Objective: To investigate the changes of inflammatory response, stress response and urodynamic changes after total pelvic floor reconstruction in patients with pelvic organ prolapse. Methods: According to random data ...Objective: To investigate the changes of inflammatory response, stress response and urodynamic changes after total pelvic floor reconstruction in patients with pelvic organ prolapse. Methods: According to random data table method, 80 cases of pelvic organ prolapse were randomly divided into the control group (n=40) and observation group (n=40), patients in the control group were given conventional vaginal hysterectomy plus vaginal wall repair sugery and the observation group received total pelvic floor reconstruction. The levels of the serum inflammatory factor,oxidative stress before and after surgery, and postoperative urodynamic changes were compared. Results: The levels of serum hs-CRP, IL-1β,TNF-α, NE, E and Ins in the two groups before treatment were not statistically significant. Compared with the group before treatment, the levels of hs-CRP, IL-1β, TNF-α, NE, E were significantly increased in both groups after treatment, and the observation group levels were significantly lower than those in the control group after treatment;in terms of urodynamics, the postoperative maximal bladder volume and Qmax were significantly higher in the observation group than in the control group, the postoperative levels of PdetQMax, PdetMax and PVR in the observation group were significantly lower than those in the control group. Conclusion: Compared with vaginal hysterectomy plus vaginal wall repair sugery, total pelvic floor reconstruction can light the patient's inflammation, stress response and improve the patient's urinary function, and the overall effect is better which has important clinical value.展开更多
Background Mesh reconstruction has been proved to be an effective method in incisional hernia repairment. This study was designed to evaluate the effect of reconstructing the pelvic floor with the high-inlay expanded ...Background Mesh reconstruction has been proved to be an effective method in incisional hernia repairment. This study was designed to evaluate the effect of reconstructing the pelvic floor with the high-inlay expanded polytetrafluoroethylene （ePTFE） GORE-TEX Dual Mesh （WLGore And Associates, Flagstuff, USA） in abdominoperineal resection. Methods Sixty patients who underwent abdominopedneal resection for rectal cancer were assigned to 2 groups. The pelvic peritoneum was closed by routine sutures in group 1 and reconstructed with ePTFE in group 2. Postoperative complications and related items were evaluated and the patients were followed up. Results Time of confining to bed, bowel function recovery, fasting, and detaining drainage were significantly different between two groups （P 〈0.05）. In group 1, three patients developed bowel obstruction （10%）, while no bowel obstruction was observed in group 2. Conclusion Reconstruction of the pelvic floor using ePTFE results in quicker postoperative recovery and could decrease the risk of postoperative intestinal obstruction.展开更多
With increasing age,pelvic organ prolapse(POP),due to its high incidence,has become a common disease that seriously affects patients’quality of life and places a heavy economic burden on families and society.Transvag...With increasing age,pelvic organ prolapse(POP),due to its high incidence,has become a common disease that seriously affects patients’quality of life and places a heavy economic burden on families and society.Transvaginal mesh(TVM)is a minimally invasive and effective treatment for POP,although its use remains controversial due to the potential risk of mesh-related complications.The US Foods and Drugs Administration,along with authorities in England,Australia,New Zealand,and other countries,have banned the sale and distribution of commercial TVM kits designed for POP.The TVM procedure remains an option for POP treatment and still appeals to many surgeons and patients today in Asia and most European countries,which suggests that a considerable number of POP patients can benefit from its continued refinement.Here we introduce the Huaxi protocol of the TVM plant for the treatment of POP.展开更多
目的:探讨改良LeFort阴道封闭术与改良全盆底重建术对老年女性重度盆腔器官脱垂(pelvic organ prolapse,POP)的影响。方法:选取2016年2月17日—2021年2月17日贵州医科大学附属医院妇科收治的82例老年重度POP女性。根据随机抽签方式将其...目的:探讨改良LeFort阴道封闭术与改良全盆底重建术对老年女性重度盆腔器官脱垂(pelvic organ prolapse,POP)的影响。方法:选取2016年2月17日—2021年2月17日贵州医科大学附属医院妇科收治的82例老年重度POP女性。根据随机抽签方式将其分成对照组和试验组,各41例。对照组给予改良Le Fort阴道封闭术,试验组给予改良全盆底重建术。比较两组围手术期指标,相关指标,术前、术后半年临床症状及生活质量,术前、术后1周排尿、排便情况。结果:两组手术时间、住院时间、留置尿管时间、术中出血量比较,差异无统计学意义(P>0.05)。试验组治愈率高于对照组,复发率、新发压力性尿失禁发生率、再次手术发生率均低于对照组,差异有统计学意义(P<0.05)。术后半年,两组盆底功能障碍问卷(pelvic floor distress inventory-short form 20,PFDI-20)评分、盆底功能影响问卷简表(pelvic floor impact questionnaire--short form 7,PFIQ-7)评分降低,试验组PFDI-20评分、PFIQ-7评分均低于对照组,差异有统计学意义(P<0.05)。术后1周,试验组尿急、尿频、排尿困难、排便困难发生率均低于对照组,差异有统计学意义(P<0.05)。结论:改良全盆底重建术更有助于改善患者脱垂复发率,改善患者排尿、排便情况,手术十分安全有效。展开更多
文摘Objective: To investigate the changes of inflammatory response, stress response and urodynamic changes after total pelvic floor reconstruction in patients with pelvic organ prolapse. Methods: According to random data table method, 80 cases of pelvic organ prolapse were randomly divided into the control group (n=40) and observation group (n=40), patients in the control group were given conventional vaginal hysterectomy plus vaginal wall repair sugery and the observation group received total pelvic floor reconstruction. The levels of the serum inflammatory factor,oxidative stress before and after surgery, and postoperative urodynamic changes were compared. Results: The levels of serum hs-CRP, IL-1β,TNF-α, NE, E and Ins in the two groups before treatment were not statistically significant. Compared with the group before treatment, the levels of hs-CRP, IL-1β, TNF-α, NE, E were significantly increased in both groups after treatment, and the observation group levels were significantly lower than those in the control group after treatment;in terms of urodynamics, the postoperative maximal bladder volume and Qmax were significantly higher in the observation group than in the control group, the postoperative levels of PdetQMax, PdetMax and PVR in the observation group were significantly lower than those in the control group. Conclusion: Compared with vaginal hysterectomy plus vaginal wall repair sugery, total pelvic floor reconstruction can light the patient's inflammation, stress response and improve the patient's urinary function, and the overall effect is better which has important clinical value.
文摘Background Mesh reconstruction has been proved to be an effective method in incisional hernia repairment. This study was designed to evaluate the effect of reconstructing the pelvic floor with the high-inlay expanded polytetrafluoroethylene （ePTFE） GORE-TEX Dual Mesh （WLGore And Associates, Flagstuff, USA） in abdominoperineal resection. Methods Sixty patients who underwent abdominopedneal resection for rectal cancer were assigned to 2 groups. The pelvic peritoneum was closed by routine sutures in group 1 and reconstructed with ePTFE in group 2. Postoperative complications and related items were evaluated and the patients were followed up. Results Time of confining to bed, bowel function recovery, fasting, and detaining drainage were significantly different between two groups （P 〈0.05）. In group 1, three patients developed bowel obstruction （10%）, while no bowel obstruction was observed in group 2. Conclusion Reconstruction of the pelvic floor using ePTFE results in quicker postoperative recovery and could decrease the risk of postoperative intestinal obstruction.
基金National Key Research and Development Program of China,Grant/Award Numbers:2021YFC2009100,2021YFC2009102Natural Science Foundation of Sichuan Province,Grant/Award Number:2022NSFSC1308。
文摘With increasing age,pelvic organ prolapse(POP),due to its high incidence,has become a common disease that seriously affects patients’quality of life and places a heavy economic burden on families and society.Transvaginal mesh(TVM)is a minimally invasive and effective treatment for POP,although its use remains controversial due to the potential risk of mesh-related complications.The US Foods and Drugs Administration,along with authorities in England,Australia,New Zealand,and other countries,have banned the sale and distribution of commercial TVM kits designed for POP.The TVM procedure remains an option for POP treatment and still appeals to many surgeons and patients today in Asia and most European countries,which suggests that a considerable number of POP patients can benefit from its continued refinement.Here we introduce the Huaxi protocol of the TVM plant for the treatment of POP.
文摘目的:探讨改良LeFort阴道封闭术与改良全盆底重建术对老年女性重度盆腔器官脱垂(pelvic organ prolapse,POP)的影响。方法:选取2016年2月17日—2021年2月17日贵州医科大学附属医院妇科收治的82例老年重度POP女性。根据随机抽签方式将其分成对照组和试验组,各41例。对照组给予改良Le Fort阴道封闭术,试验组给予改良全盆底重建术。比较两组围手术期指标,相关指标,术前、术后半年临床症状及生活质量,术前、术后1周排尿、排便情况。结果:两组手术时间、住院时间、留置尿管时间、术中出血量比较,差异无统计学意义(P>0.05)。试验组治愈率高于对照组,复发率、新发压力性尿失禁发生率、再次手术发生率均低于对照组,差异有统计学意义(P<0.05)。术后半年,两组盆底功能障碍问卷(pelvic floor distress inventory-short form 20,PFDI-20)评分、盆底功能影响问卷简表(pelvic floor impact questionnaire--short form 7,PFIQ-7)评分降低,试验组PFDI-20评分、PFIQ-7评分均低于对照组,差异有统计学意义(P<0.05)。术后1周,试验组尿急、尿频、排尿困难、排便困难发生率均低于对照组,差异有统计学意义(P<0.05)。结论:改良全盆底重建术更有助于改善患者脱垂复发率,改善患者排尿、排便情况,手术十分安全有效。
