Intraorbital Mature Teratoma in Infant

Intraorbital mature teratoma is a rare congenital tumor of slow evolution that can compromise vision. Objectives: We describe the clinical and therapeutic aspects of a mature teratoma in childhood with a literature review. Clinical Case: It was a 12-year-old who had a progressive straight monocular exophthalmia with blindness. CT without and with contrast injection showed a double component intracolonic invasive tumor with partial contrast acquisition after injection. This tumor respected the bone walls of the orbit. The treatment was surgical by conjunctival dissection of the tumor and enucleation. This allowed the tumor to be fully excised under an operating microscope. The operating procedures were simple. Anatomopathology confirmed the nature of the tumor by visualizing the presence of a squamous epithelium by the high-magnification (X20) method of hematoxylin and eosin. Conclusion: Mature intraorbital teratoma is an embryonic tumor with early diagnosis the finding in an older child remains rare. Complete surgical excision allows healing.

Preliminary results of Preserflo Microshunt versus Preserflo Microshunt and Ologen implantation

Purpose:To report preliminary 6-month results on the use of the Preserflo Microshunt implant with and without Ologen in 50 pseudophakic eyes with moderate to advanced primary open-angle glaucoma(POAG).Methods:Fifty pseudophakic eyes underwent ab externo Preserflo Microshunt implantation.Data was gathered retrospectively and two groups were then created,group A with application of MMC 0.2 mg/ml and group B with MMC 0.2 mg/ml and Ologen collagen matrix(OCM)implantation.Absolute success was regarded as the percentage of eyes achieving:a)5≤intraocular pressure(IOP)≤13 mmHg,b)5≤IOP≤16 mmHg,and c)5≤IOP≤21 mmHg without additional medication or surgery and qualified success was regarded as the percentage of eyes achieving a)IOP≤13 mmHg,b)IOP≤16 mmHg,and c)IOP≤21 mmHg with or without medication.Evaluation was performed using a log-rank Kaplan-Meier test.A scatterplot analysis presented the treatment effect data of all eyes with a minimum of 20%IOP reduction per case.Failure was defined as requiring additional surgery,IOP greater than 21 mmHg with or without medication and failure to reach 20%IOP reduction.Results:Mean postoperative IOP was significantly lower in both groups.IOP decreased by 49.06%in group A and by 53.01%in group B at 6 months(P<0.88),respectively.Medication use was lower in both groups(Wilcoxon test,P<0.001).The absolute and qualified success rates were not statistically significant between the groups(all P>0.05).Cumulative IOP results per case were not statistically different in group A compared with group B.One revision surgery in group A(4%failure rate)and three in group B(12%failure rate)were performed.Conclusions:Both groups showed equal results in terms of cumulative and mean IOP reduction,medication reduction as well as in absolute and qualified success rates.No significant difference was found in any parameters tested between Preserflo Microshunt with MMC 0.2 mg/ml and with or without OCM implantation at 6 months.Long-term follow-up is required to further evaluate this data.