A new method for recharging active medical implant(AMI)in vitro based on incoherent light source and results of the simulation experiments are proposed.Firstly,the models of the AMI recharging method based on incohe...A new method for recharging active medical implant(AMI)in vitro based on incoherent light source and results of the simulation experiments are proposed.Firstly,the models of the AMI recharging method based on incoherent light source in vitro are developed,which include the models of an incoherent light source and skin tissue.Secondly,simulation experiments of the incoherent light source of the AMI recharging process in vitro based on the Monte Carlo(MC)method are carried out.Finally,absorbed fractions of different layers and distributions of density along x axis of the tissue model and other important conclusions have been achieved.展开更多
Atorvastatin, a lipid-lowering medication, provides neuroprotective effects, although the precise mechanisms of action remain unclear. Our previous studies confirmed activated autophagy following spinal cord injury, w...Atorvastatin, a lipid-lowering medication, provides neuroprotective effects, although the precise mechanisms of action remain unclear. Our previous studies confirmed activated autophagy following spinal cord injury, which was conducive to recovery of neurological functions. We hypothesized that atorvastatin could also activate autophagy after spinal cord injury, and subsequently improve recovery of neurological functions. A rat model of spinal cord injury was established based on the Allen method. Atorvastatin(5 mg/kg) was intraperitoneally injected at 1 and 2 days after spinal cord injury. At 7 days post-injury, western blot assay, reverse transcription-polymerase chain reaction, and terminal deoxynucleotidyl transferase-mediated dU TP nick-end labeling(TUNEL) staining results showed increased Beclin-1 and light chain 3B gene and protein expressions in the spinal cord injury + atorvastatin group. Additionally, caspase-9 and caspase-3 expression was decreased, and the number of TUNEL-positive cells was reduced. Compared with the spinal cord injury + saline group, Basso, Beattie, and Bresnahan locomotor rating scale scores significantly increased in the spinal cord injury + atorvastatin group at 14–42 days post-injury. These findings suggest that atorvastatin activated autophagy after spinal cord injury, inhibited apoptosis, and promoted recovery of neurological function.展开更多
Qigong(气功)therapy is an active self-paced exercise therapy and it has a long history in traditional Chinese medicine(TCM).As early as the mention of it in the Huang Di Nei Jing(《黄帝内经》Huangdi s Internal Classic...Qigong(气功)therapy is an active self-paced exercise therapy and it has a long history in traditional Chinese medicine(TCM).As early as the mention of it in the Huang Di Nei Jing(《黄帝内经》Huangdi s Internal Classic),there is a record of using qigong therapy to prevent and treat pestilence.This thesis discusses the idea and methods of qigong therapy in TCM,such as daoyin(导引),expiration and inspiration,and meditation.These methods purpose to have the functions of strengthening and consolidating the primordial qi,improving health conditions,and resisting pestilent qi.Therefore,the core idea of fighting the epidemic with qigong therapy is to enhance the healthy qi,and to prevent the intrusion of pestilent qi into the human body.It embodies the TCM thought of“when there is sufficient healthy qi inside the body,the evil cannot invade the body.”展开更多
基金Supported by the Excellent Young Scholars Research Fund of Beijing Institute of Technology(3040012211310)the Basic Research Fund of Beijing Institute of Technology(20120442010)
文摘A new method for recharging active medical implant(AMI)in vitro based on incoherent light source and results of the simulation experiments are proposed.Firstly,the models of the AMI recharging method based on incoherent light source in vitro are developed,which include the models of an incoherent light source and skin tissue.Secondly,simulation experiments of the incoherent light source of the AMI recharging process in vitro based on the Monte Carlo(MC)method are carried out.Finally,absorbed fractions of different layers and distributions of density along x axis of the tissue model and other important conclusions have been achieved.
基金supported by the National Natural Science Foundation of China,No.81471854
文摘Atorvastatin, a lipid-lowering medication, provides neuroprotective effects, although the precise mechanisms of action remain unclear. Our previous studies confirmed activated autophagy following spinal cord injury, which was conducive to recovery of neurological functions. We hypothesized that atorvastatin could also activate autophagy after spinal cord injury, and subsequently improve recovery of neurological functions. A rat model of spinal cord injury was established based on the Allen method. Atorvastatin(5 mg/kg) was intraperitoneally injected at 1 and 2 days after spinal cord injury. At 7 days post-injury, western blot assay, reverse transcription-polymerase chain reaction, and terminal deoxynucleotidyl transferase-mediated dU TP nick-end labeling(TUNEL) staining results showed increased Beclin-1 and light chain 3B gene and protein expressions in the spinal cord injury + atorvastatin group. Additionally, caspase-9 and caspase-3 expression was decreased, and the number of TUNEL-positive cells was reduced. Compared with the spinal cord injury + saline group, Basso, Beattie, and Bresnahan locomotor rating scale scores significantly increased in the spinal cord injury + atorvastatin group at 14–42 days post-injury. These findings suggest that atorvastatin activated autophagy after spinal cord injury, inhibited apoptosis, and promoted recovery of neurological function.
基金By grants from the Youth Fund for Humanities and Social Sciences of Ministry of Education(No.20 YJCZH240)“Taiji Health”platform development of 3-year action plan for Shanghai to further accelerate the development of TCM Career(No.ZY(2018-2020)-CCCX-2007).
文摘Qigong(气功)therapy is an active self-paced exercise therapy and it has a long history in traditional Chinese medicine(TCM).As early as the mention of it in the Huang Di Nei Jing(《黄帝内经》Huangdi s Internal Classic),there is a record of using qigong therapy to prevent and treat pestilence.This thesis discusses the idea and methods of qigong therapy in TCM,such as daoyin(导引),expiration and inspiration,and meditation.These methods purpose to have the functions of strengthening and consolidating the primordial qi,improving health conditions,and resisting pestilent qi.Therefore,the core idea of fighting the epidemic with qigong therapy is to enhance the healthy qi,and to prevent the intrusion of pestilent qi into the human body.It embodies the TCM thought of“when there is sufficient healthy qi inside the body,the evil cannot invade the body.”