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A 256 Gb/s electronic−photonic monolithically integrated transceiver in 45 nm CMOS 被引量:1
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作者 Ang Li Qianli Ma +15 位作者 Yujun Xie Yongliang Xiong Yingjie Ma Han Liu Ye Jin Menghan Yang Guike Li Haoran Yin Minye Zhu Yang Qu Peng Wang Daofa Wang Wei Li Liyuan Liu Nan Qi Ming Li 《Journal of Semiconductors》 EI CAS CSCD 2024年第7期7-10,共4页
With the explosive development of artificial intelligence(AI),machine learning(ML),and high-performance comput-ing(HPC),the ever-growing data movement is asking for high density interconnects with higher bandwidth(BW)... With the explosive development of artificial intelligence(AI),machine learning(ML),and high-performance comput-ing(HPC),the ever-growing data movement is asking for high density interconnects with higher bandwidth(BW),lower power and lower latency[1−3].The optical I/O leverages silicon photonic(SiPh)technology to enable high-density large-scale integrated photonics. 展开更多
关键词 Gb/s TRANSCEIVER monolithic
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Proposal for sequential Stern-Gerlach experiment with programmable quantum processors
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作者 胡孟军 缪海兴 张永生 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第2期131-136,共6页
The historical significance of the Stern–Gerlach(SG)experiment lies in its provision of the initial evidence for space quantization.Over time,its sequential form has evolved into an elegant paradigm that effectively ... The historical significance of the Stern–Gerlach(SG)experiment lies in its provision of the initial evidence for space quantization.Over time,its sequential form has evolved into an elegant paradigm that effectively illustrates the fundamental principles of quantum theory.To date,the practical implementation of the sequential SG experiment has not been fully achieved.In this study,we demonstrate the capability of programmable quantum processors to simulate the sequential SG experiment.The specific parametric shallow quantum circuits,which are suitable for the limitations of current noisy quantum hardware,are given to replicate the functionality of SG devices with the ability to perform measurements in different directions.Surprisingly,it has been demonstrated that Wigner’s SG interferometer can be readily implemented in our sequential quantum circuit.With the utilization of the identical circuits,it is also feasible to implement Wheeler’s delayed-choice experiment.We propose the utilization of cross-shaped programmable quantum processors to showcase sequential experiments,and the simulation results demonstrate a strong alignment with theoretical predictions.With the rapid advancement of cloud-based quantum computing,such as BAQIS Quafu,it is our belief that the proposed solution is well-suited for deployment on the cloud,allowing for public accessibility.Our findings not only expand the potential applications of quantum computers,but also contribute to a deeper comprehension of the fundamental principles underlying quantum theory. 展开更多
关键词 sequential Stern-Gerlach quantum circuit quantum processor
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Hybrid Strategy of Partitioned and Monolithic Methods for Solving Strongly Coupled Analysis of Inverse and Direct Piezoelectric and Circuit Coupling
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作者 Daisuke Ishihara Syunnosuke Nozaki +1 位作者 Tomoya Niho Naoto Takayama 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第8期1371-1386,共16页
The inverse and direct piezoelectric and circuit coupling are widely observed in advanced electro-mechanical systems such as piezoelectric energy harvesters.Existing strongly coupled analysis methods based on direct n... The inverse and direct piezoelectric and circuit coupling are widely observed in advanced electro-mechanical systems such as piezoelectric energy harvesters.Existing strongly coupled analysis methods based on direct numerical modeling for this phenomenon can be classified into partitioned or monolithic formulations.Each formulation has its advantages and disadvantages,and the choice depends on the characteristics of each coupled problem.This study proposes a new option:a coupled analysis strategy that combines the best features of the existing formulations,namely,the hybrid partitioned-monolithic method.The analysis of inverse piezoelectricity and the monolithic analysis of direct piezoelectric and circuit interaction are strongly coupled using a partitioned iterative hierarchical algorithm.In a typical benchmark problem of a piezoelectric energy harvester,this research compares the results from the proposed method to those from the conventional strongly coupled partitioned iterative method,discussing the accuracy,stability,and computational cost.The proposed hybrid concept is effective for coupled multi-physics problems,including various coupling conditions. 展开更多
关键词 Structure-piezoelectric-circuit interaction energy harvesting partitioned method monolithic method hybrid method
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Electrochemically Deposited CZTSSe Thin Films for Monolithic Perovskite Tandem Solar Cells with Efficiencies Over 17%
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作者 Sun Kyung Hwang Ik Jae Park +3 位作者 Se Won Seo Jae Hyun Park So Jeong Park Jin Young Kim 《Energy & Environmental Materials》 SCIE EI CAS CSCD 2024年第1期147-152,共6页
In spite of the high potential economic feasibility of the tandem solar cells consisting of the halide perovskite and the kesterite Cu2ZnSn(S,Se)4(CZTSSe),they have rarely been demonstrated due to the difficulty in im... In spite of the high potential economic feasibility of the tandem solar cells consisting of the halide perovskite and the kesterite Cu2ZnSn(S,Se)4(CZTSSe),they have rarely been demonstrated due to the difficulty in implementing solution-processed perovskite top cell on the rough surface of the bottom cells.Here,we firstly demonstrate an efficient monolithic two-terminal perovskite/CZTSSe tandem solar cell by significantly reducing the surface roughness of the electrochemically deposited CZTSSe bottom cell.The surface roughness(R_(rms))of the CZTSSe thin film could be reduced from 424 to 86 nm by using the potentiostatic mode rather than using the conventional galvanostatic mode,which can be further reduced to 22 nm after the subsequent ion-milling process.The perovskite top cell with a bandgap of 1.65 eV could be prepared using a solution process on the flattened CZTSSe bottom cell,resulting in the efficient perovskite/CZTSSe tandem solar cells.After the current matching between two subcells involving the thickness control of the perovskite layer,the best performing tandem device exhibited a high conversion efficiency of 17.5%without the hysteresis effect. 展开更多
关键词 CZTSSe monolithic tandem solar cells PEROVSKITE solution process surface roughness control
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Surface-functionalized hole-selective monolayer for high efficiency single-junction wide-bandgap and monolithic tandem perovskite solar cells
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作者 Devthade Vidyasagar Yeonghun Yun +13 位作者 Jae Yu Cho Hyemin Lee Kyung Won Kim Yong Tae Kim Sung Woong Yang Jina Jung Won Chang Choi Seonu Kim Rajendra Kumar Gunasekaran Seok Beom Kang Kwang Heo Dong Hoe Kim Jaeyeong Heo Sangwook Lee 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第1期317-326,I0008,共11页
Carbazole moiety-based 2PACz([2-(9H-carbazol-9-yl)ethyl]phosphonic acid)self-assembled monolayers(SAMs)are excellent hole-selective contact(HSC)materials with abilities to excel the charge-transferdynamics of perovski... Carbazole moiety-based 2PACz([2-(9H-carbazol-9-yl)ethyl]phosphonic acid)self-assembled monolayers(SAMs)are excellent hole-selective contact(HSC)materials with abilities to excel the charge-transferdynamics of perovskite solar cells(PSCs).Herein,we report a facile but powerful method to functionalize the surface of 2PACz-SAM,by which reproducible,highly stable,high-efficiency wide-bandgap PSCs can be obtained.The 2PACz surface treatment with various donor number solvents improves assembly of 2PACz-SAM and leave residual surface-bound solvent molecules on 2PACz-SAM,which increases perovskite grain size,retards halide segregation,and accelerates hole extraction.The surface functionalization achieves a high power conversion efficiency(PCE)of 17.62%for a single-junction wide-bandgap(~1.77 e V)PSC.We also demonstrate a monolithic all-perovskite tandem solar cell using surfaceengineered HSC,showing high PCE of 24.66%with large open-circuit voltage of 2.008 V and high fillfactor of 81.45%.Our results suggest this simple approach can further improve the tandem device,when coupled with a high-performance narrow-bandgap sub-cell. 展开更多
关键词 Perovskite solar cells 2PACz monolithic tandem solar cells Wide bandgap
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Efficient cache replacement framework based on access hotness for spacecraft processors
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作者 GAO Xin NIAN Jiawei +1 位作者 LIU Hongjin YANG Mengfei 《中国空间科学技术(中英文)》 CSCD 北大核心 2024年第2期74-88,共15页
A notable portion of cachelines in real-world workloads exhibits inner non-uniform access behaviors.However,modern cache management rarely considers this fine-grained feature,which impacts the effective cache capacity... A notable portion of cachelines in real-world workloads exhibits inner non-uniform access behaviors.However,modern cache management rarely considers this fine-grained feature,which impacts the effective cache capacity of contemporary high-performance spacecraft processors.To harness these non-uniform access behaviors,an efficient cache replacement framework featuring an auxiliary cache specifically designed to retain evicted hot data was proposed.This framework reconstructs the cache replacement policy,facilitating data migration between the main cache and the auxiliary cache.Unlike traditional cacheline-granularity policies,the approach excels at identifying and evicting infrequently used data,thereby optimizing cache utilization.The evaluation shows impressive performance improvement,especially on workloads with irregular access patterns.Benefiting from fine granularity,the proposal achieves superior storage efficiency compared with commonly used cache management schemes,providing a potential optimization opportunity for modern resource-constrained processors,such as spacecraft processors.Furthermore,the framework complements existing modern cache replacement policies and can be seamlessly integrated with minimal modifications,enhancing their overall efficacy. 展开更多
关键词 spacecraft processors cache management replacement policy storage efficiency memory hierarchy MICROARCHITECTURE
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A monolithic integrated medium wave Mercury Cadmium Telluride polarimetric focal plane array
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作者 CHEN Ze-Ji HUANG You-Wen +4 位作者 PU En-Xiang XIAO Hui-Shan XU Shi-Chun QIN Qiang KONG Jin-Cheng 《红外与毫米波学报》 SCIE EI CAS CSCD 北大核心 2024年第4期479-489,共11页
A medium wave(MW)640×512(25μm)Mercury Cadmium Telluride(HgCdTe)polarimetric focal plane array(FPA)was demonstrated.The micro-polarizer array(MPA)has been carefully designed in terms of line grating structure opt... A medium wave(MW)640×512(25μm)Mercury Cadmium Telluride(HgCdTe)polarimetric focal plane array(FPA)was demonstrated.The micro-polarizer array(MPA)has been carefully designed in terms of line grating structure optimization and crosstalk suppression.A monolithic fabrication process with low damage was explored,which was verified to be compatible well with HgCdTe devices.After monolithic integration of MPA,NETD<9.5 mK was still maintained.Furthermore,to figure out the underlying mechanism that dominat⁃ed the extinction ratio(ER),specialized MPA layouts were designed,and the crosstalk was experimentally vali⁃dated as the major source that impacted ER.By expanding opaque regions at pixel edges to 4μm,crosstalk rates from adjacent pixels could be effectively reduced to approximately 2%,and promising ERs ranging from 17.32 to 27.41 were implemented. 展开更多
关键词 infrared physics infrared polarimetric focal plane array monolithic integration Mercury Cadmium Telluride extinction ratio
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Monolithically Integrated Photonic Structures for Stable On-Chip Solar Blind Communications
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作者 HE Rui HU Qiang +2 位作者 RAN Junxue WANG Junxi WEI Tongbo 《ZTE Communications》 2024年第4期3-8,共6页
A solar-blind multi-quantum well(MQW)structure wafer based on AlGaN materials is epitaxial growth by metal-organic chemical vapor deposition(MOCVD).The monolithically integrated photonic chips including light-emitting... A solar-blind multi-quantum well(MQW)structure wafer based on AlGaN materials is epitaxial growth by metal-organic chemical vapor deposition(MOCVD).The monolithically integrated photonic chips including light-emitting diodes(LEDs),waveguides,and photodetec-tors(PDs)are presented.The results of the finite-difference time-domain(FDTD)simulation confirm the strong light constraint of the wave-guide designed with the triangular structure in the optical coupling region.Furthermore,in virtue of predominant ultraviolet transverse mag-netic(TM)modes,the solar blind optical signal is more conducive to lateral transmission along the waveguide inside the integrated chip.The integrated PDs demonstrate sufficient photosensitivity to the optical signal from the integrated LEDs.When the LEDs are operated at 100 mA current,the photo-to-dark current ratio(PDCR)of the integrated PD is about seven orders of magnitude.The responsivity,specific detectivity,and external quantum efficiency of the integrated self-driven PD are 74.89 A/W,4.22×1013 Jones,and 3.38×104%,respectively.The stable on-chip optical information transmission capability of the monolithically integrated photonic chips confirms the great potential for application in large-scale on-chip optical communication in the future. 展开更多
关键词 monolithically integration photonic chips UVC solar-blind communication
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Monolithic Convex Limiting for Legendre-Gauss-Lobatto Discontinuous Galerkin Spectral-Element Methods
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作者 Andrés M.Rueda-Ramírez Benjamin Bolm +1 位作者 Dmitri Kuzmin Gregor J.Gassner 《Communications on Applied Mathematics and Computation》 EI 2024年第3期1860-1898,共39页
We extend the monolithic convex limiting(MCL)methodology to nodal discontinuous Galerkin spectral-element methods(DGSEMS).The use of Legendre-Gauss-Lobatto(LGL)quadrature endows collocated DGSEM space discretizations ... We extend the monolithic convex limiting(MCL)methodology to nodal discontinuous Galerkin spectral-element methods(DGSEMS).The use of Legendre-Gauss-Lobatto(LGL)quadrature endows collocated DGSEM space discretizations of nonlinear hyperbolic problems with properties that greatly simplify the design of invariant domain-preserving high-resolution schemes.Compared to many other continuous and discontinuous Galerkin method variants,a particular advantage of the LGL spectral operator is the availability of a natural decomposition into a compatible subcellflux discretization.Representing a highorder spatial semi-discretization in terms of intermediate states,we performflux limiting in a manner that keeps these states and the results of Runge-Kutta stages in convex invariant domains.In addition,local bounds may be imposed on scalar quantities of interest.In contrast to limiting approaches based on predictor-corrector algorithms,our MCL procedure for LGL-DGSEM yields nonlinearflux approximations that are independent of the time-step size and can be further modified to enforce entropy stability.To demonstrate the robustness of MCL/DGSEM schemes for the compressible Euler equations,we run simulations for challenging setups featuring strong shocks,steep density gradients,and vortex dominatedflows. 展开更多
关键词 Structure-preserving schemes Subcellflux limiting monolithic convex limiting(MCL) Discontinuous Galerkin spectral-element methods(DGSEMS) Legendre-Gauss-Lobatto(LGL)nodes
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A Monolithic Integrated CMOS Thermal Vacuum Sensor 被引量:2
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作者 张凤田 唐祯安 +1 位作者 汪家奇 余隽 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2008年第6期1103-1107,共5页
The monolithic integrated micro sensor is an important direction in the fields of integrated circuits and micro sensors. In this paper,a monolithic thermal vacuum sensor based on a micro-hotplate (MHP) and operating... The monolithic integrated micro sensor is an important direction in the fields of integrated circuits and micro sensors. In this paper,a monolithic thermal vacuum sensor based on a micro-hotplate (MHP) and operating under constant bias voltage conditions was designed. A new monolithic integrating mode was proposed,in which the dielectric and passiva- tion layers in standard CMOS processes were used as sensor structure layers,gate polysilicon as the sacrificial layer,and the second polysilicon layer as the sensor heating resistor. Then, the fabricating processes were designed and the monolithic thermal vacuum sensor was fabricated with a 0. 6μm mixed signal CMOS process followed by sacrificial layer etching technology. The measurement results show that the fabricated monolithic vacuum sensor can measure the pressure range of 2- 10^5 Pa and the output voltage is adjustable. 展开更多
关键词 thermal vacuum sensor monolithic integration CMOS micro hotplate
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RELEASE KINETICS OF MONOLITHIC MATRIX COATED WITH OUTER MEMBRANE SYSTEM 被引量:1
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作者 石巍 张国亮 +1 位作者 张凤宝 刘瑛 《Transactions of Tianjin University》 EI CAS 2001年第1期56-60,共5页
The reservoir-monolithic type of the controlled release systems is investigated currently,however,the existing kinetic model could not describe the release process well because the release kinetics is rather complicat... The reservoir-monolithic type of the controlled release systems is investigated currently,however,the existing kinetic model could not describe the release process well because the release kinetics is rather complicated.In this paper,a simplified release kinetic model for diffusion-controlled monolithic matrix coated with outer membrane systems is proposed and verified by the experimental data of mercaptopurinum release experiment.It shows that the model can well describe the release mechanism (the relative error is under 3%) when drug loading (C d) is above its solubility limit (C s).At the same time,the release characteristics of special cases (D mD f and D mD f) are discussed theoretically.When D mD f the release rate becomes constant,namely,zero order release,and the release rate is independent of the drug membrane.This result provides the theoretical basis for the system of zero order release as well as how to control the release rate and the amount of drug release.When D mD f,the release rate is dependent on the drug release coefficient in the monolithic matrix,solubility and drug loading but independent of the process in the outer membrane,and it is similar to monolithic matrix type. 展开更多
关键词 controlled release DIFFUSION mercaptopurinum monolithic matrix outer membrane
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Strongly Gain Coupled DFB Laser Monolithically Integrated with a Self Alignment Spot Size Converter 被引量:1
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作者 刘国利 王圩 +4 位作者 朱洪亮 张静媛 周帆 汪孝杰 胡小华 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2001年第7期832-836,共5页
A new type strongly gain coupled (GC) DFB laser and a new type self alignment spot size converter (SA SSC) are proposed and successfully fabricated.The strongly GC DFB laser is monolithically integrated with the ... A new type strongly gain coupled (GC) DFB laser and a new type self alignment spot size converter (SA SSC) are proposed and successfully fabricated.The strongly GC DFB laser is monolithically integrated with the SA SSC with three step epitaxies.A high single mode yield and large side mode suppression ratio is obtained from the strongly GC DFB laser.A near circle far field pattern is obtained by using the SA SSC. 展开更多
关键词 strongly gain coupled DFB laser spot size converter monolithic integration
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Monolithic特征标的零点与可解群的导长 被引量:1
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作者 徐海静 张广祥 童殷 《西南大学学报(自然科学版)》 CAS CSCD 北大核心 2008年第6期1-3,共3页
给出了分别满足条件(M1)G的monolithic特征标没有公共的零点;(M2)G的非线性不可约monolithic特征标中最多有两个有公共的零点,的有限群的一个导长的上界.
关键词 monolithic特征标 零点 可解群 导长
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基于双DSP(Digital Signal Processor)结构的有源滤波器检测及控制系统 被引量:3
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作者 孙建军 王晓峰 +2 位作者 汤洪海 查晓明 陈允平 《武汉大学学报(工学版)》 CAS CSCD 北大核心 2001年第3期55-59,共5页
简要介绍了DigitalSignalProcessor(DSP)的发展及其性能特点 ,详细讨论了一种利用双DSP构成的有源滤波器检测及控制系统的实现和基本结构及算法 .
关键词 有源滤波器 灵活电力系统 数字信号 单片机 控制系统
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Monolithic特征标的核-余-次数对群结构的影响
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作者 邹国成 李木华 +1 位作者 任永才 罗驰 《西南师范大学学报(自然科学版)》 CAS CSCD 北大核心 2005年第6期1000-1004,共5页
正整数|G:Ker(χ)|/χ(1)叫作不可约特征标χ的核-余-次数.考察了不可约特征标或Monolithic特征标的核-余-次数的算术结构对群的结构的影响.
关键词 monolithic特征标 核-余-次数 超可解群 SYLOW塔
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Co-Design of Monolithically Integrated Photo-Detector and Optical-Receiver
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作者 高鹏 陈弘达 +3 位作者 毛陆虹 贾九春 陈永权 孙增辉 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2004年第2期133-137,共5页
A behavioral model of the photodiode is presented.The model describes the relationship between photocurrent and incident optical power,and it also illustrates the impact of the reverse bias to the variation of the jun... A behavioral model of the photodiode is presented.The model describes the relationship between photocurrent and incident optical power,and it also illustrates the impact of the reverse bias to the variation of the junction capacitance.According to this model,the photodiode and a CMOS receiver circuit are simulated and designed simultaneously under a universal circuit simulation environment. 展开更多
关键词 monolithically integrated CO-DESIGN behavioral model
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一种用于Multi-Processor测量系统的NOC结构的路由节点设计及性能评估 被引量:1
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作者 武畅 李玉柏 彭启琮 《电子测量与仪器学报》 CSCD 2008年第5期101-106,共6页
本文提出了一种用于多处理器(Multi-Processor)测量系统的NOC结构的路由节点的微结构,并详细描述了路由节点的各个部分结构及其各自功能。为了说明本文提出的结构的可行性和实用性,本文设计了一套以DSP和FPGA为基础的用于NOC结构仿真的... 本文提出了一种用于多处理器(Multi-Processor)测量系统的NOC结构的路由节点的微结构,并详细描述了路由节点的各个部分结构及其各自功能。为了说明本文提出的结构的可行性和实用性,本文设计了一套以DSP和FPGA为基础的用于NOC结构仿真的硬件平台,评估了路由节点的资源消耗。最后,本文通过16个路由节点建立了一个基于4×4Mesh拓扑结构的NOC。通过仿真,得到了该网络在不同通信模式下的不同注入率情况下的延时、吞吐率、和面积消耗等性能,并与采用输出缓冲的路由节点进行了比较。同时,针对VOQ(virtual output queue)和输出缓冲大小这两个影响网络性能的重要微结构参数,给出了比较和分析结果。 展开更多
关键词 NOC 路由节点 微结构 多处理器 仿真
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Monolithically Integrated Optoelectronic Receivers Implemented in 0.25μm MS/RF CMOS
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作者 陈弘达 高鹏 +1 位作者 毛陆虹 黄家乐 《Journal of Semiconductors》 EI CAS CSCD 北大核心 2006年第2期323-327,共5页
A monolithically integrated optoelectronic receiver is presented. A silicon-based photo-diode and receiver circuits are integrated on identical substrates in order to eliminate the parasitics induced by hybrid packagi... A monolithically integrated optoelectronic receiver is presented. A silicon-based photo-diode and receiver circuits are integrated on identical substrates in order to eliminate the parasitics induced by hybrid packaging. Implemented in the present deep sub-micron MS/RF (mixed signal, radio frequency) CMOS,this monolithically OEIC takes advantage of several new features to improve the performance of the photo-diode and eventually the whole OEIC. 展开更多
关键词 monolithically integrated OEIC CMOS process
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2.5 Gbit/s monolithic ICs for optical fiber transmitter and receiver in 0.35 μm CMOS process
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作者 冯军 王志功 +5 位作者 王欢 李连鸣 黄璐 盛志伟 章丽 熊明珍 《Journal of Southeast University(English Edition)》 EI CAS 2005年第3期268-271,共4页
2.5 Gbit/s monolithic integrated circuits (ICs) for optical fiber transmitter and receiver in 0.35 μm CMOS (complementary metal-oxide-semiconductor transistor) process are presented. The transmitter, which includ... 2.5 Gbit/s monolithic integrated circuits (ICs) for optical fiber transmitter and receiver in 0.35 μm CMOS (complementary metal-oxide-semiconductor transistor) process are presented. The transmitter, which includes a 4: 1 multiplexer and a laser diode driver (LDD), has four 622 Mbit/s random signals as its inputs and gets a 2.5 Gbit/s driving signal as its output; the receiver detects a 2.5 Gbit/s random signal and gets four 622 Mbit/s signals at the output. The main circuits include a trans-impedance amplifier (TIA), a limiting amplifier, a clock and data recovery (CDR) unit, and a 1: 4 demultiplexer (DEMUX). Test results prove the logic functions of the transmitter to be right, and the 10% to 90% rise and fall times of transmitter's output data eye diagram are 211.1 ps and 200 ps, respectively. The sensitivity of the receiver is measured to be better than 20 mV. The root mean square jitter of the DEMUX's output data is 15.6 ps and that of the clock after 1: 4 frequency dividing is 1.9 ps. Two chips are both applicable to 2.5 Gbit/s optical fiber communication systems. 展开更多
关键词 optical fiber communication monolithic transmitter RECEIVER
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MATHEMATICAL ANALYSIS OF DRUG RELEASE FROM A MONOLITHIC MATRIX WITH AN INITIALLY LINEAR CONCENTRATION DISTRIBUTION
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作者 徐铜文 张国亮 +2 位作者 张凤宝 王淑兰 王绍亭 《Transactions of Tianjin University》 EI CAS 1997年第2期82-87,共6页
Based on the principle of chemical engineering in the multisubject field—drug delivery, the release kinetics of the slab monolithic matrix with an initially linear concentration distribution is studied in this paper.... Based on the principle of chemical engineering in the multisubject field—drug delivery, the release kinetics of the slab monolithic matrix with an initially linear concentration distribution is studied in this paper. It can be used to describe the later stage when drug loading is above its solubility limit. A comprehensive model is proposed and the generalized solutions are acquired by Laplace transformation, from which a special case, i.e. a perfect sink has been deduced. According to the derived equations, the concentration profiles in the matrix has been computed and illustrated and the effect of volume of extraction medium on release has been investigated. 展开更多
关键词 monolithic matrix modelling controlled release diffusion linear concentration distribution Laplace transformation
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