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Dynamic Interaction Analysis of Coupled Axial-Torsional-Lateral Mechanical Vibrations in Rotary Drilling Systems
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作者 Sabrina Meddah Sid Ahmed Tadjer +3 位作者 Abdelhakim Idir Kong Fah Tee Mohamed Zinelabidine Doghmane Madjid Kidouche 《Structural Durability & Health Monitoring》 EI 2025年第1期77-103,共27页
Maintaining the integrity and longevity of structures is essential in many industries,such as aerospace,nuclear,and petroleum.To achieve the cost-effectiveness of large-scale systems in petroleum drilling,a strong emp... Maintaining the integrity and longevity of structures is essential in many industries,such as aerospace,nuclear,and petroleum.To achieve the cost-effectiveness of large-scale systems in petroleum drilling,a strong emphasis on structural durability and monitoring is required.This study focuses on the mechanical vibrations that occur in rotary drilling systems,which have a substantial impact on the structural integrity of drilling equipment.The study specifically investigates axial,torsional,and lateral vibrations,which might lead to negative consequences such as bit-bounce,chaotic whirling,and high-frequency stick-slip.These events not only hinder the efficiency of drilling but also lead to exhaustion and harm to the system’s components since they are difficult to be detected and controlled in real time.The study investigates the dynamic interactions of these vibrations,specifically in their high-frequency modes,usingfield data obtained from measurement while drilling.Thefindings have demonstrated the effect of strong coupling between the high-frequency modes of these vibrations on drilling sys-tem performance.The obtained results highlight the importance of considering the interconnected impacts of these vibrations when designing and implementing robust control systems.Therefore,integrating these compo-nents can increase the durability of drill bits and drill strings,as well as improve the ability to monitor and detect damage.Moreover,by exploiting thesefindings,the assessment of structural resilience in rotary drilling systems can be enhanced.Furthermore,the study demonstrates the capacity of structural health monitoring to improve the quality,dependability,and efficiency of rotary drilling systems in the petroleum industry. 展开更多
关键词 Rotary drilling systems mechanical vibrations structural durability dynamic interaction analysis field data analysis
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Mechanical Properties of Copper with Dendritic Silver Inclusions:Insights from Molecular Dynamics Simulations
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作者 Nicolás Amigo 《Computers, Materials & Continua》 SCIE EI 2024年第12期3665-3678,共14页
This study explores the mechanical behavior of single-crystal copper with silver inclusions,focusing on the effects of dendritic and spherical geometries using molecular dynamics simulations.Uniaxial tensile tests rev... This study explores the mechanical behavior of single-crystal copper with silver inclusions,focusing on the effects of dendritic and spherical geometries using molecular dynamics simulations.Uniaxial tensile tests reveal that dendritic inclusions lead to an earlier onset of plasticity due to the presence of high-strain regions at the complex inclusion/matrix interfaces,whereas spherical inclusions exhibit delayed plasticity associated with their symmetric geometry and homogeneous strain distribution.During the plastic regime,the dislocation density is primarily influenced by the volume fraction of silver inclusions rather than their shape,with spherical inclusions showing the highest densities due to their larger volume and higher silver content.Stacking faults,quantified via hexagonal closed-packed atom populations,are strongly correlated with dislocation activity but exhibit transient behavior,indicating that many faults are swept out or transformed during deformation.This transfient effect is observed in all cases,independently of the inclusion size.These findings highlight the complex interplay between inclusion geometry,dislocation activity,and stacking fault evolution in shaping the mechanical properties of copper.The study underscores the need to account for inclusion morphology and defect dynamics when designing advanced copper-based materials and suggests further investigations into the role of dendrite orientation and distribution to enhance material performance in engineering applications. 展开更多
关键词 DENDRITES INCLUSIONS mechanical properties molecular dynamics
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Solvent transport dynamics and its effect on evolution of mechanical properties of nitrocellulose(NC)-based propellants under hot-air drying process
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作者 Enfa Fu Mingjun Yi +1 位作者 Qianling Liu Zhenggang Xiao 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第2期262-270,共9页
Appropriate drying process with optimized controlling of drying parameters plays a vital role in the improvement of the quality and performance of propellant products.However,few research on solvent transport dynamics... Appropriate drying process with optimized controlling of drying parameters plays a vital role in the improvement of the quality and performance of propellant products.However,few research on solvent transport dynamics within NC-based propellants was reported,and its effect on the evolution of mechanical properties was not interpreted yet.This study is conducted to gain a comprehensive understanding of hot-air drying for NC-based propellants and clarify the effect of temperature on solvent transport behavior and further the change of mechanical properties during drying.The drying kinetic curves show the drying time required is decreased but the steady solvent content is increased and the drying rate is obviously increased with the increase of hot-air temperatures,indicating hot-air temperatures have a significant effect on drying kinetics.A modified drying model was established,and results show it is more appropriate to describe solvent transport behavior within NC-based propellants.Moreover,two linear equations were established to exhibit the relationship between solvent content and its effect on the change of tensile properties,and the decrease of residual solvent content causes an obvious increase of tensile strength and tensile modulus of propellant products,indicating its mechanical properties can be partly improved by adjustment of residual solvent content.The outcomes can be used to clarify solvent transport mechanisms and optimize drying process parameters of double-based gun propellants. 展开更多
关键词 Nitrocellulose-based propellants Solvent transport dynamics mechanical properties Drying kinetics Effective solvent diffusion coefficient
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Analysis of mesoscopic mechanical dynamic characteristics of ballast bed with under sleeper pads 被引量:1
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作者 Xiong Yang Liuyang Yu +3 位作者 Xuejun Wang Zhigang Xu Yu Deng Houxu Li 《Railway Engineering Science》 EI 2024年第1期107-123,共17页
The meso-dynamical behaviour of a high-speed rail ballast bed with under sleeper pads(USPs)was studied.The geometrically irregular refined discrete element model of the ballast particles was constructed using 3D scann... The meso-dynamical behaviour of a high-speed rail ballast bed with under sleeper pads(USPs)was studied.The geometrically irregular refined discrete element model of the ballast particles was constructed using 3D scanning techniques,and the 3D dynamic model of the rail-sleeper-ballast bed was constructed using the coupled discrete element method-multiflexible-body dynamics(DEM-MFBD)approach.We analyse the meso-mechanical dynamics of the ballast bed with USPs under dynamic load on a train and verify the correctness of the model in laboratory tests.It is shown that the deformation of the USPs increases the contact area between the sleeper and the ballast particles,and subsequently the number of contacts between them.As the depth of the granular ballast bed increases,the contact area becomes larger,and the contact force between the ballast particles gradually decreases.Under the action of the elastic USPs,the contact forces between ballast particles are reduced and the overall vibration level of the ballast bed can be reduced.The settlement of the granular ballast bed occurs mainly at the shallow position of the sleeper bottom,and the installation of the elastic USPs can be effective in reducing the stress on the ballast particles and the settlement of the ballast bed. 展开更多
关键词 Under sleeper pads Ballast bed Discrete element method Mesoscopic mechanical dynamic characteristics
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A comparative study on kinetics and dynamics of two dump truck lifting mechanisms using MATLAB simscape
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作者 Thong Duc Hong Minh Quang Pham +2 位作者 Son Cong Tran Lam Quang Tran Truong Thanh Nguyen 《Theoretical & Applied Mechanics Letters》 CAS CSCD 2024年第2期146-156,共11页
In this paper,two lifting mechanism models with opposing placements,which use the same hydraulic hoist model and have the same angle of 50°,have been developed.The mechanical and hydraulic simulation models are e... In this paper,two lifting mechanism models with opposing placements,which use the same hydraulic hoist model and have the same angle of 50°,have been developed.The mechanical and hydraulic simulation models are established using MATLAB Simscape to analyze their kinetics and dynamics in the lifting and holding stages.The simulation findings are compared to the analytical calculation results in the steady state,and both methods show good agreement.In the early lifting stage,Model 1 produces greater force and discharges goods in the container faster than Model 2.Meanwhile,Model 2 reaches a higher force and ejects goods from the container cleaner than its counterpart at the end lifting stage.The established simulation models can consider the effects of dynamic loads due to inertial moments and forces generated during the system operation.It is crucial in studying,designing,and optimizing the structure of hydraulic-mechanical systems. 展开更多
关键词 Dump truck Lifting mechanism HYDRAULIC MATLAB Simscape Kinetic dynamic analysis
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Experimental and numerical study on dynamic mechanical behaviors of shale under true triaxial compression at high strain rate
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作者 Xiaoping Zhou Linyuan Han +1 位作者 Jing Bi Yundong Shou 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第2期149-165,共17页
High-energy gas fracturing of shale is a novel,high efficacy and eco-friendly mining technique,which is a typical dynamic perturbing behavior.To effectively extract shale gas,it is important to understand the dynamic ... High-energy gas fracturing of shale is a novel,high efficacy and eco-friendly mining technique,which is a typical dynamic perturbing behavior.To effectively extract shale gas,it is important to understand the dynamic mechanical properties of shale.Dynamic experiments on shale subjected to true triaxial compression at different strain rates are first conducted in this research.The dynamic stress-strain curves,peak strain,peak stress and failure modes of shale are investigated.The results of the study indicate that the intermediate principal stress and the minor principal stress have the significant influence on the dynamic mechanical behaviors,although this effect decreases as the strain rate increases.The characteristics of compression-shear failure primarily occur in shale subjected to triaxial compression at high strain rates,which distinguishes it from the fragmentation characteristics observed in shale under dynamic uniaxial compression.Additionally,a numerical three-dimensional Split Hopkinson Pressure Bar(3D-SHPB),which is established by coupling PFC3D and FLAC3D methods,is validated to replicate the laboratory characteristics of shale.The dynamic mechanical characteristics of shale subjected to different confining stresses are systematically investigated by the coupling PFC3D and FLAC3D method.The numerical results are in good agreement with the experimental data. 展开更多
关键词 dynamic behaviors True triaxial compression High strain rates dynamic failure mechanism PFC3D-FLAC3D coupled method
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Dynamic mechanical characteristics of deep Jinping marble in complex stress environments
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作者 Chendi Lou Heping Xie +6 位作者 Ru Zhang Hai Ren Hao Luo Kun Xiao Yuan Peng Qiang Tan Li Ren 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第2期630-644,共15页
To reveal the dynamic mechanical characteristics of deep rocks,a series of impact tests under triaxial static stress states corresponding to depths of 300-2400 m were conducted.The results showed that both the strain ... To reveal the dynamic mechanical characteristics of deep rocks,a series of impact tests under triaxial static stress states corresponding to depths of 300-2400 m were conducted.The results showed that both the strain rates and the stress environments in depth significantly affect the mechanical characteristics of rocks.The sensitivity of strain rate to the dynamic strength and deformation modulus shows a negative correlation with depth,indicating that producing penetrative cracks in deep environments is more difficult when damage occurs.The dynamic strength shows a tendency to decrease and then increase slightly,but decreases sharply finally.Transmissivity demonstrates a similar trend as that of strength,whereas reflectivity indicates the opposite trend.Furthermore,two critical depths with high dynamically induced hazard possibilities based on the China Jinping Underground Laboratory(CJPL)were proposed for deep engineering.The first critical depth is 600-900 m,beyond which the sensitivity of rock dynamic characteristics to the strain rate and restraint of circumferential stress decrease,causing instability of surrounding rocks under axial stress condition.The second one lies at 1500-1800 m,where the wave impedance and dynamic strength of deep surrounding rocks drop sharply,and the dissipation energy presents a negative value.It suggests that the dynamic instability of deep surrounding rocks can be divided into dynamic load dominant and dynamic load induced types,depending on the second critical depth. 展开更多
关键词 Rock mechanics Split-Hopkinson pressure bar Coupled static‒dynamic loading Different depths Holmquist-Johnson-Cook(HJC)model
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Experimental study and numerical simulation of the impact of under-sleeper pads on the dynamic and static mechanical behavior of heavy-haul railway ballast track
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作者 Yihao Chi Hong Xiao +2 位作者 Yang Wang Zhihai Zhang Mahantesh M.Nadakatti 《Railway Engineering Science》 EI 2024年第3期384-400,共17页
Laying the under-sleeper pad(USP)is one of the effective measures commonly used to delay ballast degradation and reduce maintenance workload.To explore the impact of application of the USP on the dynamic and static me... Laying the under-sleeper pad(USP)is one of the effective measures commonly used to delay ballast degradation and reduce maintenance workload.To explore the impact of application of the USP on the dynamic and static mechanical behavior of the ballast track in the heavy-haul railway system,numerical simulation models of the ballast bed with USP and without USP are presented in this paper by using the discrete element method(DEM)-multi-flexible body dynamic(MFBD)coupling analysis method.The ballast bed support stiffness test and dynamic displacement tests were carried out on the actual operation of a heavy-haul railway line to verify the validity of the models.The results show that using the USP results in a 43.01%reduction in the ballast bed support stiffness and achieves a more uniform distribution of track loads on the sleepers.It effectively reduces the load borne by the sleeper directly under the wheel load,with a 7.89%reduction in the pressure on the sleeper.Furthermore,the laying of the USP changes the lateral resistance sharing ratio of the ballast bed,significantly reducing the stress level of the ballast bed under train loads,with an average stress reduction of 42.19 kPa.It also reduces the plastic displacement of ballast particles and lowers the peak value of rotational angular velocity by about 50%to 70%,which is conducive to slowing down ballast bed settlement deformation and reducing maintenance costs.In summary,laying the USP has a potential value in enhancing the stability and extending the lifespan of the ballast bed in heavy-haul railway systems. 展开更多
关键词 Heavy-haul railway Under-sleeper pad Discrete element method Multi-flexible body dynamic coupling analysis mechanical behavior Quality state
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Refinement of Adaptive Dynamical Simulation of Quantum Mechanical Double Slit Interference Phenomenon
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作者 Tadashi Ando Andrei Khrennikov Ichiro Yamato 《Journal of Modern Physics》 2024年第3期239-249,共11页
We applied adaptive dynamics to double slit interference phenomenon using particle model and obtained partial successful results in our previous report. The patterns qualitatively corresponded well with experiments. S... We applied adaptive dynamics to double slit interference phenomenon using particle model and obtained partial successful results in our previous report. The patterns qualitatively corresponded well with experiments. Several properties such as concave single slit pattern and large influence of slight displacement of the emission position were different from the experimental results. In this study we tried other slit conditions and obtained consistent patterns with experiments. We do not claim that the adaptive dynamics is the principle of quantum mechanics, but the present results support the probability of adaptive dynamics as the candidate of the basis of quantum mechanics. We discuss the advantages of the adaptive dynamical view for foundations of quantum mechanics. 展开更多
关键词 Double Slit Interference Adaptive dynamics Quantum mechanics Particle Model Simulation
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A Computational Fluid Dynamics (CFD) Analysis of an Undulatory Mechanical Fin Driven by Shape Memory Alloy 被引量:8
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作者 Yong-Hua Zhang Jian-Hui He +2 位作者 Jie Yang Shi-Wu Zhang Kin Huat Low 《International Journal of Automation and computing》 EI 2006年第4期374-381,共8页
Many fishes use undulatory fin to propel themselves in the underwater environment. These locomotor mechanisms have a popular interest to many researchers. In the present study, we perform a three-dimensional unsteady ... Many fishes use undulatory fin to propel themselves in the underwater environment. These locomotor mechanisms have a popular interest to many researchers. In the present study, we perform a three-dimensional unsteady computation of an undulatory mechanical fin that is driven by Shape Memory Alloy (SMA). The objective of the computation is to investigate the fluid dynamics of force production associated with the undulatory mechanical fin. An unstructured, grid-based, unsteady Navier-Stokes solver with automatic adaptive remeshing is used to compute the unsteady flow around the fin through five complete cycles. The pressure distribution on fin surface is computed and integrated to provide fin forces which are decomposed into lift and thrust. The velocity field is also computed throughout the swimming cycle. Finally, a comparison is conducted to reveal the dynamics of force generation according to the kinematic parameters of the undulatory fin (amplitude, frequency and wavelength). 展开更多
关键词 Computational Fluid dynamics (CFD) undulatory mechanical fin unsteady flow unstructured mesh Shape Memory Alloy (SMA)
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Molecular dynamics simulation of nanometer scale mechanical properties of hexagonal Mgsingle bondLi alloy 被引量:4
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作者 Avik Mahata Koushik Sikdar 《Journal of Magnesium and Alloys》 SCIE EI CAS 2016年第1期36-43,共8页
Nano mechanical behavior of Mgsingle bondLi nanowire is investigated under tension and compression to elicit property alteration due to Li alloying in Mg within hexagonal range.Embedded atom method(EAM)is employed to ... Nano mechanical behavior of Mgsingle bondLi nanowire is investigated under tension and compression to elicit property alteration due to Li alloying in Mg within hexagonal range.Embedded atom method(EAM)is employed to carry out present simulation work.Nanowire under consideration is supposed to be isotropic and mechanical behavior is uninfluenced by material texture.The elastic modulus,yield strength both in tension and compression is assessed with change in strain rate.Effects of temperature in tension and compression are studied.Results of present simulation work elicit serrated yielding under uniaxial tension,however,twin mediated deformation under compression is completely tuned with previously reported experimental works.This investigation bridges nanometer scale properties to microscale material response,which in turn can be applied for designing suitable robust processing routes of this material. 展开更多
关键词 Molecular dynamic simulation NANOWIRE mechanical behavior
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MECHANICAL BEHAVIOR OF FCC CRYSTAL SIMULATED BY 3-D DISCRETE DISLOCATION DYNAMICS 被引量:1
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作者 Y.Yu X.X. Pan Y.H. Rong 《Acta Metallurgica Sinica(English Letters)》 SCIE EI CAS CSCD 2008年第2期94-102,共9页
To simulate the mechanical behavior of the FCC crystal with the lower Peierls stress, the stiff property and physical meaning of the differential equation group consisting of dislocation evolution and mechanical state... To simulate the mechanical behavior of the FCC crystal with the lower Peierls stress, the stiff property and physical meaning of the differential equation group consisting of dislocation evolution and mechanical state was investigated based on the 3-D discrete dislocation dynamics; the results indicate that the differential equation group is serious stiff, namely the external stress changes more quickly than dislocation evolution. Using the established numerical algorithm, the mechanical behavior of FCC crystal was simulated with the dislocations located in the parallel slip planes, and the effect of strain rate on the dislocation configuration and mechanical behavior, and the sat- uration process of mobile dislocation were discussed. The simulation results indicate that the numerical algorithm can efficiently simulate the dislocation dipole and the low strain rate loading. 展开更多
关键词 FCC crystal mechanical behavior Dislocation dynamics Nu-merical simulation
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NONLINEAR DYNAMICS MODFLING OF MECHANICAL PERIODICITY OF END DIASTOLIC VOLUME OF LEFT VENTRICLE 被引量:1
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作者 XU Shi-xiong(许世雄) +1 位作者 MAO Xiao-chun(毛晓春) 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2001年第10期1183-1191,共9页
The cardiovascular system with a lumped parameter model is treated, in which the Starling model is used to simulate left ventricle and the four-element Burattini & Gnudi model is used in the description of... The cardiovascular system with a lumped parameter model is treated, in which the Starling model is used to simulate left ventricle and the four-element Burattini & Gnudi model is used in the description of arterial system. Moreover, the feedback action of arterial pressure on cardiac cycle is taken into account. The phenomenon of mechanical periodicity (MP) of end diastolic volume (EDV) of left ventricle is successfully simulated by solving a series of one-dimensional discrete nonlinear dynamical equations. The effects of cardiovascular parameters on MP is also discussed. 展开更多
关键词 left ventricle end diastolic volume mechanical periodicity nonlinear dynamics
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Mechanical property and deformation mechanism of gold nanowire with non-uniform distribution of twinned boundaries:A molecular dynamics simulation study 被引量:2
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作者 Qi-Xin Xiao Zhao-Yang Hou +1 位作者 Chang Li Yuan Niu 《Chinese Physics B》 SCIE EI CAS CSCD 2021年第5期520-525,共6页
The mechanical property and deformation mechanism of twinned gold nanowire with non-uniform distribution of twinned boundaries(TBs)are studied by the molecular dynamics(MD)method.It is found that the twin boundary spa... The mechanical property and deformation mechanism of twinned gold nanowire with non-uniform distribution of twinned boundaries(TBs)are studied by the molecular dynamics(MD)method.It is found that the twin boundary spacing(TBS)has a great effect on the strength and plasticity of the nanowires with uniform distribution of TBs.And the strength enhances with the decrease of TBS,while its plasticity declines.For the nanowires with non-uniform distribution of TBs,the differences in distribution among different TBSs have little effect on the Young's modulus or strength,and the compromise in strength appears.But the differences have a remarkable effect on the plasticity of twinned gold nanowire.The twinned gold nanowire with higher local symmetry ratio has better plasticity.The initial dislocations always form in the largest TBS and the fracture always appears at or near the twin boundaries adjacent to the smallest TBS.Some simulation results are consistent with the experimental results. 展开更多
关键词 twin nanowire GOLD non-uniform distribution mechanical property molecular dynamics simulation
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Investigation of mechanical properties of twin gold crystal nanowires under uniaxial load by molecular dynamics method 被引量:1
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作者 张国伟 杨在林 罗刚 《Chinese Physics B》 SCIE EI CAS CSCD 2016年第8期279-283,共5页
Twin gold crystal nanowires, whose loading direction is parallel to the twin boundary orientation, are simulated.We calculate the nanowires under tensile or compressive loads, different length nanowires, and different... Twin gold crystal nanowires, whose loading direction is parallel to the twin boundary orientation, are simulated.We calculate the nanowires under tensile or compressive loads, different length nanowires, and different twin boundary nanowires respectively. The Young modulus of nanowires under compressive load is about twice that under tensile load.The compressive properties of twin gold nanowires are superior to their tensile properties. For different length nanowires,there is a critical value of length with respect to the mechanical properties. When the length of nanowire is greater than the critical value, its mechanical properties are sensitive to length. The twin boundary spacing hardly affects the mechanical properties. 展开更多
关键词 molecular dynamics twinned crystal boundary gold nanowires uniaxial load mechanical prop-erties
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Investigation on the Mechanical Properties of Polycrystalline Mg Using Molecular Dynamics Simulation 被引量:1
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作者 Xiaoxia Liu 《Computer Modeling in Engineering & Sciences》 SCIE EI 2022年第5期919-927,共9页
Magnesium(Mg)and its composites have been widely used in different fields,but the mechanical properties and deformation mechanisms of polycrystalline Mg(polyMg)at the atomic scale are poorly understood.In this paper,t... Magnesium(Mg)and its composites have been widely used in different fields,but the mechanical properties and deformation mechanisms of polycrystalline Mg(polyMg)at the atomic scale are poorly understood.In this paper,the effects of grain size,temperature,and strain rate on the tensile properties of polyMg are explored and discussed by theMolecular dynamics(MD)simulation method.The calculated results showed that there exists a critical grain size of 10 nm for the mechanical properties of polyMg.The flow stress decreases with the increase of grain size if the average grain size is larger than 10 nm,which shows the Hall-Petch effect,and the deformation mechanism of large grain-sized polyMg is mainly dominated by the movement of dislocations.When the average grain size is less than 10 nm,it shows the reverse Hall-Petch effect that the flow stress decreases with the decrease of grain size,and the deformation mode of polyMg with small grain-size is the movement and deformation of atoms at the grain boundary.Due to the more active motion of atoms as the system temperature increases,the material can easily reach the plastic stage under tensile loading,and the mechanical properties of polyMg decrease at high temperatures.The strain rate has a hardening effect on the properties of composite.Based on our calculated results,it can provide theoretical guidance for the applications of Mg metal and Mg matrix composites. 展开更多
关键词 Polycrystalline magnesium molecular dynamics simulation TEMPERATURE strain rate mechanical properties
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Structure and Mechanical Behavior of Cellulose Nanofiber and Micro-Fibrils by Molecular Dynamics Simulation 被引量:1
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作者 Ken-ichi Saitoh Haruhiko Ohno Syunichiro Matsuo 《Soft Nanoscience Letters》 2013年第3期58-67,共10页
Cellulose nanofiber (CNF) and CNF micro-fibrils (CNF-MFs) are computationally modeled by molecular dynamics with united atom (UA) methodology of polymers. Structural stability and mechanical properties of these materi... Cellulose nanofiber (CNF) and CNF micro-fibrils (CNF-MFs) are computationally modeled by molecular dynamics with united atom (UA) methodology of polymers. Structural stability and mechanical properties of these materials are focused on. Diffusion coefficient decreases with increase of the number of shells in CNF-MF. The structure of CNF-MFs with crystalline alignment is totally stabilized with twist which is an accumulation of torsion angles at Glycosidic bonds between monomers inside CNFs. Unique fiber drawing simulation, where a single CNF fiber is taken out of CNF-MF structure, is first conducted. The CNF fiber which is drawn out stretches up to relatively large strain, with linear increase of tensile stress. The computation results show that, the larger the number of shell structure of CNF-MF is, the larger the stretch and the stress of drawn fibers are. 展开更多
关键词 CELLULOSE NANOFIBER Molecular dynamics WIREDRAWING mechanical Properties Biomaterial TWIST Angle
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Ultrasound Tweezers Trigger Single-Cell Mechanical Dynamics for Cell Mechanophenotyping
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作者 Weiyi Qian Apratim Bajpai +2 位作者 Jie Tong Zijing Zhang Weiqiang Chen 《医用生物力学》 EI CAS CSCD 北大核心 2019年第A01期46-46,共1页
Cells actively modulate mechanobiological circuitry against external perturbations to stabilize whole cell/tissue physiology.The dynamic adaption of cells to mechanical force is critical for cells to perform vital bio... Cells actively modulate mechanobiological circuitry against external perturbations to stabilize whole cell/tissue physiology.The dynamic adaption of cells to mechanical force is critical for cells to perform vital biological functions,from single cell migration to embryonic development.Dysregulation of such dynamics has been associated with pathophysiological conditions in cardiovascular diseases,cancer,aging,and developmental disorders[1].Therefore,a direct understanding of cell’s biomechanical adaptive/maladaptive behaviors and the trigger factors causing the transformation of healthy adaption to maladaptation can help reveal the regulatory role of single cell mechanosensitive dynamics in the progression of various degenerative diseases and aging.However,current efforts for uncovering fundamental associations between disease and cell architecture have been focusing on'static'measurements of biophysical properties,which is limited by the requirement of large sample sizes to obtain statistically significant data.We therefore developed a single and highly integrated platform with mechanical stimulation and fine spatiotemporal sensing functions to probe the single cell mechanical dynamics at subcellular level to determine cell’s mechanophenotypes in healthy and disease conditions.We developed an integrated micromechanical system composed of an’ultrasound tweezer’stimulator[2]and a PDMS micropillar array [3] cellular force sensor to in situ noninvasively probe and monitor single cell mechanical dynamics.Vascular smooth muscle cells(VSMCs)from healthy mouse and mouse with induced abdominal aorta aneurysm(AAA)were used for cell mechanobiological study.An ultrasound transducer(V312-SM,Olympus)was used to generate ultrasound pulses to excite lipid-encapsulated microbubbles(Targeson)binding to cell membrane through an RGD-integrin linkage to apply a transient nanonewton force to VSMCs seeded on the PDMS micropillar array.PDMS micropillar array was fabricated and functionalized as previously described [3] and acts as the mechanical force sensor in our platform.Upon a 1 HZ and 10-second ultrasound stimulation,calcium influx was clearly detected in both healthy and AAA-VSMCs by using the fluo-4 calcium sensor,suggesting the microbubble-integrin-actin cytoskeleton(CSK)linkage can serve as a mechanosensory to sense the ultrasound stimulation.We then examined how healthy and AAA VSMCs would exhibit adaptions to mechanical stimulation at a global cellular scale.After the onset of a 10-second ultrasound stimulation,control and AAA-VSMCs displayed distinct dynamics of CSK tension within 30 mins,in which the CSK tension of healthy VSMCs increased within the reinforcement period(0-5 min)and restored to their ground state with the relaxation period(5-10 min);yet AAA-VSMCs displayed compromised dynamics of such CSK tension upon calcium influx.Quantitative analysis and theoretical modelling revealed the critical roles of myosin motor contraction,F-actin filament polymerization in regulating cell mechanosensitive dynamics in response to a transient mechanical perturbation.The distinct force and CSK dynamics in healthy and AAA conditions indicates that the force-dependent CSK molecular kinetics is a critical factor governing the distinct mechanosensitive dynamics of cells under pathologically dysfunctional conditions.Our results reveal that the mechanical adaptive process of cells to mechanical stimulus can measure the cellular mechanobiological phenotypes featured in both pathologically healthy and diseased context.We demonstrated that an altered mechanobiological phenotype,i.e.AAA-VSMCs with distinct actomyosin-CSK properties potentiates a mechanical maladaptation that reflects progressive accumulation of cellular damage and dysfunction.This may further reveal the pathogenic contexts and their physical mediators featuring biophysical dysregulation in cardiovascular diseases. 展开更多
关键词 AAA ULTRASOUND TWEEZERS TRIGGER SINGLE-CELL mechanical dynamics CELL mechanophenotyping
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Molecular dynamics simulations of mechanical properties of epoxy-amine:Cross-linker type and degree of conversion effects
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作者 Yongqin Zhang Hua Yang +2 位作者 Yaguang Sun Xiangrui Zheng Yafang Guo 《Chinese Physics B》 SCIE EI CAS CSCD 2022年第6期396-402,共7页
Molecular dynamics(MD)simulations are conducted to study the thermo-mechanical properties of a family of thermosetting epoxy-amines.The crosslinked epoxy resin EPON862 with a series of cross-linkers is built and simul... Molecular dynamics(MD)simulations are conducted to study the thermo-mechanical properties of a family of thermosetting epoxy-amines.The crosslinked epoxy resin EPON862 with a series of cross-linkers is built and simulated under the polymer consistent force field(PCFF).Three types of curing agents(rigidity1,3-phenylenediamine(1,3-P),4,4-diaminodiphenylmethane(DDM),and phenol-formaldehyde-ethylenediamine(PFE))with different numbers of active sites are selected in the simulations.We focus on the effects of the cross-linkers on thermo-mechanical properties such as density,glass transition temperature(T_(g)),elastic constants,and strength.Our simulations show a significant increase in the Tg,Young’s modulus and yield stress with the increase in the degree of conversion.The simulation results reveal that the mechanical properties of thermosetting polymers are strongly dependent on the molecular structures of the cross-linker and network topological properties,such as end-to-end distance,crosslinking density and degree of conversion. 展开更多
关键词 POLYMER molecular dynamic simulation mechanical properties THERMOdynamics
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Mechanical properties and thermal conductivity of pristine and functionalized carbon nanotube reinforced metallic glass composites:A molecular dynamics approach
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作者 Sumit Sharma S.K.Tiwari Sagar Shakya 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2021年第1期234-244,共11页
This work uses the molecular dynamics approach to study the effects of functionalization of carbon nanotubes(CNTs)on the mechanical properties of Cu64Zr36 metallic glass(MG).Three types of functional groups,carboxylic... This work uses the molecular dynamics approach to study the effects of functionalization of carbon nanotubes(CNTs)on the mechanical properties of Cu64Zr36 metallic glass(MG).Three types of functional groups,carboxylic,vinyl and ester were used.The effect of CNT volume fraction(Vf)and the number of functional groups attached to CNT,on the mechanical properties and thermal conductivity of CNT-MG composites was analysed using Biovia Materials Studio.At lower values of Vf(from 0 to 5%),the percentage increase in Young’s modulus was approximately 66%.As the value of Vf was increased further(from 5 to 12%),the rate of increase in Young’s modulus was reduced to 16%.The thermal conductivity was found to increase from 1.52 W/mK at Vf?0%to 5.88 W/mK at Vf?12%,thus giving an increase of approximately 286%.Functionalization of SWCNT reduced the thermal conductivity of the SWCNT-MG composites. 展开更多
关键词 Molecular dynamics Carbon nanotube Metallic glass mechanical properties Thermal conductivity
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