期刊文献+
共找到9篇文章
< 1 >
每页显示 20 50 100
Glycopolymer N-halamine-modified biochars with high specificity for Escherichia coli eradication
1
作者 Qinggele Borjihan Quanfu Yao +3 位作者 Huihui Qu Haixia Wu Ying Liu Alideertu Dong 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2021年第10期229-236,共8页
Antibiotic-resistant bacteria contamination in environments imposes great threats to human life health.This research aims to develop novel targeted antibacterial biochars for achieving high selectivity to kill pathoge... Antibiotic-resistant bacteria contamination in environments imposes great threats to human life health.This research aims to develop novel targeted antibacterial biochars for achieving high selectivity to kill pathogenic Escherichia coli(E.coli).The glycopolymer N-halamine-modified biochars(i.e.,BCPMA-Cl)were synthesized by the modification of biochars with poly[2-(methacrylamido)glucopyranose-coacrylamide](P(MAG-co-AM),followed by chlorination treatment.Based on the results of FTIR,turbidity,XPS,and UV–vis,BCPMA-Cl was successfully synthesized and demonstrated to be able to eliminate Staphylococcus aureus(S.aureus)and E.coli.Especially,BCPMA-Cl possessed extremely potent to specific-killing 10^(4) CFU·ml^(-1) of E.coli with lower hemolytic activity(<5%).Additionally,the antibacterial mechanisms of BCPMA-Cl against bacteria were contact-killing and release-killing contributed by active chlorine(i.e.,Cl^(+)).Therefore,this work provided a cost-effective and facile approach for preparation of functional biochars used for bacteria-specific therapeutic applications via livestock pollutants as well as showing a promising strategy to avoid bacterial resistance. 展开更多
关键词 Biochars n-halamine GLYCOPOLYMER Antibacterial coating Specific killing
下载PDF
Electro-spinning Antimicrobial N-halamine Modified Poly(vinyl alcohol)Nanofibers
2
作者 姜潜远 任学宏 黄东时 《Journal of Donghua University(English Edition)》 EI CAS 2014年第1期44-49,共6页
Antimicrobial poly( vinyl alcohol)( PVA) nanofibrous composites were prepared by adding 3-( 2,3-dihydroxypropyl)-5,5-dimethylimidazolidine-2,4-dione( N-halamine diol) to the PVA solution using electro-spinning techniq... Antimicrobial poly( vinyl alcohol)( PVA) nanofibrous composites were prepared by adding 3-( 2,3-dihydroxypropyl)-5,5-dimethylimidazolidine-2,4-dione( N-halamine diol) to the PVA solution using electro-spinning technique upon curing and exposure to diluted sodium hypochlorite. Scanning electron microscopy( SEM) demonstrates that PVA nanofibers formed with diameters of( 255 ±94) nm. Cross-linked PVA nanofibers with N-halamine diol precursor and 1,2,3,4-butanetetracarboxylic( BTCA) showed good water resistance. The chlorinated PVA nanofibrous mats completely inactivated Staphylococcus aureus( Gram-positive) and Escherichia coli O157: H7( Gram-negative) with 7 log reductions( the reduction of the bacterial concentration in logarithm) within 5min and 1 min of contact time,respectively. 展开更多
关键词 poly(vinyl alcohol)(PVA) ANTIMICROBIAL NANOFIBER electro-spinning n-halamine
下载PDF
Electrospun N-halamine/ZnO-based platform eradicates bacteria through multimodal antimicrobial mechanism of action 被引量:2
3
作者 Hui-Hui Qu Cong Wang +6 位作者 Yi-Xuan Guo Zi-Ying Zhao Long Qiao Jie-Bing Yang Hai-Xia Wu Quan-Shun Li Alideertu Dong 《Rare Metals》 SCIE EI CAS CSCD 2023年第1期222-233,共12页
The emergence and prevalence of antibiotic-resistant bacteria demands powerful antibacterial tactics to combat infectious microorganisms.Enhanced combinational therapy based on synergistic hybrid antibacterial materia... The emergence and prevalence of antibiotic-resistant bacteria demands powerful antibacterial tactics to combat infectious microorganisms.Enhanced combinational therapy based on synergistic hybrid antibacterial materials is a promising approach to realize effective sterilization through the rational integration of distinct bactericides into one compact platform.In this work,we constructed a microfiber-based antibacterial platform(PAM-Cl/ZnO MFs)by electrospinning N-halamine polymers(PAM-Cl)loaded with zinc oxide(ZnO)nanoparticles.The as-designed PAM-Cl/ZnO MFs inherited the intrinsic antibacterial effects of both PAM-Cl microfibers(PAM-Cl MFs)and ZnO microfibers(ZnO MFs),and the material exhibited enhanced synergistic antibacterial performance against Staphylococcus aureus(S.aureus)and Escherichia coli(E.coli)in vitro.The bactericidal effect was multimodal and included contact killing based on the N-Cl bond of N-halamine,multiple-release killing,such as reactive oxygen species(ROS)under light irritation,and Zn^(2+)and Cl^(+)acting as antibacterial agents.Importantly,PAM-Cl/Zno MFs worked on inactivate bacteria even under harsh temperatures and atmospheric conditions.Additionally,PAM-Cl/ZnO MFs exhibited good biocompatibility and performed outstanding acceleration of wound healing with in vivo mouse skin defect models using S.aureus.This work advances the design of antibacterial hybrid materials with the potency to eradicate bacteria in biological systems in multiple settings through the superiority of multimodal synergistic therapy. 展开更多
关键词 n-halamine ZnO nanoparticles ELECTROSPINNING Synergistic antibacterial therapy Various scenarios
原文传递
Synthesis, characterization and antibacterial properties of multifunctional hindered amine light stabilizers 被引量:3
4
作者 Yi Deng Wei Chen +3 位作者 Tao Yu Li Gong Chen Fang Liu Chun Wei Xin 《Chinese Chemical Letters》 SCIE CAS CSCD 2008年第9期1071-1074,共4页
A series of novel hindered amine light stabilizers containing an N-halamine moiety were designed and synthesized. Their structures were characterized by FT-IR, 1H NMR, and MS. The compounds were tested for antibacteri... A series of novel hindered amine light stabilizers containing an N-halamine moiety were designed and synthesized. Their structures were characterized by FT-IR, 1H NMR, and MS. The compounds were tested for antibacterial activity against Candida albicans, Staphylococcus aureus, and Escherichia coll. At a concentration of 0.5 mmol/L, these compounds all exhibited satisfactory antibacterial activity against all the three types of bacteria. 展开更多
关键词 Reactive-HALS Antibacterial property n-halamine SYNTHESIS
下载PDF
Preparation of quaternarized N-halamine-grafted graphene oxide nanocomposites and synergetic antibacterial properties 被引量:2
5
作者 Danlin Bu Yu Zhou +7 位作者 Chang Yang Hengyu Feng Chunxia Cheng Mengjie Zhang Zice Xu Linghan Xiao Yujing Liu Zhenai Jin 《Chinese Chemical Letters》 SCIE CAS CSCD 2021年第11期3509-3513,共5页
At present,frequent outbreaks of bacteria and viruses have seriously affected people's normal lives.Therefore,the study of broad-spectrum antibacterial nanocomposites is very promising.However,most antibacterial m... At present,frequent outbreaks of bacteria and viruses have seriously affected people's normal lives.Therefore,the study of broad-spectrum antibacterial nanocomposites is very promising.However,most antibacterial materials have some disadvantages,such as single bactericidal mechanisms and unrepeatable use.Based on the current situation,a kind of nanocomposite with three structures of graphene oxide(GO),quaternary ammonium salt(QAs)and N-halamine was prepared,which showed synergistic effect to improve antibacterial activity and combined with a variety of sterilization mechanisms.Meanwhile,GO can provide richer ways of sterilization and high specific surface area,which is conducive to the grafting of quaternarized N-halamine.The advantages of physical sterilization of GO,charge adsorption of QAs,reuse of N-halamine and efficient sterilization are fully utilized.The results showed that the quaternarized N-halamine-grafted GO was obtained successfully.GO grafted with quaternarized N-halamine polymer showed strong speedy bactericidal activity against Escherichia coli(E.coli)and Staphylococcus aureus(S.aureus)(99%).It had good storage and regeneration properties. 展开更多
关键词 n-halamine Quaternary ammonia salt Graphene oxide Synergetic sterilization Nanocomposite
原文传递
新合成橡胶可触杀细菌
6
《国际医药卫生导报》 2000年第7期31-31,共1页
Aubum大学的Sehelby Davis Worley博士报告,他们的实验证明,向含有聚苯乙烯的橡胶中加入氯和与有氯结合的N-halamines,这种经过改造的橡胶可在30分钟内杀死高浓度的病原菌。经过一段时间橡胶中的氯气耗尽,仅将其浸入家用浓度的氯漂... Aubum大学的Sehelby Davis Worley博士报告,他们的实验证明,向含有聚苯乙烯的橡胶中加入氯和与有氯结合的N-halamines,这种经过改造的橡胶可在30分钟内杀死高浓度的病原菌。经过一段时间橡胶中的氯气耗尽,仅将其浸入家用浓度的氯漂白剂中就可恢复。母亲每个月可以将橡胶奶头浸入氯漂白剂一次, 展开更多
关键词 合成橡胶 杀细菌作用 聚苯乙烯 n-halamines 病原菌 抗微生物特性
全文增补中
Promotion of reactive oxygen species activated by nanosilver surface engineering for resistant bacteria-infected skin tissue therapy
7
作者 Pei-Pei Li Yu Zhang +7 位作者 Chao Wang Shu-Jie Wang Wen-Qing Yan Dou-Xin Xiao Jing Kang De-Zhi Yang Hai-Xia Wu Alideertu Dong 《Rare Metals》 SCIE EI CAS CSCD 2023年第12期4167-4183,共17页
Nanosilver has been regarded as a promising alternative to traditional antibiotics for fighting pathogenassociated infections due to its efficacy toward a broad spectrum of pathogens.However,bacterial resistance to na... Nanosilver has been regarded as a promising alternative to traditional antibiotics for fighting pathogenassociated infections due to its efficacy toward a broad spectrum of pathogens.However,bacterial resistance to nanosilver has emerged recently.In this contribution,a surface engineering strategy based on N-halamine chemistry to address bacterial resistance to nanosilver was proposed.Using 1,3-dichloro-5,5-dimethylhydantoin(DCDMH)as an N-halamine source,AgCI nanodots were deposited on the surface of Ag nano wires(Ag NWs)via in situ redox reaction to prepare AgCl-on-Ag NWs.After in vitro and in vivo tests,AgCl-on-Ag NWs effectively inactivated two antibiotic-resistant bacteria,ampicillinresistant Escherichia coli(AREC)and methicillin-resistant Staphylococcus aureus(MRSA)with the minimum bactericidal concentration(MBC)as low as 10μg·ml~(-1)and exhibited good biosafety against normal cells.The experimental and theoretical tests demonstrated that AgCl-onAg NWs worked on AREC and MAS A by generating high level of reactive oxygen species under visible light irradiation,coupled with the sustained Ag ion release.Meanwhile,the antibacterial mechanism of AgCl-on-Ag NWs against MRSA was verified at the gene level by transcriptome analysis(RNA sequencing).Moreover,the fullthickness defect model verified that AgCl-on-Ag NWs reduced inflammatory cell infiltration and dramatically accelerated wound healing.This work provides a synergistic mechanism based on nanosilver surface engineering to eradicate the resistant bacteria that can alleviate drug resistance and develop an innovative approach for the treatment of bacterial infections. 展开更多
关键词 Surface engineering NANOSILVER n-halamine Reactive oxygen species(ROS) Antibiotic resistance
原文传递
FUNCTIONALIZING PS MICROSPHERES BY SUPERCRITICAL DEPOSITION OF P(S-b-tBA) FOR DIVERSE INTERFACIAL PROPERTIES EXEMPLIFIED WITH BIOCIDAL ABILITY
8
作者 陈勇 《Chinese Journal of Polymer Science》 SCIE CAS CSCD 2012年第3期451-459,共9页
Polystyrene (PS) microsphel"es were functionalized with poly(styrene-b-tert-butyl acrylate) (P(S-b-tBA)) by adsorption from supereritical mixture of CO2 and hexane. Supercritical deposition formed a shell-cor... Polystyrene (PS) microsphel"es were functionalized with poly(styrene-b-tert-butyl acrylate) (P(S-b-tBA)) by adsorption from supereritical mixture of CO2 and hexane. Supercritical deposition formed a shell-core structure that contained a shell ofpoly(tert-butyl acrylate) (PtBA) blocks and a core of the PS blocks entangling with the PS microspheres. The thickness of the PtBA layer and thereby the areal density of ten-butyl ester groups increased v;ith the deposition pressure until plateau values attained at 20 MPa and higher. The tert-butyl ester groups were hydrolyzed to earboxyl groups for conjugation with tert-butylamine molecules via amide bonds that were further chlorinated into biocidal N-halamine moieties. The functionalization layer and its bonded N-halamine moieties were stable in flowing watel and the chlorine could be regenerated upon eventual loss. This functionalization concept is applicable to polymers of any external and internal surfaces to achieve diverse surface properties by varying block eopolymer and conjugated mo:ieties. 展开更多
关键词 Surface functionalization Supercritical deposition n-halamine.
原文传递
Non‑Leaching,Rapid Bactericidal and Biocompatible Polyester Fabrics Finished with Benzophenone Terminated N‑halamine 被引量:3
9
作者 Shu Wang JianNa Li +3 位作者 Yihong Cao JingWei Gu YuanFeng Wang ShiGuo Chen 《Advanced Fiber Materials》 SCIE CAS 2022年第1期119-128,共10页
Pathogenic bacteria can proliferate rapidly on porous fabrics to form bacterial plaques/bioflms,resulting in potential sources of cross-transmissions of diseases and increasing cross-infection in public environments.M... Pathogenic bacteria can proliferate rapidly on porous fabrics to form bacterial plaques/bioflms,resulting in potential sources of cross-transmissions of diseases and increasing cross-infection in public environments.Many works on antibacterial modifcation of cotton fabrics have been reported,while very few works were reported to endow poly(ethylene terephthalate)(PET)fabrics with non-leaching antibacterial function without compromising their innate physicochemical properties though PET is the most widely used fabric.Therefore,it is urgent to impart the PET fabrics with non-leaching antibacterial activity.Herein,a novel N-halamine compound,1-chloro-3-benzophenone-5,5-dimethylhydantoin(Cl-BPDMH),was developed to be covalently bonded onto PET fabrics,rendering non-leaching antibacterial activity while negligible cytotoxicity based on contact-killing principle.Bacterial was easily adhered to Cl-BPDMH fnished PET fabrics,and then it was inactivated quickly within 10 s.Furthermore,the breaking strength,breaking elongation,tearing strength,water vapor permeability,air permeability and whiteness of Cl-BPDMH fnished PET fabrics were improved obviously compared to raw PET fabrics.Hence,this work developed a facile approach to fabricate multifunctional synthetic textiles to render outstanding and rapid bactericidal activity without compromising their physicochemical properties and biocompatibility. 展开更多
关键词 Poly(ethylene terephthalate) FABRIC BACTERICIDAL n-halamine Photochemical reaction
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部