Tracking direct and indirect impact on technology and policy of transformative research via ego citation network

Purpose:The disseminating of academic knowledge to nonacademic audiences partly relies on the transition of subsequent citing papers.This study aims to investigate direct and indirect impact on technology and policy originating from transformative research based on ego citation network.Design/methodology/approach:Key Nobel Prize-winning publications(NPs)in fields of gene engineering and astrophysics are regarded as a proxy for transformative research.In this contribution,we introduce a network-structural indicator of citing patents to measure technological impact of a target article and use policy citations as a preliminary tool for policy impact.Findings:The results show that the impact on technology and policy of NPs are higher than that of their subsequent citation generations in gene engineering but not in astrophysics.Research limitations:The selection of Nobel Prizes is not balanced and the database used in this study,Dimensions,suffers from incompleteness and inaccuracy of citation links.Practical implications:Our findings provide useful clues to better understand the characteristics of transformative research in technological and policy impact.Originality/value:This study proposes a new framework to explore the direct and indirect impact on technology and policy originating from transformative research.

Research on the Digital Economy,Technological Innovation,and Transformation and Upgrading of the Manufacturing Industry in Shandong Province

Based on panel data from 16 cities in Shandong Province from 2013 to 2022,and grounded in theoretical analysis,this paper constructs a benchmark regression model,a mediating effect model,and a heterogeneity test for empirical analysis.The results show that:(1)the digital economy has a significant positive effect on promoting the transformation and upgrading of the manufacturing industry in Shandong Province;(2)the digital economy can drive the transformation and upgrading of the manufacturing industry through technological innovation;and(3)the impact of the digital economy on the transformation and upgrading of the manufacturing industry in Shandong Province is evidently heterogeneous.

Degradation of FAK-targeting by proteolytic targeting chimera technology to inhibit the metastasis of hepatocellular carcinoma

Liver cancer is a prevalent malignant cancer,ranking third in terms of mortality rate.Metastasis and recurrence primarily contribute to the high mortality rate of liver cancer.Hepatocellular carcinoma(HCC)has low expression of focal adhesion kinase(FAK),which increases the risk of metastasis and recurrence.Nevertheless,the efficacy of FAK phosphorylation inhibitors is currently limited.Thus,investigating the mechanisms by which FAK affects HCC metastasis to develop targeted therapies for FAK may present a novel strategy to inhibit HCC metastasis.This study examined the correlation between FAK expression and the prognosis of HCC.Additionally,we explored the impact of FAK degradation on HCC metastasis through wound healing experiments,transwell invasion experiments,and a xenograft tumor model.The expression of proteins related to epithelial-mesenchymal transition(EMT)was measured to elucidate the underlying mechanisms.The results showed that FAK PROTAC can degrade FAK,inhibit the migration and invasion of HCC cells in vitro,and notably decrease the lung metastasis of HCC in vivo.Increased expression of E-cadherin and decreased expression of vimentin indicated that EMT was inhibited.Consequently,degradation of FAK through FAK PROTAC effectively suppressed liver cancer metastasis,holding significant clinical implications for treating liver cancer and developing innovative anti-neoplastic drugs.

Revolutionizing Healthcare—The Integration of Virtual Worlds, AR, and Metaverse Technology

This paper explores the transformative impact of virtual worlds, augmented reality (AR), and the metaverse in the healthcare sector. It delves into the ways these technologies are reshaping patient care, medical education, and research, while also addressing the challenges and opportunities they present. The paper highlights the potential benefits of these technologies and emphasizes the need for comprehensive regulatory frameworks and ethical guidelines to ensure responsible integration. Finally it outlines their transformative impact and discusses the challenges and opportunities they present for the future of healthcare provision.

A Deep Dive into the Trajectory and Transformation of Fintech in Colombia Through the Case of PTM Colombia-A Secondary Publication

This research focuses on analyzing and understanding the evolution and impact of fintech companies in Colombia,using PTM Colombia as a case study,a company that has undergone a significant transformation from its beginnings as a provider of physical recharges to its current position.as a comprehensive platform for digital financial services.The current research uses a qualitative descriptive approach and emphasizes understanding the perceptions and experiences in the field of Fintech in Colombia,particularly in the case of PTM Colombia.The study revealed that adaptability and customer orientation have been fundamental in the evolution of PTM,allowing the company to expand its range of services by actively listening to the needs of its users and adjusting its strategies accordingly.In addition,an accelerated and diversified growth of Fintech will be observed in Colombia,particularly in sectors such as credit and payments,driven by a constantly advancing technological environment and a regulatory framework that,although it presents challenges,also offers opportunities for financial innovation.This growth has impacted the traditional banking sector,which,instead of being replaced by Fintech,is finding new forms of collaboration and coexistence that benefit both parties and,above all,the end consumer.In conclusion,the study highlights how Fintech in Colombia,represented by cases such as PTM,is redefining the financial landscape through the adoption of advanced technologies,collaboration with traditional banking,and strong customer orientation.

Science and Technology Backyard: A novel model for technology innovation and agriculture transformation towards sustainable intensification

Science and Technology Backyard(STB) is an integrated platform for technology innovation, knowledge transfer, people training and agricultural transformation towards sustainable intensification. STB professors, graduate students and extension workers lived and worked together with smallholder farmers in rural areas.

Research Progress of On-line Monitoring Technology for Electromagnetic Environment of Power Transmission and Transformation Projects

Based on the collection of relevant literature and cases,the research and application status of on-line monitoring technology for electromagnetic environment of power transmission and transformation projects at home and abroad were introduced.Moreover,the problems existing in the on-line monitoring of electromagnetic environment were expounded,and the development prospect was forecasted.

Tetracycline-Based Binary Ti Vectors pLSU with Efficient Cloning by the Gateway Technology for <i>Agrobacterium tumefaciens</i>-Mediated Transformation of Higher Plants

We constructed small high-yielding binary Ti vectors with a bacterial tetracycline resistance gene to facilitate efficient cloning afforded by the Gateway Technology (Invitrogen) for Agrobacterium tumefaciens-mediated transformation of higher plants. The Gateway Technology vectors are kanamycin-based, thus tetracycline-based destination and expression vectors are easily selected for the antibiotic resistance in the Escherichia coli media. We reduced the size of the tetracycline resistance gene TetC from pBR322 to 1468 bp containing 1191 bp of the coding region, 93 bp of 5’-upstream, and 184 bp 3’-downstream region. The final size of binary Ti vector skeleton pLSU11 is 5034 bp. pLSU12 and 13 have the kanamycin resistance NPTII gene as a plant-selectable marker. pLSU13?and 15 contain the hygromycin resistance HPH gene as a selection marker. pLSU13 and 15 also have the β-glucuronidase (GUS) reporter gene in addition to the plant selection marker. We also constructed a mobilizable version of tetracycline-based binary Ti vector pLSU16 in which the mob function of ColE1 replicon was maintained for mobilization of the binary vector from E. coli to A. tumefaciens by tri-parental mating. The final size of binary Ti vector skeleton pLSU16 is 5580 bp. New tetracycline- based binary Ti vectors pLSU12 were found as effective as kanamycin-based vector pLSU2 in promoting a 10-fold increase in fresh weight yield of kanamycin-resistant calli after A. tumefaciens-mediated transformation of tobacco leaf discs. Using the Gateway Technology we introduced the plant-expressible GUSgene to the T-DNA of binary Ti vector pLSU12. Expression of the β-glucuronidase enzyme activity was demonstrated by histochemical staining of the GUS activity in transformed tobacco leaf discs.

What Drives China’s Transformational Growth:Technology,Efficiency or Factor Cost?

With rising costs of capital, labor and energy, cost efficiency and cost management have become important questions confronting the next stage of China＇s economic growth. By building a parametric cost frontier model using panel data, this paper investigates the drivers of economic growth transformation from a cost perspective. According to our research, among various effects triggering corporate cost variations and in addition to the expansion of production scale, the largest effect is from technological progress, followed by the effect of factor price adjustment and the effect of efficiency gains. Within the decomposition of factor price adjustment effect, the energy factor effect is the most significant. Furthermore, energy price fluctuations are likely to become major factors restricting saving-based growth. Further study reveals that both the ownership reform and opening up of SOEs are favorable to reducing the costs generated by inefficiency. This paper provides empirical evidence for the driving mechanism of saving-based growth transformation as well as empirical evidence to support to the further deepening of property rights and market-oriented reforms.

Transformation of Modern Chinese Architectural Form and Its Influence on the Protection of Contemporary Chinese Architectural Heritage

Architecture is a fascinating and complex mixture of cultural practices.Different cultures are intertwined to form a new system.The relationship between Chinese native architecture and Western construction methods in the development of Chinese construction from 1840 to 1937 is inspected.Based on Chinese and British sources,special attention is paid to building materials and different aspects of the building process.The research shows that the complex interaction in shaping Chinese architecture has led to a new style and a new construction method,which combines the characteristics of two systems in material supply and use,construction technology,builder organization,tools used and the education received.In the construction and protection related to integration and conflict,the development of contemporary China's emerging construction protection industry is similar to the history of modern Chinese architecture.

Design Index and Empirical Analysis of the Evaluation Index System for the Transformation of Scientific and Technological Achievements of Universities in Beijing, Tianjin and Hebei

Promoting the transformation of scientific and technological achievements of universities and colleges in Beijing, Tianjin, and Hebei is an important measure to enhance the level of scientific and technological development in universities, enhance the scientific and technological synergy of Beijing-Tianjiii-Hebei urban agglomeration, practice the coordinated development strategy of Beijing, Tianjin and Hebei, and promote the construction of Xiong'an New District. Based on the scientific and technological input of colleges and universities, the development of science and technology and the output of science and technology, this paper uses Delphi and AHP to construct a Beijing, Tianjin, Hebei University Science and Technology Achievement Transformation Performance Evaluation System from the perspectives of transformation potentials, scientific research activities and achievements transformation of university scientific and technological achievements. An empirical analysis was carried out to provide reference for the government's efficient decision-making and improvement of strategies for transforming scientific and technological achievements in universities.

Coupling effect on the thermal hazard assessment of hazardous chemical materials via calorimetric technologies and simulation approaches

The coupling effect of heat absorption and release exists in the thermal decomposition of a few chemical materials.However,the impact of the above coupling on thermal hazard assessment is not considered in the literature studies.In this work,nitroguanidine(NQ)and 1,3,5-trinitro-1,3,5-triazine(RDX)are selected as representative materials to explore the influence of the coupling effect on the thermal hazard assessment of chemical materials.The linear heating experiments of NQ and RDX are carried out by a microcalorimeter and synchronous thermal analyser.The thermal decomposition curves are decoupled by advanced thermokinetics software.The thermal decomposition and kinetic parameters before and after decoupling are calculated.The results of TG experiment show that both NQ and RDX began to lose mass during the endothermic stage.The endothermic melting and exothermic decomposition of NQ and RDX are coupled within this stage.The coupling effect has different degrees of influence on its initial decomposition temperature and safety parameters.Compared with the parameters in the coupling state,the initial decomposition temperature and adiabatic induction period after decoupling decrease.The self-accelerating decomposition temperature increases,and internal thermal runaway time decreases.In the thermal hazard assessment of chemical materials with coupling effects,the calculated parameters after decoupling should be taken as an important safety index。

Digital Transformation, Market Competition, and Corporate Green Technology Innovation

This paper selects China's A-share listed companies from 2012 to 2021 as the research sample and explores the impact of digital transformation on corporate green technology innovation and the moderating role of corporate competitive position in this relationship.The research findings are as follows:Digital transformation plays a significant role in promoting corporate green technology innovation.The improvement of corporate competitive position weakens the promoting effect of digital transformation on corporate green technology innovation.The moderating effect of the corporate competition position is more pronounced in the enterprises of the eastern and western regions,as well as in the listed companies in the manufacturing industry.The promoting effect of digital transformation on utility model patent innovation is dramatically attenuated when the corporate competitive position is strengthened.However,the weakening effect on invention patent innovation is not statistically significant.

Digital Transformation and Green Technology Innovation in Manufacturing Enterprises: A Study Based on Big Data Text Mining

Digital transformation serves as a new driving force and engine for enterprise innovation.Meanwhile,the national strategy of carbon peaking and carbon neutrality has set new goals and requirements for the green development of the Chinese manufacturing industry.From the three-dimensional perspective of"strategy-resource-institution,"this paper explores the impact and mechanism of digital transformation on green technology innovation of Chinese manufacturing enterprises and the heterogeneous impact of the institutional logic of ownership structure.Using a sample of 1,016 A-share listed manufacturing companies on the Shanghai and Shenzhen Stock Exchanges from 2011 to 2019 and based on big data text mining and a negative binomial regression model,this study finds that:(1)Digital strategy significantly enhances green technology innovation capability of enterprises;(2)digital resource investment partially mediates the effect of digital strategy on the enhancement of green technology innovation capability;and(3)the ownership structure of enterprises plays a moderating role in the mediating relationship mentioned above.Specifically,compared to state-owned enterprises(SOEs),non-state-owned enterprises(NsOEs)show no significant difference in the stages where digital strategy promotes green technology innovation and guides digital resource investment.However,they demonstrate higher efficiency in transforming digital resource investment into green technology innovation.The robustness test indicates that the significant effect of digital strategy and resource investment on green technology innovation in enterprises remains valid in the medium term,with a continuous enabling effect.There is no significant difference between SOEs and NsOEs in the medium and long term in promoting green technology innovation through digital transformation.Further,introducing keyword text networks to explore the structural impact of digital strategy,this study finds that digital product and manufacturing strategy are adequate strategic dimensions to enhance green technology innovation capability,and digital financial strategy and digital marketing strategy have no direct promoting effect on green technology innovation of enterprises.From the perspectives of strategies,resources,and institutions,the research findings elucidate the process mechanisms of digital acceleration in the green transformation of manufacturing and the heterogeneous effect of ownership structure and provide critical theoretical insights into the role mechanisms and contextual factors of digitalization on green innovation in manufacturing enterprises.Moreover,this study offers scientific decision-making support for incentivizing the manufacturing industry to seize the opportunities of industrial digitalization and accelerate carbon peaking and carbon neutrality.

Coupling Relationship Among Technological Innovation,Industrial Transformation and Environmental Efficiency:A Case Study of the Huaihai Economic Zone,China

The 14th Five-Year Plan period is a critical period for China to achieve high-quality development. Based on super-efficiency slacks-based measure(SBM) model, grey-related analysis(GRA) and other models, this paper studies the heterogeneity of the coupling relationship among technological innovation, industrial transformation and environmental efficiency in the Huaihai Economic Zone during the period of 2005-2019. In addition, it analyzes the coupling mechanism of single and binary systems to the ternary system, which is of great significance for the collaborative symbiosis among systems. The findings are as follows. 1) The technological innovation, industrial transformation and environmental efficiency(TIE) systems of the Huaihai Economic Zone had significant spatial-temporal heterogeneity. Although their evaluation value fluctuated, the development trends are all positive. Ultimately, technological innovation is characterized by being high in the northeast and low in the southwest around Xuzhou, while other systems are relatively staggered in space. 2) The coupling of TIE systems is in transition, lack of orderly integration and benign interaction. However, the developing trend of interaction is also upward, and a spatial pattern driven by Xuzhou and Linyi as the dual cores has gradually formed. Moreover, the coupling is mostly manifested as outdated technological innovation and industrial transformation. Except for the final coordination of regenerative cities, the other resource types are all in transition. Cities in all traffic locations are still in transition. The overall system interaction of cities on Longhai Line(Lanzhou-Lianyungang Railway) is relatively optimal, and cities on Xinshi Line(Xinxiang-Rizhao Railway) are accelerating toward synergy. 3) The coupling status of TIE systems depends on the development of the single system and the interaction of the binary(2E) system. The coupling is closely related to technological innovation and Technology-Industry system,and is hindered by the inefficient interaction of Technology-Environment system. Specifically, the synergy of regenerative cities is attributed to the advantage of a single system and the effective integration of 2E systems. Beneficial from the advantages of environmental efficiency, the cities on Xinshi Line promote the synergy of the 2E and TIE systems. Therefore, while the Huaihai Economic Zone stimulates the development potential of the single and 2E systems, it is necessary to amplify the superimposition effect of systems in accordance on the basis of resource and location.

Research on the Mode of ESP Course under the Background of the Application of Technological Transformation

In this paper, we conduct research on the mode of ESP course under the background of the application of technological transformation. To cater to the needs of the development of the college students’ vocational students’ English level high starting point of key university fi rst opened the ESP courses. Applied undergraduate colleges and universities is not to be outdone that after students fi nish college English courses opened a professional English and bilingual courses. However, the current ESP teaching in China is not yet mature that mainly displays in: goal is not clear, backward teaching mode, teaching method of the single insufficient standard, teaching material development. Therefore, this paper proposes the countermeasures and suggestions for systematic optimization.

Theoretical Model on Transformation Factors of Scientific and Technological Achievements under the Belt and Road Initiative

With the continuous deepening of the Belt and Road Initiative,the countries involved are increasingly connected in the field of science and technology.Based on the transformation theory of scientific and technological(S&T)achievements,this study establishes a theoretical model of transformation factors of S&T achievements under the Belt and Road Initiative.Combined with the data analysis from questionnaire,it is found that in S&T achievements transformation process,there is a significant positive correlation between the innovation factors and the transfer factors,between the transfer factors and the diffusion factors,and between the diffusion factors and the transformation results.These conclusions provide reference for the subsequent S&T achievements transformation activities under the Belt and Road Initiative.Therefore,in the process of promoting the transformation of S&T achievements under the Belt and Road Initiative in the future,innovation factors such as information innovation,service innovation,and cooperative innovation should be fully reflected.Relevant agencies should take the transfer factors of S&T achievements as guidance;promote and apply the results of incubation through diffusion media and diffusion channels.

Transformer网络技术在电池储能管理中的应用与优化

电池储能管理系统在现代能源网络中起关键性的作用。随着对能源效率和储能系统可靠性的要求日益提升,深度学习技术在电池储能管理中的应用受到了广泛关注。本文旨在探讨Transformer网络技术在电池储能管理中的创新应用与优化策略。首先,本文介绍了电池储能管理系统的基本概念和现阶段面临的主要挑战。然后全面分析了深度学习技术在电池储能管理中的应用现状,着重讨论了各种网络模型的性能及其在实际应用中的成效,并提出了一种基于Transformer架构优化的电池储能管理策略,该方法在提升系统稳定性方面的显著优势。本文的研究不仅为电池储能管理提供了新的技术手段,也为未来相关技术的进一步发展提供了理论支持和实践参考。

基于Transformer技术的机器翻译设计与开发

在语言翻译中,一般的人工翻译存在翻译反应时间长的问题,为解决这一问题设计了一款基于Transformer模型的机器翻译应用程序,在传统翻译的基础上,实现更加快速高效、精准翻译的目的。该程序客户端的结构功能设计满足人们对一般翻译程序的需求,通过对翻译语句相似度的计算歧义语句消除,完成了在软件功能上的应用设计,并凭借两者的相互结合实现了在传统翻译基础上的新型机器自动翻译应用程序。对程序的实验测试表明,本程序相较于一般的翻译软件运行效率更高,模型的复杂度更低,同时在翻译速度和准确度方面均有所提高。

Effects of six years of simulated N deposition on gross soil N transformation rates in an old-growth temperate forest

Elevated atmospheric nitrogen(N) deposition has been detected in many regions of China, but its effects on soil N transformation in temperate forest ecosystems are not well known. We therefore simulated N deposition with four levels of N addition rate(N0, N30, N60, and N120) for6 years in an old-growth temperate forest in Xiaoxing’an Mountains in Northeastern China. We measured gross N transformation rates in the laboratory usingN tracing technology to explore the effects of N deposition on soil gross N transformations taking advantage of N deposition soils. No significant differences in gross soil N transformation rates were observed after 6 years of N deposition with various levels of N addition rate. For all N deposition soils, the gross NH~+ immobilization rates were consistently lower than the gross N mineralization rates,leading to net N mineralization. Nitrate(NO~-) was primarily produced via oxidation of NH~+(i.e., autotrophic nitrification), whereas oxidation of organic N(i.e., heterotrophic nitrification) was negligible. Differences between the quantity of ammonia-oxidizing bacteria and ammonia-oxidizing archaea were not significant for any treatment, which likely explains the lack of a significant effect on gross nitrification rates. Gross nitrification rates were much higher than the total NO~- consumption rates,resulting in a build-up of NO~-, which highlights the high risk of N losses via NO~- leaching or gaseous N emissions from soils. This response is opposite that of typical N-limited temperate forests suffering from N deposition,suggesting that the investigated old-growth temperate forest ecosystem is likely to approach N saturation.