AIM： To describe the imaging features of hepatic mesenchymal hamartoma with emphasis on magnetic resonance imaging （MRI） compared to histopathologic results. METHODS： Spin-echo sequence（SE）,fast spin-echo seque...AIM： To describe the imaging features of hepatic mesenchymal hamartoma with emphasis on magnetic resonance imaging （MRI） compared to histopathologic results. METHODS： Spin-echo sequence（SE）,fast spin-echo sequence（FSE） were detected in 12 children （7 males,5 females） with mesenchymal hamartoma of the liver （IVlHL）, aged 1.2 months to 12 years,（ mean age, 6.3 years） by axial, saggital, coronary plain imaging with an Elscint 2.0T MR equipment. Their main symptoms were abdominal mass （5 cases）, enlarged liver （8 cases）, abdominal pain （1 case） and anemia （2 cases）, and negative alpha-fetoprotein. Dynamic enhancement examination was added in 2 cases. RESULTS： Six cases had single mass type of MHL, in which 3 cases had solid masses showing slight low- signal-intensity in TlWI, and irregular high-signal- intensity in T2WI, 1 case had a cystic-solid mixed mass showing several border-clear cysts in a solid mass, 2 cases had cystic masses with multi-septa. Five cases had diffuse and multifocal lesions type of MHL with its signal intensity being similar to that of the solid mass. One case had a combined diffuse and single cystic mass. In the early dynamic enhancement examination, the lesions were slightly circum-enhanced , and the center was enhanced in the later scan images. Inner hepatic vessels were compressed in 5 cases, vena cava and abdominal aortae were compressed in 3 cases. Pathological findings included fiber hyperplasia, hyaline degeneration, biliary duct hyperplasia, Iobule-like array. CONCLUSION： MR imaging is a better way to differentiate and diagnose MHL. MHL may be recognized by its characteristic occurrence in infancy and MR imaging features.展开更多
OBJECTIVE Mesenchymal hamartoma of the liver (MHL) is a rare disease that makes up about 5%-8% of primitive hepatic tumors in children. The etiology of MHL has been the subject of considerable discussion. The possibil...OBJECTIVE Mesenchymal hamartoma of the liver (MHL) is a rare disease that makes up about 5%-8% of primitive hepatic tumors in children. The etiology of MHL has been the subject of considerable discussion. The possibility of malignant transformation of MHL is inclusive. To enhance the recognition of MHL in children, we have review the procedures in diagnosis and treatment and present 4 of our own cases. METHODS The clinical characteristics of MHL in 4 children including history, physical examination, lab examination, imaging data and pathology were analyzed and discussed and related to reports from the literature. RESULTS All the cases were diagnosed with B-ultrasonography and CT preoperatively, and were confirmed intra-operatively and histologically. Satisfactory results were reached postoperatively. CONCLUSION MHL is an uncommon benign lesion in children. The main presentation is abdominal painless mass. Diagnosis is aided with B-ultrasonography and CT preoperatively. Complete tumor removal is the best choice for MHL treatment resulting in a good outcome.展开更多
文摘AIM： To describe the imaging features of hepatic mesenchymal hamartoma with emphasis on magnetic resonance imaging （MRI） compared to histopathologic results. METHODS： Spin-echo sequence（SE）,fast spin-echo sequence（FSE） were detected in 12 children （7 males,5 females） with mesenchymal hamartoma of the liver （IVlHL）, aged 1.2 months to 12 years,（ mean age, 6.3 years） by axial, saggital, coronary plain imaging with an Elscint 2.0T MR equipment. Their main symptoms were abdominal mass （5 cases）, enlarged liver （8 cases）, abdominal pain （1 case） and anemia （2 cases）, and negative alpha-fetoprotein. Dynamic enhancement examination was added in 2 cases. RESULTS： Six cases had single mass type of MHL, in which 3 cases had solid masses showing slight low- signal-intensity in TlWI, and irregular high-signal- intensity in T2WI, 1 case had a cystic-solid mixed mass showing several border-clear cysts in a solid mass, 2 cases had cystic masses with multi-septa. Five cases had diffuse and multifocal lesions type of MHL with its signal intensity being similar to that of the solid mass. One case had a combined diffuse and single cystic mass. In the early dynamic enhancement examination, the lesions were slightly circum-enhanced , and the center was enhanced in the later scan images. Inner hepatic vessels were compressed in 5 cases, vena cava and abdominal aortae were compressed in 3 cases. Pathological findings included fiber hyperplasia, hyaline degeneration, biliary duct hyperplasia, Iobule-like array. CONCLUSION： MR imaging is a better way to differentiate and diagnose MHL. MHL may be recognized by its characteristic occurrence in infancy and MR imaging features.
文摘OBJECTIVE Mesenchymal hamartoma of the liver (MHL) is a rare disease that makes up about 5%-8% of primitive hepatic tumors in children. The etiology of MHL has been the subject of considerable discussion. The possibility of malignant transformation of MHL is inclusive. To enhance the recognition of MHL in children, we have review the procedures in diagnosis and treatment and present 4 of our own cases. METHODS The clinical characteristics of MHL in 4 children including history, physical examination, lab examination, imaging data and pathology were analyzed and discussed and related to reports from the literature. RESULTS All the cases were diagnosed with B-ultrasonography and CT preoperatively, and were confirmed intra-operatively and histologically. Satisfactory results were reached postoperatively. CONCLUSION MHL is an uncommon benign lesion in children. The main presentation is abdominal painless mass. Diagnosis is aided with B-ultrasonography and CT preoperatively. Complete tumor removal is the best choice for MHL treatment resulting in a good outcome.
