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3D Geological Modeling with Multi-source Data Integration in Polymetallic Region:A Case Study of Luanchuan,Henan Province,China 被引量:1
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作者 Gongwen Wang~(1,2),Shouting Zhang~(1,2),Changhai Yan~3,Yaowu Song~3,Limei Wang~1 1.School of Earth Sciences and Resources,China University of Geosciences(Beijing),Beijing 100083,China. 2.State Key laboratory of Geological Processes and Mineral Resources,China University of Geosciences,Beijing 100083,China 3.Henan Institute of Geological Survey,Zhengzhou 450007,China 《地学前缘》 EI CAS CSCD 北大核心 2009年第S1期166-167,共2页
The development of 3D geological models involves the integration of large amounts of geological data,as well as additional accessible proprietary lithological, structural,geochemical,geophysical,and borehole data.Luan... The development of 3D geological models involves the integration of large amounts of geological data,as well as additional accessible proprietary lithological, structural,geochemical,geophysical,and borehole data.Luanchuan,the case study area,southwestern Henan Province,is an important molybdenum-tungsten -lead-zinc polymetallic belt in China. 展开更多
关键词 3D GEOLOGICAL modeling multi-source data MINERAL exploration METALLOGENIC model virtual GEOLOGICAL section Luanchuan POLYMETALLIC REGION
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Multi-source heterogeneous data access management framework and key technologies for electric power Internet of Things
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作者 Pengtian Guo Kai Xiao +1 位作者 Xiaohui Wang Daoxing Li 《Global Energy Interconnection》 EI CSCD 2024年第1期94-105,共12页
The power Internet of Things(IoT)is a significant trend in technology and a requirement for national strategic development.With the deepening digital transformation of the power grid,China’s power system has initiall... The power Internet of Things(IoT)is a significant trend in technology and a requirement for national strategic development.With the deepening digital transformation of the power grid,China’s power system has initially built a power IoT architecture comprising a perception,network,and platform application layer.However,owing to the structural complexity of the power system,the construction of the power IoT continues to face problems such as complex access management of massive heterogeneous equipment,diverse IoT protocol access methods,high concurrency of network communications,and weak data security protection.To address these issues,this study optimizes the existing architecture of the power IoT and designs an integrated management framework for the access of multi-source heterogeneous data in the power IoT,comprising cloud,pipe,edge,and terminal parts.It further reviews and analyzes the key technologies involved in the power IoT,such as the unified management of the physical model,high concurrent access,multi-protocol access,multi-source heterogeneous data storage management,and data security control,to provide a more flexible,efficient,secure,and easy-to-use solution for multi-source heterogeneous data access in the power IoT. 展开更多
关键词 Power Internet of Things Object model High concurrency access Zero trust mechanism multi-source heterogeneous data
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Comprehensive integration of single-cell transcriptomic data illuminates the regulatory network architecture of plant cell fate specification
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作者 Shanni Cao Xue Zhao +6 位作者 Zhuojin Li Ranran Yu Yuqi Li Xinkai Zhou Wenhao Yan Dijun Chen Chao He 《Plant Diversity》 SCIE CAS CSCD 2024年第3期372-385,共14页
Plant morphogenesis relies on precise gene expression programs at the proper time and position which is orchestrated by transcription factors(TFs)in intricate regulatory networks in a cell-type specific manner.Here we... Plant morphogenesis relies on precise gene expression programs at the proper time and position which is orchestrated by transcription factors(TFs)in intricate regulatory networks in a cell-type specific manner.Here we introduced a comprehensive single-cell transcriptomic atlas of Arabidopsis seedlings.This atlas is the result of meticulous integration of 63 previously published scRNA-seq datasets,addressing batch effects and conserving biological variance.This integration spans a broad spectrum of tissues,including both below-and above-ground parts.Utilizing a rigorous approach for cell type annotation,we identified 47 distinct cell types or states,largely expanding our current view of plant cell compositions.We systematically constructed cell-type specific gene regulatory networks and uncovered key regulators that act in a coordinated manner to control cell-type specific gene expression.Taken together,our study not only offers extensive plant cell atlas exploration that serves as a valuable resource,but also provides molecular insights into gene-regulatory programs that varies from different cell types. 展开更多
关键词 ARABIDOPSIS Single cell transcriptome Gene regulatory network data integration Plant cell atlas
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Runout prediction of potential landslides based on the multi-source data collaboration analysis on historical cases
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作者 Jun Sun Yu Zhuang Ai-guo Xing 《China Geology》 CAS CSCD 2024年第2期264-276,共13页
Long runout landslides involve a massive amount of energy and can be extremely hazardous owing to their long movement distance,high mobility and strong destructive power.Numerical methods have been widely used to pred... Long runout landslides involve a massive amount of energy and can be extremely hazardous owing to their long movement distance,high mobility and strong destructive power.Numerical methods have been widely used to predict the landslide runout but a fundamental problem remained is how to determine the reliable numerical parameters.This study proposes a framework to predict the runout of potential landslides through multi-source data collaboration and numerical analysis of historical landslide events.Specifically,for the historical landslide cases,the landslide-induced seismic signal,geophysical surveys,and possible in-situ drone/phone videos(multi-source data collaboration)can validate the numerical results in terms of landslide dynamics and deposit features and help calibrate the numerical(rheological)parameters.Subsequently,the calibrated numerical parameters can be used to numerically predict the runout of potential landslides in the region with a similar geological setting to the recorded events.Application of the runout prediction approach to the 2020 Jiashanying landslide in Guizhou,China gives reasonable results in comparison to the field observations.The numerical parameters are determined from the multi-source data collaboration analysis of a historical case in the region(2019 Shuicheng landslide).The proposed framework for landslide runout prediction can be of great utility for landslide risk assessment and disaster reduction in mountainous regions worldwide. 展开更多
关键词 Landslide runout prediction Drone survey multi-source data collaboration DAN3D numerical modeling Jianshanying landslide Guizhou Province Geological hazards survey engineering
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Multi-Source Data Privacy Protection Method Based on Homomorphic Encryption and Blockchain 被引量:3
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作者 Ze Xu Sanxing Cao 《Computer Modeling in Engineering & Sciences》 SCIE EI 2023年第7期861-881,共21页
Multi-Source data plays an important role in the evolution of media convergence.Its fusion processing enables the further mining of data and utilization of data value and broadens the path for the sharing and dissemin... Multi-Source data plays an important role in the evolution of media convergence.Its fusion processing enables the further mining of data and utilization of data value and broadens the path for the sharing and dissemination of media data.However,it also faces serious problems in terms of protecting user and data privacy.Many privacy protectionmethods have been proposed to solve the problemof privacy leakage during the process of data sharing,but they suffer fromtwo flaws:1)the lack of algorithmic frameworks for specific scenarios such as dynamic datasets in the media domain;2)the inability to solve the problem of the high computational complexity of ciphertext in multi-source data privacy protection,resulting in long encryption and decryption times.In this paper,we propose a multi-source data privacy protection method based on homomorphic encryption and blockchain technology,which solves the privacy protection problem ofmulti-source heterogeneous data in the dissemination ofmedia and reduces ciphertext processing time.We deployed the proposedmethod on theHyperledger platformfor testing and compared it with the privacy protection schemes based on k-anonymity and differential privacy.The experimental results showthat the key generation,encryption,and decryption times of the proposedmethod are lower than those in data privacy protection methods based on k-anonymity technology and differential privacy technology.This significantly reduces the processing time ofmulti-source data,which gives it potential for use in many applications. 展开更多
关键词 Homomorphic encryption blockchain technology multi-source data data privacy protection privacy data processing
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Recent trends of machine learning applied to multi-source data of medicinal plants 被引量:2
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作者 Yanying Zhang Yuanzhong Wang 《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2023年第12期1388-1407,共20页
In traditional medicine and ethnomedicine,medicinal plants have long been recognized as the basis for materials in therapeutic applications worldwide.In particular,the remarkable curative effect of traditional Chinese... In traditional medicine and ethnomedicine,medicinal plants have long been recognized as the basis for materials in therapeutic applications worldwide.In particular,the remarkable curative effect of traditional Chinese medicine during corona virus disease 2019(COVID-19)pandemic has attracted extensive attention globally.Medicinal plants have,therefore,become increasingly popular among the public.However,with increasing demand for and profit with medicinal plants,commercial fraudulent events such as adulteration or counterfeits sometimes occur,which poses a serious threat to the clinical outcomes and interests of consumers.With rapid advances in artificial intelligence,machine learning can be used to mine information on various medicinal plants to establish an ideal resource database.We herein present a review that mainly introduces common machine learning algorithms and discusses their application in multi-source data analysis of medicinal plants.The combination of machine learning algorithms and multi-source data analysis facilitates a comprehensive analysis and aids in the effective evaluation of the quality of medicinal plants.The findings of this review provide new possibilities for promoting the development and utilization of medicinal plants. 展开更多
关键词 Machine learning Medicinal plant multi-source data data fusion Application
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Multi-source Data-driven Identification of Urban Functional Areas:A Case of Shenyang,China 被引量:3
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作者 XUE Bing XIAO Xiao +2 位作者 LI Jingzhong ZHAO Bingyu FU Bo 《Chinese Geographical Science》 SCIE CSCD 2023年第1期21-35,共15页
Urban functional area(UFA)is a core scientific issue affecting urban sustainability.The current knowledge gap is mainly reflected in the lack of multi-scale quantitative interpretation methods from the perspective of ... Urban functional area(UFA)is a core scientific issue affecting urban sustainability.The current knowledge gap is mainly reflected in the lack of multi-scale quantitative interpretation methods from the perspective of human-land interaction.In this paper,based on multi-source big data include 250 m×250 m resolution cell phone data,1.81×105 Points of Interest(POI)data and administrative boundary data,we built a UFA identification method and demonstrated empirically in Shenyang City,China.We argue that the method we built can effectively identify multi-scale multi-type UFAs based on human activity and further reveal the spatial correlation between urban facilities and human activity.The empirical study suggests that the employment functional zones in Shenyang City are more concentrated in central cities than other single functional zones.There are more mix functional areas in the central city areas,while the planned industrial new cities need to develop comprehensive functions in Shenyang.UFAs have scale effects and human-land interaction patterns.We suggest that city decision makers should apply multi-sources big data to measure urban functional service in a more refined manner from a supply-demand perspective. 展开更多
关键词 human-land relationship multi-source big data urban functional area identification method Shenyang City
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Preserving Data Secrecy and Integrity for Cloud Storage Using Smart Contracts and Cryptographic Primitives
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作者 Maher Alharby 《Computers, Materials & Continua》 SCIE EI 2024年第5期2449-2463,共15页
Cloud computing has emerged as a viable alternative to traditional computing infrastructures,offering various benefits.However,the adoption of cloud storage poses significant risks to data secrecy and integrity.This a... Cloud computing has emerged as a viable alternative to traditional computing infrastructures,offering various benefits.However,the adoption of cloud storage poses significant risks to data secrecy and integrity.This article presents an effective mechanism to preserve the secrecy and integrity of data stored on the public cloud by leveraging blockchain technology,smart contracts,and cryptographic primitives.The proposed approach utilizes a Solidity-based smart contract as an auditor for maintaining and verifying the integrity of outsourced data.To preserve data secrecy,symmetric encryption systems are employed to encrypt user data before outsourcing it.An extensive performance analysis is conducted to illustrate the efficiency of the proposed mechanism.Additionally,a rigorous assessment is conducted to ensure that the developed smart contract is free from vulnerabilities and to measure its associated running costs.The security analysis of the proposed system confirms that our approach can securely maintain the confidentiality and integrity of cloud storage,even in the presence of malicious entities.The proposed mechanism contributes to enhancing data security in cloud computing environments and can be used as a foundation for developing more secure cloud storage systems. 展开更多
关键词 Cloud storage data secrecy data integrity smart contracts CRYPTOGRAPHY
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Sec-Auditor:A Blockchain-Based Data Auditing Solution for Ensuring Integrity and Semantic Correctness
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作者 Guodong Han Hecheng Li 《Computers, Materials & Continua》 SCIE EI 2024年第8期2121-2137,共17页
Currently,there is a growing trend among users to store their data in the cloud.However,the cloud is vulnerable to persistent data corruption risks arising from equipment failures and hacker attacks.Additionally,when ... Currently,there is a growing trend among users to store their data in the cloud.However,the cloud is vulnerable to persistent data corruption risks arising from equipment failures and hacker attacks.Additionally,when users perform file operations,the semantic integrity of the data can be compromised.Ensuring both data integrity and semantic correctness has become a critical issue that requires attention.We introduce a pioneering solution called Sec-Auditor,the first of its kind with the ability to verify data integrity and semantic correctness simultaneously,while maintaining a constant communication cost independent of the audited data volume.Sec-Auditor also supports public auditing,enabling anyone with access to public information to conduct data audits.This feature makes Sec-Auditor highly adaptable to open data environments,such as the cloud.In Sec-Auditor,users are assigned specific rules that are utilized to verify the accuracy of data semantic.Furthermore,users are given the flexibility to update their own rules as needed.We conduct in-depth analyses of the correctness and security of Sec-Auditor.We also compare several important security attributes with existing schemes,demonstrating the superior properties of Sec-Auditor.Evaluation results demonstrate that even for time-consuming file upload operations,our solution is more efficient than the comparison one. 展开更多
关键词 Provable data possession public auditing cloud storage data integrity semantic correctness
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Wearable Healthcare and Continuous Vital Sign Monitoring with IoT Integration
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作者 Hamed Taherdoost 《Computers, Materials & Continua》 SCIE EI 2024年第10期79-104,共26页
Technical and accessibility issues in hospitals often prevent patients from receiving optimal mental and physical health care,which is essential for independent living,especially as societies age and chronic diseases ... Technical and accessibility issues in hospitals often prevent patients from receiving optimal mental and physical health care,which is essential for independent living,especially as societies age and chronic diseases like diabetes and cardiovascular disease become more common.Recent advances in the Internet of Things(IoT)-enabled wearable devices offer potential solutions for remote health monitoring and everyday activity recognition,gaining significant attention in personalized healthcare.This paper comprehensively reviews wearable healthcare technology integrated with the IoT for continuous vital sign monitoring.Relevant papers were extracted and analyzed using a systematic numerical review method,covering various aspects such as sports monitoring,disease detection,patient monitoring,and medical diagnosis.The review highlights the transformative impact of IoTenabled wearable devices in healthcare,facilitating real-time monitoring of vital signs,including blood pressure,temperature,oxygen levels,and heart rate.Results from the reviewed papers demonstrate high accuracy and efficiency in predicting health conditions,improving sports performance,enhancing patient care,and diagnosing diseases.The integration of IoT in wearable healthcare devices enables remote patient monitoring,personalized care,and efficient data transmission,ultimately transcending traditional boundaries of healthcare and leading to better patient outcomes. 展开更多
关键词 Wearable healthcare IoT integration patient care remote patient monitoring real-time data transmission health technology
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Performance Analysis and Optimization of Energy Harvesting Modulation for Multi-User Integrated Data and Energy Transfer
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作者 Yizhe Zhao Yanliang Wu +1 位作者 Jie Hu Kun Yang 《China Communications》 SCIE CSCD 2024年第1期148-162,共15页
Integrated data and energy transfer(IDET)enables the electromagnetic waves to transmit wireless energy at the same time of data delivery for lowpower devices.In this paper,an energy harvesting modulation(EHM)assisted ... Integrated data and energy transfer(IDET)enables the electromagnetic waves to transmit wireless energy at the same time of data delivery for lowpower devices.In this paper,an energy harvesting modulation(EHM)assisted multi-user IDET system is studied,where all the received signals at the users are exploited for energy harvesting without the degradation of wireless data transfer(WDT)performance.The joint IDET performance is then analysed theoretically by conceiving a practical time-dependent wireless channel.With the aid of the AO based algorithm,the average effective data rate among users are maximized by ensuring the BER and the wireless energy transfer(WET)performance.Simulation results validate and evaluate the IDET performance of the EHM assisted system,which also demonstrates that the optimal number of user clusters and IDET time slots should be allocated,in order to improve the WET and WDT performance. 展开更多
关键词 energy harvesting modulation(EHM) integrated data and energy transfer(IDET) performance analysis wireless data transfer(WDT) wireless energy transfer(WET)
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Enhancing Data Analysis and Automation: Integrating Python with Microsoft Excel for Non-Programmers
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作者 Osama Magdy Ali Mohamed Breik +2 位作者 Tarek Aly Atef Tayh Nour El-Din Raslan Mervat Gheith 《Journal of Software Engineering and Applications》 2024年第6期530-540,共11页
Microsoft Excel is essential for the End-User Approach (EUA), offering versatility in data organization, analysis, and visualization, as well as widespread accessibility. It fosters collaboration and informed decision... Microsoft Excel is essential for the End-User Approach (EUA), offering versatility in data organization, analysis, and visualization, as well as widespread accessibility. It fosters collaboration and informed decision-making across diverse domains. Conversely, Python is indispensable for professional programming due to its versatility, readability, extensive libraries, and robust community support. It enables efficient development, advanced data analysis, data mining, and automation, catering to diverse industries and applications. However, one primary issue when using Microsoft Excel with Python libraries is compatibility and interoperability. While Excel is a widely used tool for data storage and analysis, it may not seamlessly integrate with Python libraries, leading to challenges in reading and writing data, especially in complex or large datasets. Additionally, manipulating Excel files with Python may not always preserve formatting or formulas accurately, potentially affecting data integrity. Moreover, dependency on Excel’s graphical user interface (GUI) for automation can limit scalability and reproducibility compared to Python’s scripting capabilities. This paper covers the integration solution of empowering non-programmers to leverage Python’s capabilities within the familiar Excel environment. This enables users to perform advanced data analysis and automation tasks without requiring extensive programming knowledge. Based on Soliciting feedback from non-programmers who have tested the integration solution, the case study shows how the solution evaluates the ease of implementation, performance, and compatibility of Python with Excel versions. 展开更多
关键词 PYTHON End-User Approach Microsoft Excel data Analysis integration SPREADSHEET PROGRAMMING data Visualization
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Analysis of Traffic Accidents Based on the Integration Model
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作者 Yanshun Ma Yi Shi +2 位作者 Yihang Song Chenxiao Wu Yuanzhi Liu 《Journal of Electronic Research and Application》 2024年第1期51-59,共9页
To enhance the safety of road traffic operations,this paper proposed a model based on stacking integrated learning utilizing American road traffic accident statistics.Initially,the process involved data cleaning,trans... To enhance the safety of road traffic operations,this paper proposed a model based on stacking integrated learning utilizing American road traffic accident statistics.Initially,the process involved data cleaning,transformation,and normalization.Subsequently,various classification models were constructed,including logistic regression,k-nearest neighbors,gradient boosting,decision trees,AdaBoost,and extra trees models.Evaluation metrics such as accuracy,precision,recall,F1 score,and Hamming loss were employed.Upon analysis,the passive-aggressive classifier model exhibited superior comprehensive indices compared to other models.Based on the model’s output results,an in-depth examination of the factors influencing traffic accidents was conducted.Additionally,measures and suggestions aimed at reducing the incidence of severe traffic accidents were presented.These findings served as a valuable reference for mitigating the occurrence of traffic accidents. 展开更多
关键词 Stacking integrated learning data analysis Traffic safety
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Risk Analysis Using Multi-Source Data for Distribution Networks Facing Extreme Natural Disasters
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作者 Jun Yang Nannan Wang +1 位作者 Jiang Wang Yashuai Luo 《Energy Engineering》 EI 2023年第9期2079-2096,共18页
Distribution networks denote important public infrastructure necessary for people’s livelihoods.However,extreme natural disasters,such as earthquakes,typhoons,and mudslides,severely threaten the safe and stable opera... Distribution networks denote important public infrastructure necessary for people’s livelihoods.However,extreme natural disasters,such as earthquakes,typhoons,and mudslides,severely threaten the safe and stable operation of distribution networks and power supplies needed for daily life.Therefore,considering the requirements for distribution network disaster prevention and mitigation,there is an urgent need for in-depth research on risk assessment methods of distribution networks under extreme natural disaster conditions.This paper accessesmultisource data,presents the data quality improvement methods of distribution networks,and conducts data-driven active fault diagnosis and disaster damage analysis and evaluation using data-driven theory.Furthermore,the paper realizes real-time,accurate access to distribution network disaster information.The proposed approach performs an accurate and rapid assessment of cross-sectional risk through case study.The minimal average annual outage time can be reduced to 3 h/a in the ring network through case study.The approach proposed in this paper can provide technical support to the further improvement of the ability of distribution networks to cope with extreme natural disasters. 展开更多
关键词 Distribution network disaster damage analysis fault judgment multi-source data
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Evaluation and Improvement Strategies for Slow Traffic Systems Based on Multi-source Big Data:A Case Study of Shijingshan District of Beijing City
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作者 LI Yiwen 《Journal of Landscape Research》 2023年第4期62-64,68,共4页
The slow traffic system is an important component of urban transportation,and the prerequisite and necessary condition for Beijing to continue promoting“green priority”are establishing a good urban slow traffic syst... The slow traffic system is an important component of urban transportation,and the prerequisite and necessary condition for Beijing to continue promoting“green priority”are establishing a good urban slow traffic system.Shijingshan District of Beijing City is taken as a research object.By analyzing and processing population distribution data,POI data,and shared bicycle data,the shortcomings and deficiencies of the current slow traffic system in Shijingshan District are explored,and corresponding solutions are proposed,in order to provide new ideas and methods for future urban planning from the perspective of data. 展开更多
关键词 multi-source data Slow traffic system Shijingshan District
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Classification of Beijing Line 10 Subway Living Circle Based on Multi-source Big Data
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作者 SUN Shuai LI Ziying 《Journal of Landscape Research》 2023年第3期53-58,共6页
In the first-tier cities,subway has become an important carrier and life focus of people’s daily travel activities.By studying the distribution of POIs of public service facilities around Metro Line 10,using GIS to q... In the first-tier cities,subway has become an important carrier and life focus of people’s daily travel activities.By studying the distribution of POIs of public service facilities around Metro Line 10,using GIS to quantitatively analyze the surrounding formats of subway stations,discussing the functional attributes of subway stations,and discussing the distribution of urban functions from a new perspective,this paper provided guidance and advice for the construction of service facilities. 展开更多
关键词 multi-source big data Subway living circle BEIJING GIS
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Integrating Multi-Source Web Records into Relational Database 被引量:1
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作者 HUANG Jianbin JI Hongbing SUN Heli 《Wuhan University Journal of Natural Sciences》 CAS 2006年第5期1177-1181,共5页
How to integrate heterogeneous semi-structured Web records into relational database is an important and challengeable research topic. An improved model of conditional random fields was presented to combine the learnin... How to integrate heterogeneous semi-structured Web records into relational database is an important and challengeable research topic. An improved model of conditional random fields was presented to combine the learning of labeled samples and unlabeled database records in order to reduce the dependence on tediously hand-labeled training data. The pro- posed model was used to solve the problem of schema matching between data source schema and database schema. Experimental results using a large number of Web pages from diverse domains show the novel approach's effectiveness. 展开更多
关键词 Web data integration schema matching conditional random fields
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Semantic-based query processing for relational data integration 被引量:1
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作者 苗壮 张亚非 +2 位作者 王进鹏 陆建江 周波 《Journal of Southeast University(English Edition)》 EI CAS 2011年第1期22-25,共4页
To solve the query processing correctness problem for semantic-based relational data integration,the semantics of SAPRQL(simple protocol and RDF query language) queries is defined.In the course of query rewriting,al... To solve the query processing correctness problem for semantic-based relational data integration,the semantics of SAPRQL(simple protocol and RDF query language) queries is defined.In the course of query rewriting,all relative tables are found and decomposed into minimal connectable units.Minimal connectable units are joined according to semantic queries to produce the semantically correct query plans.Algorithms for query rewriting and transforming are presented.Computational complexity of the algorithms is discussed.Under the worst case,the query decomposing algorithm can be finished in O(n2) time and the query rewriting algorithm requires O(nm) time.And the performance of the algorithms is verified by experiments,and experimental results show that when the length of query is less than 8,the query processing algorithms can provide satisfactory performance. 展开更多
关键词 data integration relational database simple protocol and RDF query language(SPARQL) minimal connectable unit query processing
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Separation method for multi-source blended seismic data
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作者 王汉闯 陈生昌 +1 位作者 张博 佘德平 《Applied Geophysics》 SCIE CSCD 2013年第3期251-264,357,共15页
Multi-source seismic technology is an efficient seismic acquisition method that requires a group of blended seismic data to be separated into single-source seismic data for subsequent processing. The separation of ble... Multi-source seismic technology is an efficient seismic acquisition method that requires a group of blended seismic data to be separated into single-source seismic data for subsequent processing. The separation of blended seismic data is a linear inverse problem. According to the relationship between the shooting number and the simultaneous source number of the acquisition system, this separation of blended seismic data is divided into an easily determined or overdetermined linear inverse problem and an underdetermined linear inverse problem that is difficult to solve. For the latter, this paper presents an optimization method that imposes the sparsity constraint on wavefields to construct the object function of inversion, and the problem is solved by using the iterative thresholding method. For the most extremely underdetermined separation problem with single-shooting and multiple sources, this paper presents a method of pseudo-deblending with random noise filtering. In this method, approximate common shot gathers are received through the pseudo-deblending process, and the random noises that appear when the approximate common shot gathers are sorted into common receiver gathers are eliminated through filtering methods. The separation methods proposed in this paper are applied to three types of numerical simulation data, including pure data without noise, data with random noise, and data with linear regular noise to obtain satisfactory results. The noise suppression effects of these methods are sufficient, particularly with single-shooting blended seismic data, which verifies the effectiveness of the proposed methods. 展开更多
关键词 multi-source data separation linear inverse problem sparsest constraint pseudo-deblending filtering
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Integrative multi-omics and systems bioinformatics in translational neuroscience:A data mining perspective 被引量:4
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作者 Lance M.O'Connor Blake A.O'Connor +2 位作者 Su Bin Lim Jialiu Zeng Chih Hung Lo 《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2023年第8期836-850,共15页
Bioinformatic analysis of large and complex omics datasets has become increasingly useful in modern day biology by providing a great depth of information,with its application to neuroscience termed neuroinformatics.Da... Bioinformatic analysis of large and complex omics datasets has become increasingly useful in modern day biology by providing a great depth of information,with its application to neuroscience termed neuroinformatics.Data mining of omics datasets has enabled the generation of new hypotheses based on differentially regulated biological molecules associated with disease mechanisms,which can be tested experimentally for improved diagnostic and therapeutic targeting of neurodegenerative diseases.Importantly,integrating multi-omics data using a systems bioinformatics approach will advance the understanding of the layered and interactive network of biological regulation that exchanges systemic knowledge to facilitate the development of a comprehensive human brain profile.In this review,we first summarize data mining studies utilizing datasets from the individual type of omics analysis,including epigenetics/epigenomics,transcriptomics,proteomics,metabolomics,lipidomics,and spatial omics,pertaining to Alzheimer's disease,Parkinson's disease,and multiple sclerosis.We then discuss multi-omics integration approaches,including independent biological integration and unsupervised integration methods,for more intuitive and informative interpretation of the biological data obtained across different omics layers.We further assess studies that integrate multi-omics in data mining which provide convoluted biological insights and offer proof-of-concept proposition towards systems bioinformatics in the reconstruction of brain networks.Finally,we recommend a combination of high dimensional bioinformatics analysis with experimental validation to achieve translational neuroscience applications including biomarker discovery,therapeutic development,and elucidation of disease mechanisms.We conclude by providing future perspectives and opportunities in applying integrative multi-omics and systems bioinformatics to achieve precision phenotyping of neurodegenerative diseases and towards personalized medicine. 展开更多
关键词 Multi-omics integration Systems bioinformatics data mining Human brain profile reconstruction Translational neuroscience
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