Purpose: To observe and compare the effects of pupil dilation between Mydrin-P and compound tropicamide in the screening of retinopathy of prematurity.Methods:.The right eyes of premature infants received Mydrin-P eye...Purpose: To observe and compare the effects of pupil dilation between Mydrin-P and compound tropicamide in the screening of retinopathy of prematurity.Methods:.The right eyes of premature infants received Mydrin-P eye drops as the treatment group, whereas the left eyes were administered with compound tropicamide as the control group..The eye drops were delivered every 5 min for three times..The pupil size was observed and recorded at 10,.15,and 20 min after administering mydriasis.Results:.The mean pupil diameter did not significantly differ between the treatment and control groups at 10.(6.24 ±0.72 mm vs. 6.24±0.68 mm, t=0.00, P=1.00), 15(6.83±0.55 mm vs. 6.78±0.54 mm, t=1.75, P=0.083) or 20 min(7.22±0.40 mm vs. 7.15±0.50 mm, t=1.62, P=0.109), respectively. However, the mean pupil size at any two time points significantly differed in both groups(all P<0.001).Conclusion: Both Mydrin-P and compound tropicamide exert similar clinical efficacy in the screening of retinopathy of prematurity..The most appropriate time for screening was at 20 min after mydriasis.展开更多
基金Special Fund for Science and Technology Development of Foshan(grant No.:2012AA100201)
文摘Purpose: To observe and compare the effects of pupil dilation between Mydrin-P and compound tropicamide in the screening of retinopathy of prematurity.Methods:.The right eyes of premature infants received Mydrin-P eye drops as the treatment group, whereas the left eyes were administered with compound tropicamide as the control group..The eye drops were delivered every 5 min for three times..The pupil size was observed and recorded at 10,.15,and 20 min after administering mydriasis.Results:.The mean pupil diameter did not significantly differ between the treatment and control groups at 10.(6.24 ±0.72 mm vs. 6.24±0.68 mm, t=0.00, P=1.00), 15(6.83±0.55 mm vs. 6.78±0.54 mm, t=1.75, P=0.083) or 20 min(7.22±0.40 mm vs. 7.15±0.50 mm, t=1.62, P=0.109), respectively. However, the mean pupil size at any two time points significantly differed in both groups(all P<0.001).Conclusion: Both Mydrin-P and compound tropicamide exert similar clinical efficacy in the screening of retinopathy of prematurity..The most appropriate time for screening was at 20 min after mydriasis.
