patients with multiple myeloma (MM) were investigated for lymphocyte subsets using APAAP (Alkaline Phosphastase Anti-Alkaline Phosphatase) technique and a panel of monoclonal antibodies.Radioimmunoassay was used to ex...patients with multiple myeloma (MM) were investigated for lymphocyte subsets using APAAP (Alkaline Phosphastase Anti-Alkaline Phosphatase) technique and a panel of monoclonal antibodies.Radioimmunoassay was used to examine serum beta-2-microglobulin (Sβ2-MG).The results showed that OKT3, OKT4 positive cells and OKT4/OKT8 ratio reduced significantly. OKT8 positive cells increased sharply in MM. We conclude that,in MM,all patients have severe abnormalities in the number and proportion of T cells.The level of S β2-MG increased significantly, especially in the initial and relapsing patients.But,we did not find the relationship between Sβ2-MG and T subsets.展开更多
文摘patients with multiple myeloma (MM) were investigated for lymphocyte subsets using APAAP (Alkaline Phosphastase Anti-Alkaline Phosphatase) technique and a panel of monoclonal antibodies.Radioimmunoassay was used to examine serum beta-2-microglobulin (Sβ2-MG).The results showed that OKT3, OKT4 positive cells and OKT4/OKT8 ratio reduced significantly. OKT8 positive cells increased sharply in MM. We conclude that,in MM,all patients have severe abnormalities in the number and proportion of T cells.The level of S β2-MG increased significantly, especially in the initial and relapsing patients.But,we did not find the relationship between Sβ2-MG and T subsets.
