Marine science technology innovation provides power and guarantees for marine eco-civilization construction,which provides direction and material support for marine science technology innovation.Therefore,the coordina...Marine science technology innovation provides power and guarantees for marine eco-civilization construction,which provides direction and material support for marine science technology innovation.Therefore,the coordinated development of the two is of great significance to the marine economy sustainable development in China’s coastal areas.On the basis of clarifying the connotations of marine science technology innovation and marine eco-civilization in China’s coastal areas from 2006 to 2019,the mechanism for their coordinated development was analysed.A comprehensive indicator system based on the connotation of the two was constructed,and the coordinated development relationship was empirically tested using the coupled coordination model and the panel vector autoregressive(PVAR)model.The results show that:1)the level of China’s coastal marine science technology innovation continues to improve,gradually forming the core of the development of marine science technology innovation in the north,east and south of Shandong,Shanghai and Guangdong;the level of marine eco-civilization development fluctuating upward trend,showing obvious spatial differentiation characteristics.2)The degree of coordination of marine science technology innovation and marine eco-civilization is growing over time.There is no causal relationship between marine science technology innovation and marine eco-civilization in the northern marine economic circle,but there is a two-way causal relationship between the two in the eastern and southern marine economic circles.3)Marine eco-civilization shows a significant positive and continuous impact on marine science technology innovation,and marine science technology innovation shows a long-term,continuous,fluctuating,and lagging impact on marine eco-civilization.The overall role of marine eco-civilization on marine science technology innovation is dominant,and there are significant differences in the impact effects of the two major marine economic circles.展开更多
With the implementation of China’s innovation-driven development strategy,the competition among sci-tech talents has become increasingly fierce.Stimulating the innovative vigor of sci-tech talents has become a hot to...With the implementation of China’s innovation-driven development strategy,the competition among sci-tech talents has become increasingly fierce.Stimulating the innovative vigor of sci-tech talents has become a hot topic in theoretical research and policy practice.Based on the data from 246 questionnaires collected from sci-tech talents in Hebei province,this study explored the influence mechanism of an inclusive organizational climate on innovation input from technological talents and verified the mediating effects of innovation self-efficacy and intrinsic motivation.The results indicate that an inclusive organizational climate has a significant positive impact on innovation input,innovation self-efficacy,and intrinsic motivation of sci-tech talents.Both innovation self-efficacy and intrinsic motivation play a partial mediating role between an inclusive climate and innovation input.This study verified the important role of an inclusive climate in an organization’s human resource management practices and encouraged managers to emphasize enhancing the innovation self-efficacy and intrinsic motivation of sci-tech talents,thereby continuously improving the level of innovation.展开更多
The Pudong New Area has followed the standardization polices of the country,vigorously implemented the standardization strategies,and fulfilled the historical mission of“serving as a pioneer of reform&opening-up ...The Pudong New Area has followed the standardization polices of the country,vigorously implemented the standardization strategies,and fulfilled the historical mission of“serving as a pioneer of reform&opening-up and innovative development”.展开更多
Against the backdrop of rapid global economic development,the demand for education has gradually shifted from quantitative growth to qualitative improvement.Vocational education,higher education,and continuing educati...Against the backdrop of rapid global economic development,the demand for education has gradually shifted from quantitative growth to qualitative improvement.Vocational education,higher education,and continuing education are crucial components of China’s education system,each serving different educational functions.However,the collaborative innovation among these three types of education is still in the preliminary exploration stage,with issues such as scattered resources and imperfect coordination mechanisms.This paper systematically reviews relevant domestic and international research and practical experiences,thoroughly analyzes the pathways,models,and mechanisms of collaborative innovation among these three types of education,and proposes practical and operational suggestions based on the actual situation in Xuzhou City.The study finds that collaboration between vocational education,higher education,and continuing education through innovation not only enhances the overall efficiency of educational resources but also promotes regional economic development and social progress.On this basis,this paper proposes specific measures such as building an education resource-sharing platform,promoting a chain-based talent training system,strengthening policy and institutional guarantees,and improving incentive mechanisms,aiming to provide a reference for local education administrators and contribute to the innovative development of education in China.展开更多
Cells,tissues,and organs are constantly subjected to the action of mechanical forces from the extracellular environment-and the nervous system is no exception.Cell-intrinsic properties such as membrane lipid compositi...Cells,tissues,and organs are constantly subjected to the action of mechanical forces from the extracellular environment-and the nervous system is no exception.Cell-intrinsic properties such as membrane lipid composition,abundance of mechanosensors,and cytoskeletal dynamics make cells more or less likely to sense these forces.Intrinsic and extrinsic cues are integrated by cells and this combined information determines the rate and dynamics of membrane protrusion growth or retraction(Yamada and Sixt,2019).Cell protrusions are extensions of the plasma membrane that play crucial roles in diverse contexts such as cell migration and neuronal synapse formation.In the nervous system,neurons are highly dynamic cells that can change the size and number of their pre-and postsynaptic elements(called synaptic boutons and dendritic spines,respectively),in response to changes in the levels of synaptic activity through a process called plasticity.Synaptic plasticity is a hallmark of the nervous system and is present throughout our lives,being required for functions like memory formation or the learning of new motor skills(Minegishi et al.,2023;Pillai and Franze,2024).展开更多
Under the wave of global technological revolution,the new materials industry is facing difficulties in innovation and transformation.Equity investment has become a key driving force due to its flexible mechanism,risk ...Under the wave of global technological revolution,the new materials industry is facing difficulties in innovation and transformation.Equity investment has become a key driving force due to its flexible mechanism,risk sharing,and deep participation.Based on introducing the current development status of China’s new materials industry,this article reveals the mechanism of equity investment in financial support,risk management,incentive constraints,and resource integration.The article proposes optimization strategies,such as building an information-sharing mechanism and a diversified investment fund system,to promote the high-quality development of the new materials industry driven by innovation and provide strategic guidance for policymakers,investors,and enterprises.展开更多
The complex morphological,anatomical,physiological,and chemical mechanisms within the aging brain have been the hot topic of research for centuries.The aging process alters the brain structure that affects functions a...The complex morphological,anatomical,physiological,and chemical mechanisms within the aging brain have been the hot topic of research for centuries.The aging process alters the brain structure that affects functions and cognitions,but the worsening of such processes contributes to the pathogenesis of neurodegenerative disorders,such as Alzheimer's disease.Beyond these observable,mild morphological shifts,significant functional modifications in neurotransmission and neuronal activity critically influence the aging brain.Understanding these changes is important for maintaining cognitive health,especially given the increasing prevalence of age-related conditions that affect cognition.This review aims to explore the age-induced changes in brain plasticity and molecular processes,differentiating normal aging from the pathogenesis of Alzheimer's disease,thereby providing insights into predicting the risk of dementia,particularly Alzheimer's disease.展开更多
Regulated cell death is a form of cell death that is actively controlled by biomolecules.Several studies have shown that regulated cell death plays a key role after spinal cord injury.Pyroptosis and ferroptosis are ne...Regulated cell death is a form of cell death that is actively controlled by biomolecules.Several studies have shown that regulated cell death plays a key role after spinal cord injury.Pyroptosis and ferroptosis are newly discovered types of regulated cell deaths that have been shown to exacerbate inflammation and lead to cell death in damaged spinal cords.Autophagy,a complex form of cell death that is interconnected with various regulated cell death mechanisms,has garnered significant attention in the study of spinal cord injury.This injury triggers not only cell death but also cellular survival responses.Multiple signaling pathways play pivotal roles in influencing the processes of both deterioration and repair in spinal cord injury by regulating pyroptosis,ferroptosis,and autophagy.Therefore,this review aims to comprehensively examine the mechanisms underlying regulated cell deaths,the signaling pathways that modulate these mechanisms,and the potential therapeutic targets for spinal cord injury.Our analysis suggests that targeting the common regulatory signaling pathways of different regulated cell deaths could be a promising strategy to promote cell survival and enhance the repair of spinal cord injury.Moreover,a holistic approach that incorporates multiple regulated cell deaths and their regulatory pathways presents a promising multi-target therapeutic strategy for the management of spinal cord injury.展开更多
In order to improve the cigarette enterprise technology innovation and patent management status, the macro work should start from the four aspects of patent ideology introduction, patent organization design, perfectin...In order to improve the cigarette enterprise technology innovation and patent management status, the macro work should start from the four aspects of patent ideology introduction, patent organization design, perfecting patent system and implementation of specific measures, and attention should be attached to strengthen the cooperation of the cigarette enterprise management departments. On the other hand, Jn the microscopic work level, it should build the culture atmosphere of the entire tobacco industry respect intellectual property rights, actively cultivate the na- tional patent agents and patent engineers, and gradually promote the patent work to develop in the direction of specialization, self-independence, so as to construct a scientific mechanism for patent management, and enhance the core competitiveness of the tobacco industry.展开更多
The rationality and scientific nature of the emission trading mechanism is the key to the effective implementation of environmental and economic policies.As far as China is concerned,there are phenomena such as inform...The rationality and scientific nature of the emission trading mechanism is the key to the effective implementation of environmental and economic policies.As far as China is concerned,there are phenomena such as information asymmetry,low supervision efficiency,and alienation of government and enterprise behaviors caused by the incomplete mechanism of emission trading in the practice of different pilots.The introduction of blockchain technology can innovate the traditional transaction model and form a decentralized peer-to-peer transaction and a trusted emission trading market.To this end,based on the current emission trading mechanism and the characteristics of blockchain technology,this paper couples the core technologies of blockchain with the functional requirements of application scenarios.Then,an innovative application framework is built based on the consortium blockchain Fabric from three aspects:emission trading supervision,secondary trading market construction,as well as emission trading incentive and punishment mechanisms.Technologies such as the consensus mechanism,smart contract,Merkle tree and asymmetric encryption are comprehensively applied in this process.In the construction of the blockchain framework of the secondary market for emission trading,institutional changes and innovations brought about by the blockchain at various levels are analyzed in terms of participants,transaction processes and the transaction scope.At the same time,smart contract functions and algorithms are designed for the purchase,transfer-out and trading of emission rights,and the operation business logic of the smart contract is analyzed.On the whole,this paper explores the application framework of blockchain technology in the field of emission trading at the macro level,and analyzes the application mechanism of the corresponding technologies of blockchain at each coupling point in the framework at the micro level.The collaborative analysis at the two levels shows that blockchain technology and the requirements of emission trading mechanism can be effectively coupled,and the application of blockchain technology can promote the effective supervision of enterprises'emission behavior,making the processes of the purchase,transfer and transaction of emission rights intelligent and automated,and providing technical support for cross regional emission trading to reduce transaction costs and management complexity.In addition,the issuance of emission credits based on smart contract will be a new incentive for companies to actively participate in transactions.Based on the above analysis,this paper believes that the innovative application of blockchain technology is of great significance in the promotion of the market-based allocation of element of emission trading and the rational allocation of environmental resources.It will lead to a major breakthrough in the traditional trading system in terms of trading modes,forming a value transmission network of environmental resources between the government and polluters.展开更多
In the current process of deepening reform in China,industrial structure upgrading,economic structural transformation and new urbanization are important tasks to promote social and economic development,and technologic...In the current process of deepening reform in China,industrial structure upgrading,economic structural transformation and new urbanization are important tasks to promote social and economic development,and technological innovation has gradually become the primary driving force for industrial upgrading,economic transformation and the realization of new urbanization.The article analyzed the action mechanism of scientific and technological innovation on the integration of industrialization and urbanization through qualitative and quantitative methods,found out the prominent problems faced by Henan through the empirical analysis of relevant data of Henan Province,and then proposed the integrated development path driven by scientific and technological innovation.展开更多
Based on the review of related concepts,the current situation and problems of talent training in marine cultural industry in China were analyzed,and talent training mechanisms of marine cultural industry based on coll...Based on the review of related concepts,the current situation and problems of talent training in marine cultural industry in China were analyzed,and talent training mechanisms of marine cultural industry based on collaborative innovation of governments,enterprises,colleges,scientific institutions and users were proposed to promote the transformation,upgrading and vigorous development of marine cultural industry,accelerate the spread of marine culture with Chinese characteristics,and build China into a maritime power.展开更多
E-commerce is a new business model based on Internet information technology,and its internal operation mechanism can be studied in depth from the perspective of the knowledge ecosystem according to the law of knowledg...E-commerce is a new business model based on Internet information technology,and its internal operation mechanism can be studied in depth from the perspective of the knowledge ecosystem according to the law of knowledge ecology.The various knowledge elements in the e-business knowledge ecosystem interact and influence each other,continue to exchange materials and energy according to specific rules,and develop and circulate autonomously so that users can acquire,transfer,share and sublimate knowledge in the business system.Finally,knowledge innovation and new value creation are realized to complete the final value sublimation.Based on this,this paper elaborates on three aspects of e-business ecosystem system synergy theory,e-business ecosystem,and e-business ecosystem synergy and innovation model for the reference of relevant personnel.展开更多
In this paper, we conduct research on the big data and the artificial intelligence aided decision-making mechanism with the applications on video website homemade program innovation. Make homemade video shows new medi...In this paper, we conduct research on the big data and the artificial intelligence aided decision-making mechanism with the applications on video website homemade program innovation. Make homemade video shows new media platform site content production with new possible, as also make the traditional media found in Internet age, the breakthrough point of the times. Site homemade video program, which is beneficial to reduce copyright purchase demand, reduce the cost, avoid the homogeneity competition, rich advertising marketing at the same time, improve the profit pattern, the organic combination of content production and operation, complete the strategic transformation. On the basis of these advantages, once the site of homemade video program to form a brand and a higher brand influence. Our later research provides the literature survey for the related issues.展开更多
The connotation of rural public goods is expounded.The rural public goods refer to the products and labors that satisfy the production and living of rural residents,economic growth and social progress.The rural public...The connotation of rural public goods is expounded.The rural public goods refer to the products and labors that satisfy the production and living of rural residents,economic growth and social progress.The rural public goods is characterized by non-excludability,non-competitiveness and indispensability of other general public goods.The supply situation of Chinese government to rural public goods is analyzed,as well as the demand situation of rural public goods,which includes farmers' demand on training,the assistance demand of rural weak groups,farmers' demand on comfortable living conditions and farmers' demand on "soft" public goods.The paths for innovating the supply mechanism of rural public goods are put forward,which cover perfecting the decision mechanism of public goods supply;scientifically distributing the supply responsibility of rural public goods;facilitating the reform of each supporting equipment and exploring the multiple capital collecting channels of rural public goods.展开更多
The paper summarizes domestic and overseas research results on synergetic innovation. Then it discusses the mechanism of synergetic innovation on industrial clusters according to these theoretical results. Firstly, we...The paper summarizes domestic and overseas research results on synergetic innovation. Then it discusses the mechanism of synergetic innovation on industrial clusters according to these theoretical results. Firstly, we analyze the behavior of synergetic innovation on industrial clusters from a microeconomic point of view. Secondly, we explain component elements of synergetic innovative system. Lastly, we discuss the formative process of synergetic innovation in detail. Thus we can provide synergetic innovation of cluster companies with theoretical guidelines.展开更多
The intellectual property (IP) benefits allocation is a major problem in collaborative innovation, because the collaborative partners have different benefits pursues, and they make the allocation of ownership and bene...The intellectual property (IP) benefits allocation is a major problem in collaborative innovation, because the collaborative partners have different benefits pursues, and they make the allocation of ownership and benefits complicated. If the interests can’t be allocated properly, then the conflicts will occur between the collaborative partners and collaborative relationship can’t last long, so we focus on the benefits allocation mechanism of IP to ensure each participated partner can get the benefits fairly. Some scholars noticed the importance of IP benefits allocation and conducted theoretical research, which provided model and theoretical analysis, but these research contents were not comprehensive, the research methods and evidences seemed inadequate, which leaded the conclusions into?having limited meaning. Thus, we use case study and investigate regional-development oriented collaborative innovation center to examine the benefits allocation mechanism. We find out the problems in the existing benefits allocation mechanism, such as the compensation and rewards are not enough, the benefits allocation should be fair, the payment way is not various and so on. Based on the case study on the status quo and combined with related needs, we put forward that ensure the ownership of IP, attention on regulation construction, benefits protection and so on. We hope this study can solve these problems through case analysis, and benefit to maintain collaborative relationship.展开更多
Based on the analysis of the formation process of regional innovation capacity, this paper expatiates that the technology is the basis for industrial structure upgrading, while technological innovation is the power of...Based on the analysis of the formation process of regional innovation capacity, this paper expatiates that the technology is the basis for industrial structure upgrading, while technological innovation is the power of regional innovation capacity. It points out that the essential of regional industrial structure upgrading is the transition of regional technology structure from one balance to another. The mechanism of realizing industrial structure upgrading through technology-driven regional innovation capacity is also discussed briefly.展开更多
This paper expounds the necessity of constructing China's rural multiplex financial system as follows.First,overcome the bottleneck effect arising from the shortage of capital in the process of development of rura...This paper expounds the necessity of constructing China's rural multiplex financial system as follows.First,overcome the bottleneck effect arising from the shortage of capital in the process of development of rural small and medium-sized enterprise,and increase farmers' income;second,provide capital support for rural modern industrial development,and promote rural economic development;third,rationally allocate capital,master the money flow and coordinate urban-rural development.The paper also profoundly analyzes the difficulties of constructing China's rural multiplex financial system as follows.First,the existing rural financial system structure is irrational and the function is unsound;second,non-governmental financial market is disorderly and the organization is unsound;third,the rural financial system is simple and the overhaul of rural credit cooperatives system has not yet been done;fourth,the construction of rural system of financial laws and regulations is laggard,and the construction of rural multiplex financial system lacks good social environment.The specific thoughts,measures and countermeasures of constructing mechanism innovation of China's rural multiplex financial system are put forward as follows.First,increasingly perfect legal system and provide legal support for constructing China's rural multiplex financial system;second,quicken the overhaul of rural credit cooperatives system and perfect its function in China's rural multiplex financial system;third,strengthen the degree of support and development,and change the situation of simple structure of rural financial system;fourth,reinforce administrative supervision and perfect public services,and standardize the rural financial market order.展开更多
The far-field microdynamic disturbance caused by the excavation of deep mineral resources and underground engineering can induce surrounding rock damage in high-stress conditions and even lead to disasters.However,the...The far-field microdynamic disturbance caused by the excavation of deep mineral resources and underground engineering can induce surrounding rock damage in high-stress conditions and even lead to disasters.However,the mechanical properties and damage/fracture evolution mechanisms of deep rock induced by microdynamic disturbance under three-dimensional stress states are unclear.Therefore,a true triaxial multilevel disturbance test method is proposed,which can completely simulate natural geostress,excavation stress redistribution(such as stress unloading,concentration and rotation),and subsequently the microdynamic disturbance triggering damaged rock failure.Based on a dynamic true triaxial test platform,true triaxial microdynamic disturbance tests under different frequency and amplitudes were carried out on monzogabbro.The results show that increasing amplitude or decreasing frequency diminishes the failure strength of monzogabbro.Deformation modulus gradually decreases during disturbance failure.As frequency and amplitude increase,the degradation rate of deformation modulus decreases slightly,disturbance dissipated energy increases significantly,and disturbance deformation anisotropy strengthens obviously.A damage model has been proposed to quantitatively characterize the disturbance-induced damage evolution at different frequency and amplitude under true triaxial stress.Before disturbance failure,the micro-tensile crack mechanism is dominant,and the micro-shear crack mechanism increases significantly at failure.With the increase of amplitude and frequency,the micro-shear crack mechanism increases.When approaching disturbance failure,the acoustic emission fractal dimension changes from a stable value to local large oscillation,and finally increases sharply to a high value at failure.Finally,the disturbance-induced failure mechanism of surrounding rock in deep engineering is clearly elucidated.展开更多
基金Under the auspices of the National Natural Science Foundation of China(No.42076222)。
文摘Marine science technology innovation provides power and guarantees for marine eco-civilization construction,which provides direction and material support for marine science technology innovation.Therefore,the coordinated development of the two is of great significance to the marine economy sustainable development in China’s coastal areas.On the basis of clarifying the connotations of marine science technology innovation and marine eco-civilization in China’s coastal areas from 2006 to 2019,the mechanism for their coordinated development was analysed.A comprehensive indicator system based on the connotation of the two was constructed,and the coordinated development relationship was empirically tested using the coupled coordination model and the panel vector autoregressive(PVAR)model.The results show that:1)the level of China’s coastal marine science technology innovation continues to improve,gradually forming the core of the development of marine science technology innovation in the north,east and south of Shandong,Shanghai and Guangdong;the level of marine eco-civilization development fluctuating upward trend,showing obvious spatial differentiation characteristics.2)The degree of coordination of marine science technology innovation and marine eco-civilization is growing over time.There is no causal relationship between marine science technology innovation and marine eco-civilization in the northern marine economic circle,but there is a two-way causal relationship between the two in the eastern and southern marine economic circles.3)Marine eco-civilization shows a significant positive and continuous impact on marine science technology innovation,and marine science technology innovation shows a long-term,continuous,fluctuating,and lagging impact on marine eco-civilization.The overall role of marine eco-civilization on marine science technology innovation is dominant,and there are significant differences in the impact effects of the two major marine economic circles.
基金This paper is funded by Humanities and Social Sciences Research Project of the Ministry of Education:The Research on the Influence Mechanism of Chinese Enterprise Employees’Participation on Adaptive Performance—An Explanation Based on the JDR Theory and Self-Consistency Theory(19YJC630226)Soft Science Project of Hebei Provincial Department of Science and Technology:The Research on the Incentive Mechanism for Innovation of Sci-Tech Talents in Hebei Province from the Perspective of AMO Theory(225576109D)Humanities and Social Sciences Foundation of Hebei Normal University:The Research on the Influence Mechanism of Enterprise Employees’Participation on Growth Performance in the Context of Technological Change(S20GD009).
文摘With the implementation of China’s innovation-driven development strategy,the competition among sci-tech talents has become increasingly fierce.Stimulating the innovative vigor of sci-tech talents has become a hot topic in theoretical research and policy practice.Based on the data from 246 questionnaires collected from sci-tech talents in Hebei province,this study explored the influence mechanism of an inclusive organizational climate on innovation input from technological talents and verified the mediating effects of innovation self-efficacy and intrinsic motivation.The results indicate that an inclusive organizational climate has a significant positive impact on innovation input,innovation self-efficacy,and intrinsic motivation of sci-tech talents.Both innovation self-efficacy and intrinsic motivation play a partial mediating role between an inclusive climate and innovation input.This study verified the important role of an inclusive climate in an organization’s human resource management practices and encouraged managers to emphasize enhancing the innovation self-efficacy and intrinsic motivation of sci-tech talents,thereby continuously improving the level of innovation.
文摘The Pudong New Area has followed the standardization polices of the country,vigorously implemented the standardization strategies,and fulfilled the historical mission of“serving as a pioneer of reform&opening-up and innovative development”.
文摘Against the backdrop of rapid global economic development,the demand for education has gradually shifted from quantitative growth to qualitative improvement.Vocational education,higher education,and continuing education are crucial components of China’s education system,each serving different educational functions.However,the collaborative innovation among these three types of education is still in the preliminary exploration stage,with issues such as scattered resources and imperfect coordination mechanisms.This paper systematically reviews relevant domestic and international research and practical experiences,thoroughly analyzes the pathways,models,and mechanisms of collaborative innovation among these three types of education,and proposes practical and operational suggestions based on the actual situation in Xuzhou City.The study finds that collaboration between vocational education,higher education,and continuing education through innovation not only enhances the overall efficiency of educational resources but also promotes regional economic development and social progress.On this basis,this paper proposes specific measures such as building an education resource-sharing platform,promoting a chain-based talent training system,strengthening policy and institutional guarantees,and improving incentive mechanisms,aiming to provide a reference for local education administrators and contribute to the innovative development of education in China.
基金supported by PTDC-01778/2022-NeuroDev3D,iNOVA4Health(UIDB/04462/2020 and UIDP/04462/2020)LS4FUTURE(LA/P/0087/2020)。
文摘Cells,tissues,and organs are constantly subjected to the action of mechanical forces from the extracellular environment-and the nervous system is no exception.Cell-intrinsic properties such as membrane lipid composition,abundance of mechanosensors,and cytoskeletal dynamics make cells more or less likely to sense these forces.Intrinsic and extrinsic cues are integrated by cells and this combined information determines the rate and dynamics of membrane protrusion growth or retraction(Yamada and Sixt,2019).Cell protrusions are extensions of the plasma membrane that play crucial roles in diverse contexts such as cell migration and neuronal synapse formation.In the nervous system,neurons are highly dynamic cells that can change the size and number of their pre-and postsynaptic elements(called synaptic boutons and dendritic spines,respectively),in response to changes in the levels of synaptic activity through a process called plasticity.Synaptic plasticity is a hallmark of the nervous system and is present throughout our lives,being required for functions like memory formation or the learning of new motor skills(Minegishi et al.,2023;Pillai and Franze,2024).
基金Shenzhen Polytechnical University School level Scientific Research Projects 2023:“Research on the Path and Mechanism of Equity Investment in the Innovation Achievement Transformation of New Material Industry from the Perspective of Intermediary Effect”(Project No.6023310014S)Shenzhen Polytechnical University Postdoctoral Outstation Late Stage Funding Project:“Research on the Cultivation of Digital Trade Talents in the Guangdong Hong Kong Macao Greater Bay Area”(Project No.6023271012S)。
文摘Under the wave of global technological revolution,the new materials industry is facing difficulties in innovation and transformation.Equity investment has become a key driving force due to its flexible mechanism,risk sharing,and deep participation.Based on introducing the current development status of China’s new materials industry,this article reveals the mechanism of equity investment in financial support,risk management,incentive constraints,and resource integration.The article proposes optimization strategies,such as building an information-sharing mechanism and a diversified investment fund system,to promote the high-quality development of the new materials industry driven by innovation and provide strategic guidance for policymakers,investors,and enterprises.
文摘The complex morphological,anatomical,physiological,and chemical mechanisms within the aging brain have been the hot topic of research for centuries.The aging process alters the brain structure that affects functions and cognitions,but the worsening of such processes contributes to the pathogenesis of neurodegenerative disorders,such as Alzheimer's disease.Beyond these observable,mild morphological shifts,significant functional modifications in neurotransmission and neuronal activity critically influence the aging brain.Understanding these changes is important for maintaining cognitive health,especially given the increasing prevalence of age-related conditions that affect cognition.This review aims to explore the age-induced changes in brain plasticity and molecular processes,differentiating normal aging from the pathogenesis of Alzheimer's disease,thereby providing insights into predicting the risk of dementia,particularly Alzheimer's disease.
基金supported by the Natural Science Foundation of Fujian Province,No.2021J02035(to WX).
文摘Regulated cell death is a form of cell death that is actively controlled by biomolecules.Several studies have shown that regulated cell death plays a key role after spinal cord injury.Pyroptosis and ferroptosis are newly discovered types of regulated cell deaths that have been shown to exacerbate inflammation and lead to cell death in damaged spinal cords.Autophagy,a complex form of cell death that is interconnected with various regulated cell death mechanisms,has garnered significant attention in the study of spinal cord injury.This injury triggers not only cell death but also cellular survival responses.Multiple signaling pathways play pivotal roles in influencing the processes of both deterioration and repair in spinal cord injury by regulating pyroptosis,ferroptosis,and autophagy.Therefore,this review aims to comprehensively examine the mechanisms underlying regulated cell deaths,the signaling pathways that modulate these mechanisms,and the potential therapeutic targets for spinal cord injury.Our analysis suggests that targeting the common regulatory signaling pathways of different regulated cell deaths could be a promising strategy to promote cell survival and enhance the repair of spinal cord injury.Moreover,a holistic approach that incorporates multiple regulated cell deaths and their regulatory pathways presents a promising multi-target therapeutic strategy for the management of spinal cord injury.
文摘In order to improve the cigarette enterprise technology innovation and patent management status, the macro work should start from the four aspects of patent ideology introduction, patent organization design, perfecting patent system and implementation of specific measures, and attention should be attached to strengthen the cooperation of the cigarette enterprise management departments. On the other hand, Jn the microscopic work level, it should build the culture atmosphere of the entire tobacco industry respect intellectual property rights, actively cultivate the na- tional patent agents and patent engineers, and gradually promote the patent work to develop in the direction of specialization, self-independence, so as to construct a scientific mechanism for patent management, and enhance the core competitiveness of the tobacco industry.
文摘The rationality and scientific nature of the emission trading mechanism is the key to the effective implementation of environmental and economic policies.As far as China is concerned,there are phenomena such as information asymmetry,low supervision efficiency,and alienation of government and enterprise behaviors caused by the incomplete mechanism of emission trading in the practice of different pilots.The introduction of blockchain technology can innovate the traditional transaction model and form a decentralized peer-to-peer transaction and a trusted emission trading market.To this end,based on the current emission trading mechanism and the characteristics of blockchain technology,this paper couples the core technologies of blockchain with the functional requirements of application scenarios.Then,an innovative application framework is built based on the consortium blockchain Fabric from three aspects:emission trading supervision,secondary trading market construction,as well as emission trading incentive and punishment mechanisms.Technologies such as the consensus mechanism,smart contract,Merkle tree and asymmetric encryption are comprehensively applied in this process.In the construction of the blockchain framework of the secondary market for emission trading,institutional changes and innovations brought about by the blockchain at various levels are analyzed in terms of participants,transaction processes and the transaction scope.At the same time,smart contract functions and algorithms are designed for the purchase,transfer-out and trading of emission rights,and the operation business logic of the smart contract is analyzed.On the whole,this paper explores the application framework of blockchain technology in the field of emission trading at the macro level,and analyzes the application mechanism of the corresponding technologies of blockchain at each coupling point in the framework at the micro level.The collaborative analysis at the two levels shows that blockchain technology and the requirements of emission trading mechanism can be effectively coupled,and the application of blockchain technology can promote the effective supervision of enterprises'emission behavior,making the processes of the purchase,transfer and transaction of emission rights intelligent and automated,and providing technical support for cross regional emission trading to reduce transaction costs and management complexity.In addition,the issuance of emission credits based on smart contract will be a new incentive for companies to actively participate in transactions.Based on the above analysis,this paper believes that the innovative application of blockchain technology is of great significance in the promotion of the market-based allocation of element of emission trading and the rational allocation of environmental resources.It will lead to a major breakthrough in the traditional trading system in terms of trading modes,forming a value transmission network of environmental resources between the government and polluters.
基金Soft Science Project of Science&Technology Department of Henan Province(172400410342).
文摘In the current process of deepening reform in China,industrial structure upgrading,economic structural transformation and new urbanization are important tasks to promote social and economic development,and technological innovation has gradually become the primary driving force for industrial upgrading,economic transformation and the realization of new urbanization.The article analyzed the action mechanism of scientific and technological innovation on the integration of industrialization and urbanization through qualitative and quantitative methods,found out the prominent problems faced by Henan through the empirical analysis of relevant data of Henan Province,and then proposed the integrated development path driven by scientific and technological innovation.
基金Supported by Educational Science Research Project of Shanghai City(C16064)
文摘Based on the review of related concepts,the current situation and problems of talent training in marine cultural industry in China were analyzed,and talent training mechanisms of marine cultural industry based on collaborative innovation of governments,enterprises,colleges,scientific institutions and users were proposed to promote the transformation,upgrading and vigorous development of marine cultural industry,accelerate the spread of marine culture with Chinese characteristics,and build China into a maritime power.
文摘E-commerce is a new business model based on Internet information technology,and its internal operation mechanism can be studied in depth from the perspective of the knowledge ecosystem according to the law of knowledge ecology.The various knowledge elements in the e-business knowledge ecosystem interact and influence each other,continue to exchange materials and energy according to specific rules,and develop and circulate autonomously so that users can acquire,transfer,share and sublimate knowledge in the business system.Finally,knowledge innovation and new value creation are realized to complete the final value sublimation.Based on this,this paper elaborates on three aspects of e-business ecosystem system synergy theory,e-business ecosystem,and e-business ecosystem synergy and innovation model for the reference of relevant personnel.
文摘In this paper, we conduct research on the big data and the artificial intelligence aided decision-making mechanism with the applications on video website homemade program innovation. Make homemade video shows new media platform site content production with new possible, as also make the traditional media found in Internet age, the breakthrough point of the times. Site homemade video program, which is beneficial to reduce copyright purchase demand, reduce the cost, avoid the homogeneity competition, rich advertising marketing at the same time, improve the profit pattern, the organic combination of content production and operation, complete the strategic transformation. On the basis of these advantages, once the site of homemade video program to form a brand and a higher brand influence. Our later research provides the literature survey for the related issues.
文摘The connotation of rural public goods is expounded.The rural public goods refer to the products and labors that satisfy the production and living of rural residents,economic growth and social progress.The rural public goods is characterized by non-excludability,non-competitiveness and indispensability of other general public goods.The supply situation of Chinese government to rural public goods is analyzed,as well as the demand situation of rural public goods,which includes farmers' demand on training,the assistance demand of rural weak groups,farmers' demand on comfortable living conditions and farmers' demand on "soft" public goods.The paths for innovating the supply mechanism of rural public goods are put forward,which cover perfecting the decision mechanism of public goods supply;scientifically distributing the supply responsibility of rural public goods;facilitating the reform of each supporting equipment and exploring the multiple capital collecting channels of rural public goods.
文摘The paper summarizes domestic and overseas research results on synergetic innovation. Then it discusses the mechanism of synergetic innovation on industrial clusters according to these theoretical results. Firstly, we analyze the behavior of synergetic innovation on industrial clusters from a microeconomic point of view. Secondly, we explain component elements of synergetic innovative system. Lastly, we discuss the formative process of synergetic innovation in detail. Thus we can provide synergetic innovation of cluster companies with theoretical guidelines.
文摘The intellectual property (IP) benefits allocation is a major problem in collaborative innovation, because the collaborative partners have different benefits pursues, and they make the allocation of ownership and benefits complicated. If the interests can’t be allocated properly, then the conflicts will occur between the collaborative partners and collaborative relationship can’t last long, so we focus on the benefits allocation mechanism of IP to ensure each participated partner can get the benefits fairly. Some scholars noticed the importance of IP benefits allocation and conducted theoretical research, which provided model and theoretical analysis, but these research contents were not comprehensive, the research methods and evidences seemed inadequate, which leaded the conclusions into?having limited meaning. Thus, we use case study and investigate regional-development oriented collaborative innovation center to examine the benefits allocation mechanism. We find out the problems in the existing benefits allocation mechanism, such as the compensation and rewards are not enough, the benefits allocation should be fair, the payment way is not various and so on. Based on the case study on the status quo and combined with related needs, we put forward that ensure the ownership of IP, attention on regulation construction, benefits protection and so on. We hope this study can solve these problems through case analysis, and benefit to maintain collaborative relationship.
文摘Based on the analysis of the formation process of regional innovation capacity, this paper expatiates that the technology is the basis for industrial structure upgrading, while technological innovation is the power of regional innovation capacity. It points out that the essential of regional industrial structure upgrading is the transition of regional technology structure from one balance to another. The mechanism of realizing industrial structure upgrading through technology-driven regional innovation capacity is also discussed briefly.
文摘This paper expounds the necessity of constructing China's rural multiplex financial system as follows.First,overcome the bottleneck effect arising from the shortage of capital in the process of development of rural small and medium-sized enterprise,and increase farmers' income;second,provide capital support for rural modern industrial development,and promote rural economic development;third,rationally allocate capital,master the money flow and coordinate urban-rural development.The paper also profoundly analyzes the difficulties of constructing China's rural multiplex financial system as follows.First,the existing rural financial system structure is irrational and the function is unsound;second,non-governmental financial market is disorderly and the organization is unsound;third,the rural financial system is simple and the overhaul of rural credit cooperatives system has not yet been done;fourth,the construction of rural system of financial laws and regulations is laggard,and the construction of rural multiplex financial system lacks good social environment.The specific thoughts,measures and countermeasures of constructing mechanism innovation of China's rural multiplex financial system are put forward as follows.First,increasingly perfect legal system and provide legal support for constructing China's rural multiplex financial system;second,quicken the overhaul of rural credit cooperatives system and perfect its function in China's rural multiplex financial system;third,strengthen the degree of support and development,and change the situation of simple structure of rural financial system;fourth,reinforce administrative supervision and perfect public services,and standardize the rural financial market order.
基金the financial support from the National Natural Science Foundation of China(No.52109119)the Guangxi Natural Science Foundation(No.2021GXNSFBA075030)+2 种基金the Guangxi Science and Technology Project(No.Guike AD20325002)the Chinese Postdoctoral Science Fund Project(No.2022M723408)the Open Research Fund of State Key Laboratory of Simulation and Regulation of Water Cycle in River Basin(China Institute of Water Resources and Hydropower Research)(No.IWHR-SKL-202202)。
文摘The far-field microdynamic disturbance caused by the excavation of deep mineral resources and underground engineering can induce surrounding rock damage in high-stress conditions and even lead to disasters.However,the mechanical properties and damage/fracture evolution mechanisms of deep rock induced by microdynamic disturbance under three-dimensional stress states are unclear.Therefore,a true triaxial multilevel disturbance test method is proposed,which can completely simulate natural geostress,excavation stress redistribution(such as stress unloading,concentration and rotation),and subsequently the microdynamic disturbance triggering damaged rock failure.Based on a dynamic true triaxial test platform,true triaxial microdynamic disturbance tests under different frequency and amplitudes were carried out on monzogabbro.The results show that increasing amplitude or decreasing frequency diminishes the failure strength of monzogabbro.Deformation modulus gradually decreases during disturbance failure.As frequency and amplitude increase,the degradation rate of deformation modulus decreases slightly,disturbance dissipated energy increases significantly,and disturbance deformation anisotropy strengthens obviously.A damage model has been proposed to quantitatively characterize the disturbance-induced damage evolution at different frequency and amplitude under true triaxial stress.Before disturbance failure,the micro-tensile crack mechanism is dominant,and the micro-shear crack mechanism increases significantly at failure.With the increase of amplitude and frequency,the micro-shear crack mechanism increases.When approaching disturbance failure,the acoustic emission fractal dimension changes from a stable value to local large oscillation,and finally increases sharply to a high value at failure.Finally,the disturbance-induced failure mechanism of surrounding rock in deep engineering is clearly elucidated.