TiO2 is a wide band gap semiconductor with important applications in photovoltaic cells. Vertically aligned Tit2 nanorod arrays （NRs） are grown on the fluorine-doped tin oxide （FTO） substrates by a multicycle hydr...TiO2 is a wide band gap semiconductor with important applications in photovoltaic cells. Vertically aligned Tit2 nanorod arrays （NRs） are grown on the fluorine-doped tin oxide （FTO） substrates by a multicycle hydrothermal synthesis process. The samples are characterized by X-ray diffraction （XRD）, scanning electron microscopy （SEM）, high-resolution transmission electron microscopy （HRTEM）, and selected-area electron diffraction （SAED）. It is found that dye-sensitized solar cells （DSSCs） assembled by the as-prepared Tit2 single-crystal NRs exhibit different trends under the condition of different nucleation and growth concentrations. Optimum cell performance is obtained with high nucleation concentration and low growth cycle concentration. The efficiency enhancement is mainly attributed to the improved specific surface area of the nanorod.展开更多
Four kinds of Ca-based sorbents were prepared by calcination and hydration reactions using different precursors： calcium hydroxide, calcium carbonate, calcium acetate monohydrate and calcium oxide. The CO2 absorption...Four kinds of Ca-based sorbents were prepared by calcination and hydration reactions using different precursors： calcium hydroxide, calcium carbonate, calcium acetate monohydrate and calcium oxide. The CO2 absorption capacity of those sorbents was investigated in a fixed-bed reactor in the temperature range of 350-650 ℃. It was found that all of those sorbents showed higher capacity for CO2 absorption when the operating temperature higher than 450 ℃. The CaAc2-CaO sorbent showed the highest CO2 absorption capacity of 299 mg.g-1. The mor- phology of those sorbents was examined by scanning electron microscope （SEM）, and the changes of composition before and after carbonation were also determined by X-ray diffraction （XRD）. Results indicated that those sorbents have the similar chemical compositions and crystalline phases before carbonation reaction [mainly Ca（OH）2], and CaCO3 is the main component after carbonation reaction. The SEM morphology shows clearly that the sorbent pores were filled with reaction products after carbonation reaction, and became much denser than before. The N2 adsorption-desorption isotherms indicated that the CaAc2-CaO and CaCO3-CaO sorbents have higher specific surface area. lar2er oore volume and anoropriate pore size distribution than that of CaO-CaO and Ca（OH）2-CaO.展开更多
By conducting relative permeability experiments of multi-cycle gas-water displacement and imbibition on natural cores,we discuss relative permeability hysteresis effect in underground gas storage during multi-cycle in...By conducting relative permeability experiments of multi-cycle gas-water displacement and imbibition on natural cores,we discuss relative permeability hysteresis effect in underground gas storage during multi-cycle injection and production.A correction method for relative permeability hysteresis in numerical simulation of water-invaded gas storage has been worked out using the Carlson and Killough models.A geologic model of water-invaded sandstone gas storage with medium-low permeability is built to investigate the impacts of relative permeability hysteresis on fluid distribution and production performance during multi-cycle injection and production of the gas storage.The study shows that relative permeability hysteresis effect occurs during high-speed injection and production in gas storage converted from water-invaded gas reservoir,and leads to increase of gas-water transition zone width and thickness,shrinkage of the area of high-efficiency gas storage,and decrease of the peak value variation of pore volume containing gas,and then reduces the storage capacity,working gas volume,and high-efficiency operation span of the gas storage.Numerical simulations exhibit large prediction errors of performance indexes if this hysteresis effect is not considered.Killough and Carlson methods can be used to correct the relative permeability hysteresis effect in water-invaded underground gas storage to improve the prediction accuracy.The Killough method has better adaptability to the example model.展开更多
Different novel fused multicyclic iminosugars were synthesized from D-ribose tosylate,aniline and vinyl ethyl ether by one-pot three-component stereoselective[4+2]reaction at different temperatures.The iminium-ion is ...Different novel fused multicyclic iminosugars were synthesized from D-ribose tosylate,aniline and vinyl ethyl ether by one-pot three-component stereoselective[4+2]reaction at different temperatures.The iminium-ion is the key intermediate for the reaction.As a result,several complex fused iminosugars 3a were obtained by aza-Diels-Alder mechanism at 60℃,while a series of aza-C-glycosides 5a were prepared by Mannich reaction at room temperature accompanied by another tetrahydroquinoline-fused iminosugars 4a(tricyclic derivatives)through aza-Diels-Alder cycloaddition.This strategy will help to construct structurally diverse and bioactive iminosugar analogues.展开更多
Affinity reagents are important tools in the biological sciences for understanding biological processes and for studying protein expression, localization and interactions. However, traditional affinity reagents such a...Affinity reagents are important tools in the biological sciences for understanding biological processes and for studying protein expression, localization and interactions. However, traditional affinity reagents such as antibodies(and their fragments) and non-immunoglobulin(non-Ig) scaffold binders, usually suffer from problems of poor cellular uptake efficiency, high production cost, and low structural stability. This leads to rapid development of small antibody-like affinity reagents such as scaffold-free cyclic and multicyclic peptides, which usually have 5-30 amino acid residues, thus lying between non-Ig scaffolds and small molecules in size. In this mini-review, we highlight the recent development in mono-and multi-cyclic peptide mimics of antibodies, including cyclic peptide affinity reagents that have been developed for use in antibody-like applications, novel synthetic strategies for multicyclic peptides, and promising peptide library screening platforms. We also provide a perspective on the future development in multicyclic peptide mimics of antibodies.展开更多
基金Project supported by the Fundamental Research Funds for the Central Universities,China(Grant No.2013XK07)
文摘TiO2 is a wide band gap semiconductor with important applications in photovoltaic cells. Vertically aligned Tit2 nanorod arrays （NRs） are grown on the fluorine-doped tin oxide （FTO） substrates by a multicycle hydrothermal synthesis process. The samples are characterized by X-ray diffraction （XRD）, scanning electron microscopy （SEM）, high-resolution transmission electron microscopy （HRTEM）, and selected-area electron diffraction （SAED）. It is found that dye-sensitized solar cells （DSSCs） assembled by the as-prepared Tit2 single-crystal NRs exhibit different trends under the condition of different nucleation and growth concentrations. Optimum cell performance is obtained with high nucleation concentration and low growth cycle concentration. The efficiency enhancement is mainly attributed to the improved specific surface area of the nanorod.
基金Supported by the National Natural Science Foundation of China （21006053）, the Fundamental Research Funds for the Central Universities （65010551） and Special Projects of Environmental Protection （2009ZX07208）.
文摘Four kinds of Ca-based sorbents were prepared by calcination and hydration reactions using different precursors： calcium hydroxide, calcium carbonate, calcium acetate monohydrate and calcium oxide. The CO2 absorption capacity of those sorbents was investigated in a fixed-bed reactor in the temperature range of 350-650 ℃. It was found that all of those sorbents showed higher capacity for CO2 absorption when the operating temperature higher than 450 ℃. The CaAc2-CaO sorbent showed the highest CO2 absorption capacity of 299 mg.g-1. The mor- phology of those sorbents was examined by scanning electron microscope （SEM）, and the changes of composition before and after carbonation were also determined by X-ray diffraction （XRD）. Results indicated that those sorbents have the similar chemical compositions and crystalline phases before carbonation reaction [mainly Ca（OH）2], and CaCO3 is the main component after carbonation reaction. The SEM morphology shows clearly that the sorbent pores were filled with reaction products after carbonation reaction, and became much denser than before. The N2 adsorption-desorption isotherms indicated that the CaAc2-CaO and CaCO3-CaO sorbents have higher specific surface area. lar2er oore volume and anoropriate pore size distribution than that of CaO-CaO and Ca（OH）2-CaO.
基金Supported by the Petro China Science and Technology Major Project(2015E-4002)。
文摘By conducting relative permeability experiments of multi-cycle gas-water displacement and imbibition on natural cores,we discuss relative permeability hysteresis effect in underground gas storage during multi-cycle injection and production.A correction method for relative permeability hysteresis in numerical simulation of water-invaded gas storage has been worked out using the Carlson and Killough models.A geologic model of water-invaded sandstone gas storage with medium-low permeability is built to investigate the impacts of relative permeability hysteresis on fluid distribution and production performance during multi-cycle injection and production of the gas storage.The study shows that relative permeability hysteresis effect occurs during high-speed injection and production in gas storage converted from water-invaded gas reservoir,and leads to increase of gas-water transition zone width and thickness,shrinkage of the area of high-efficiency gas storage,and decrease of the peak value variation of pore volume containing gas,and then reduces the storage capacity,working gas volume,and high-efficiency operation span of the gas storage.Numerical simulations exhibit large prediction errors of performance indexes if this hysteresis effect is not considered.Killough and Carlson methods can be used to correct the relative permeability hysteresis effect in water-invaded underground gas storage to improve the prediction accuracy.The Killough method has better adaptability to the example model.
基金supported by the National Natural Science Foundation of China(NSFC)(21772031)the Natural Science Foundations of Hebei Province(B2019201398).
文摘Different novel fused multicyclic iminosugars were synthesized from D-ribose tosylate,aniline and vinyl ethyl ether by one-pot three-component stereoselective[4+2]reaction at different temperatures.The iminium-ion is the key intermediate for the reaction.As a result,several complex fused iminosugars 3a were obtained by aza-Diels-Alder mechanism at 60℃,while a series of aza-C-glycosides 5a were prepared by Mannich reaction at room temperature accompanied by another tetrahydroquinoline-fused iminosugars 4a(tricyclic derivatives)through aza-Diels-Alder cycloaddition.This strategy will help to construct structurally diverse and bioactive iminosugar analogues.
基金the financial support from the National Natural Science Foundation of China(No.21475109)the Program for Changjiang Scholars and Innovative Research Team in University(No. IRT13036)the Foundation for Innovative Research Groups of the National Natural Science Foundation of China(No. 21521004)
文摘Affinity reagents are important tools in the biological sciences for understanding biological processes and for studying protein expression, localization and interactions. However, traditional affinity reagents such as antibodies(and their fragments) and non-immunoglobulin(non-Ig) scaffold binders, usually suffer from problems of poor cellular uptake efficiency, high production cost, and low structural stability. This leads to rapid development of small antibody-like affinity reagents such as scaffold-free cyclic and multicyclic peptides, which usually have 5-30 amino acid residues, thus lying between non-Ig scaffolds and small molecules in size. In this mini-review, we highlight the recent development in mono-and multi-cyclic peptide mimics of antibodies, including cyclic peptide affinity reagents that have been developed for use in antibody-like applications, novel synthetic strategies for multicyclic peptides, and promising peptide library screening platforms. We also provide a perspective on the future development in multicyclic peptide mimics of antibodies.
