The Association between Interpersonal Relationship and Erectile Dysfunction of Middle-Aged and Elderly Men in a Rural Area of Zhejiang,China

Objective:To explore the association between interpersonal relationship and erectile dysfunction(ED)of middle-aged and elderly men.Methods:A population-based cross-sectional research was conducted in the rural area of Jiashan County,Zhejiang Province,in 2016.Middle-aged and elderly men(aged 40-80)were selected as study participants.The face-to-face questionnaire was collected,including basic information,lifestyles,interpersonal relationship,and sexual function.The interpersonal relationship was evaluated based on marital relationship,neighborhood relationship,and relatives/friends relationship.According to the International index of erectile function,the study participants were divided into ED group(mild ED,moderate-to-severe ED),and non-ED group.Correlations were evaluated between interpersonal relationship indices and the prevalence or the severity of ED.Potential confounders were adjusted by the logistical regression model.Results:There were 674 study participants with average age of 60.4±8.5 years,and 489 ED patients with prevalence of 72.6%.With age increasing,the prevalence and the severity of ED increased significantly.The men who could get help from spouse when an emergency occurred or who were more cared about by their neighbors had lower ED risk,and odds ratios(ORs)(95%confidence intervals[CIs])were 0.23(0.13-0.42)and 0.58(0.46-0.75),respectively.After the adjustment of the covariates(age,education degree,household income,smoking,and drinking),the ORs(95%CIs)were 0.29(0.14-0.60)and 0.54(0.39-0.74),respectively.Good marital relationship and good neighborhood relationship were associated with a less severity of ED.

中老年男性饮酒与2型糖尿病发病关系的前瞻性队列研究

目的 探讨饮酒与中老年男性2型糖尿病（T2DM）发病风险的关联性。方法 研究人群来源于东风同济队列，该队列于2008年在湖北省招募了27 009名东风汽车公司离、退休职工，基线调查采用半结构化问卷收集饮酒信息和相关协变量，并进行了体格检查、血糖和血脂等测定。从队列中选取男性并排除基线调查时已患糖尿病、冠心病、卒中和恶性肿瘤者，最终纳入6 784名男性。2013年进行随访，通过研究对象的医疗保险号收集其疾病或死亡结局。应用COX比例风险模型分析不同饮酒特征和模式与T2DM的关联性。结果 6 784名研究对象中，3 541名从不饮酒者共随访15 852.2人年，新发T2DM 270例，发病密度为1 703.2/10万人年；3 243名饮酒者共随访14 509.8人年，新发T2DM 258例，发病密度为1 778.1/10万人年。多因素COX比例风险模型显示：与不饮酒人群相比，饮酒人群T2DM发生风险总体上未升高[HR（95%CI）：1.09（0.91~1.30）]，但平均乙醇摄入量〉20 g/d和饮酒频率高于7次/周的饮酒者T2DM发生风险均升高[HR（95%CI）值分别为1.27（1.02~1.58）和1.35 （1.00~1.83）]；饮酒频率〉7次/周的人群中，单次乙醇摄入量为0.01~40和〉40 g者发生T2DM的HR（95%CI）值分别为1.48（1.05~2.09）和1.27（0.80~2.01）。结论 总体上饮酒与T2DM发生风险无关，但平均乙醇摄入量〉20 g/d或饮酒频率〉7次/周会增加T2DM发生风险。