Recent advances in big and streaming data systems have enabled real-time analysis of data generated by Internet of Things(IoT)systems and sensors in various domains.In this context,many applications require integratin...Recent advances in big and streaming data systems have enabled real-time analysis of data generated by Internet of Things(IoT)systems and sensors in various domains.In this context,many applications require integrating data from several heterogeneous sources,either stream or static sources.Frameworks such as Apache Spark are able to integrate and process large datasets from different sources.However,these frameworks are hard to use when the data sources are heterogeneous and numerous.To address this issue,we propose a system based on mediation techniques for integrating stream and static data sources.The integration process of our system consists of three main steps:configuration,query expression and query execution.In the configuration step,an administrator designs a mediated schema and defines mapping between the mediated schema and local data sources.In the query expression step,users express queries using customized SQL grammar on the mediated schema.Finally,our system rewrites the query into an optimized Spark application and submits the application to a Spark cluster.The results are continuously returned to users.Our experiments show that our optimizations can improve query execution time by up to one order of magnitude,making complex streaming and spatial data analysis more accessible.展开更多
BACKGROUND Emotional reactions,such as anxiety,irritability,and aggressive behavior,have attracted clinical attention as behavioral and emotional problems in preschool-age children.AIM To investigate the current statu...BACKGROUND Emotional reactions,such as anxiety,irritability,and aggressive behavior,have attracted clinical attention as behavioral and emotional problems in preschool-age children.AIM To investigate the current status of family rearing,parental stress,and behavioral and emotional problems of preschool children and to analyze the mediating effect of the current status of family rearing on parental stress and behavioral/emo-tional problems.METHODS We use convenience sampling to select 258 preschool children in the physical examination center of our hospital from October 2021 to September 2023.The children and their parents were evaluated using a questionnaire survey.Pearson's correlation was used to analyze the correlation between child behavioral and emotional problems and parental stress and family rearing,and the structural equation model was constructed to test the mediating effect.RESULTS The score for behavioral/emotional problems of 258 preschool children was(27.54±3.63),the score for parental stress was(87.64±11.34),and the score for parental family rearing was(31.54±5.24).There was a positive correlation between the behavioral and emotional problems of the children and the“hostile/mandatory”parenting style;meanwhile,showed a negative correlation with the“support/participation”parenting style(all P<0.05).The intermediary effect value between the family upbringing of parents in parental stress and children's behavior problems was 29.89%.CONCLUSION Parental family upbringing has a mediating effect between parental stress and behavioral and emotional problems of children.Despite paying attention to the behavioral and emotional problems of preschool-age children,clinical medical staff should provide correct and reasonable parenting advice to their parents to promote the mental health of preschool-age children.展开更多
BACKGROUND Depression is a prevalent psychological issue in adolescents that is significantly related to negative life events(NLEs)and dysfunctional attitudes.High levels of social support can significantly buffer NLE...BACKGROUND Depression is a prevalent psychological issue in adolescents that is significantly related to negative life events(NLEs)and dysfunctional attitudes.High levels of social support can significantly buffer NLEs’effect on depression.Currently,there is limited research on how social support moderates the relationship between NLEs,dysfunctional attitudes,and depression in adolescents in China.It is imperative to investigate this moderating effect to mitigate dysfunctional attitudes in adolescent undergoing depressive mood,ultimately enhancing their overall mental health.AIM To investigate the relationship and underlying mechanisms between specific dysfunctional attitudes,social support,and depression among Chinese adolescents.METHODS This is a cross-sectional study which selected five middle schools in Shandong Province for investigation in March 2022.Participants included 795 adolescents(49.87%male,mage=15.15,SD=1.84,age range=11-18 years old).All participants completed the Dysfunctional Attitude Scale,Adolescent Life Event Scale,Beck Depression Inventory,and Social Support Rating Scale.A moderated mediation model was conducted to examine the relationship between specific dysfunctional attitudes,social support,and depression.RESULTS Results indicated that NLEs affected depression through the mediating role of specific dysfunctional attitudes(autonomy attitudesβ=0.21;perfectionismβ=0.25).Moreover,social support was found to moderate the mediating effect between NLEs,specific dysfunctional attitudes,and depressive symptoms(autonomy attitudes b2=-0.08;perfectionism b2=-0.09).CONCLUSION Dysfunctional attitudes mediated and social support moderated the relationship between NLEs and depression.Social support can buffer depression symptoms among adolescents with autonomy attitudes and perfectionism.展开更多
Implementing a new energy-saving electrochemical synthesis system with high commercial value is a strategy of the sustainable development for upgrading the bulk chemicals preparation technology in the future.Here,we r...Implementing a new energy-saving electrochemical synthesis system with high commercial value is a strategy of the sustainable development for upgrading the bulk chemicals preparation technology in the future.Here,we report a multiple redox-mediated linear paired electrolysis system,combining the hydrogen peroxide mediated cathode process with the I2 mediated anode process,and realize the conversion of furfural to furoic acid in both side of the dividedflow cell simultaneously.By reasonably controlling the cathode potential,the undesired water splitting reaction and furfural reduction side reactions are avoided.Under the galvanostatic electrolysis,the two-mediated electrode processes have good compatibility,which reduce the energy consumption by about 22%while improving the electronic efficiency by about 125%.This system provides a green electrochemical synthesis route with commercial prospects.展开更多
Background:In addition to healthcare entitlements,‘migrant-friendly health services’in Thailand include interpretation and cultural mediation services which aim to reduce language and cultural barriers between healt...Background:In addition to healthcare entitlements,‘migrant-friendly health services’in Thailand include interpretation and cultural mediation services which aim to reduce language and cultural barriers between health personnel and migrants.Although the Thai Government started implementing these services in 2003,challenges in providing them still remain.This study aims to analyse the health system functions which support the interpretation and cultural mediation services of migrant health worker(MHW)and migrant health volunteer(MHV)programmes in Thailand.Methods:In-depth interviews were conducted in two migrant-populated provinces using purposive and snowball sampling.A total of fifty key informants were recruited,including MHWs,MHVs,health professionals,non-governmental organisation(NGO)staff and policy stakeholders.Data were triangulated using information from policy documents.The deductive thematic analysis was classified into three main themes of evolving structure of MHW and MHV programmes,roles and responsibilities of MHWs and MHVs,and supporting systems.Results:The introduction of the MHW and MHV programmes was one of the most prominent steps taken to improve the migrant-friendliness of Thai health services.MHWs mainly served as interpreters in public facilities,while MHVs served as cultural mediators in migrant communities.Operational challenges in providing services included insufficient budgets for employment and training,diverse training curricula,and lack of legal provisions to sustain the MHW and MHV programmes.Conclusion:Interpretation and cultural mediation services are hugely beneficial in addressing the health needs of migrants.To ensure the sustainability of current service provision,clear policy regulation and standardised training courses should be in place,alongside adequate and sustainable financial support from central government,NGOs,employers and migrant workers themselves.Moreover,regular monitoring and evaluation of the quality of services are recommended.Finally,a lead agency should be mandated to collaborate with stakeholders in planning the overall structure and resource allocation for the programmes.展开更多
Background:College students face significant academic and physiological changes,making them more susceptible to psychological issues such as depression,self-injury,and suicidal ideation.Feelings of defeat can exacerba...Background:College students face significant academic and physiological changes,making them more susceptible to psychological issues such as depression,self-injury,and suicidal ideation.Feelings of defeat can exacerbate these risks by increasing academic stress.However,interpersonal relationships can moderate the impact of academic stress on students’mental health.Utilizing the presage–process–product model,this study aims to empirically investigate how feelings of defeat influence depression,self-injury,and suicidal ideation among college students.Additionally,it explores the mediating role of academic stress and the moderating role of various types of interpersonal relationships.Methods:A total of 1612 college students(750 females,862 males,mean age=19.64±0.62 years)were recruited through cluster sampling.Data were collected via offline questionnaires administered by a trained psychology teacher and a postgraduate student,ensuring high reliability with two examiners per class.Latent profile analysis(LPA)was used to examine the impact of defeat on mental health outcomes,while mediation analysis was conducted to assess the roles of academic stress and interpersonal relationships.Results:1.Defeat is identified as a significant risk factor for mental health issues among college students;2.Four distinct patterns of interpersonal relationships were identified:the interpersonal-relationship risk group,the father–child-relationship high-risk group,the general interpersonal-relationship group,and the superior interpersonal-relationship group;3.Academic stress partially mediates the relationship between defeat and mental health issues such as depression,self-injury,and suicidal ideation;4.Different interpersonal relationship models moderate the impact of academic stress on depression and suicidal ideation.Conclusion:Defeat is a significant risk factor for mental health problems in college students.Academic stress partially mediates the negative impact of defeat on mental health,while patterns of interpersonal relationships moderate this impact.Effective early prevention and intervention should focus on monitoring students’stress levels and fostering warm,positive parent–child relationships.展开更多
Internet gaming disorder(IGD)among junior high school students is an increasingly prominent mental health concern.It is important to look for influences behind internet gaming disorder tendency(IGDT)in the junior high...Internet gaming disorder(IGD)among junior high school students is an increasingly prominent mental health concern.It is important to look for influences behind internet gaming disorder tendency(IGDT)in the junior high school student population.The present study aimed to reveal the explanatory mechanisms underlying the association between parental psychological control(PPC)and internet gaming disorder tendency among junior high school students by testing the mediating role of core self-evaluation(CSE)and the moderating role of intentional self-regulation(ISR).Participants in present study were 735 Chinese junior high school students who completed offline self-report questionnaires on parental psychological control,core self-evaluation,intentional self-regulation,and Internet gaming disorder tendency.Analyses were conducted via mediation and moderated mediation.The results showed that:(1)Parental psychological control was positively related to junior high school students’Internet gaming disorder tendency.Core self-evaluation,and intentional self-regulation were negatively related to junior high school students’Internet gaming disorder tendency,respectively.(2)Core self-evaluation partially mediated the relationship between parental psychological control and junior high school students’Internet gaming disorder tendency.(3)Intentional self-regulation moderated the association between parental psychological control and Internet gaming disorder tendency,as well as the relationships between parental psychological control and core self-evaluation and core self-evaluation and Internet gaming disorder tendency in the mediated model.Based on these findings,we believe that there is a need to weaken parental psychological control,strengthen junior high school students’core self-evaluation and intentional self-regulation,and to recognize the important role of parents as well as their children’s personal positive traits in the healthy development of junior high school students.展开更多
Colorectal cancer(CRC)poses significant physical and psychological challenges that necessitate an exploration of factors influencing post-traumatic growth(PTG)for patient well-being.This study aims to investigate the ef...Colorectal cancer(CRC)poses significant physical and psychological challenges that necessitate an exploration of factors influencing post-traumatic growth(PTG)for patient well-being.This study aims to investigate the effects of positive psychological capital(PsyCap)and perceived stress on mediating the social support-PTG relation among 673 CRC patients.Social support,positive PsyCap,perceived stress,and PTG were assessed through questionnaires.The results indicated a direct prediction effect of social support on PTG(LICI=0.481,ULCI=0.644),with the direct effect being 59.5%.Both positive PsyCap and perceived stress exerted a mediating role in the correlation between social support and PTG,with the mediating effects occupying 29.4%(LICI=0.217,ULCI=0.343)and 5.7%(LICI=0.030,ULCI=0.082),respectively.Positive PsyCap further had a chain mediating effect on perceived stress(LICI=0.031,ULCI=0.074),with the chain effect accounting for 5.4%.The total impact of social support on PTG was 100%(LICI=0.882,ULCI=1.008).This model underscores the pivotal role of social support in promoting PTG in CRC patients.Positive PsyCap serves as a crucial mediator in the social support-PTG link,with perceived stress playing a sequential mediating role.Thesefindings suggest that strengthening social support networks and cultivating positive PsyCap may reduce perceived stress and promote the development of PTG in CRC patients.Consequently,intervention programs are recommended to improve the psychosocial well-being of CRC patients.展开更多
With the rise of new media and short videos shaping the new communication environment,rural culture has been mediated and transformed to spread to a wider region.As a cultural achievement of rural revitalization,“Vil...With the rise of new media and short videos shaping the new communication environment,rural culture has been mediated and transformed to spread to a wider region.As a cultural achievement of rural revitalization,“Village BA”(Village Basketball Association)demonstrates Chinese modernization.The use of short videos,mass rural movements,and“spectacle”spaces to attract spectators has become a key issue in the dissemination of rural culture.展开更多
Specialized pro-resolving lipid mediators including maresin 1 mediate resolution but the levels of these are reduced in Alzheimer's disease brain, suggesting that they constitute a novel target for the treatment o...Specialized pro-resolving lipid mediators including maresin 1 mediate resolution but the levels of these are reduced in Alzheimer's disease brain, suggesting that they constitute a novel target for the treatment of Alzheimer's disease to prevent/stop inflammation and combat disease pathology. Therefore, it is important to clarify whether they counteract the expression of genes and proteins induced by amyloid-β. With this objective, we analyzed the relevance of human monocyte–derived microglia for in vitro modeling of neuroinflammation and its resolution in the context of Alzheimer's disease and investigated the pro-resolving bioactivity of maresin 1 on amyloid-β42–induced Alzheimer's disease–like inflammation. Analysis of RNA-sequencing data and secreted proteins in supernatants from the monocyte-derived microglia showed that the monocyte-derived microglia resembled Alzheimer's disease–like neuroinflammation in human brain microglia after incubation with amyloid-β42. Maresin 1 restored homeostasis by down-regulating inflammatory pathway related gene expression induced by amyloid-β42 in monocyte-derived microglia, protection of maresin 1 against the effects of amyloid-β42 is mediated by a re-balancing of inflammatory transcriptional networks in which modulation of gene transcription in the nuclear factor-kappa B pathway plays a major part. We pinpointed molecular targets that are associated with both neuroinflammation in Alzheimer's disease and therapeutic targets by maresin 1. In conclusion, monocyte-derived microglia represent a relevant in vitro microglial model for studies on Alzheimer's disease-like inflammation and drug response for individual patients. Maresin 1 ameliorates amyloid-β42–induced changes in several genes of importance in Alzheimer's disease, highlighting its potential as a therapeutic target for Alzheimer's disease.展开更多
Mediation is becoming more and more important in the process of settling conflict nowadays,so it’s quite necessary to explain the legal value of mediation from the view of jurisprudence.
A two‐step photocatalytic water splitting system,termed a“Z‐scheme system”,was achieved using Zn‐doped g‐C3N4for H2evolution and BiVO4for O2evolution with Fe2+/Fe3+as a shuttle redox mediator.H2and O2were evalua...A two‐step photocatalytic water splitting system,termed a“Z‐scheme system”,was achieved using Zn‐doped g‐C3N4for H2evolution and BiVO4for O2evolution with Fe2+/Fe3+as a shuttle redox mediator.H2and O2were evaluated simultaneously when the doping amount of zinc was10%.Moreover,Zn‐doped(10%)g‐C3N4synthesized by an impregnation method showed superior active ability to form the Z‐scheme with BiVO4than by in‐situ synthesis.X‐ray diffraction,UV‐Vis spectroscopy,scanning electron microscopy,and X‐ray photoelectron spectroscopy were used to characterize the samples.It was determined that more Zn?N bonds could be formed on the surface of g‐C3N4by impregnation,which could facilitate charge transfer.展开更多
As promising anodes for sodium-ion batteries,metal sulfides ubiquitously suffer from low-rate and high-plateau issues,greatly hindering their application in full-cells.Herein,exemplifying carbon nanotubes(CNTs)-string...As promising anodes for sodium-ion batteries,metal sulfides ubiquitously suffer from low-rate and high-plateau issues,greatly hindering their application in full-cells.Herein,exemplifying carbon nanotubes(CNTs)-stringed metal sulfides superstructure(CSC)assembled by nano-dispersed SnS_(2) and CoS_(2) phases,cocktail mediation effect similar to that of high-entropy materials is initially studied in ether-based electrolyte to solve the challenges.The high nano-dispersity of metal sulfides in CSC anode underlies the cocktail-like mediation effect,enabling the circumvention of intrinsic drawbacks of different metal sulfides.By utilizing ether-based electrolyte,the reversibility of metal sulfides is greatly improved,sustaining a long-life effectivity of cocktail-like mediation.As such,CSC effectively overcomes low-rate flaw of SnS_(2) and highplateau demerit of CoS_(2),simultaneously realizes a high rate and a low plateau.In half-cells,CSC delivers an ultrahigh-rate capability of 327.6 mAh g^(−1) anode at 20 A g^(−1),far outperforming those of monometallic sulfides(SnS_(2),CoS_(2))and their mixtures.Compared with CoS_(2) phase and SnS_(2)/CoS_(2) mixture,CSC shows remarkably lowered average charge voltage up to ca.0.62 V.As-assembled CSC//Na1.5VPO4.8F0.7 full-cell shows a good rate capability(0.05~1.0 A g^(−1),120.3 mAh g^(−1) electrode at 0.05 A g^(−1))and a high average discharge voltage up to 2.57 V,comparable to full-cells with alloy-type anodes.Kinetics analysis verifies that the cocktail-like mediation effect largely boosts the charge transfer and ionic diffusion in CSC,compared with single phase and mixed phases.Further mechanism study reveals that alternative and complementary electrochemical processes between nano-dispersed SnS_(2) and CoS_(2) phases are responsible for the lowered charge voltage of CSC.This electrolyte/structure-dependent cocktail-like mediation effect effectively enhances the practicability of metal sulfide anodes,which will boost the development of high-rate/-voltage sodium-ion full batteries.展开更多
Objective:This study aimed to identify the mediation effects of health locus of control(HLC)and hope between stroke patients’social support and self-management.Methods:A cross-sectional study was conducted.A total of...Objective:This study aimed to identify the mediation effects of health locus of control(HLC)and hope between stroke patients’social support and self-management.Methods:A cross-sectional study was conducted.A total of 300 Chinese stroke patients were recruited by convenient sampling from the acupuncture department of two Chinese Traditional Medical Hospitals in Tianjin Province from June to September 2018.The self-report questionnaires include Social Support Assessment Scale,Herth Hope Index,Mental Health Locus of Control Scale,Stroke Self-management Behavior Scale,and personal information questionnaires.All the survey data were entered in Excel and analyzed using the SPSS 24.0 program.Mediation was tested with Bootstrapping in AMOS 23.0 program.Results:The result showed that internal health locus of control(IHLC),chance health locus of control(CHLC)and hope were the mediators between social support and self-management.The direct,indirect,and total effects of social support on self-management behavior were 0.306 (P<0.01),0.109(P<0.01),and 0.415(P<0.01),respectively.Conclusions:Social support can directly influence self-management,and it can also indirectly influence self-management through IHLC,CHLC,and hope.展开更多
BACKGROUND Existing literature suggests a positive link between childhood maltreatment(CM)and suicide ideation(SI).Nevertheless,whether social support significantly mediates this association remains unknown.AIM To inv...BACKGROUND Existing literature suggests a positive link between childhood maltreatment(CM)and suicide ideation(SI).Nevertheless,whether social support significantly mediates this association remains unknown.AIM To investigate whether social support significantly mediates the association between CM and SI.METHODS In this cross-sectional study of 4732 adolescents from southwest China,we intended to discuss the association between CM and multiple types of SI.In addition,the mediation of major types of social support in this association was also investigated.A self-administrated questionnaire was used to collect the data.A series of multivariate logistic regression models were employed to estimate the association between different types of CM,social support,and SI.The possible mediation of social support in the association between CM and SI was assessed using the path model.RESULTS Based on the cutoffs for subscales of Childhood Trauma Questionnaire,928(19.61%),1269(26.82%),595(12.57%),2337(49.39%),and 3067(64.81%)respondents reported physical abuse,emotional abuse,sexual abuse,physical neglect,and emotional neglect,respectively.Among all the social sources,parental support presented as a significant mediator in the association between emotional maltreatment,both abuse and neglect,and all three types of SI:1-wk,1-year,and lifetime.Parental social support mediated 5.31%and 29.23%,4.80%and 24.50%,and 7.04%and 44.42%of the overall emotional abuse-SI and emotional neglect-SI associations,respectively.CONCLUSION Our findings suggest that improving parental social support might be effective in preventing suicidal risk related to childhood emotional maltreatment in adolescents.展开更多
In this research study, we have synthesized the bio-capped ZnO/g-C_(3)N_(4) nanocomposites by employing lemon juice(Citrus limon) as a stabilizer and mediator. Fruitfully, lemon juice which contains various acidic fun...In this research study, we have synthesized the bio-capped ZnO/g-C_(3)N_(4) nanocomposites by employing lemon juice(Citrus limon) as a stabilizer and mediator. Fruitfully, lemon juice which contains various acidic functional groups and citric acid has the capability to block the surface of g-C_(3)N_(4) from chemical reactivity and activated the surface of g-C_(3)N_(4) for various reactions. Consequently, the agglomeration behavior and controlled shape of g-C_(3)N_(4) has also been achieved. Our experimental results i.e. XRD,TEM, HRTEM, PL, FS, XPS, and PEC have confirmed that the lemon juice mediated and green g-C_(3)N_(4)(L-CN) have good performances and remarkable visible light photocatalytic activities as compared to the chemically synthesized g-C_(3)N_(4)(CN). Furthermore, the small surface area and low charge separation of g-C_(3)N_(4) is upgraded by coupling with Zn O nanoparticles. It is proved that the coupling of Zn O worked as a facilitator and photoelectron modulator to enhance the charge separation of g-C_(3)N_(4). Compared to pristine lemon-mediated green g-C_(3)N_(4)(L-CN), the most active sample 5Zn O/L-CN showed ~ 5-fold improvement in activities for ciprofloxacin(CIP) and methylene blue(MB) degradation. More specifically,the mineralization process and degradation pathways, and the mineralization process of ciprofloxacin(CIP) and methylene blue(MB) are suggested. Finally, our present novel research work will provide new access to synthesize the eco-friendly and bio-caped green g-C_(3)N_(4)nanomaterials and their employment for pollutants degradation and environmental purification.展开更多
Aging is well known to be the main risk factor for the neurodegenerative pathologies,in particular,Parkinson’s disease(PD)and Alzheimer’s disease(AD).In aging and in the diseases,similar changes in various hallm...Aging is well known to be the main risk factor for the neurodegenerative pathologies,in particular,Parkinson’s disease(PD)and Alzheimer’s disease(AD).In aging and in the diseases,similar changes in various hallmarks of neurodegeneration(lipofuscin accumulation,autophagia weakening,and disturbances in functions of mitochondriaand lysosomes) were shown (Tan et al., 2014). Furthermore, dopami- nergic system (DAS) involvement in mechanisms of aging, PD, and AD were revealed (Martorana and Koch, 2014).展开更多
We have developed a wearable system for mobile distributed collaboration called HandsInAir using emerging wireless and mobile technologies. This system was developed to support real world scenarios in which a remote m...We have developed a wearable system for mobile distributed collaboration called HandsInAir using emerging wireless and mobile technologies. This system was developed to support real world scenarios in which a remote mobile helper guides a local mobile worker in the completion of a physical task. HandsInAir consists of a helper unit and a worker unit. Both units are equipped with wearable devices having the same hardware configuration, but running different pieces of software to support the distinct roles of the collaborators (helper and worker). The two sides are connected via a wireless network and the collaboration partners can communicate with each other via audio and visual links. In this paper we describe the technical implementation of the system and present a preliminary evaluation of it. The paper concludes with a brief discussion of possible future work for further improvements and new developments.展开更多
With the increasing cross-cultural exchanges,the translator should respect and spread the source culture.It is necessary for translators to employ as much as possible the foreignizing translation to keep the exotic fl...With the increasing cross-cultural exchanges,the translator should respect and spread the source culture.It is necessary for translators to employ as much as possible the foreignizing translation to keep the exotic flavor of the source language.A Chinese translator’s responsibility is to spread Chinese culture.展开更多
基金financed by the French government IDEX-ISITE initiative 16-IDEX-0001(CAP 20-25)the PhD is funded by the European Regional Development Fund(FEDER).
文摘Recent advances in big and streaming data systems have enabled real-time analysis of data generated by Internet of Things(IoT)systems and sensors in various domains.In this context,many applications require integrating data from several heterogeneous sources,either stream or static sources.Frameworks such as Apache Spark are able to integrate and process large datasets from different sources.However,these frameworks are hard to use when the data sources are heterogeneous and numerous.To address this issue,we propose a system based on mediation techniques for integrating stream and static data sources.The integration process of our system consists of three main steps:configuration,query expression and query execution.In the configuration step,an administrator designs a mediated schema and defines mapping between the mediated schema and local data sources.In the query expression step,users express queries using customized SQL grammar on the mediated schema.Finally,our system rewrites the query into an optimized Spark application and submits the application to a Spark cluster.The results are continuously returned to users.Our experiments show that our optimizations can improve query execution time by up to one order of magnitude,making complex streaming and spatial data analysis more accessible.
基金Supported by the Shijiazhuang Science and Technology Research and Development Program,No.221460383.
文摘BACKGROUND Emotional reactions,such as anxiety,irritability,and aggressive behavior,have attracted clinical attention as behavioral and emotional problems in preschool-age children.AIM To investigate the current status of family rearing,parental stress,and behavioral and emotional problems of preschool children and to analyze the mediating effect of the current status of family rearing on parental stress and behavioral/emo-tional problems.METHODS We use convenience sampling to select 258 preschool children in the physical examination center of our hospital from October 2021 to September 2023.The children and their parents were evaluated using a questionnaire survey.Pearson's correlation was used to analyze the correlation between child behavioral and emotional problems and parental stress and family rearing,and the structural equation model was constructed to test the mediating effect.RESULTS The score for behavioral/emotional problems of 258 preschool children was(27.54±3.63),the score for parental stress was(87.64±11.34),and the score for parental family rearing was(31.54±5.24).There was a positive correlation between the behavioral and emotional problems of the children and the“hostile/mandatory”parenting style;meanwhile,showed a negative correlation with the“support/participation”parenting style(all P<0.05).The intermediary effect value between the family upbringing of parents in parental stress and children's behavior problems was 29.89%.CONCLUSION Parental family upbringing has a mediating effect between parental stress and behavioral and emotional problems of children.Despite paying attention to the behavioral and emotional problems of preschool-age children,clinical medical staff should provide correct and reasonable parenting advice to their parents to promote the mental health of preschool-age children.
基金Supported by City Science and Technology Development Project in Jining,No.2021YXNS049,No.2022YXNS100,No.2022YXNS102,and No.2022YXNS109。
文摘BACKGROUND Depression is a prevalent psychological issue in adolescents that is significantly related to negative life events(NLEs)and dysfunctional attitudes.High levels of social support can significantly buffer NLEs’effect on depression.Currently,there is limited research on how social support moderates the relationship between NLEs,dysfunctional attitudes,and depression in adolescents in China.It is imperative to investigate this moderating effect to mitigate dysfunctional attitudes in adolescent undergoing depressive mood,ultimately enhancing their overall mental health.AIM To investigate the relationship and underlying mechanisms between specific dysfunctional attitudes,social support,and depression among Chinese adolescents.METHODS This is a cross-sectional study which selected five middle schools in Shandong Province for investigation in March 2022.Participants included 795 adolescents(49.87%male,mage=15.15,SD=1.84,age range=11-18 years old).All participants completed the Dysfunctional Attitude Scale,Adolescent Life Event Scale,Beck Depression Inventory,and Social Support Rating Scale.A moderated mediation model was conducted to examine the relationship between specific dysfunctional attitudes,social support,and depression.RESULTS Results indicated that NLEs affected depression through the mediating role of specific dysfunctional attitudes(autonomy attitudesβ=0.21;perfectionismβ=0.25).Moreover,social support was found to moderate the mediating effect between NLEs,specific dysfunctional attitudes,and depressive symptoms(autonomy attitudes b2=-0.08;perfectionism b2=-0.09).CONCLUSION Dysfunctional attitudes mediated and social support moderated the relationship between NLEs and depression.Social support can buffer depression symptoms among adolescents with autonomy attitudes and perfectionism.
基金This study is supported by the National Key Research and Development Program of China(2017YFB0307500).
文摘Implementing a new energy-saving electrochemical synthesis system with high commercial value is a strategy of the sustainable development for upgrading the bulk chemicals preparation technology in the future.Here,we report a multiple redox-mediated linear paired electrolysis system,combining the hydrogen peroxide mediated cathode process with the I2 mediated anode process,and realize the conversion of furfural to furoic acid in both side of the dividedflow cell simultaneously.By reasonably controlling the cathode potential,the undesired water splitting reaction and furfural reduction side reactions are avoided.Under the galvanostatic electrolysis,the two-mediated electrode processes have good compatibility,which reduce the energy consumption by about 22%while improving the electronic efficiency by about 125%.This system provides a green electrochemical synthesis route with commercial prospects.
基金funded by Asia-Pacific Observatory on Health Systems and Policies(APO).
文摘Background:In addition to healthcare entitlements,‘migrant-friendly health services’in Thailand include interpretation and cultural mediation services which aim to reduce language and cultural barriers between health personnel and migrants.Although the Thai Government started implementing these services in 2003,challenges in providing them still remain.This study aims to analyse the health system functions which support the interpretation and cultural mediation services of migrant health worker(MHW)and migrant health volunteer(MHV)programmes in Thailand.Methods:In-depth interviews were conducted in two migrant-populated provinces using purposive and snowball sampling.A total of fifty key informants were recruited,including MHWs,MHVs,health professionals,non-governmental organisation(NGO)staff and policy stakeholders.Data were triangulated using information from policy documents.The deductive thematic analysis was classified into three main themes of evolving structure of MHW and MHV programmes,roles and responsibilities of MHWs and MHVs,and supporting systems.Results:The introduction of the MHW and MHV programmes was one of the most prominent steps taken to improve the migrant-friendliness of Thai health services.MHWs mainly served as interpreters in public facilities,while MHVs served as cultural mediators in migrant communities.Operational challenges in providing services included insufficient budgets for employment and training,diverse training curricula,and lack of legal provisions to sustain the MHW and MHV programmes.Conclusion:Interpretation and cultural mediation services are hugely beneficial in addressing the health needs of migrants.To ensure the sustainability of current service provision,clear policy regulation and standardised training courses should be in place,alongside adequate and sustainable financial support from central government,NGOs,employers and migrant workers themselves.Moreover,regular monitoring and evaluation of the quality of services are recommended.Finally,a lead agency should be mandated to collaborate with stakeholders in planning the overall structure and resource allocation for the programmes.
基金funded by the Humanities and Social Sciences Foundation of the Ministry of Education(23JDSZ3163)the 2023 Project of the“14th Five-Year Plan”for Education Science of Shandong Province and the Achievements of the Famous Tutors’Workshop in Shandong Province(202405).
文摘Background:College students face significant academic and physiological changes,making them more susceptible to psychological issues such as depression,self-injury,and suicidal ideation.Feelings of defeat can exacerbate these risks by increasing academic stress.However,interpersonal relationships can moderate the impact of academic stress on students’mental health.Utilizing the presage–process–product model,this study aims to empirically investigate how feelings of defeat influence depression,self-injury,and suicidal ideation among college students.Additionally,it explores the mediating role of academic stress and the moderating role of various types of interpersonal relationships.Methods:A total of 1612 college students(750 females,862 males,mean age=19.64±0.62 years)were recruited through cluster sampling.Data were collected via offline questionnaires administered by a trained psychology teacher and a postgraduate student,ensuring high reliability with two examiners per class.Latent profile analysis(LPA)was used to examine the impact of defeat on mental health outcomes,while mediation analysis was conducted to assess the roles of academic stress and interpersonal relationships.Results:1.Defeat is identified as a significant risk factor for mental health issues among college students;2.Four distinct patterns of interpersonal relationships were identified:the interpersonal-relationship risk group,the father–child-relationship high-risk group,the general interpersonal-relationship group,and the superior interpersonal-relationship group;3.Academic stress partially mediates the relationship between defeat and mental health issues such as depression,self-injury,and suicidal ideation;4.Different interpersonal relationship models moderate the impact of academic stress on depression and suicidal ideation.Conclusion:Defeat is a significant risk factor for mental health problems in college students.Academic stress partially mediates the negative impact of defeat on mental health,while patterns of interpersonal relationships moderate this impact.Effective early prevention and intervention should focus on monitoring students’stress levels and fostering warm,positive parent–child relationships.
基金supported by the National Social Science Foundation of China(20BSH131).
文摘Internet gaming disorder(IGD)among junior high school students is an increasingly prominent mental health concern.It is important to look for influences behind internet gaming disorder tendency(IGDT)in the junior high school student population.The present study aimed to reveal the explanatory mechanisms underlying the association between parental psychological control(PPC)and internet gaming disorder tendency among junior high school students by testing the mediating role of core self-evaluation(CSE)and the moderating role of intentional self-regulation(ISR).Participants in present study were 735 Chinese junior high school students who completed offline self-report questionnaires on parental psychological control,core self-evaluation,intentional self-regulation,and Internet gaming disorder tendency.Analyses were conducted via mediation and moderated mediation.The results showed that:(1)Parental psychological control was positively related to junior high school students’Internet gaming disorder tendency.Core self-evaluation,and intentional self-regulation were negatively related to junior high school students’Internet gaming disorder tendency,respectively.(2)Core self-evaluation partially mediated the relationship between parental psychological control and junior high school students’Internet gaming disorder tendency.(3)Intentional self-regulation moderated the association between parental psychological control and Internet gaming disorder tendency,as well as the relationships between parental psychological control and core self-evaluation and core self-evaluation and Internet gaming disorder tendency in the mediated model.Based on these findings,we believe that there is a need to weaken parental psychological control,strengthen junior high school students’core self-evaluation and intentional self-regulation,and to recognize the important role of parents as well as their children’s personal positive traits in the healthy development of junior high school students.
文摘Colorectal cancer(CRC)poses significant physical and psychological challenges that necessitate an exploration of factors influencing post-traumatic growth(PTG)for patient well-being.This study aims to investigate the effects of positive psychological capital(PsyCap)and perceived stress on mediating the social support-PTG relation among 673 CRC patients.Social support,positive PsyCap,perceived stress,and PTG were assessed through questionnaires.The results indicated a direct prediction effect of social support on PTG(LICI=0.481,ULCI=0.644),with the direct effect being 59.5%.Both positive PsyCap and perceived stress exerted a mediating role in the correlation between social support and PTG,with the mediating effects occupying 29.4%(LICI=0.217,ULCI=0.343)and 5.7%(LICI=0.030,ULCI=0.082),respectively.Positive PsyCap further had a chain mediating effect on perceived stress(LICI=0.031,ULCI=0.074),with the chain effect accounting for 5.4%.The total impact of social support on PTG was 100%(LICI=0.882,ULCI=1.008).This model underscores the pivotal role of social support in promoting PTG in CRC patients.Positive PsyCap serves as a crucial mediator in the social support-PTG link,with perceived stress playing a sequential mediating role.Thesefindings suggest that strengthening social support networks and cultivating positive PsyCap may reduce perceived stress and promote the development of PTG in CRC patients.Consequently,intervention programs are recommended to improve the psychosocial well-being of CRC patients.
文摘With the rise of new media and short videos shaping the new communication environment,rural culture has been mediated and transformed to spread to a wider region.As a cultural achievement of rural revitalization,“Village BA”(Village Basketball Association)demonstrates Chinese modernization.The use of short videos,mass rural movements,and“spectacle”spaces to attract spectators has become a key issue in the dissemination of rural culture.
基金supported by the China Scholarship Council(to YW)the Swedish Research Council,No.2018-02601(to MS)+7 种基金the Alzheimer Foundation,No.AF-980695(to MS)the Stockholm County Council,No.RS2020-0731(to MS)the Foundation of Old Servants(to MS)the Gun and Bertil Stohne Foundation(to MS)the?hlén Foundation,No.233055(to MS)The Swedish Fund for Research without Animal Experiments(to MS)the Swedish Dementia Foundation(to MS)the Brain foundation,No.FO2022-0131(to MS)。
文摘Specialized pro-resolving lipid mediators including maresin 1 mediate resolution but the levels of these are reduced in Alzheimer's disease brain, suggesting that they constitute a novel target for the treatment of Alzheimer's disease to prevent/stop inflammation and combat disease pathology. Therefore, it is important to clarify whether they counteract the expression of genes and proteins induced by amyloid-β. With this objective, we analyzed the relevance of human monocyte–derived microglia for in vitro modeling of neuroinflammation and its resolution in the context of Alzheimer's disease and investigated the pro-resolving bioactivity of maresin 1 on amyloid-β42–induced Alzheimer's disease–like inflammation. Analysis of RNA-sequencing data and secreted proteins in supernatants from the monocyte-derived microglia showed that the monocyte-derived microglia resembled Alzheimer's disease–like neuroinflammation in human brain microglia after incubation with amyloid-β42. Maresin 1 restored homeostasis by down-regulating inflammatory pathway related gene expression induced by amyloid-β42 in monocyte-derived microglia, protection of maresin 1 against the effects of amyloid-β42 is mediated by a re-balancing of inflammatory transcriptional networks in which modulation of gene transcription in the nuclear factor-kappa B pathway plays a major part. We pinpointed molecular targets that are associated with both neuroinflammation in Alzheimer's disease and therapeutic targets by maresin 1. In conclusion, monocyte-derived microglia represent a relevant in vitro microglial model for studies on Alzheimer's disease-like inflammation and drug response for individual patients. Maresin 1 ameliorates amyloid-β42–induced changes in several genes of importance in Alzheimer's disease, highlighting its potential as a therapeutic target for Alzheimer's disease.
文摘Mediation is becoming more and more important in the process of settling conflict nowadays,so it’s quite necessary to explain the legal value of mediation from the view of jurisprudence.
基金supported by the National Natural Science Foundation of China (21773153)~~
文摘A two‐step photocatalytic water splitting system,termed a“Z‐scheme system”,was achieved using Zn‐doped g‐C3N4for H2evolution and BiVO4for O2evolution with Fe2+/Fe3+as a shuttle redox mediator.H2and O2were evaluated simultaneously when the doping amount of zinc was10%.Moreover,Zn‐doped(10%)g‐C3N4synthesized by an impregnation method showed superior active ability to form the Z‐scheme with BiVO4than by in‐situ synthesis.X‐ray diffraction,UV‐Vis spectroscopy,scanning electron microscopy,and X‐ray photoelectron spectroscopy were used to characterize the samples.It was determined that more Zn?N bonds could be formed on the surface of g‐C3N4by impregnation,which could facilitate charge transfer.
基金This work was supported by Guangdong Basic and Applied Basic Research Foundation,China(No.2019A1515110980)research project from the National Natural Science Foundation of China(No.21361162004)China Scholarship Council,and CSIRO.We acknowledge Dr Yesim Gozukara,Dr Malisja de Vries,and Dr Yunxia Yang from CSIRO(Clayton)for their help with material characterization training.
文摘As promising anodes for sodium-ion batteries,metal sulfides ubiquitously suffer from low-rate and high-plateau issues,greatly hindering their application in full-cells.Herein,exemplifying carbon nanotubes(CNTs)-stringed metal sulfides superstructure(CSC)assembled by nano-dispersed SnS_(2) and CoS_(2) phases,cocktail mediation effect similar to that of high-entropy materials is initially studied in ether-based electrolyte to solve the challenges.The high nano-dispersity of metal sulfides in CSC anode underlies the cocktail-like mediation effect,enabling the circumvention of intrinsic drawbacks of different metal sulfides.By utilizing ether-based electrolyte,the reversibility of metal sulfides is greatly improved,sustaining a long-life effectivity of cocktail-like mediation.As such,CSC effectively overcomes low-rate flaw of SnS_(2) and highplateau demerit of CoS_(2),simultaneously realizes a high rate and a low plateau.In half-cells,CSC delivers an ultrahigh-rate capability of 327.6 mAh g^(−1) anode at 20 A g^(−1),far outperforming those of monometallic sulfides(SnS_(2),CoS_(2))and their mixtures.Compared with CoS_(2) phase and SnS_(2)/CoS_(2) mixture,CSC shows remarkably lowered average charge voltage up to ca.0.62 V.As-assembled CSC//Na1.5VPO4.8F0.7 full-cell shows a good rate capability(0.05~1.0 A g^(−1),120.3 mAh g^(−1) electrode at 0.05 A g^(−1))and a high average discharge voltage up to 2.57 V,comparable to full-cells with alloy-type anodes.Kinetics analysis verifies that the cocktail-like mediation effect largely boosts the charge transfer and ionic diffusion in CSC,compared with single phase and mixed phases.Further mechanism study reveals that alternative and complementary electrochemical processes between nano-dispersed SnS_(2) and CoS_(2) phases are responsible for the lowered charge voltage of CSC.This electrolyte/structure-dependent cocktail-like mediation effect effectively enhances the practicability of metal sulfide anodes,which will boost the development of high-rate/-voltage sodium-ion full batteries.
文摘Objective:This study aimed to identify the mediation effects of health locus of control(HLC)and hope between stroke patients’social support and self-management.Methods:A cross-sectional study was conducted.A total of 300 Chinese stroke patients were recruited by convenient sampling from the acupuncture department of two Chinese Traditional Medical Hospitals in Tianjin Province from June to September 2018.The self-report questionnaires include Social Support Assessment Scale,Herth Hope Index,Mental Health Locus of Control Scale,Stroke Self-management Behavior Scale,and personal information questionnaires.All the survey data were entered in Excel and analyzed using the SPSS 24.0 program.Mediation was tested with Bootstrapping in AMOS 23.0 program.Results:The result showed that internal health locus of control(IHLC),chance health locus of control(CHLC)and hope were the mediators between social support and self-management.The direct,indirect,and total effects of social support on self-management behavior were 0.306 (P<0.01),0.109(P<0.01),and 0.415(P<0.01),respectively.Conclusions:Social support can directly influence self-management,and it can also indirectly influence self-management through IHLC,CHLC,and hope.
基金Supported by the National Natural Science Foundation of China,No. 82060601Top Young Talents of Yunnan Ten Thousand Talents Plan,No. YNWR-QNBJ-2018-286Innovative Research Team of Yunnan Province,No. 202005AE160002
文摘BACKGROUND Existing literature suggests a positive link between childhood maltreatment(CM)and suicide ideation(SI).Nevertheless,whether social support significantly mediates this association remains unknown.AIM To investigate whether social support significantly mediates the association between CM and SI.METHODS In this cross-sectional study of 4732 adolescents from southwest China,we intended to discuss the association between CM and multiple types of SI.In addition,the mediation of major types of social support in this association was also investigated.A self-administrated questionnaire was used to collect the data.A series of multivariate logistic regression models were employed to estimate the association between different types of CM,social support,and SI.The possible mediation of social support in the association between CM and SI was assessed using the path model.RESULTS Based on the cutoffs for subscales of Childhood Trauma Questionnaire,928(19.61%),1269(26.82%),595(12.57%),2337(49.39%),and 3067(64.81%)respondents reported physical abuse,emotional abuse,sexual abuse,physical neglect,and emotional neglect,respectively.Among all the social sources,parental support presented as a significant mediator in the association between emotional maltreatment,both abuse and neglect,and all three types of SI:1-wk,1-year,and lifetime.Parental social support mediated 5.31%and 29.23%,4.80%and 24.50%,and 7.04%and 44.42%of the overall emotional abuse-SI and emotional neglect-SI associations,respectively.CONCLUSION Our findings suggest that improving parental social support might be effective in preventing suicidal risk related to childhood emotional maltreatment in adolescents.
基金Jiangsu University of Science and Technology for providing financial support under the Research start-up fund for the introduction of young talent at Jiangsu University of Science and Technology (Grant no. 1112932205)High-level Talents Program of Shihezi University (RCZK2021B25)。
文摘In this research study, we have synthesized the bio-capped ZnO/g-C_(3)N_(4) nanocomposites by employing lemon juice(Citrus limon) as a stabilizer and mediator. Fruitfully, lemon juice which contains various acidic functional groups and citric acid has the capability to block the surface of g-C_(3)N_(4) from chemical reactivity and activated the surface of g-C_(3)N_(4) for various reactions. Consequently, the agglomeration behavior and controlled shape of g-C_(3)N_(4) has also been achieved. Our experimental results i.e. XRD,TEM, HRTEM, PL, FS, XPS, and PEC have confirmed that the lemon juice mediated and green g-C_(3)N_(4)(L-CN) have good performances and remarkable visible light photocatalytic activities as compared to the chemically synthesized g-C_(3)N_(4)(CN). Furthermore, the small surface area and low charge separation of g-C_(3)N_(4) is upgraded by coupling with Zn O nanoparticles. It is proved that the coupling of Zn O worked as a facilitator and photoelectron modulator to enhance the charge separation of g-C_(3)N_(4). Compared to pristine lemon-mediated green g-C_(3)N_(4)(L-CN), the most active sample 5Zn O/L-CN showed ~ 5-fold improvement in activities for ciprofloxacin(CIP) and methylene blue(MB) degradation. More specifically,the mineralization process and degradation pathways, and the mineralization process of ciprofloxacin(CIP) and methylene blue(MB) are suggested. Finally, our present novel research work will provide new access to synthesize the eco-friendly and bio-caped green g-C_(3)N_(4)nanomaterials and their employment for pollutants degradation and environmental purification.
文摘Aging is well known to be the main risk factor for the neurodegenerative pathologies,in particular,Parkinson’s disease(PD)and Alzheimer’s disease(AD).In aging and in the diseases,similar changes in various hallmarks of neurodegeneration(lipofuscin accumulation,autophagia weakening,and disturbances in functions of mitochondriaand lysosomes) were shown (Tan et al., 2014). Furthermore, dopami- nergic system (DAS) involvement in mechanisms of aging, PD, and AD were revealed (Martorana and Koch, 2014).
文摘We have developed a wearable system for mobile distributed collaboration called HandsInAir using emerging wireless and mobile technologies. This system was developed to support real world scenarios in which a remote mobile helper guides a local mobile worker in the completion of a physical task. HandsInAir consists of a helper unit and a worker unit. Both units are equipped with wearable devices having the same hardware configuration, but running different pieces of software to support the distinct roles of the collaborators (helper and worker). The two sides are connected via a wireless network and the collaboration partners can communicate with each other via audio and visual links. In this paper we describe the technical implementation of the system and present a preliminary evaluation of it. The paper concludes with a brief discussion of possible future work for further improvements and new developments.
文摘With the increasing cross-cultural exchanges,the translator should respect and spread the source culture.It is necessary for translators to employ as much as possible the foreignizing translation to keep the exotic flavor of the source language.A Chinese translator’s responsibility is to spread Chinese culture.