Objective The purpose of the study was to investigate the effective parameters of electric cortex stimulation (ECS) for functional brain mapping. Methods We collected 21 subjects who underwent epilepsy surgeries conse...Objective The purpose of the study was to investigate the effective parameters of electric cortex stimulation (ECS) for functional brain mapping. Methods We collected 21 subjects who underwent epilepsy surgeries consecutively in Beijing Institute of Functional Neurosurgery with the epileptogenic zone located in perirolandic areas from展开更多
In this paper, we analyze the physical layer abstraction for bit interleaved coded orthogonal frequency division multiplexing(BIC-OFDM) system from a parallel bit channel perspective. By combining the exponential effe...In this paper, we analyze the physical layer abstraction for bit interleaved coded orthogonal frequency division multiplexing(BIC-OFDM) system from a parallel bit channel perspective. By combining the exponential effective SNR(signal-to-noise ratio) mapping(EESM) with the maximum a posteriori(MAP) algorithm, a bit LLR(log-likelihood ratio) wise EESM(BL-EESM) method is proposed. This method can abstract the link performance with high accuracy, especially for the case when channel estimation is imperfect. Afterward, the BL-EESM method is simplified by utilizing the non-linear quantization idea, which can reduce the times of exponential operation by two orders of magnitude at wide system bandwidth, yet shows little loss in accuracy. Our proposal can be applied to both system level simulations to save the time consumption and to practical terminals to facilitate the adaptive modulation and coding(AMC) procedure, bringing about throughput improvement at low hardware cost.展开更多
With the rapid development of computer technology, two-dimensional and three-dimensional technology continues is also attracting attention, computer graphics is more and more widely applied to various fields, especial...With the rapid development of computer technology, two-dimensional and three-dimensional technology continues is also attracting attention, computer graphics is more and more widely applied to various fields, especially with the popularity of decoration, interior design has become the gold industry, computer graphics has played an indispensable role in the interior design, has become an important means of expression of interior design the. Complete the design process: first using the Auto CAD idea sketch design, and then use 3Ds MAX to create the deployment model, import material, build cameras add light, render output, and finally the use of Photoshop post processing. Only through the Photoshop post processing to make the post effect diagram to achieve realistic results. This paper introduces some methods of Photoshop in interior design commonly used in making and adjustment.展开更多
Background:Voxel-based morphometry(VBM)using structural brain MRI has been widely used for the assessment of impairment in Alzheimer’s disease(AD),but previous studies in VBM studies on AD remain inconsistent.Objecti...Background:Voxel-based morphometry(VBM)using structural brain MRI has been widely used for the assessment of impairment in Alzheimer’s disease(AD),but previous studies in VBM studies on AD remain inconsistent.Objective:We conducted meta-analyses to integrate the reported studies to determine the consistent grey matter alterations in AD based on VBM method.Methods:The PubMed,ISI Web of Science,EMBASE and Medline database were searched for articles between 1995 and June 2014.Manual searches were also conducted,and authors of studies were contacted for additional data.Coordinates were extracted from clusters with significant grey matter difference between AD patients and healthy controls(HC).Meta-analysis was performed using a new improved voxel-based meta-analytic method,Effect Size Signed Differential Mapping(ES-SDM).Results:Thirty data-sets comprising 960 subjects with AD and 1195 HC met inclusion criteria.Grey matter volume(GMV)reduction at 334 coordinates in AD and no GMV increase were found in the current meta-analysis.Significant reductions in GMV were robustly localized in the limbic regions(left parahippocampl gyrus and left posterior cingulate gyrus).In addition,there were GM decreases in right fusiform gyrus and right superior frontal gyrus.The findings remain largely unchanged in the jackknife sensitivity analyses.Conclusions:Our meta-analysis clearly identified GMV atrophy in AD.These findings confirm that the most prominent and replicable structural abnormalities in AD are in the limbic regions and contributes to the understanding of pathophysiology underlying AD.展开更多
This study aimed to define the most consistent white matter microarchitecture pattern in Parkinson’s disease(PD)reflected by fractional anisotropy(FA),addressing clinical profiles and methodology-related heterogeneit...This study aimed to define the most consistent white matter microarchitecture pattern in Parkinson’s disease(PD)reflected by fractional anisotropy(FA),addressing clinical profiles and methodology-related heterogeneity.Web-based publication databases were searched to conduct a meta-analysis of whole-brain diffusion tensor imaging studies comparing PD with healthy controls(HC)using the anisotropic effect size–signed differential mapping.A total of 808 patients with PD and 760 HC coming from 27 databases were finally included.Subgroup analyses were conducted considering heterogeneity with respect to medication status,disease stage,analysis methods,and the number of diffusion directions in acquisition.Compared with HC,patients with PD had decreased FA in the left middle cerebellar peduncle,corpus callosum(CC),left inferior fronto-occipital fasciculus,and right inferior longitudinal fasciculus.Most of the main results remained unchanged in subgroup metaanalyses of medicated patients,early stage patients,voxel-based analysis,and acquisition with˂30 diffusion directions.The subgroup meta-analysis of medication-free patients showed FA decrease in the right olfactory cortex.The cerebellum and CC,associated with typical motor impairment,showed the most consistent FA decreases in PD.Medication status,analysis approaches,and the number of diffusion directions have an important impact on the findings,needing careful evaluation in future meta-analyses.展开更多
文摘Objective The purpose of the study was to investigate the effective parameters of electric cortex stimulation (ECS) for functional brain mapping. Methods We collected 21 subjects who underwent epilepsy surgeries consecutively in Beijing Institute of Functional Neurosurgery with the epileptogenic zone located in perirolandic areas from
基金the Shanghai Basic Research KeyProject(No.11DZ1500206)the NationalScience and Technology Major Project of China(No.2012ZX03001013-003)
文摘In this paper, we analyze the physical layer abstraction for bit interleaved coded orthogonal frequency division multiplexing(BIC-OFDM) system from a parallel bit channel perspective. By combining the exponential effective SNR(signal-to-noise ratio) mapping(EESM) with the maximum a posteriori(MAP) algorithm, a bit LLR(log-likelihood ratio) wise EESM(BL-EESM) method is proposed. This method can abstract the link performance with high accuracy, especially for the case when channel estimation is imperfect. Afterward, the BL-EESM method is simplified by utilizing the non-linear quantization idea, which can reduce the times of exponential operation by two orders of magnitude at wide system bandwidth, yet shows little loss in accuracy. Our proposal can be applied to both system level simulations to save the time consumption and to practical terminals to facilitate the adaptive modulation and coding(AMC) procedure, bringing about throughput improvement at low hardware cost.
文摘With the rapid development of computer technology, two-dimensional and three-dimensional technology continues is also attracting attention, computer graphics is more and more widely applied to various fields, especially with the popularity of decoration, interior design has become the gold industry, computer graphics has played an indispensable role in the interior design, has become an important means of expression of interior design the. Complete the design process: first using the Auto CAD idea sketch design, and then use 3Ds MAX to create the deployment model, import material, build cameras add light, render output, and finally the use of Photoshop post processing. Only through the Photoshop post processing to make the post effect diagram to achieve realistic results. This paper introduces some methods of Photoshop in interior design commonly used in making and adjustment.
基金by grants from the National Natural Science Foundation of China(81471309,81371406,81171209)the Natural Science Foundation of Beijing(No.7152096)+3 种基金the Shandong Provincial Outstanding Medical Academic Professional ProgramShandong Provincial Collaborative Innovation Center for Neurodegenerative DisordersQingdao Key Health Discipline Development FundQingdao Outstanding Health Professional Development Fund.
文摘Background:Voxel-based morphometry(VBM)using structural brain MRI has been widely used for the assessment of impairment in Alzheimer’s disease(AD),but previous studies in VBM studies on AD remain inconsistent.Objective:We conducted meta-analyses to integrate the reported studies to determine the consistent grey matter alterations in AD based on VBM method.Methods:The PubMed,ISI Web of Science,EMBASE and Medline database were searched for articles between 1995 and June 2014.Manual searches were also conducted,and authors of studies were contacted for additional data.Coordinates were extracted from clusters with significant grey matter difference between AD patients and healthy controls(HC).Meta-analysis was performed using a new improved voxel-based meta-analytic method,Effect Size Signed Differential Mapping(ES-SDM).Results:Thirty data-sets comprising 960 subjects with AD and 1195 HC met inclusion criteria.Grey matter volume(GMV)reduction at 334 coordinates in AD and no GMV increase were found in the current meta-analysis.Significant reductions in GMV were robustly localized in the limbic regions(left parahippocampl gyrus and left posterior cingulate gyrus).In addition,there were GM decreases in right fusiform gyrus and right superior frontal gyrus.The findings remain largely unchanged in the jackknife sensitivity analyses.Conclusions:Our meta-analysis clearly identified GMV atrophy in AD.These findings confirm that the most prominent and replicable structural abnormalities in AD are in the limbic regions and contributes to the understanding of pathophysiology underlying AD.
基金supported by the National Natural Science Foundation(Nos.81621003,81761128023,81220108013,81227002,and 81030027)the Program for Innovative Research Team in University(No.IRT16R52)of China+1 种基金the Professorship Award(No.T2014190)of Chinathe CMB Distinguished Professorship Award(No.F510000/G16916411)administered by the Institute of International Education.
文摘This study aimed to define the most consistent white matter microarchitecture pattern in Parkinson’s disease(PD)reflected by fractional anisotropy(FA),addressing clinical profiles and methodology-related heterogeneity.Web-based publication databases were searched to conduct a meta-analysis of whole-brain diffusion tensor imaging studies comparing PD with healthy controls(HC)using the anisotropic effect size–signed differential mapping.A total of 808 patients with PD and 760 HC coming from 27 databases were finally included.Subgroup analyses were conducted considering heterogeneity with respect to medication status,disease stage,analysis methods,and the number of diffusion directions in acquisition.Compared with HC,patients with PD had decreased FA in the left middle cerebellar peduncle,corpus callosum(CC),left inferior fronto-occipital fasciculus,and right inferior longitudinal fasciculus.Most of the main results remained unchanged in subgroup metaanalyses of medicated patients,early stage patients,voxel-based analysis,and acquisition with˂30 diffusion directions.The subgroup meta-analysis of medication-free patients showed FA decrease in the right olfactory cortex.The cerebellum and CC,associated with typical motor impairment,showed the most consistent FA decreases in PD.Medication status,analysis approaches,and the number of diffusion directions have an important impact on the findings,needing careful evaluation in future meta-analyses.