This paper systematically reviews the current applications of various spatial information technologies in CO_(2)sequestration monitoring,analyzes the challenges faced by spatial information technologies in CO_(2)seque...This paper systematically reviews the current applications of various spatial information technologies in CO_(2)sequestration monitoring,analyzes the challenges faced by spatial information technologies in CO_(2)sequestration monitoring,and prospects the development of spatial information technologies in CO_(2)sequestration monitoring.Currently,the spatial information technologies applied in CO_(2)sequestration monitoring mainly include five categories:eddy covariance method,remote sensing technology,geographic information system,Internet of Things technology,and global navigation satellite system.These technologies are involved in three aspects:monitoring data acquisition,positioning and data transmission,and data management and decision support.Challenges faced by the spatial information technologies in CO_(2)sequestration monitoring include:selecting spatial information technologies that match different monitoring purposes,different platforms,and different monitoring sites;establishing effective data storage and computing capabilities to cope with the broad sources and large volumes of monitoring data;and promoting collaborative operations by interacting and validating spatial information technologies with mature monitoring technologies.In the future,it is necessary to establish methods and standards for designing spatial information technology monitoring schemes,develop collaborative application methods for cross-scale monitoring technologies,integrate spatial information technologies with artificial intelligence and high-performance computing technologies,and accelerate the application of spatial information technologies in carbon sequestration projects in China.展开更多
In the Mediterranean region,despite bamboo being an alien species that can seriously alter plant and ani-mal biocoenosis,the area occupied by bamboo plantations continues to increase,especially for the purpose to sequ...In the Mediterranean region,despite bamboo being an alien species that can seriously alter plant and ani-mal biocoenosis,the area occupied by bamboo plantations continues to increase,especially for the purpose to seques-ter carbon(C).However,the C dynamics in the soil-plant system when bamboo is grown outside its native area are poorly understood.Here we investigated the C mitigation potential of the fast-growing Moso bamboo(Phyllostachys edulis)introduced in Italy for climate-change mitigation.We analyzed aboveground(AGB)and belowground(as root/shoot ratio)biomass,litter and soil organic C(SOC)at O-15-and 15-30-cm depths in a 4-year-old bamboo plantation in comparison with the former annual cropland on which the bamboo was established.To have an idea of the maximum C stored at an ecosystem level,a natural forest adjacent the two sites was also considered.In the plantation,C accumulation as AGB was stimulated,with 14.8±3.1 Mg C ha^(-1) stored in 3 years;because thinning was done to remove culms from the first year,the mean sequestration rate was 4.9 Mg C ha^(-1) a^(-1).The sequestration rates were high but comparable to other fast-growing tree species in Italy(e.g.,Pinus nigra).SOC was significantly higher in the bamboo plantation than in the cropland only at the 0-15 cm depth,but SOC stock did not differ.Possibly 4 years were not enough time for a clear increase in SOC,or the high nutrient uptake by bamboos might have depleted the soil nutrients,thus inhibiting the soil organic matter formation by bacteria.In comparison,the natural forest had significantly higher C levels in all the pools.For C dynamics at an ecosystem level,the bamboo plantation on the former annual cropland led to substantial C removal from the atmosphere(about 12 Mg C ha^(-1) a^(-1)).However,despite the promising C sequestration rates by bamboo,its introduction should be carefully considered due to potential ecological problems caused by this species in overexploited environments such as the Mediterranean area.展开更多
To address climate change,the world needs deep decarbonization to achieve carbon neutrality(CN),which implies net-zero human-caused CO_(2) emissions in the atmosphere.This study used emission-side drivers,including so...To address climate change,the world needs deep decarbonization to achieve carbon neutrality(CN),which implies net-zero human-caused CO_(2) emissions in the atmosphere.This study used emission-side drivers,including socioeconomic and net primary productivity(NPP)-based factors,to determine the changes in CN based on vegetation carbon sequestration in the case of China during 2001-2015.Spatial exploratory analysis as well as the combined use of production-theoretical decomposition analysis(PDA)and an econometric model were also utilized.We showed that CN was significantly spatially correlated over the study period;Yunnan,Heilongjiang,and Jilin presented positive spatial autocorrelations,whereas Guizhou showed a negative spatial autocorrelation.More than half of CN declined over the period during which potential energy intensity(PEIE)and energy usage technological change were the largest negative and positive drivers for increasing CN.PEIE played a significantly negative role in increasing CN.We advise policymakers to focus more on emission-side drivers(e.g.,energy intensity)in addition to strengthening NPP management to achieve CN.展开更多
BACKGROUND Extralobar pulmonary sequestration(ELS)with torsion is extremely rare,consequently,the diagnosis of ELS with torsion in children presents a challenge for clinicians.Herein,we report four cases of ELS with t...BACKGROUND Extralobar pulmonary sequestration(ELS)with torsion is extremely rare,consequently,the diagnosis of ELS with torsion in children presents a challenge for clinicians.Herein,we report four cases of ELS with torsion that presented with abdominal pain,and further review the relevant literature to summarize the clinical features.CASE SUMMARY Four children presented to our department with abdominal pain.All underwent chest computed tomography,which revealed an intrathoracic soft tissue mass with pleural effusion.All four children underwent thoracoscopic resection of the identified pulmonary sequestration,and the vascular pedicle was clipped and excised.None of the patients experienced any postoperative complications.CONCLUSION Clinicians should consider the possibility of ELS with torsion in children presenting with abdominal pain as the chief complaint.展开更多
Marine carbon sequestration is an important component of carbon dioxide capture, utilization and storage(CCUS) technology. It is crucial for achieving carbon peaking and carbon neutralization in China. However, CO_(2)...Marine carbon sequestration is an important component of carbon dioxide capture, utilization and storage(CCUS) technology. It is crucial for achieving carbon peaking and carbon neutralization in China. However, CO_(2) leakage may lead to seabed geological disasters and threaten the safety of marine engineering. Therefore, it is of great significance to study the safety monitoring technology of marine carbon sequestration.Zhanjiang is industrially developed and rich in carbon sources. Owing to the good physical properties and reservoirs and trap characteristics,Zhanjiang has huge storage potential. This paper explores the disaster mechanism associated with CO_(2) leakage in marine carbon sequestration areas. Based on the analysis of the development of Zhanjiang industry and relevant domestic monitoring technologies, several suggestions for safety monitoring of marine carbon sequestration are proposed: application of offshore aquaculture platforms, expansion and application of ocean observation networks, carbon sequestration safety monitoring and sensing system. Intended to build a comprehensive and multi-level safety monitoring system for marine carbon sequestration, the outcome of this study provides assistance for the development of marine carbon sequestration in China's offshore areas.展开更多
Green manure(GM)has been used to support rice production in southern China for thousands of years.However,the effects of GM on soil carbon sequestration(CS)and the carbon footprint(CF)at a regional scale remain unclea...Green manure(GM)has been used to support rice production in southern China for thousands of years.However,the effects of GM on soil carbon sequestration(CS)and the carbon footprint(CF)at a regional scale remain unclear.Therefore,we combined the datasets from long-term multisite experiments with a meta-analysis approach to quantify the potential of GM to increase the CS and reduce the CF of paddy soils in southern China.Compared with the fallow-rice practice,the GM-rice practice increased the soil C stock at a rate of 1.62 Mg CO_(2)-eq ha^(-1) yr^(-1) and reduced chemical N application by 40%with no loss in the rice yield.The total CF varied from 7.51 to 13.66 Mg CO_(2)-eq ha^(-1) yr^(-1) and was dominated by CH_(4) emissions(60.7-81.3%).GM decreased the indirect CF by 31.4%but increased the direct CH_(4) emissions by 19.6%.In the low and high CH_(4) emission scenarios,the CH_(4) emission factors of GM(EF_(gc))were 5.58 and 21.31%,respectively.The greater soil CS offset the increase in GM-derived CF in the low CH_(4) scenario,but it could not offset the CF increase in the high CH_(4) scenario.A trade-off analysis also showed that GM can simultaneously increase the CS and reduce the total CF of the rice production system when the EF_(gc) was less than 9.20%.The variation in EF_(gc) was mainly regulated by the GM application rates and water management patterns.Determining the appropriate GM application rate and drainage pattern warrant further investigation to optimize the potential of the GM-rice system to increase the CS and reduce the total CF in China.展开更多
Combined application of chemical fertilizers with organic amendments was recommended as a strategy for improving yield,soil carbon storage,and nutrient use efficiency.However,how the long-term substitution of chemical...Combined application of chemical fertilizers with organic amendments was recommended as a strategy for improving yield,soil carbon storage,and nutrient use efficiency.However,how the long-term substitution of chemical fertilizer with organic manure affects rice yield,carbon sequestration rate(CSR),and nitrogen use efficiency(NUE)while ensuring environmental safety remains unclear.This study assessed the long-term effect of substituting chemical fertilizer with organic manure on rice yield,CSR,and NUE.It also determined the optimum substitution ratio in the acidic soil of southern China.The treatments were:(i)NPK0,unfertilized control;(ii)NPK1,100%chemical nitrogen,phosphorus,and potassium fertilizer;(iii)NPKM1,70%chemical NPK fertilizer and 30%organic manure;(iv)NPKM2,50%chemical NPK fertilizer and 50%organic manure;and(v)NPKM3,30%chemical NPK fertilizer and 70%organic manure.Milk vetch and pig manure were sources of manure for early and late rice seasons,respectively.The result showed that SOC content was higher in NPKM1,NPKM2,and NPKM3 treatments than in NPK0 and NPK1 treatments.The carbon sequestration rate increased by 140,160,and 280%under NPKM1,NPKM2,and NPKM3 treatments,respectively,compared to NPK1 treatment.Grain yield was 86.1,93.1,93.6,and 96.5%higher under NPK1,NPKM1,NPKM2,and NPKM3 treatments,respectively,compared to NPK0 treatment.The NUE in NPKM1,NPKM2,and NPKM3 treatments was higher as compared to NPK1 treatment for both rice seasons.Redundancy analysis revealed close positive relationships of CSR with C input,total N,soil C:N ratio,catalase,and humic acids,whereas NUE was closely related to grain yield,grain N content,and phenol oxidase.Furthermore,CSR and NUE negatively correlated with humin acid and soil C:P and N:P ratios.The technique for order of preference by similarity to ideal solution(TOPSIS)showed that NPKM3 treatment was the optimum strategy for improving CSR and NUE.Therefore,substituting 70%of chemical fertilizer with organic manure could be the best management option for increasing CSR and NUE in the paddy fields of southern China.展开更多
Grazing exclusion is one of the primary management practices used to restore degraded grasslands on the Tibetan Plateau.However,to date,the effects of long-term grazing exclusion measures on the process of restoring d...Grazing exclusion is one of the primary management practices used to restore degraded grasslands on the Tibetan Plateau.However,to date,the effects of long-term grazing exclusion measures on the process of restoring degraded alpine meadows have not been evaluated.In this study,moderately degraded plots,in which the vegetation coverage was approximately 65%and the dominant plant species was Potentilla anserina L,with grazing exclusion for 2 to 23 years,were selected in alpine meadows of Haibei in Qinghai-Tibet Plateau.Plant coverage,plant height,biomass,soil bulk density,saturated water content,soil organic carbon(SOC)and total nitrogen(TN)were evaluated.The results were as follows:(1)With aboveground biomass and total saturated water content at 0-40 cm depth,the average SOC and TN contents in moderately degraded alpine meadows increased as a power function,and the plant height increased as a log function.(2)The average soil bulk density at 0-40 cm depth first decreased and then increased with increasing grazing exclusion duration,and the minimum value of 0.90 g·cm^(-3) was reached at 15.23 years.The plant coverage,total belowground biomass at 0-40 cm depth,total aboveground and belowground biomass first increased and then decreased,their maximum values(80.49%,2452.92g·m^(-2),2891.06 g·m^(-2))were reached at 9.41,9.46 and 10.25 years,respectively.Long-term grazing exclusion is apparently harmful for the sustainable restoration of degraded alpine meadows.The optimal duration of grazing exclusion for the restoration of moderately degraded alpine meadows was 10 years.This research suggests that moderate disturbance should be allowed in moderately degraded alpine meadows after 10years of grazing exclusion.展开更多
Despite the high efficiency that has been achieved for the perovskite solar cells(PSCs),the hazardous lead leakage from the perovskite absorber layer is one of the crucial barriers still hindering its penetration into...Despite the high efficiency that has been achieved for the perovskite solar cells(PSCs),the hazardous lead leakage from the perovskite absorber layer is one of the crucial barriers still hindering its penetration into the commercial market for a large-scale installation.Herein,we report a novel low-cost and biodegradable lead sequestration layer with high compatibility for up-scalable encapsulation of PSCs.Through a precisely designed cross-linking reaction of chemical agents,the as-made biodegradable chitosan composite film shows enhanced mechanical strength,chemical stability,and lead adsorption capacity.The designed encapsulation strategy reduces over 99.99% lead leakage to <2 ppb under varied simulations of weather conditions(hail,rain,or flood),which meet the safe level of drinking water set by the US Environmental Protection Agency(EPA).Moreover,the PSC efficiency is improved from 21.91% to22.82% due to the improved light absorption from the printed biodegradable lead absorption film.Finally,we present a prototype process of accumulation and recycling of lead compounds in PSCs derbies via the biodegradation process.Based on the low-cost biodegradable lead sequestration film,this environmental-friendly encapsulation strategy could address the lead leakage issue for further commercialization of PSCs.展开更多
Subsurface geothermal energy storage has greater potential than other energy storage strategies in terms of capacity scale and time duration.Carbon dioxide(CO_(2))is regarded as a potential medium for energy storage d...Subsurface geothermal energy storage has greater potential than other energy storage strategies in terms of capacity scale and time duration.Carbon dioxide(CO_(2))is regarded as a potential medium for energy storage due to its superior thermal properties.Moreover,the use of CO_(2)plumes for geothermal energy storage mitigates the greenhouse effect by storing CO_(2)in geological bodies.In this work,an integrated framework is proposed for synergistic geothermal energy storage and CO_(2)sequestration and utilization.Within this framework,CO_(2)is first injected into geothermal layers for energy accumulation.The resultant high-energy CO_(2)is then introduced into a target oil reservoir for CO_(2)utilization and geothermal energy storage.As a result,CO_(2)is sequestrated in the geological oil reservoir body.The results show that,as high-energy CO_(2)is injected,the average temperature of the whole target reservoir is greatly increased.With the assistance of geothermal energy,the geological utilization efficiency of CO_(2)is higher,resulting in a 10.1%increase in oil displacement efficiency.According to a storage-potential assessment of the simulated CO_(2)site,110 years after the CO_(2)injection,the utilization efficiency of the geological body will be as high as 91.2%,and the final injection quantity of the CO_(2)in the site will be as high as 9.529×10^(8)t.After 1000 years sequestration,the supercritical phase dominates in CO_(2)sequestration,followed by the liquid phase and then the mineralized phase.In addition,CO_(2)sequestration accounting for dissolution trapping increases significantly due to the presence of residual oil.More importantly,CO_(2)exhibits excellent performance in storing geothermal energy on a large scale;for example,the total energy stored in the studied geological body can provide the yearly energy supply for over 3.5×10^(7) normal households.Application of this integrated approach holds great significance for large-scale geothermal energy storage and the achievement of carbon neutrality.展开更多
Because it is necessary to focus on differences in regional oil reservoirs and determine the priority of the CCUSEOR(Carbon capture,utilization,and storage-enhanced oil recovery) deployment under China’s net-zero CO_...Because it is necessary to focus on differences in regional oil reservoirs and determine the priority of the CCUSEOR(Carbon capture,utilization,and storage-enhanced oil recovery) deployment under China’s net-zero CO_(2) emission target,systematic and regional evaluations of CO_(2) sequestration capacity in major oil basins are needed considering the geofluid properties―carbon sequestration capacity in place(CSCIP)―where the ’in place’ indicates actual geological formation conditions underground,e.g.,formation temperature and pressure.Therefore,physical properties of geofluids at different depths with different geologic temperatures and pressure conditions are considered for the CO_(2) sequestration capacity evaluation in place,including shallow(800–2000 m),medium(2000–3500 m),deep(3500–4500 m) and ultra-deep(4500–8000 m) depth intervals.A modified evaluation model with four grading levels is proposed,combining the P-V-T equations of state(EOS) and evaluation equations of the Carbon Sequestration Leadership Forum(CSLF),including theoretical,effective,practical,and CCUS-EOR CSCIP,which is more consistent with geofluid physical properties underground,to make the grading evaluation and ranking of the CSCIP in China’s major oil basins.Then,the grading CSCIP of 29 major oil basins in China was evaluated based on the petroleum resources evaluation results of the Ministry of Natural Resources of China(MNRC) during China’s 13th Five-Year Plan period.According to the grading evaluation results,suggestions for China’s CCUS-EOR prospective regions are given as follows:shallow oil fields of the Songliao Basin in Northeast China,shallow–medium oil fields of the Bohai Bay Basin in East China,medium oil fields of the Zhungeer Basin in West China,and medium oil fields of the Ordos Basin in Central China;all are potential areas for the CCUS-EOR geological sequestration in China’s onshore oil basins.In addition,in China’s offshore oil basins,shallow–medium oil fields of the Bohai Sea and shallow oil fields of the Pearl River Mouth Basin have potential for CCUS-EOR geological sequestration.展开更多
Cannabidiol (CBD), one of the most studied phytocannabinoids, is non-psychotropic and can induce protective effects on the central nervous system against acute and chronic brain injury. Interestingly, CBD inhibits pro...Cannabidiol (CBD), one of the most studied phytocannabinoids, is non-psychotropic and can induce protective effects on the central nervous system against acute and chronic brain injury. Interestingly, CBD inhibits processes relating to amyloid beta (Aβ)-induced neurotoxicity in mouse models of Alzheimer’s disease, though the detailed molecular mechanism underlying the CBD neurotoxicity modulation is not fully understood. In this study, using atomic force microscopy, we find that CBD promotes the aggregation of Aβ peptides, enhancing the formation of Aβ oligomers, also known as Aβ-derived diffusible ligands (ADDLs). The CBD-mediated sequestration of Aβ monomers in soluble ADDLs could reduce neurotoxicity. This study highlights a possible role of CBD in modulating the formation of ADDL aggregates and provides insight into potentially neuroprotective properties of CBD in Alzheimer’s disease.展开更多
The Lucaogou Formation,located in the Jimsar Sag,Junggar Basin,NW China,has great potential for shale oil resources.In the process of CO_(2)-EOR(CO_(2) enhance oil recovery),mineral dissolution,precipitation and trans...The Lucaogou Formation,located in the Jimsar Sag,Junggar Basin,NW China,has great potential for shale oil resources.In the process of CO_(2)-EOR(CO_(2) enhance oil recovery),mineral dissolution,precipitation and transformation,leading to the local corrosion or blockage of reservoirs,have a significant influence on recovery.In this study,a combination of high-temperature and high-pressure laboratory experiments and coupled temperature/fluid-chemistry multifield numerical simulations are used to investigate CO_(2)-water-rock reactions under various reservoir conditions in the upper and lower ’sweet spots’,to reveal the mechanisms underlying CO_(2)-induced mineral dissolution,precipitation and transformation.In addition,we quantitatively calculated the evolution of porosity over geological timescales;compared and analyzed the variability of CO_(2) transformation in the reservoir under a variety of temperature,lithology and solution conditions;and identified the main factors controlling CO_(2)-water-rock reactions,the types of mineral transformation occurring during long-term CO_(2) sequestration and effective carbon sequestration minerals.The results demonstrate that the main minerals undergoing dissolution under the influence of supercritical CO_(2) are feldspars,while the main minerals undergoing precipitation include carbonate rock minerals,clay minerals and quartz.Feldspar minerals,especially the initially abundant plagioclase in the formation,directly affects total carbon sequestration,feldspar-rich clastic rocks therefore having considerable sequestration potential.展开更多
The efiect of an innovative accelerated carbonation curing technique was evaluated on concrete containing natural zeolite powder and fine aggregate as partial replacement to alleviate the CO_(2) emission up to a certa...The efiect of an innovative accelerated carbonation curing technique was evaluated on concrete containing natural zeolite powder and fine aggregate as partial replacement to alleviate the CO_(2) emission up to a certain extent from the concrete production industry and improve sequestration of CO_(2) into the concrete matrix in a stable form.An accelerated carbonation curing was accomplished by subjecting the concrete specimens to 0.5 and 0.75 M concentrations of sodium bicarbonate(NaHCO_(3)) solutions up to a curing age of 180 days after the initial 28 days of normal water curing.Tests for carbonation depth,pH value,compressive strength,calcium carbonate(CaCO_(3))content,X-ray difiraction,and thermogravimetric(TGA)analyses and Fourier transform infrared spectroscopy(FTIR)were performed to measure the extent of carbonation.The obtained results showed an increment in average compressive strength for the zeolite concrete(ZLC)mixes exposed to accelerated carbonation curing.The ZLC mixes exposed to increasing NaHCO_(3) solution concentration and exposure period exhibited greater carbonation depth and decreased pH at each depth interval indicating higher CO_(2) sequestration within the concrete matrix.The results obtained from the microstructural analysis(XRD,TGA,and FTIR)and CaCO_(3) content measurements confirm that the higher amount of CaCO_(3) formation provides a clear indication of the carbonation enhancement and CO_(2) sequestration within the concrete matrix and in turn contributing to the global warming reduction.展开更多
Roadside trees are effective natural solutions for mitigating climate change. Despite the usefulness of trees to carbon sequestration, there is a dearth of information on the estimation of biomass and carbon stock for...Roadside trees are effective natural solutions for mitigating climate change. Despite the usefulness of trees to carbon sequestration, there is a dearth of information on the estimation of biomass and carbon stock for roadside trees in the study area. This study aimed to estimate the carbon stock and carbon dioxide equivalent of roadside trees. A complete enumeration of trees was carried out in Kétou, Pobè and Sakété within the communes of the Plateau Department, Bénin Republic. Total height and diameter at breast height were measured from trees along the roads while individual wood density value was obtained from wood density database. The allometric method of biomass estimation was adopted for the research. The results showed that the total estimations for above-ground biomass, carbon stock and carbon equivalent from all the enumerated roadside trees were 154.53 mt, 72.63 mt and 266.55 mt, respectively. The results imply that the roadside trees contain a substantial amount of carbon stock that can contribute to climate change mitigation through carbon sequestration.展开更多
Na^(+)/K^(+)-ATPase is a transmembrane protein that has important roles in the maintenance of electrochemical gradients across cell membranes by transporting three Na^(+)out of and two K^(+)into cells.Additionally,Na^...Na^(+)/K^(+)-ATPase is a transmembrane protein that has important roles in the maintenance of electrochemical gradients across cell membranes by transporting three Na^(+)out of and two K^(+)into cells.Additionally,Na^(+)/K^(+)-ATPase participates in Ca^(2+)-signaling transduction and neurotransmitter release by coordinating the ion concentration gradient across the cell membrane.Na^(+)/K^(+)-ATPase works synergistically with multiple ion channels in the cell membrane to form a dynamic network of ion homeostatic regulation and affects cellular communication by regulating chemical signals and the ion balance among different types of cells.Therefo re,it is not surprising that Na^(+)/K^(+)-ATPase dysfunction has emerged as a risk factor for a variety of neurological diseases.However,published studies have so far only elucidated the important roles of Na^(+)/K^(+)-ATPase dysfunction in disease development,and we are lacking detailed mechanisms to clarify how Na^(+)/K^(+)-ATPase affects cell function.Our recent studies revealed that membrane loss of Na^(+)/K^(+)-ATPase is a key mechanism in many neurological disorders,particularly stroke and Parkinson's disease.Stabilization of plasma membrane Na^(+)/K^(+)-ATPase with an antibody is a novel strategy to treat these diseases.For this reason,Na^(+)/K^(+)-ATPase acts not only as a simple ion pump but also as a sensor/regulator or cytoprotective protein,participating in signal transduction such as neuronal autophagy and apoptosis,and glial cell migration.Thus,the present review attempts to summarize the novel biological functions of Na^(+)/K^(+)-ATPase and Na^(+)/K^(+)-ATPase-related pathogenesis.The potential for novel strategies to treat Na^(+)/K^(+)-ATPase-related brain diseases will also be discussed.展开更多
The process of capturing and storing carbon dioxide (CCS) was previously considered a crucial and time-sensitive approach for diminishing CO<sub>2</sub> emissions originating from coal, oil, and gas sector...The process of capturing and storing carbon dioxide (CCS) was previously considered a crucial and time-sensitive approach for diminishing CO<sub>2</sub> emissions originating from coal, oil, and gas sectors. Its implementation was seen necessary to address the detrimental effects of CO<sub>2</sub> on the atmosphere and the ecosystem. This recognition was achieved by previous substantial study efforts. The carbon capture and storage (CCS) cycle concludes with the final stage of CO<sub>2</sub> storage. This stage involves primarily the adsorption of CO<sub>2</sub> in the ocean and the injection of CO<sub>2</sub> into subsurface reservoir formations. Additionally, the process of CO<sub>2</sub> reactivity with minerals in the reservoir formations leads to the formation of limestone through injectivities. Carbon capture and storage (CCS) is the final phase in the CCS cycle, mostly achieved by the use of marine and underground geological sequestration methods, along with mineral carbonation techniques. The introduction of supercritical CO<sub>2</sub> into geological formations has the potential to alter the prevailing physical and chemical characteristics of the subsurface environment. This process can lead to modifications in the pore fluid pressure, temperature conditions, chemical reactivity, and stress distribution within the reservoir rock. The objective of this study is to enhance our existing understanding of CO<sub>2</sub> injection and storage systems, with a specific focus on CO<sub>2</sub> storage techniques and the associated issues faced during their implementation. Additionally, this research examines strategies for mitigating important uncertainties in carbon capture and storage (CCS) practises. Carbon capture and storage (CCS) facilities can be considered as integrated systems. However, in scientific research, these storage systems are often divided based on the physical and spatial scales relevant to the investigations. Utilising the chosen system as a boundary condition is a highly effective method for segregating the physics in a diverse range of physical applications. Regrettably, the used separation technique fails to effectively depict the behaviour of the broader significant system in the context of water and gas movement within porous media. The limited efficacy of the technique in capturing the behaviour of the broader relevant system can be attributed to the intricate nature of geological subsurface systems. As a result, various carbon capture and storage (CCS) technologies have emerged, each with distinct applications, associated prices, and social and environmental implications. The results of this study have the potential to enhance comprehension regarding the selection of an appropriate carbon capture and storage (CCS) application method. Moreover, these findings can contribute to the optimisation of greenhouse gas emissions and their associated environmental consequences. By promoting process sustainability, this research can address critical challenges related to global climate change, which are currently of utmost importance to humanity. Despite the significant advancements in this technology over the past decade, various concerns and ambiguities have been highlighted. Considerable emphasis was placed on the fundamental discoveries made in practical programmes related to the storage of CO<sub>2</sub> thus far. The study has provided evidence that despite the extensive research and implementation of several CCS technologies thus far, the process of selecting an appropriate and widely accepted CCS technology remains challenging due to considerations related to its technological feasibility, economic viability, and societal and environmental acceptance.展开更多
基金Supported by the CNPC Science and Technology Major Project(2021ZZ01-05).
文摘This paper systematically reviews the current applications of various spatial information technologies in CO_(2)sequestration monitoring,analyzes the challenges faced by spatial information technologies in CO_(2)sequestration monitoring,and prospects the development of spatial information technologies in CO_(2)sequestration monitoring.Currently,the spatial information technologies applied in CO_(2)sequestration monitoring mainly include five categories:eddy covariance method,remote sensing technology,geographic information system,Internet of Things technology,and global navigation satellite system.These technologies are involved in three aspects:monitoring data acquisition,positioning and data transmission,and data management and decision support.Challenges faced by the spatial information technologies in CO_(2)sequestration monitoring include:selecting spatial information technologies that match different monitoring purposes,different platforms,and different monitoring sites;establishing effective data storage and computing capabilities to cope with the broad sources and large volumes of monitoring data;and promoting collaborative operations by interacting and validating spatial information technologies with mature monitoring technologies.In the future,it is necessary to establish methods and standards for designing spatial information technology monitoring schemes,develop collaborative application methods for cross-scale monitoring technologies,integrate spatial information technologies with artificial intelligence and high-performance computing technologies,and accelerate the application of spatial information technologies in carbon sequestration projects in China.
基金supported by the “Project funded by the European Union-Next Generation EU”
文摘In the Mediterranean region,despite bamboo being an alien species that can seriously alter plant and ani-mal biocoenosis,the area occupied by bamboo plantations continues to increase,especially for the purpose to seques-ter carbon(C).However,the C dynamics in the soil-plant system when bamboo is grown outside its native area are poorly understood.Here we investigated the C mitigation potential of the fast-growing Moso bamboo(Phyllostachys edulis)introduced in Italy for climate-change mitigation.We analyzed aboveground(AGB)and belowground(as root/shoot ratio)biomass,litter and soil organic C(SOC)at O-15-and 15-30-cm depths in a 4-year-old bamboo plantation in comparison with the former annual cropland on which the bamboo was established.To have an idea of the maximum C stored at an ecosystem level,a natural forest adjacent the two sites was also considered.In the plantation,C accumulation as AGB was stimulated,with 14.8±3.1 Mg C ha^(-1) stored in 3 years;because thinning was done to remove culms from the first year,the mean sequestration rate was 4.9 Mg C ha^(-1) a^(-1).The sequestration rates were high but comparable to other fast-growing tree species in Italy(e.g.,Pinus nigra).SOC was significantly higher in the bamboo plantation than in the cropland only at the 0-15 cm depth,but SOC stock did not differ.Possibly 4 years were not enough time for a clear increase in SOC,or the high nutrient uptake by bamboos might have depleted the soil nutrients,thus inhibiting the soil organic matter formation by bacteria.In comparison,the natural forest had significantly higher C levels in all the pools.For C dynamics at an ecosystem level,the bamboo plantation on the former annual cropland led to substantial C removal from the atmosphere(about 12 Mg C ha^(-1) a^(-1)).However,despite the promising C sequestration rates by bamboo,its introduction should be carefully considered due to potential ecological problems caused by this species in overexploited environments such as the Mediterranean area.
文摘To address climate change,the world needs deep decarbonization to achieve carbon neutrality(CN),which implies net-zero human-caused CO_(2) emissions in the atmosphere.This study used emission-side drivers,including socioeconomic and net primary productivity(NPP)-based factors,to determine the changes in CN based on vegetation carbon sequestration in the case of China during 2001-2015.Spatial exploratory analysis as well as the combined use of production-theoretical decomposition analysis(PDA)and an econometric model were also utilized.We showed that CN was significantly spatially correlated over the study period;Yunnan,Heilongjiang,and Jilin presented positive spatial autocorrelations,whereas Guizhou showed a negative spatial autocorrelation.More than half of CN declined over the period during which potential energy intensity(PEIE)and energy usage technological change were the largest negative and positive drivers for increasing CN.PEIE played a significantly negative role in increasing CN.We advise policymakers to focus more on emission-side drivers(e.g.,energy intensity)in addition to strengthening NPP management to achieve CN.
基金Supported by Shenzhen Fund for Guangdong Provincial High-level Clinical Key Specialties,No.SZGSP012Shenzhen Key Medical Discipline Construction Fund,No.SZXK032.
文摘BACKGROUND Extralobar pulmonary sequestration(ELS)with torsion is extremely rare,consequently,the diagnosis of ELS with torsion in children presents a challenge for clinicians.Herein,we report four cases of ELS with torsion that presented with abdominal pain,and further review the relevant literature to summarize the clinical features.CASE SUMMARY Four children presented to our department with abdominal pain.All underwent chest computed tomography,which revealed an intrathoracic soft tissue mass with pleural effusion.All four children underwent thoracoscopic resection of the identified pulmonary sequestration,and the vascular pedicle was clipped and excised.None of the patients experienced any postoperative complications.CONCLUSION Clinicians should consider the possibility of ELS with torsion in children presenting with abdominal pain as the chief complaint.
文摘Marine carbon sequestration is an important component of carbon dioxide capture, utilization and storage(CCUS) technology. It is crucial for achieving carbon peaking and carbon neutralization in China. However, CO_(2) leakage may lead to seabed geological disasters and threaten the safety of marine engineering. Therefore, it is of great significance to study the safety monitoring technology of marine carbon sequestration.Zhanjiang is industrially developed and rich in carbon sources. Owing to the good physical properties and reservoirs and trap characteristics,Zhanjiang has huge storage potential. This paper explores the disaster mechanism associated with CO_(2) leakage in marine carbon sequestration areas. Based on the analysis of the development of Zhanjiang industry and relevant domestic monitoring technologies, several suggestions for safety monitoring of marine carbon sequestration are proposed: application of offshore aquaculture platforms, expansion and application of ocean observation networks, carbon sequestration safety monitoring and sensing system. Intended to build a comprehensive and multi-level safety monitoring system for marine carbon sequestration, the outcome of this study provides assistance for the development of marine carbon sequestration in China's offshore areas.
基金supported by the National Key Research and Development Program of China(2021YFD1700200)the earmarked fund for China Agriculture Research System(CARS-22).
文摘Green manure(GM)has been used to support rice production in southern China for thousands of years.However,the effects of GM on soil carbon sequestration(CS)and the carbon footprint(CF)at a regional scale remain unclear.Therefore,we combined the datasets from long-term multisite experiments with a meta-analysis approach to quantify the potential of GM to increase the CS and reduce the CF of paddy soils in southern China.Compared with the fallow-rice practice,the GM-rice practice increased the soil C stock at a rate of 1.62 Mg CO_(2)-eq ha^(-1) yr^(-1) and reduced chemical N application by 40%with no loss in the rice yield.The total CF varied from 7.51 to 13.66 Mg CO_(2)-eq ha^(-1) yr^(-1) and was dominated by CH_(4) emissions(60.7-81.3%).GM decreased the indirect CF by 31.4%but increased the direct CH_(4) emissions by 19.6%.In the low and high CH_(4) emission scenarios,the CH_(4) emission factors of GM(EF_(gc))were 5.58 and 21.31%,respectively.The greater soil CS offset the increase in GM-derived CF in the low CH_(4) scenario,but it could not offset the CF increase in the high CH_(4) scenario.A trade-off analysis also showed that GM can simultaneously increase the CS and reduce the total CF of the rice production system when the EF_(gc) was less than 9.20%.The variation in EF_(gc) was mainly regulated by the GM application rates and water management patterns.Determining the appropriate GM application rate and drainage pattern warrant further investigation to optimize the potential of the GM-rice system to increase the CS and reduce the total CF in China.
基金supported by the National Natural Science Foundation of China (41671301)the National Key Research and Development Program of China (2016YFD0300901)the Central Public-interest Scientific Institution Basal Research Fund, China (GY2022-13-5, G2022-02-2, G2022-02-3 and G2022-02-10)
文摘Combined application of chemical fertilizers with organic amendments was recommended as a strategy for improving yield,soil carbon storage,and nutrient use efficiency.However,how the long-term substitution of chemical fertilizer with organic manure affects rice yield,carbon sequestration rate(CSR),and nitrogen use efficiency(NUE)while ensuring environmental safety remains unclear.This study assessed the long-term effect of substituting chemical fertilizer with organic manure on rice yield,CSR,and NUE.It also determined the optimum substitution ratio in the acidic soil of southern China.The treatments were:(i)NPK0,unfertilized control;(ii)NPK1,100%chemical nitrogen,phosphorus,and potassium fertilizer;(iii)NPKM1,70%chemical NPK fertilizer and 30%organic manure;(iv)NPKM2,50%chemical NPK fertilizer and 50%organic manure;and(v)NPKM3,30%chemical NPK fertilizer and 70%organic manure.Milk vetch and pig manure were sources of manure for early and late rice seasons,respectively.The result showed that SOC content was higher in NPKM1,NPKM2,and NPKM3 treatments than in NPK0 and NPK1 treatments.The carbon sequestration rate increased by 140,160,and 280%under NPKM1,NPKM2,and NPKM3 treatments,respectively,compared to NPK1 treatment.Grain yield was 86.1,93.1,93.6,and 96.5%higher under NPK1,NPKM1,NPKM2,and NPKM3 treatments,respectively,compared to NPK0 treatment.The NUE in NPKM1,NPKM2,and NPKM3 treatments was higher as compared to NPK1 treatment for both rice seasons.Redundancy analysis revealed close positive relationships of CSR with C input,total N,soil C:N ratio,catalase,and humic acids,whereas NUE was closely related to grain yield,grain N content,and phenol oxidase.Furthermore,CSR and NUE negatively correlated with humin acid and soil C:P and N:P ratios.The technique for order of preference by similarity to ideal solution(TOPSIS)showed that NPKM3 treatment was the optimum strategy for improving CSR and NUE.Therefore,substituting 70%of chemical fertilizer with organic manure could be the best management option for increasing CSR and NUE in the paddy fields of southern China.
基金funded by the National Natural Science Foundation of China(32001149,U20A2006,31971507)Applied Basic Research Project of Qinghai Province(2022-ZJ-716)+3 种基金Youth Innovation Promotion Association CAS(2022436)Joint Grant from Chinese Academy of Sciences-People’s Government of Qinghai Province on Sanjiangyuan National Park(LHZX-2020-07)Chinese Academy of Science(CAS)"Light of West China"Program(2018)"The effect of grazing on grassland productivity in the basin of Qinghai Lake"。
文摘Grazing exclusion is one of the primary management practices used to restore degraded grasslands on the Tibetan Plateau.However,to date,the effects of long-term grazing exclusion measures on the process of restoring degraded alpine meadows have not been evaluated.In this study,moderately degraded plots,in which the vegetation coverage was approximately 65%and the dominant plant species was Potentilla anserina L,with grazing exclusion for 2 to 23 years,were selected in alpine meadows of Haibei in Qinghai-Tibet Plateau.Plant coverage,plant height,biomass,soil bulk density,saturated water content,soil organic carbon(SOC)and total nitrogen(TN)were evaluated.The results were as follows:(1)With aboveground biomass and total saturated water content at 0-40 cm depth,the average SOC and TN contents in moderately degraded alpine meadows increased as a power function,and the plant height increased as a log function.(2)The average soil bulk density at 0-40 cm depth first decreased and then increased with increasing grazing exclusion duration,and the minimum value of 0.90 g·cm^(-3) was reached at 15.23 years.The plant coverage,total belowground biomass at 0-40 cm depth,total aboveground and belowground biomass first increased and then decreased,their maximum values(80.49%,2452.92g·m^(-2),2891.06 g·m^(-2))were reached at 9.41,9.46 and 10.25 years,respectively.Long-term grazing exclusion is apparently harmful for the sustainable restoration of degraded alpine meadows.The optimal duration of grazing exclusion for the restoration of moderately degraded alpine meadows was 10 years.This research suggests that moderate disturbance should be allowed in moderately degraded alpine meadows after 10years of grazing exclusion.
基金financially supported by the National Key Research and Development Plan (2019YFE0107200)the National Natural Science Foundation of China (52072284)the Foshan Xianhu Laboratory of the Advanced Energy Science and Technology Guangdong Laboratory (XHD2020-001)。
文摘Despite the high efficiency that has been achieved for the perovskite solar cells(PSCs),the hazardous lead leakage from the perovskite absorber layer is one of the crucial barriers still hindering its penetration into the commercial market for a large-scale installation.Herein,we report a novel low-cost and biodegradable lead sequestration layer with high compatibility for up-scalable encapsulation of PSCs.Through a precisely designed cross-linking reaction of chemical agents,the as-made biodegradable chitosan composite film shows enhanced mechanical strength,chemical stability,and lead adsorption capacity.The designed encapsulation strategy reduces over 99.99% lead leakage to <2 ppb under varied simulations of weather conditions(hail,rain,or flood),which meet the safe level of drinking water set by the US Environmental Protection Agency(EPA).Moreover,the PSC efficiency is improved from 21.91% to22.82% due to the improved light absorption from the printed biodegradable lead absorption film.Finally,we present a prototype process of accumulation and recycling of lead compounds in PSCs derbies via the biodegradation process.Based on the low-cost biodegradable lead sequestration film,this environmental-friendly encapsulation strategy could address the lead leakage issue for further commercialization of PSCs.
基金supported by the National Key Research and Development Program of China under grant(2022YFE0206700)the financial support by the National Natural Science Foundation of China(52004320)the Science Foundation of China University of Petroleum,Beijing(2462021QNXZ012 and 2462021YJRC012)。
文摘Subsurface geothermal energy storage has greater potential than other energy storage strategies in terms of capacity scale and time duration.Carbon dioxide(CO_(2))is regarded as a potential medium for energy storage due to its superior thermal properties.Moreover,the use of CO_(2)plumes for geothermal energy storage mitigates the greenhouse effect by storing CO_(2)in geological bodies.In this work,an integrated framework is proposed for synergistic geothermal energy storage and CO_(2)sequestration and utilization.Within this framework,CO_(2)is first injected into geothermal layers for energy accumulation.The resultant high-energy CO_(2)is then introduced into a target oil reservoir for CO_(2)utilization and geothermal energy storage.As a result,CO_(2)is sequestrated in the geological oil reservoir body.The results show that,as high-energy CO_(2)is injected,the average temperature of the whole target reservoir is greatly increased.With the assistance of geothermal energy,the geological utilization efficiency of CO_(2)is higher,resulting in a 10.1%increase in oil displacement efficiency.According to a storage-potential assessment of the simulated CO_(2)site,110 years after the CO_(2)injection,the utilization efficiency of the geological body will be as high as 91.2%,and the final injection quantity of the CO_(2)in the site will be as high as 9.529×10^(8)t.After 1000 years sequestration,the supercritical phase dominates in CO_(2)sequestration,followed by the liquid phase and then the mineralized phase.In addition,CO_(2)sequestration accounting for dissolution trapping increases significantly due to the presence of residual oil.More importantly,CO_(2)exhibits excellent performance in storing geothermal energy on a large scale;for example,the total energy stored in the studied geological body can provide the yearly energy supply for over 3.5×10^(7) normal households.Application of this integrated approach holds great significance for large-scale geothermal energy storage and the achievement of carbon neutrality.
基金the support of the National Natural Science Foundation of China (Grant Nos. U2244207, 42202179 and 52104034)the Fundamental Research Funds from Southwest Jiaotong University (Grant Nos. 2682023ZTPY030 and 2682022KJ034)。
文摘Because it is necessary to focus on differences in regional oil reservoirs and determine the priority of the CCUSEOR(Carbon capture,utilization,and storage-enhanced oil recovery) deployment under China’s net-zero CO_(2) emission target,systematic and regional evaluations of CO_(2) sequestration capacity in major oil basins are needed considering the geofluid properties―carbon sequestration capacity in place(CSCIP)―where the ’in place’ indicates actual geological formation conditions underground,e.g.,formation temperature and pressure.Therefore,physical properties of geofluids at different depths with different geologic temperatures and pressure conditions are considered for the CO_(2) sequestration capacity evaluation in place,including shallow(800–2000 m),medium(2000–3500 m),deep(3500–4500 m) and ultra-deep(4500–8000 m) depth intervals.A modified evaluation model with four grading levels is proposed,combining the P-V-T equations of state(EOS) and evaluation equations of the Carbon Sequestration Leadership Forum(CSLF),including theoretical,effective,practical,and CCUS-EOR CSCIP,which is more consistent with geofluid physical properties underground,to make the grading evaluation and ranking of the CSCIP in China’s major oil basins.Then,the grading CSCIP of 29 major oil basins in China was evaluated based on the petroleum resources evaluation results of the Ministry of Natural Resources of China(MNRC) during China’s 13th Five-Year Plan period.According to the grading evaluation results,suggestions for China’s CCUS-EOR prospective regions are given as follows:shallow oil fields of the Songliao Basin in Northeast China,shallow–medium oil fields of the Bohai Bay Basin in East China,medium oil fields of the Zhungeer Basin in West China,and medium oil fields of the Ordos Basin in Central China;all are potential areas for the CCUS-EOR geological sequestration in China’s onshore oil basins.In addition,in China’s offshore oil basins,shallow–medium oil fields of the Bohai Sea and shallow oil fields of the Pearl River Mouth Basin have potential for CCUS-EOR geological sequestration.
文摘Cannabidiol (CBD), one of the most studied phytocannabinoids, is non-psychotropic and can induce protective effects on the central nervous system against acute and chronic brain injury. Interestingly, CBD inhibits processes relating to amyloid beta (Aβ)-induced neurotoxicity in mouse models of Alzheimer’s disease, though the detailed molecular mechanism underlying the CBD neurotoxicity modulation is not fully understood. In this study, using atomic force microscopy, we find that CBD promotes the aggregation of Aβ peptides, enhancing the formation of Aβ oligomers, also known as Aβ-derived diffusible ligands (ADDLs). The CBD-mediated sequestration of Aβ monomers in soluble ADDLs could reduce neurotoxicity. This study highlights a possible role of CBD in modulating the formation of ADDL aggregates and provides insight into potentially neuroprotective properties of CBD in Alzheimer’s disease.
基金funded by grants from the Beijing Natural Science Foundation (Grant No. 8232044)the Natural Science Foundation of the Xinjiang Uygur Autonomous Region (Grant No. 2021D01F38)China Geological Survey Second-level Project (Grant No. DD20230025)。
文摘The Lucaogou Formation,located in the Jimsar Sag,Junggar Basin,NW China,has great potential for shale oil resources.In the process of CO_(2)-EOR(CO_(2) enhance oil recovery),mineral dissolution,precipitation and transformation,leading to the local corrosion or blockage of reservoirs,have a significant influence on recovery.In this study,a combination of high-temperature and high-pressure laboratory experiments and coupled temperature/fluid-chemistry multifield numerical simulations are used to investigate CO_(2)-water-rock reactions under various reservoir conditions in the upper and lower ’sweet spots’,to reveal the mechanisms underlying CO_(2)-induced mineral dissolution,precipitation and transformation.In addition,we quantitatively calculated the evolution of porosity over geological timescales;compared and analyzed the variability of CO_(2) transformation in the reservoir under a variety of temperature,lithology and solution conditions;and identified the main factors controlling CO_(2)-water-rock reactions,the types of mineral transformation occurring during long-term CO_(2) sequestration and effective carbon sequestration minerals.The results demonstrate that the main minerals undergoing dissolution under the influence of supercritical CO_(2) are feldspars,while the main minerals undergoing precipitation include carbonate rock minerals,clay minerals and quartz.Feldspar minerals,especially the initially abundant plagioclase in the formation,directly affects total carbon sequestration,feldspar-rich clastic rocks therefore having considerable sequestration potential.
文摘The efiect of an innovative accelerated carbonation curing technique was evaluated on concrete containing natural zeolite powder and fine aggregate as partial replacement to alleviate the CO_(2) emission up to a certain extent from the concrete production industry and improve sequestration of CO_(2) into the concrete matrix in a stable form.An accelerated carbonation curing was accomplished by subjecting the concrete specimens to 0.5 and 0.75 M concentrations of sodium bicarbonate(NaHCO_(3)) solutions up to a curing age of 180 days after the initial 28 days of normal water curing.Tests for carbonation depth,pH value,compressive strength,calcium carbonate(CaCO_(3))content,X-ray difiraction,and thermogravimetric(TGA)analyses and Fourier transform infrared spectroscopy(FTIR)were performed to measure the extent of carbonation.The obtained results showed an increment in average compressive strength for the zeolite concrete(ZLC)mixes exposed to accelerated carbonation curing.The ZLC mixes exposed to increasing NaHCO_(3) solution concentration and exposure period exhibited greater carbonation depth and decreased pH at each depth interval indicating higher CO_(2) sequestration within the concrete matrix.The results obtained from the microstructural analysis(XRD,TGA,and FTIR)and CaCO_(3) content measurements confirm that the higher amount of CaCO_(3) formation provides a clear indication of the carbonation enhancement and CO_(2) sequestration within the concrete matrix and in turn contributing to the global warming reduction.
文摘Roadside trees are effective natural solutions for mitigating climate change. Despite the usefulness of trees to carbon sequestration, there is a dearth of information on the estimation of biomass and carbon stock for roadside trees in the study area. This study aimed to estimate the carbon stock and carbon dioxide equivalent of roadside trees. A complete enumeration of trees was carried out in Kétou, Pobè and Sakété within the communes of the Plateau Department, Bénin Republic. Total height and diameter at breast height were measured from trees along the roads while individual wood density value was obtained from wood density database. The allometric method of biomass estimation was adopted for the research. The results showed that the total estimations for above-ground biomass, carbon stock and carbon equivalent from all the enumerated roadside trees were 154.53 mt, 72.63 mt and 266.55 mt, respectively. The results imply that the roadside trees contain a substantial amount of carbon stock that can contribute to climate change mitigation through carbon sequestration.
基金supported by the National Natural Science Foundation of China,No.82173800 (to JB)Shenzhen Science and Technology Program,No.KQTD20200820113040070 (to JB)。
文摘Na^(+)/K^(+)-ATPase is a transmembrane protein that has important roles in the maintenance of electrochemical gradients across cell membranes by transporting three Na^(+)out of and two K^(+)into cells.Additionally,Na^(+)/K^(+)-ATPase participates in Ca^(2+)-signaling transduction and neurotransmitter release by coordinating the ion concentration gradient across the cell membrane.Na^(+)/K^(+)-ATPase works synergistically with multiple ion channels in the cell membrane to form a dynamic network of ion homeostatic regulation and affects cellular communication by regulating chemical signals and the ion balance among different types of cells.Therefo re,it is not surprising that Na^(+)/K^(+)-ATPase dysfunction has emerged as a risk factor for a variety of neurological diseases.However,published studies have so far only elucidated the important roles of Na^(+)/K^(+)-ATPase dysfunction in disease development,and we are lacking detailed mechanisms to clarify how Na^(+)/K^(+)-ATPase affects cell function.Our recent studies revealed that membrane loss of Na^(+)/K^(+)-ATPase is a key mechanism in many neurological disorders,particularly stroke and Parkinson's disease.Stabilization of plasma membrane Na^(+)/K^(+)-ATPase with an antibody is a novel strategy to treat these diseases.For this reason,Na^(+)/K^(+)-ATPase acts not only as a simple ion pump but also as a sensor/regulator or cytoprotective protein,participating in signal transduction such as neuronal autophagy and apoptosis,and glial cell migration.Thus,the present review attempts to summarize the novel biological functions of Na^(+)/K^(+)-ATPase and Na^(+)/K^(+)-ATPase-related pathogenesis.The potential for novel strategies to treat Na^(+)/K^(+)-ATPase-related brain diseases will also be discussed.
文摘The process of capturing and storing carbon dioxide (CCS) was previously considered a crucial and time-sensitive approach for diminishing CO<sub>2</sub> emissions originating from coal, oil, and gas sectors. Its implementation was seen necessary to address the detrimental effects of CO<sub>2</sub> on the atmosphere and the ecosystem. This recognition was achieved by previous substantial study efforts. The carbon capture and storage (CCS) cycle concludes with the final stage of CO<sub>2</sub> storage. This stage involves primarily the adsorption of CO<sub>2</sub> in the ocean and the injection of CO<sub>2</sub> into subsurface reservoir formations. Additionally, the process of CO<sub>2</sub> reactivity with minerals in the reservoir formations leads to the formation of limestone through injectivities. Carbon capture and storage (CCS) is the final phase in the CCS cycle, mostly achieved by the use of marine and underground geological sequestration methods, along with mineral carbonation techniques. The introduction of supercritical CO<sub>2</sub> into geological formations has the potential to alter the prevailing physical and chemical characteristics of the subsurface environment. This process can lead to modifications in the pore fluid pressure, temperature conditions, chemical reactivity, and stress distribution within the reservoir rock. The objective of this study is to enhance our existing understanding of CO<sub>2</sub> injection and storage systems, with a specific focus on CO<sub>2</sub> storage techniques and the associated issues faced during their implementation. Additionally, this research examines strategies for mitigating important uncertainties in carbon capture and storage (CCS) practises. Carbon capture and storage (CCS) facilities can be considered as integrated systems. However, in scientific research, these storage systems are often divided based on the physical and spatial scales relevant to the investigations. Utilising the chosen system as a boundary condition is a highly effective method for segregating the physics in a diverse range of physical applications. Regrettably, the used separation technique fails to effectively depict the behaviour of the broader significant system in the context of water and gas movement within porous media. The limited efficacy of the technique in capturing the behaviour of the broader relevant system can be attributed to the intricate nature of geological subsurface systems. As a result, various carbon capture and storage (CCS) technologies have emerged, each with distinct applications, associated prices, and social and environmental implications. The results of this study have the potential to enhance comprehension regarding the selection of an appropriate carbon capture and storage (CCS) application method. Moreover, these findings can contribute to the optimisation of greenhouse gas emissions and their associated environmental consequences. By promoting process sustainability, this research can address critical challenges related to global climate change, which are currently of utmost importance to humanity. Despite the significant advancements in this technology over the past decade, various concerns and ambiguities have been highlighted. Considerable emphasis was placed on the fundamental discoveries made in practical programmes related to the storage of CO<sub>2</sub> thus far. The study has provided evidence that despite the extensive research and implementation of several CCS technologies thus far, the process of selecting an appropriate and widely accepted CCS technology remains challenging due to considerations related to its technological feasibility, economic viability, and societal and environmental acceptance.