓蚀剂Li_(2)CrO_(4)的缓蚀效果,然后通过极化曲线、电化学阻抗谱研究了...针对AZ31镁合金作为镁电池负极时存在自腐蚀速率大、阳极极化、电位滞后等问题,寻找合适的缓蚀剂及其用量调配电解液以提高电池的放电性能。通过腐蚀浸泡试验表征了缓蚀剂Li_(2)CrO_(4)的缓蚀效果,然后通过极化曲线、电化学阻抗谱研究了Mg(ClO_(4))_(2)溶液中Li_(2)CrO_(4)用量对AZ31镁合金电化学性能的影响,最后通过组装水系镁锰电池进行恒流放电作为应用端测试。结果表明:Li_(2)CrO_(4)能够使AZ31镁合金的腐蚀电位正移,最大正移量达到150 m V,在水系镁锰电池应用中能够提高镁电池的放电平台,当Li_(2)CrO_(4)质量分数为0.7%时放电平台提高0.15 V左右;当Li_(2)CrO_(4)质量分数为1.2%时,其能够显著改善AZ31镁合金在Mg(ClO_(4))_(2)溶液中的腐蚀,水系镁锰电池放电容量达最大,为196.9 m A·h,相对空白溶液,电池的放电容量提高约64%,工作电压高达1.39 V且放电曲线稳定。展开更多
基金the financial support from the National Natural Science Foundation of China, China (22005207, 52261160384)the Guangdong Basic and Applied Basic Research Foundation, Guangdong Province, China (2019A1515011819)+2 种基金the Outstanding Youth Basic Research Project of Shenzhen, Shenzhen, China (RCYX20221008092934093)the Joint Funds of the National Natural Science Foundation of China, China (U22A20140)the Science and Technology Development Fund, Macao SAR (0090/2021/A2 and 0049/2021/AGJ)
文摘Magnesium ion batteries(MIBs)are a potential field for the energy storage of the future but are restricted by insufficient rate capability and rapid capacity degradation.Magnesium-sodium hybrid ion batteries(MSHBs)are an effective way to address these problems.Here,we report a new type of MSHBs that use layered sodium vanadate((Na,Mn)V_(8)O_(20)·5H_(2)O,Mn-NVO)cathodes coupled with an organic 3,4,9,10-perylenetetracarboxylic diimide(PTCDI)anode in Mg^(2+)/Na^(+)hybrid electrolytes.During electrochemical cycling,Mg^(2+)and Na^(+)co-participate in the cathode reactions,and the introduction of Na^(+)promotes the structural stability of the Mn-NVO cathode,as cleared by several ex-situ characterizations.Consequently,the Mn-NVO cathode presents great specific capacity(249.9 mA h g^(−1)at 300 mA g^(−1))and cycling(1500 cycles at 1500 mA g^(−1))in the Mg^(2+)/Na^(+)hybrid electrolytes.Besides,full battery displays long lifespan with 10,000 cycles at 1000 mA g^(−1).The rate performance and cycling stability of MSHBs have been improved by an economical and scalable method,and the mechanism for these improvements is discussed.
基金The research was financially supported by the National Natural Science Foundation of China(no.81760746)Science and Technology Department of Zunyi city of Guizhou province of China([2020]7)Guizhou Provincial Science&Technology Program(ZK[2022]615).
文摘Background:Magnesium cantharidate(MC)is a protein phosphatase 2A(PP2A)inhibitor antitumor drug.However,its antitumor mechanism in hepatocellular carcinoma cell(HCC)remains unclear.Methods:PP2A lentiviral vector over expression strategy was utilized both in vivo and in vitro to explore the antitumor effect in MC and okadaic acid(OA).Tumor weight was detected in mice after MC and OA exposure.Cell proliferation,cell cycle,apoptosis rate,and western blotting were detected to explore the effects on MC and OA in human hepatocarcinoma SMMC-7721 cells.Results:In vivo results demonstrated that MC inhibited HCC progression while OA promoted tumor growth.In vitro results demonstrated that MC effectively inhibited the growth of SMMC-7721 cells by arresting the cell cycle at the G2/M phase with inhibiting Cdc25C and activating the phosphorylation of the Cdc2 protein.Flow cytometry results further showed that MC increased apoptosis.Furthermore,the expression of phosphorylated ERK1/2 was lower in the MC group but higher in the OA group.Molecular docking results showed that MC docked well with ERK1/2.Conclusions:MC inhibited HCC progression by suppressing the growth and activating the apoptosis of cancer cells and suppressing the expression of PP2A and ERK1/2.
文摘【目的】研究镁橄榄石掺加对减轻超临界CO_(2)环境下油井水泥石的腐蚀渗透性能。【方法】以镁橄榄石粉为外掺料配制不同的油井水泥,分析温度为150℃,CO_(2)总压为50 MPa条件下镁橄榄石水泥石的抗压强度,优选出镁橄榄石粉的最佳掺量;利用渗透率、热重分析(thermo gravimetric analysis,TGA)、X射线衍射(X-Ray diffraction,XRD)和扫描电子显微镜(scanning electron microscope,SEM)进行测试,评价镁橄榄石对油井水泥石抗CO_(2)腐蚀性能的影响,分析镁橄榄石对油井水泥石抗CO_(2)腐蚀的作用机制。【结果】镁橄榄石粉的掺入不会影响油井水泥的流动度,当镁橄榄石粉的质量分数为2%时,对比腐蚀前油井水泥石的,抗压强度提高35.47%,渗透率降低0.0104 m D;腐蚀28 d后,镁橄榄石水泥石的抗压强度为空白水泥石的193.71%,且仍高于腐蚀前。【结论】镁橄榄石是一种抗CO_(2)腐蚀外加剂,能提升油井水泥的抗CO_(2)腐蚀性能。
文摘针对AZ31镁合金作为镁电池负极时存在自腐蚀速率大、阳极极化、电位滞后等问题,寻找合适的缓蚀剂及其用量调配电解液以提高电池的放电性能。通过腐蚀浸泡试验表征了缓蚀剂Li_(2)CrO_(4)的缓蚀效果,然后通过极化曲线、电化学阻抗谱研究了Mg(ClO_(4))_(2)溶液中Li_(2)CrO_(4)用量对AZ31镁合金电化学性能的影响,最后通过组装水系镁锰电池进行恒流放电作为应用端测试。结果表明:Li_(2)CrO_(4)能够使AZ31镁合金的腐蚀电位正移,最大正移量达到150 m V,在水系镁锰电池应用中能够提高镁电池的放电平台,当Li_(2)CrO_(4)质量分数为0.7%时放电平台提高0.15 V左右;当Li_(2)CrO_(4)质量分数为1.2%时,其能够显著改善AZ31镁合金在Mg(ClO_(4))_(2)溶液中的腐蚀,水系镁锰电池放电容量达最大,为196.9 m A·h,相对空白溶液,电池的放电容量提高约64%,工作电压高达1.39 V且放电曲线稳定。
