On the basis the elementary theory of supply chain management,the features and problems in the supply-chain management of flowers in Yunnan Province are analyzed.The problems include poor image of flowers caused by lo...On the basis the elementary theory of supply chain management,the features and problems in the supply-chain management of flowers in Yunnan Province are analyzed.The problems include poor image of flowers caused by low-end package,imperfect supply-chain structure,and weak processing section after harvesting flowers,hard to launch the cold chain transportation and inadequate awareness of enterprises on consumers.The countermeasures are put forward,which include perfecting various kinds of supply chain structure;intensifying the information system management of flowers in Yunnan Province;developing the cold chain logistics and cultivating and supporting the third-party logistics of flower industry in Yunnan Province.展开更多
BACKGROUND Inpatient telemetry heart rhythm monitoring overuse has been linked to higher healthcare costs.AIM To evaluate if CHA2DS2-VASc score could be used to indicate if a patient admitted with possible cerebrovasc...BACKGROUND Inpatient telemetry heart rhythm monitoring overuse has been linked to higher healthcare costs.AIM To evaluate if CHA2DS2-VASc score could be used to indicate if a patient admitted with possible cerebrovascular accident(CVA)or transient ischemic attack(TIA)requires inpatient telemetry monitoring.METHODS A total of 257 patients presenting with CVA or TIA and placed on telemetry monitoring were analyzed retrospectively.We investigated the utility of telemetry monitoring to diagnose atrial fibrillation/flutter and the CHA2DS2-VASc scoring tool to stratify the risk of having CVA/TIA in these patients.RESULTS In our study population,63(24.5%)of the patients with CVA/TIA and telemetry monitoring were determined to have no ischemic neurologic event.Of the 194(75.5)patients that had a confirmed CVA/TIA,only 6(2.3%)had an arrhythmia detected during their inpatient telemetry monitoring period.Individuals with a confirmed CVA/TIA had a statistically significant higher CHA2DS2-VASc score compared to individuals without an ischemic event(3.59 vs 2.61,P<0.001).CONCLUSION Given the low percentage of inpatient arrhythmias identified,further research should focus on discretionary use of inpatient telemetry on higher risk patients to diagnose the arrhythmias commonly leading to CVA/TIA.A prospective study assessing event rate of CVA/TIA in patients with higher CHA2DS2-VASc score should be performed to validate the CHA2DS2-VASc score as a possible risk stratifying tool for patients at risk for CVA/TIA.展开更多
文摘On the basis the elementary theory of supply chain management,the features and problems in the supply-chain management of flowers in Yunnan Province are analyzed.The problems include poor image of flowers caused by low-end package,imperfect supply-chain structure,and weak processing section after harvesting flowers,hard to launch the cold chain transportation and inadequate awareness of enterprises on consumers.The countermeasures are put forward,which include perfecting various kinds of supply chain structure;intensifying the information system management of flowers in Yunnan Province;developing the cold chain logistics and cultivating and supporting the third-party logistics of flower industry in Yunnan Province.
基金Financial supported by the National Natural Science Foundation of China (Grant No.81673872and 81460659)Department of Education Guangdong of Province (Grant No. YQ2013043)Department of Science and Technology of Tibet autonomous region (Grant No.2016ZR-ZY-01).
文摘目的:对小儿七星茶的主要化学成分进行解析和鉴定,并探讨其治疗小儿消化不良的作用机制。方法:采用UPLC-QTOF/MS技术对小儿七星茶进行测定分析。通过数据库搜索化学成分相关靶点和疾病相关靶点,并筛选出小儿七星茶对应的疾病治疗靶点。运用Cytoscape软件进行网络建立和分析,同时将成分和靶点根据药材来源进行归类,通过靶点数目分布验证组方的“君、臣、佐、使”配伍规律。运用ClueGo进行GO生物功能分析和KEGG通路富集,进一步预测小儿七星茶发挥药效的作用机制。结果:通过解析得到5 3 个化合物,筛选出疾病相关靶点6 3 个,其中AKT1、FOS、SLC6A4、COM T和5-H T受体是重要靶点,能调节碳水化合物消化吸收、5-H T代谢和cA M P等信号通路。结果表明,小儿七星茶能通过干预脑肠轴相关的靶点和通路发挥治疗作用。结论:本研究为小儿七星茶的深入研究提供了实验和理论基础,为中药复方的药效学机制研究提供了科学依据。
文摘BACKGROUND Inpatient telemetry heart rhythm monitoring overuse has been linked to higher healthcare costs.AIM To evaluate if CHA2DS2-VASc score could be used to indicate if a patient admitted with possible cerebrovascular accident(CVA)or transient ischemic attack(TIA)requires inpatient telemetry monitoring.METHODS A total of 257 patients presenting with CVA or TIA and placed on telemetry monitoring were analyzed retrospectively.We investigated the utility of telemetry monitoring to diagnose atrial fibrillation/flutter and the CHA2DS2-VASc scoring tool to stratify the risk of having CVA/TIA in these patients.RESULTS In our study population,63(24.5%)of the patients with CVA/TIA and telemetry monitoring were determined to have no ischemic neurologic event.Of the 194(75.5)patients that had a confirmed CVA/TIA,only 6(2.3%)had an arrhythmia detected during their inpatient telemetry monitoring period.Individuals with a confirmed CVA/TIA had a statistically significant higher CHA2DS2-VASc score compared to individuals without an ischemic event(3.59 vs 2.61,P<0.001).CONCLUSION Given the low percentage of inpatient arrhythmias identified,further research should focus on discretionary use of inpatient telemetry on higher risk patients to diagnose the arrhythmias commonly leading to CVA/TIA.A prospective study assessing event rate of CVA/TIA in patients with higher CHA2DS2-VASc score should be performed to validate the CHA2DS2-VASc score as a possible risk stratifying tool for patients at risk for CVA/TIA.
