BACKGROUND The gram-negative aerobic bacterium Moraxella osloensis is an opportunistic pathogen in brain tissues.CASE SUMMARY The gram-negative aerobic bacterium Moraxella osloensis was isolated from a patient’s brai...BACKGROUND The gram-negative aerobic bacterium Moraxella osloensis is an opportunistic pathogen in brain tissues.CASE SUMMARY The gram-negative aerobic bacterium Moraxella osloensis was isolated from a patient’s brain tissue during a stereotactic biopsy.CONCLUSION This is the first report of a brain tissue infection with Moraxella osloensis possibly causing brain gliomatosis.展开更多
Objective:To determine the antimoraxella activity of Ethiopian medicinal plants extracts. Methods:Two clinical isolates of Moraxella cattarhalis(M.cattarhalis) with different antibiotic sensitivity pattern were tested...Objective:To determine the antimoraxella activity of Ethiopian medicinal plants extracts. Methods:Two clinical isolates of Moraxella cattarhalis(M.cattarhalis) with different antibiotic sensitivity pattern were tested to determine their susceptibility to garlic[Allium sativum(A. sativum)],bark of cinnamon[Cinnamomum zeylanicum(C.zeylanicum)],clove[Syzygium aromaticum(S.aromaticum)],and leaves of avocado[Persea americana(P.americana)], rosemary[Rosmarinus of ficinalis(R.of ficinalis)]and prickly poppy[Argemone mexicana(A. mexicana)].Disk diffusion assay and broth dilution method were used to measure zone of inhibition,minimum inhibitory concentration(MIC) and minimum bactericidal concentration (MBC) of plant extracts against M.cattarhalis.Results:Both the strains of M.cattarhalis exhibited similar sensitivities to the extracts of medicinal plants.Antimoraxella activity was exhibited only by garlic,avocado leaves and cinnamon.Garlic was found to be more antagonistic to M.cattarhalis than cinnamon and avocado.Garlic and avocado leaves have shown similar MIC(30 mg/mL) where as their zone of inhibition(15 and 11 mm,respectively) were different. Conclusions:Garlic,cinnamon and avocado leaves extracts represents alternative source of natural antimicrobial substances for use in clinical practice for the treatment of cases of M. cattarhalis.Further research on the effects of these extracts on M.cattarhalis can be rewarding to pursue in the search for new broad spectrum antimicrobial agents.展开更多
A medium was developed to support the anaerobic growth and antimicrobial susceptibility testing of clinical Moraxella catarrhalis isolates. The MICs of clinical Moraxella catarrhalis isolates under anaerobic condition...A medium was developed to support the anaerobic growth and antimicrobial susceptibility testing of clinical Moraxella catarrhalis isolates. The MICs of clinical Moraxella catarrhalis isolates under anaerobic conditions were, in general, decreased as compared to atmospheric or capnophilic conditions, while the MBCs for all conditions were within a 2 fold concentration dilution. Biofilm formation was affected by the presence of sub-MIC concentrations of azithromycin and the tested quinolones with the exception of levofloxacin.展开更多
Keratoconjunctivitis in sheep causes severe ocular irritation thereby reducing the production performance thus causing economic loss to the farmers. Bacterial cause of keratoconjunctivitis in sheep may be due to Liste...Keratoconjunctivitis in sheep causes severe ocular irritation thereby reducing the production performance thus causing economic loss to the farmers. Bacterial cause of keratoconjunctivitis in sheep may be due to Listeria monocytogenes, Moraxella ovis, Mycoplasma conjunctivae, etc. An investigation carried out at Tirupathur, Sivagangai district, Tamil Nadu, India revealed keratoconjunctivitis in sheep (population 100 animals). Isolation and identification of eye swabs from ailing animals (n = 5) showed that the bacteria was Moraxella sp. Polymerase chain reaction (PCR) of the isolate was positive for Moraxella sp. Antimicrobial sensitivity testing of the isolate showed that it was sensitive to all antibiotics used in the study. This study reports the presence of Moraxella sp. infection in sheep warranting further studies to know the exact status of this organism so as to prevent keratoconjunctivitis in sheep.展开更多
文摘BACKGROUND The gram-negative aerobic bacterium Moraxella osloensis is an opportunistic pathogen in brain tissues.CASE SUMMARY The gram-negative aerobic bacterium Moraxella osloensis was isolated from a patient’s brain tissue during a stereotactic biopsy.CONCLUSION This is the first report of a brain tissue infection with Moraxella osloensis possibly causing brain gliomatosis.
文摘Objective:To determine the antimoraxella activity of Ethiopian medicinal plants extracts. Methods:Two clinical isolates of Moraxella cattarhalis(M.cattarhalis) with different antibiotic sensitivity pattern were tested to determine their susceptibility to garlic[Allium sativum(A. sativum)],bark of cinnamon[Cinnamomum zeylanicum(C.zeylanicum)],clove[Syzygium aromaticum(S.aromaticum)],and leaves of avocado[Persea americana(P.americana)], rosemary[Rosmarinus of ficinalis(R.of ficinalis)]and prickly poppy[Argemone mexicana(A. mexicana)].Disk diffusion assay and broth dilution method were used to measure zone of inhibition,minimum inhibitory concentration(MIC) and minimum bactericidal concentration (MBC) of plant extracts against M.cattarhalis.Results:Both the strains of M.cattarhalis exhibited similar sensitivities to the extracts of medicinal plants.Antimoraxella activity was exhibited only by garlic,avocado leaves and cinnamon.Garlic was found to be more antagonistic to M.cattarhalis than cinnamon and avocado.Garlic and avocado leaves have shown similar MIC(30 mg/mL) where as their zone of inhibition(15 and 11 mm,respectively) were different. Conclusions:Garlic,cinnamon and avocado leaves extracts represents alternative source of natural antimicrobial substances for use in clinical practice for the treatment of cases of M. cattarhalis.Further research on the effects of these extracts on M.cattarhalis can be rewarding to pursue in the search for new broad spectrum antimicrobial agents.
文摘A medium was developed to support the anaerobic growth and antimicrobial susceptibility testing of clinical Moraxella catarrhalis isolates. The MICs of clinical Moraxella catarrhalis isolates under anaerobic conditions were, in general, decreased as compared to atmospheric or capnophilic conditions, while the MBCs for all conditions were within a 2 fold concentration dilution. Biofilm formation was affected by the presence of sub-MIC concentrations of azithromycin and the tested quinolones with the exception of levofloxacin.
文摘Keratoconjunctivitis in sheep causes severe ocular irritation thereby reducing the production performance thus causing economic loss to the farmers. Bacterial cause of keratoconjunctivitis in sheep may be due to Listeria monocytogenes, Moraxella ovis, Mycoplasma conjunctivae, etc. An investigation carried out at Tirupathur, Sivagangai district, Tamil Nadu, India revealed keratoconjunctivitis in sheep (population 100 animals). Isolation and identification of eye swabs from ailing animals (n = 5) showed that the bacteria was Moraxella sp. Polymerase chain reaction (PCR) of the isolate was positive for Moraxella sp. Antimicrobial sensitivity testing of the isolate showed that it was sensitive to all antibiotics used in the study. This study reports the presence of Moraxella sp. infection in sheep warranting further studies to know the exact status of this organism so as to prevent keratoconjunctivitis in sheep.