The preoptic area (POA) is located in the most anterior part of the hypothalamus and is bordered dorsally by the anterior commissure and anteroventrally by the nucleus of the diagonal band of Broca[1]. Accumulating ...The preoptic area (POA) is located in the most anterior part of the hypothalamus and is bordered dorsally by the anterior commissure and anteroventrally by the nucleus of the diagonal band of Broca[1]. Accumulating evidence from developmental neurobiology suggests, however, that the POA may be a separate entity from hypothalamus, and may actually be part of the basal telencephalon[2,3]. Both the hypothalamus and POA are highly complex and heterogeneous areas, containing multiple nuclei, each of which has specific fundamental functions for survival. Among these, the POA contains nuclei involved in the regulation of blood osmolality and temperature (the median preoptic nucleus), sleep (the ventrolateral preoptic and suprachiasmatic nuclei), ovulation (gonadotropin-releasing hormone neurons scattered mainly in the ventral part of the POA), male sexual behavior (the medial preoptic nucleus), and parental behavior (the central part of the medial POA, cMPOA).展开更多
文摘The preoptic area (POA) is located in the most anterior part of the hypothalamus and is bordered dorsally by the anterior commissure and anteroventrally by the nucleus of the diagonal band of Broca[1]. Accumulating evidence from developmental neurobiology suggests, however, that the POA may be a separate entity from hypothalamus, and may actually be part of the basal telencephalon[2,3]. Both the hypothalamus and POA are highly complex and heterogeneous areas, containing multiple nuclei, each of which has specific fundamental functions for survival. Among these, the POA contains nuclei involved in the regulation of blood osmolality and temperature (the median preoptic nucleus), sleep (the ventrolateral preoptic and suprachiasmatic nuclei), ovulation (gonadotropin-releasing hormone neurons scattered mainly in the ventral part of the POA), male sexual behavior (the medial preoptic nucleus), and parental behavior (the central part of the medial POA, cMPOA).