Objective: To evaluate the ctinicat efficacy of music therapy in the treatment of children with cerebrat patsy by systematic review and meta-anatysis. Methods: A comprehensive search of China Knowledge Network, Wan fa...Objective: To evaluate the ctinicat efficacy of music therapy in the treatment of children with cerebrat patsy by systematic review and meta-anatysis. Methods: A comprehensive search of China Knowledge Network, Wan fang, VIP database and foreign databases PubMed and Cochrane Library was conducted from the setup of database to March 2019. After reading and screening them carefully, 14 qualified literates were got. Then extracted relevant data, and evaluated the quality and risk bias with Revman5.3.3 software. Results: There is no significant difference between music therapy in improving ctinostatism and the ability of rowing over (P > 0.05). However, music therapy has significant difference in improving sitting, running, and jumping movements, and it can atso relieve muscte spasm, improve muscte tension and stabilize children's emotions in the course of treatment and the P values of which were att tess than 0.05. Conclusion: The music therapy has a certain effect for the treatment of pediatric cerebrat patsy, especiatty in improving children's gross and fine motor abilities, which has a certain ctinicat guiding significance for rehabilitation of children with cerebrat patsy. Key words: Pediatric cerebrat patsy, Music therapy, Meta-anatysisy Ctinicat efficacyObjective: To evaluate the ctinicat efficacy of music therapy in the treatment of children with cerebrat patsy by systematic review and meta-anatysis. Methods: A comprehensive search of China Knowledge Network, Wan fang, VIP database and foreign databases PubMed and Cochrane Library was conducted from the setup of database to March 2019. After reading and screening them carefuLy, 14 qualified [iterates were got. Then extracted relevant data, and evaluated the quality and risk bias with Revman5.3.3 software. Results: There is no significant difference between music therapy in improving ctinostatism and the ability of rowing over (P > 0.05). However, music therapy has significant difference in improving sitting, running, and jumping movements, and it can atso relieve muscte spasm, improve muscte tension and stabilize children's emotions in the course of treatment and the P values of which were att tess than 0.05. Conclusion: The music therapy has a certain effect for the treatment of pediatric cerebrat patsy, especiatty in improving children's gross and fine motor abilities, which has a certain ctinicat guiding significance for rehabilitation of children with cerebrat patsy.展开更多
Background：One-lung ventilation （OLV） is a common ventilation technology during thoracic surgery that can cause serious clinical problems.We aimed to conduct a meta-analysis to compare oxygenation and intrapulmonar...Background：One-lung ventilation （OLV） is a common ventilation technology during thoracic surgery that can cause serious clinical problems.We aimed to conduct a meta-analysis to compare oxygenation and intrapulmonary shunt during OLV in adults undergoing thoracic surgery with dexmedetomidine （Dex） versus placebo to assess the influence and safety of using Dex.Methods：Randomized controlled trials comparing lung protection in patients who underwent thoracic surgery with Dex or a placebo were retrieved from PubMed,EMBASE,MEDLINE,Cochrane Library,and China CNKI database.The following information was extracted from the paper：arterial oxygen partial pressure （PaO2）,PaO2/inspired oxygen concentration （PaO2/FiO2,oxygenation index [OI]）,intrapulmonary shunt （calculated as Qs/Qt）,mean arterial pressure （MAP）,heart rate （HR）,tumor necrosis factor-α （TNF-α）,interleukin （IL）-6,superoxide dismutase （SOD）,and malondialdehyde （MDA）.Results：Fourteen randomized controlled trials were included containing a total of 625 patients.Compared with placebo group,Dex significantly increased PaO2/FiO2 （standard mean difference [SMD] =0.98,95% confidence interval [CI] [0.72,1.23],P 〈 0.00001）.Besides,Qs/Qt （SMD=-1.22,95% CI [-2.20,-0.23],P =0.020）,HR （SMD=-0.69,95% CI [-1.20,0.17],P =0.009）,MAP （SMD=-0.44,95% CI [-0.84,0.04],P =0.030）,the concentrations ofTNF-α （SMD =-1.55,95% CI [-2.16,-0.95],P 〈0.001）,and IL-6 （SMD =-1.53,95% CI [-2.37,-0.70],P =0.0003） were decreased in the treated group,when compared to placebo group.No significant difference was found in MDA （SMD =-1.14,95% CI [-3.48,1.20],P =0.340） and SOD （SMD =0.41,95% CI [-0.29,1.10],P =0.250） between the Dex group and the placebo group.Funnel plots did not detect any significant publication bias.Conclusions：Dex may improve OI and reduce intrapulmonary shunt during OLV in adults undergoing thoracic surgery.However,this conclusion might be weakened by the limited number of pooled studies and patients.展开更多
文摘Objective: To evaluate the ctinicat efficacy of music therapy in the treatment of children with cerebrat patsy by systematic review and meta-anatysis. Methods: A comprehensive search of China Knowledge Network, Wan fang, VIP database and foreign databases PubMed and Cochrane Library was conducted from the setup of database to March 2019. After reading and screening them carefully, 14 qualified literates were got. Then extracted relevant data, and evaluated the quality and risk bias with Revman5.3.3 software. Results: There is no significant difference between music therapy in improving ctinostatism and the ability of rowing over (P > 0.05). However, music therapy has significant difference in improving sitting, running, and jumping movements, and it can atso relieve muscte spasm, improve muscte tension and stabilize children's emotions in the course of treatment and the P values of which were att tess than 0.05. Conclusion: The music therapy has a certain effect for the treatment of pediatric cerebrat patsy, especiatty in improving children's gross and fine motor abilities, which has a certain ctinicat guiding significance for rehabilitation of children with cerebrat patsy. Key words: Pediatric cerebrat patsy, Music therapy, Meta-anatysisy Ctinicat efficacyObjective: To evaluate the ctinicat efficacy of music therapy in the treatment of children with cerebrat patsy by systematic review and meta-anatysis. Methods: A comprehensive search of China Knowledge Network, Wan fang, VIP database and foreign databases PubMed and Cochrane Library was conducted from the setup of database to March 2019. After reading and screening them carefuLy, 14 qualified [iterates were got. Then extracted relevant data, and evaluated the quality and risk bias with Revman5.3.3 software. Results: There is no significant difference between music therapy in improving ctinostatism and the ability of rowing over (P > 0.05). However, music therapy has significant difference in improving sitting, running, and jumping movements, and it can atso relieve muscte spasm, improve muscte tension and stabilize children's emotions in the course of treatment and the P values of which were att tess than 0.05. Conclusion: The music therapy has a certain effect for the treatment of pediatric cerebrat patsy, especiatty in improving children's gross and fine motor abilities, which has a certain ctinicat guiding significance for rehabilitation of children with cerebrat patsy.
文摘Background：One-lung ventilation （OLV） is a common ventilation technology during thoracic surgery that can cause serious clinical problems.We aimed to conduct a meta-analysis to compare oxygenation and intrapulmonary shunt during OLV in adults undergoing thoracic surgery with dexmedetomidine （Dex） versus placebo to assess the influence and safety of using Dex.Methods：Randomized controlled trials comparing lung protection in patients who underwent thoracic surgery with Dex or a placebo were retrieved from PubMed,EMBASE,MEDLINE,Cochrane Library,and China CNKI database.The following information was extracted from the paper：arterial oxygen partial pressure （PaO2）,PaO2/inspired oxygen concentration （PaO2/FiO2,oxygenation index [OI]）,intrapulmonary shunt （calculated as Qs/Qt）,mean arterial pressure （MAP）,heart rate （HR）,tumor necrosis factor-α （TNF-α）,interleukin （IL）-6,superoxide dismutase （SOD）,and malondialdehyde （MDA）.Results：Fourteen randomized controlled trials were included containing a total of 625 patients.Compared with placebo group,Dex significantly increased PaO2/FiO2 （standard mean difference [SMD] =0.98,95% confidence interval [CI] [0.72,1.23],P 〈 0.00001）.Besides,Qs/Qt （SMD=-1.22,95% CI [-2.20,-0.23],P =0.020）,HR （SMD=-0.69,95% CI [-1.20,0.17],P =0.009）,MAP （SMD=-0.44,95% CI [-0.84,0.04],P =0.030）,the concentrations ofTNF-α （SMD =-1.55,95% CI [-2.16,-0.95],P 〈0.001）,and IL-6 （SMD =-1.53,95% CI [-2.37,-0.70],P =0.0003） were decreased in the treated group,when compared to placebo group.No significant difference was found in MDA （SMD =-1.14,95% CI [-3.48,1.20],P =0.340） and SOD （SMD =0.41,95% CI [-0.29,1.10],P =0.250） between the Dex group and the placebo group.Funnel plots did not detect any significant publication bias.Conclusions：Dex may improve OI and reduce intrapulmonary shunt during OLV in adults undergoing thoracic surgery.However,this conclusion might be weakened by the limited number of pooled studies and patients.
