BACKGROUND Hypertensive intracerebral hemorrhage is a common critical disease of the nervous system,comprising one fifth of all acute cerebrovascular diseases and has a high disability and mortality rate.It severely a...BACKGROUND Hypertensive intracerebral hemorrhage is a common critical disease of the nervous system,comprising one fifth of all acute cerebrovascular diseases and has a high disability and mortality rate.It severely affects the patients’quality of life.AIM To analyze the short-term effect and long-term prognosis of neuroendoscopic minimally invasive surgery for hypertensive intracerebral hemorrhage.METHODS From March 2018 to May 2020,118 patients with hypertensive intracerebral hemorrhage were enrolled in our study and divided into a control group and observation group according to the surgical plan.The control group used a hard-channel minimally invasive puncture and drainage procedure.The observation group underwent minimally invasive neuroendoscopic surgery.The changes in the levels of serum P substances(SP),inflammatory factors[tumor necrosis factor-α,interleukin-6(IL-6),IL-10],and the National Hospital Stroke Scale(NIHSS)and Barthel index scores were recorded.Surgery related indicators and prognosis were compared between the two groups.RESULTS The operation time(105.26±28.35)of the observation group was min longer than that of the control group,and the volume of intraoperative bleeding was 45.36±10.17 mL more than that of the control group.The hematoma clearance rates were 88.58%±4.69%and 94.47%±4.02%higher than those of the control group at 48 h and 72 h,respectively.Good prognosis rate(86.44%)was higher in the observation group than in the control group,and complication rate(5.08%)was not significantly different from that of the control group(P>0.05).The SP level and Barthel index score of the two groups increased(P<0.05)and the inflam-matory factors and NIHSS score decreased(P<0.05).The cytokine levels,NIHSS score,and Barthel index score were better in the observation group than in the control group(P<0.05).CONCLUSION Neuroendoscopic minimally invasive surgery is more complicated than hard channel minimally invasive puncture drainage in the treatment of hypertensive intracerebral hemorrhage;however,hematoma clearance is more thorough,and the short-term effect and long-term prognosis are better than hard channel minimally invasive puncture drainage.展开更多
目的:探讨微创血肿穿刺引流术与显微镜下血肿清除术治疗高血压性基底节区脑出血的疗效及对脑血管痉挛的影响。方法:选取2020年9月-2023年9月期间本院收治的76例高血压性基底节区脑出血患者作为研究对象。随机将患者分为对照组和研究组,...目的:探讨微创血肿穿刺引流术与显微镜下血肿清除术治疗高血压性基底节区脑出血的疗效及对脑血管痉挛的影响。方法:选取2020年9月-2023年9月期间本院收治的76例高血压性基底节区脑出血患者作为研究对象。随机将患者分为对照组和研究组,每组各38例。对照组予以微创血肿穿刺引流术,研究组予显微镜下血肿清除术。分析比较两组的血肿清除效果、脑血管痉挛的发生率及术后神经功能与日常生活自理能力恢复情况。结果:治疗后,研究组血肿清除率显著高于对照组(P<0.05)。研究组的脑血管痉挛发生率显著低于对照组(P<0.05)。治疗前,两组美国国力卫生院卒中量表(National institutes of health stroke scale,NIHSS)评分和日常生活活动能力(Modified Barthel Index,MBI评分)均无显著差异(P>0.05);治疗后,研究组的NIHSS评分显著低于对照组,MBI评分显著高于对照组(P<0.05)。结论:对高血压性基底节区脑出血患者采用显微镜下血肿清除术进行治疗,能提升血肿清除效果、降低脑血管痉挛的发生率,促进患者术后神经功能的恢复,提高其日常生活自理能力。展开更多
文摘BACKGROUND Hypertensive intracerebral hemorrhage is a common critical disease of the nervous system,comprising one fifth of all acute cerebrovascular diseases and has a high disability and mortality rate.It severely affects the patients’quality of life.AIM To analyze the short-term effect and long-term prognosis of neuroendoscopic minimally invasive surgery for hypertensive intracerebral hemorrhage.METHODS From March 2018 to May 2020,118 patients with hypertensive intracerebral hemorrhage were enrolled in our study and divided into a control group and observation group according to the surgical plan.The control group used a hard-channel minimally invasive puncture and drainage procedure.The observation group underwent minimally invasive neuroendoscopic surgery.The changes in the levels of serum P substances(SP),inflammatory factors[tumor necrosis factor-α,interleukin-6(IL-6),IL-10],and the National Hospital Stroke Scale(NIHSS)and Barthel index scores were recorded.Surgery related indicators and prognosis were compared between the two groups.RESULTS The operation time(105.26±28.35)of the observation group was min longer than that of the control group,and the volume of intraoperative bleeding was 45.36±10.17 mL more than that of the control group.The hematoma clearance rates were 88.58%±4.69%and 94.47%±4.02%higher than those of the control group at 48 h and 72 h,respectively.Good prognosis rate(86.44%)was higher in the observation group than in the control group,and complication rate(5.08%)was not significantly different from that of the control group(P>0.05).The SP level and Barthel index score of the two groups increased(P<0.05)and the inflam-matory factors and NIHSS score decreased(P<0.05).The cytokine levels,NIHSS score,and Barthel index score were better in the observation group than in the control group(P<0.05).CONCLUSION Neuroendoscopic minimally invasive surgery is more complicated than hard channel minimally invasive puncture drainage in the treatment of hypertensive intracerebral hemorrhage;however,hematoma clearance is more thorough,and the short-term effect and long-term prognosis are better than hard channel minimally invasive puncture drainage.
文摘目的:探讨微创血肿穿刺引流术与显微镜下血肿清除术治疗高血压性基底节区脑出血的疗效及对脑血管痉挛的影响。方法:选取2020年9月-2023年9月期间本院收治的76例高血压性基底节区脑出血患者作为研究对象。随机将患者分为对照组和研究组,每组各38例。对照组予以微创血肿穿刺引流术,研究组予显微镜下血肿清除术。分析比较两组的血肿清除效果、脑血管痉挛的发生率及术后神经功能与日常生活自理能力恢复情况。结果:治疗后,研究组血肿清除率显著高于对照组(P<0.05)。研究组的脑血管痉挛发生率显著低于对照组(P<0.05)。治疗前,两组美国国力卫生院卒中量表(National institutes of health stroke scale,NIHSS)评分和日常生活活动能力(Modified Barthel Index,MBI评分)均无显著差异(P>0.05);治疗后,研究组的NIHSS评分显著低于对照组,MBI评分显著高于对照组(P<0.05)。结论:对高血压性基底节区脑出血患者采用显微镜下血肿清除术进行治疗,能提升血肿清除效果、降低脑血管痉挛的发生率,促进患者术后神经功能的恢复,提高其日常生活自理能力。
